Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Anita, Balakrishnan"'
Publikováno v:
Annals of Surgery. 251:865-871
We set out to examine the short-term regulation of the intestinal sodium/glucose cotransporter SGLT1 by its substrate glucose and sweet taste analogs.Intestinal SGLT1 is a putative target for antidiabetic therapy; however, its physiological regulatio
Publikováno v:
The Journal of Nutrition. 140:908-914
The intestine exhibits striking diurnal rhythmicity in glucose uptake, mediated by the sodium glucose cotransporter (SGLT1); however, regulatory pathways for these rhythms remain incompletely characterized. We hypothesized that SGLT1 rhythmicity is l
Autor:
Ali Tavakkolizadeh, Anita Balakrishnan, David B. Rhoads, Adam T. Stearns, Peter J. Park, Stanley W. Ashley, Jonathan M. Dreyfuss
Publikováno v:
Annals of surgery. 255(4)
Short bowel syndrome remains a condition of high morbidity and mortality, and current therapeutic options carry significant side effects. To identify new treatments we focused on postresection changes in microRNAs--short noncoding RNAs, which suppres
Autor:
Ali Tavakkolizadeh, A. Radmanesh, Anita Balakrishnan, David B. Rhoads, Adam T. Stearns, Stanley W. Ashley
Publikováno v:
Digestive diseases and sciences. 57(5)
We previously demonstrated vagal neural pathways, specifically subdiaphragmatic afferent fibers, regulate expression of the intestinal sodium-glucose cotransporter SGLT1, the intestinal transporter responsible for absorption of dietary glucose. We hy
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 297(5)
Roux-en-Y gastric bypass (RYGB) has become the gold-standard bariatric procedure, partly because of the rapid resolution of accompanying diabetes. There is increasing evidence this is mediated by duodenal exclusion. We hypothesize that duodenal exclu
Autor:
Ali Tavakkolizadeh, Adam T. Stearns, Jan D. Rounds, Anita Balakrishnan, David B. Rhoads, Stanley W. Ashley
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 294(4)
Introduction: the intestinal Na+/glucose cotransporter (SGLT1) displays rapid anticipatory diurnal rhythms in mRNA and protein expression. The vagus nerve has been implicated in the entrainment of some transporters. We aimed to clarify the influence
Autor:
Jennifer Irani, Michael J. Giuffrida, Jan D. Rounds, Anita Balakrishnan, David B. Rhoads, Adam T. Stearns, Ali Tavakkolizadeh, Stanley W. Ashley
Publikováno v:
Surgery. 143(6)
Intestinal transport exhibits distinct diurnal rhythmicity. Understanding the mechanisms behind this may reveal new therapeutic strategies to modulate intestinal function in disease states such as diabetes and obesity, as well as short bowel syndrome