Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Aniella Abi-Gerges"'
Autor:
Delphine Mika, Magali Samia El Hayek, Pia Hachem, Nassim Fares, A. Varin, Carole Dagher-Hamalian, Wared Nour-Eldine, Laetitia Pereira, Grégoire Vandecasteele, Rita Hanna, Pamela Abou-Khalil, Aniella Abi-Gerges, Youakim Saliba
Publikováno v:
Life sciences. 283
Aim Diabetic cardiomyopathy (DCM) accomodates a spectrum of cardiac abnormalities. This study aims to investigate whether DCM is associated with changes in cyclic adenosine 3′-5′ monophosphate (cAMP) signaling, particularly cyclic nucleotide phos
Autor:
Aniella Abi-Gerges, Liliana R. V. Castro, Jérôme Leroy, Valérie Domergue, Grégoire Vandecasteele, Rodolphe Fischmeister
Publikováno v:
Journal of Molecular and Cellular Cardiology
Journal of Molecular and Cellular Cardiology, Elsevier, 2021, 150, pp.109-121. ⟨10.1016/j.yjmcc.2020.10.011⟩
Journal of Molecular and Cellular Cardiology, Elsevier, 2021, 150, pp.109-121. ⟨10.1016/j.yjmcc.2020.10.011⟩
International audience; Background In cardiomyocytes, phosphodiesterases (PDEs) type 3 and 4 are the predominant enzymes that degrade cAMP generated by β-adrenergic receptors (β-ARs), impacting notably the regulation of the L-type Ca2+ current (ICa
Autor:
Rodolphe Fischmeister, Audrey Varin, Grégoire Vandecasteele, Florence Lefebvre, Jane-Lise Samuel, Claire Lugnier, Aniella Abi-Gerges, Philippe Mateo, Christophe Heymes, Wito Richter, Marco Conti
Publikováno v:
Circulation Research
Circulation Research, American Heart Association, 2009, 105 (8), pp.784-792. ⟨10.1161/CIRCRESAHA.109.197947⟩
Circulation Research, American Heart Association, 2009, 105 (8), pp.784-792. ⟨10.1161/CIRCRESAHA.109.197947⟩
Rationale : Multiple cyclic nucleotide phosphodiesterases (PDEs) degrade cAMP in cardiomyocytes but the role of PDEs in controlling cAMP signaling during pathological cardiac hypertrophy is poorly defined. Objective : Evaluate the β-adrenergic regul