Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Gary J. Schwartz"'
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 299:E633-E639
Our objective was to investigate whether the direct bilateral infusion of the monounsaturated fatty acid (MUFA) oleic acid (OA) within the mediobasal hypothalamus (MBH) is sufficient to reproduce the effect of administration of OA (30 nmol) in the th
Autor:
Gary J. Schwartz, Philip J. Larsen, Andreas N. Madsen, Niels Vrang, Jacob Jelsing, Esther H.E.M. van de Wall
Publikováno v:
Neuroscience Letters. 449:20-23
The selective CB1 receptor antagonist rimonabant is a novel weight control agent. Although CB1 receptors and binding sites are present in both the rodent central and peripheral nervous systems, including the afferent vagus nerve, the role of gut affe
Autor:
Tony K.T. Lam, Gary J. Schwartz, Luciano Rossetti, Carol K.L. Lam, Liora Caspi, Xiaosong Li, Madhu Chari, Evan D. Muse, Penny Y. T. Wang, Rachel A. Ross, Hiraku Ono, Roger Gutierrez-Juarez, Peter E. Light
Publikováno v:
Diabetes
OBJECTIVE—A selective rise in hypothalamic lipid metabolism and the subsequent activation of SUR1/Kir6.2 ATP-sensitive K+ (KATP) channels inhibit hepatic glucose production. The mechanisms that link the ability of hypothalamic lipid metabolism to t
Publikováno v:
Cell Metabolism. 1(1):53-61
SummaryIncreased glucose production (GP) is the major determinant of fasting hyperglycemia in diabetes mellitus. Previous studies suggested that lipid metabolism within specific hypothalamic nuclei is a biochemical sensor for nutrient availability th
Publikováno v:
Physiology & Behavior. 78:285-294
The role of vagal afferents and splanchnic fibers in nutrient-induced flavor conditioning and feeding suppression was determined. Male rats were fitted with intraduodenal (ID) catheters and given subdiaphragmatic vagal deafferentation (SDA), celiac-s
Autor:
Wolfgang Langhans, Brian J Hrupka, Gary J. Schwartz, Carlos R. Plata-Salaman, Francesca Lugarini
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 283:R862-R868
Because nonselective cycloooxygenase (COX) inhibition attenuated anorexia after lipopolysaccharide (LPS) administration, we tested the ability of resveratrol (2.5, 10, and 40 mg/kg) and NS-398 (2.5, 10, and 40 mg/kg), selective inhibitors of the two
Autor:
Jean Lud Cadet, Bartley G. Hoebel, Bruce Ladenheim, Carlo Colantuoni, Timothy H. Moran, Gary J. Schwartz, Pedro Rada, J. McCarthy, J. Schwenker
Publikováno v:
Neuroreport. 12:3549-3552
Palatable food stimulates neural systems implicated in drug dependence; thus sugar might have effects like a drug of abuse. Rats were given 25% glucose solution with chow for 12 h followed by 12 h of food deprivation each day. They doubled their gluc
Publikováno v:
Physiology & Behavior. 72:123-128
Leptin affects food intake by reducing meal size, suggesting that it may modulate the efficacy of within-meal satiety signals. To assess whether leptin would amplify the feeding inhibitory actions of a nutrient gastric preload, we compared liquid die
Publikováno v:
Regulatory Peptides. 84:101-106
The amphibian peptide bombesin (BN) and the related mammalian peptides gastrin-releasing peptide (GRP) and neuromedin B (NMB) inhibit gastric emptying in rats. Exogenous administration of BN stimulates the release of cholecystokinin (CCK), a gastroin
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 276:R1545-R1549
The mechanisms through which leptin, the protein product of the ob gene, affects food intake remain to be determined. To assess whether the actions of leptin depend on modulation of within-meal satiety signals, we measured the effect of third ventric