Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Christoph Kellendonk"'
Autor:
Eduardo F. Gallo, Peter D. Balsam, Eleanor H. Simpson, Jonathan A. Javitch, Christoph Kellendonk
Publikováno v:
Mol Psychiatry
It was first posited, more than five decades ago, that the etiology of schizophrenia involves overstimulation of dopamine receptors. Since then, advanced clinical research methods, including brain imaging, have refined our understanding of the relati
Autor:
Holly Moore, Travis J Morgenstern, Gary J. Schwartz, Matthias Quick, David R. Sibley, Jonathan A. Javitch, Despoina Aslanoglou, Zachary Freyberg, Denise Sorisio, Christoph Kellendonk, Paul L. Harris, Antonella Maffei, R. Benjamin Free, Benjamin P. Inbar, Pattama Wiriyasermkul, Lori M. Zeltser, Eugene V. Mosharov, Robin Freyberg, Claudia Schmauss, Prashant Donthamsetti, Alain J. De Solis, Zachary J. Farino
Publikováno v:
Molecular psychiatry
Although long-studied in the central nervous system, there is increasing evidence that dopamine (DA) has important roles in the periphery including in metabolic regulation. Insulin-secreting pancreatic β-cells express the machinery for DA synthesis
Autor:
Christoph Kellendonk, Andrea M. Sartori, Eleanor H. Simpson, Oliver Weinmann, Marie A. Labouesse, Ulrike Weber-Stadlbauer
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 115(41)
Dopaminergic signaling in the striatum, particularly at dopamine 2 receptors (D2R), has been a topic of active investigation in obesity research in the past decades. However, it still remains unclear whether variations in striatal D2Rs modulate the r
Autor:
Prashant Donthamsetti, Kim A. Neve, Christoph Kellendonk, David C Buck, Eduardo F. Gallo, Laura M. Bohn, Edward L. Stahl, J. Robert Lane, Jonathan A. Javitch, Ying Zhu
Publikováno v:
Molecular psychiatry
SUMMARY The dopamine (DA) D2 receptor (D2R) is an important target for the treatment of neuropsychiatric disorders such as schizophrenia and Parkinson’s disease. However, the development of improved therapeutic strategies has been hampered by our i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bd51c99ec034472cbeb967890fd77c6
https://nottingham-repository.worktribe.com/file/1339495/1/nihms-977826
https://nottingham-repository.worktribe.com/file/1339495/1/nihms-977826
Autor:
Jozsef Meszaros, Pierre Trifilieff, Dominik Biezonski, Christoph Kellendonk, Jonathan A. Javitch
Publikováno v:
Journal of Comparative Neurology. 523:1175-1189
The striatum is the major input nucleus of the basal ganglia involved in reward processing, goal-directed behaviors, habit learning, and motor control. The striatum projects to the basal ganglia output nuclei via the "direct" and "indirect" pathways,
Autor:
Dominik Biezonski, Christoph Kellendonk, Eric R. Kandel, Eleanor H. Simpson, Iram Haq, Vanessa Winiger
Publikováno v:
Biological Psychiatry. 76:823-831
Background: Evidence indicating an increase in dopamine D2 receptor (D2R) density and occupancy in patients with schizophrenia comes from positron emission tomography studies using ligands that bind both D2Rs and dopamine D3 receptors (D3Rs), questio
Autor:
Alex Dranovsky, Bruno P. Guiard, Alain M. Gardier, Sarah E. Canetta, Qingyuan Meng, E. David Leonardo, Alvaro L. Garcia-Garcia, Christoph Kellendonk
Publikováno v:
Cell Reports, Vol 18, Iss 5, Pp 1144-1156 (2017)
Lifelong homeostatic setpoints for mood-related behaviors emerge during adolescence. Serotonin (5-HT) plays an important role in refining the formation of brain circuits during sensitive developmental periods. In rodents, the role of 5-HT1A receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70598c4131183faa5c7ad9cf2934dd3f
https://europepmc.org/articles/PMC5325088/
https://europepmc.org/articles/PMC5325088/
Autor:
Denise Sorisio, Alain J. De Solis, Robin Freyberg, Travis J Morgenstern, Prashant Donthamsetti, David R. Sibley, Paul L. Harris, Zachary J. Farino, Despoina Aslanoglou, Eugene V. Mosharov, Zachary Freyberg, Holly Moore, Benjamin P. Inbar, R. Benjamin Free, Antonella Maffei, Gary E. Schwartz, Matthias Quick, Pattama Wiriyasermkul, Claudia Schmauss, Lori M. Zeltser, Christoph Kellendonk, Jonathan A. Javitch
Publikováno v:
Biological Psychiatry. 85:S21
Publikováno v:
Journal of Neuroscience
Journal of Neuroscience, Society for Neuroscience, 2012, ⟨10.1523/JNEUROSCI.6056-11.2012⟩
Journal of Neuroscience, Society for Neuroscience, 2012, ⟨10.1523/JNEUROSCI.6056-11.2012⟩
Structural plasticity in the adult brain is essential for adaptive behaviors and is thought to contribute to a variety of neurological and psychiatric disorders. Medium spiny neurons of the striatum show a high degree of structural plasticity that is
Autor:
Roger J. Colbran, Devon L. Graham, Kai C. Sonntag, Hideaki Yano, Harshad D. Vishwasrao, Pierre Trifilieff, Jozsef Meszaros, Christoph Kellendonk, David R. Sibley, Eneko Urizar, Dominik Biezonski, Jonathan A. Javitch, Gregg D. Stanwood, Aliya L. Frederick
Publikováno v:
Molecular Psychiatry
Molecular Psychiatry, Nature Publishing Group, 2015, 20 (11), pp.1373-1385. ⟨10.1038/mp.2014.166⟩
Molecular psychiatry
Molecular Psychiatry, Nature Publishing Group, 2015, 20 (11), pp.1373-1385. ⟨10.1038/mp.2014.166⟩
Molecular psychiatry
International audience; Hetero-oligomers of G-protein-coupled receptors have become the subject of intense investigation, because their purported potential to manifest signaling and pharmacological properties that differ from the component receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94302edeeeed42d80e2f446f4179e6f0
https://hal.inrae.fr/hal-02636137
https://hal.inrae.fr/hal-02636137