Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Hitoshi Endou"'
Autor:
Noriko Oyama, Shin Wakui, Masaru Shirai, Masao Asari, Tomoko Mutou, Hiroyuki Takahashi, Hiroshi Hano, Masaya Motohashi, Michael F. Wempe, Hitoshi Endou, Norio Kansaku
Publikováno v:
Toxicologic Pathology. 41:984-991
When 100 mg/kg/day of di( n-butyl) phthalate (DBP) was intragastrically administered to pregnant Sprague-Dawley rats throughout gestation days 12 to 21, the male pups had similar body weights with no apparent physical differences (e.g., litter size,
Autor:
Heung-Joong Kim, Kyung Jin Park, Chun Sung Kim, Joo-Cheol Park, Yoshikatsu Kanai, Moon-Jin Jeong, Do-Seon Lim, Yeong Mu Ko, Soon-Jeong Jeong, Do Kyung Kim, Hitoshi Endou
Publikováno v:
Biological and Pharmaceutical Bulletin. 31:395-399
In order to elucidate the role of the system L-type amino acid transporters (LATs) in the wound healing process of aged and young subjects, we investigated the expression of LAT1, LAT2 and their subunit 4F2hc in the skin healing process after artific
Autor:
Kiyofumi Yokoo, Hiroshi Hano, Hiroyuki Takahashi, Tomoko Muto, Yoshihiko Suzuki, Hitoshi Endou, Masakuni Furusato, Shin Wakui, Yoshikatsu Kanai
Publikováno v:
Laboratory Investigation. 86:1172-1184
Endothelial cells and pericytes play critical role in angiogenesis, which is controlled, in part, by the angiopoietin (Ang)/Tie-2 system and vascular endothelial growth factor (VEGF). Here, we investigated Ang, Tie-2, and VEGF expression within endot
Aims: The aims of this study were to determine hyperoxia effects on S-nitrosothiol (SNO) accumulation and L-type amino acid transporter 1 (LAT1) expression/function in alveolar epithelium and to determine whether hyperoxia impairs exogenous nitric ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4e109e2389a5068f7a653e5eb98acb2
https://europepmc.org/articles/PMC4202911/
https://europepmc.org/articles/PMC4202911/
Publikováno v:
Journal of Pharmaceutical Sciences. 93:2724-2732
2,4-Dichlorophenoxyacetic acid (2,4-D) is an anionic herbicide. The purpose of the present study is to examine whether organic anion transporter 3 (Oat3; Slc22a8) is solely responsible for the uptake of 2,4-D by the isolated rat choroid plexus (CP).
Autor:
Yoshikatsu Kanai, Youn Bae Kim, Jung-Hoon Yoon, Su-Gwan Kim, Hak-Kyun Kim, Ju-Hyun Park, Hitoshi Endou, Do Kyung Kim
Publikováno v:
Anatomia, Histologia, Embryologia: Journal of Veterinary Medicine Series C. 33:119-124
Certain amino acid transport systems play an important role in supplying organic nutrients to each cell and for cell proliferation during tooth development. However, the mechanisms responsible for such actions are unclear. This study demonstrated for
Autor:
Jun Fukuda, Arthit Chairoungdua, Motohide Tokunaga, Takahiro Nakata, Hiroshi Nawashiro, Hisako Ishimine, Hidetoshi Ooigawa, Yasushi Kobayashi, Shingo Tsukada, Yoshikatsu Kanai, Hitoshi Endou, Hirotaka Matsuo
Publikováno v:
Neuroscience Letters. 358:123-126
System asc transporter Asc-1, expressed in the brain, transports D- and L-serine with high affinity. To determine the localization of Asc-1 in the rat brain, we isolated a cDNA for the rat orthologue of Asc-1. The encoded protein designated as rAsc-1
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 309:226-234
The present study examined the possible role of transporters in the drug-drug interactions between methotrexate (MTX) and nonsteroidal anti-inflammatory drugs (NSAIDs) in the renal uptake process of MTX. MTX is recognized by reduced folate carrier (R
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 305:1087-1097
Our previous kinetic analyses have shown that rat organic anion transporter 1 (rOat1; Slc22a6) and rOat3 (Slc22a8) are responsible for the renal uptake of p-aminohippurate and pravastatin, respectively. In this study, their contribution to the renal
Autor:
Mariko Yamanaka, Tomoe Fujita, Masaaki Higashihara, Masataka Majima, Seok Ho Cha, Izumi Hayashi, Hitoshi Endou
Publikováno v:
International Immunopharmacology. 2:1957-1964
It is suggested that attenuation of the renal kallikrein-kinin system (KKS) involved the development of hypertension in young spontaneously hypertensive rats (SHR). In the present study, a comparison was made between young SHR and Wistar Kyoto rats (