Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Xiaofeng Tian"'
Autor:
Junjun Zhou, Yan Zhao, Ruimin Sun, Jihong Yao, Dongcheng Feng, Rong Fu, Xiaofeng Tian, Zhecheng Wang, Ruiwen Wang, Li Lv
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2019 (2019)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Alcohol abuse has become common worldwide and has been recognized as a major cause of chronic alcoholic liver disease (ALD). ALD encompasses a complex process that includes a broad scope of hepatic lesions, ranging from steatosis to cirrhosis. In par
Autor:
Tong Li, Xiaofeng Tian, Guo Zu, Anlong Ji, Yang Li, Guangzhi Wang, Dongcheng Feng, Jihong Yao
Publikováno v:
World Journal of Gastroenterology
BACKGROUND Intestinal ischemia reperfusion (I/R) injury is a serious but common pathophysiological process of many diseases, resulting in a high mortality rate in clinical practice. Ubiquitin-specific protease 22 (USP22) acts as regulator of cell cyc
Autor:
Zhenlu Li, Xue Shi, Anlong Ji, Chunchun Ding, Dongyan Gao, Yang Li, Junjun Zhou, Jihong Yao, Zhecheng Wang, Dongcheng Feng, Xiaofeng Tian, Yan Zhao
Publikováno v:
Toxicology and Applied Pharmacology. 350:21-31
In recent years, alcoholic liver disease (ALD) has emerged as a growing public health problem worldwide. β-catenin plays an important role in the growth, development, regeneration and metabolic activity of the liver. Salvianolic acid A (SalA) is a w
Autor:
Junjun Zhou, Yang Li, Zhecheng Wang, Ruimin Sun, Yan Zhao, Jihong Yao, Xiaohui Kang, Rong Fu, Zhanyu Wang, Yan Hu, Ruiwen Wang, Xiaofeng Tian, Wen Shan
Publikováno v:
Br J Pharmacol
Background and purpose Hepatic fatty acid metabolism disorder, a key pathogenic mechanism underlying non-alcoholic fatty liver disease (NAFLD), is associated with the hyperacetylation of mitochondrial enzymes. Acyl-CoA synthetase family member 3 (ACS
Autor:
Li Wang, Xiaofeng Tian, Dongyan Gao, Yan Hu, Chunchun Ding, Xue Shi, Yang Li, Jihong Yao, Dongcheng Feng, Yan Zhao
Publikováno v:
Toxicology and Applied Pharmacology. 339:172-180
Carnosic acid (CA), a major bioactive component in rosemary extract, has many biological and pharmaceutical activities. Smad3 acetylation can regulate the transcription of type I α2 collagen (COL1A2), which is the major component of the extracellula
Autor:
Anlong Ji, Dongcheng Feng, Guo Zu, Jihong Yao, Fuwen Luo, Yiqi Rui, Guangzhi Wang, Zhenlu Li, Shili Ning, Yang Li, Xiaofeng Tian
Publikováno v:
Journal of Molecular Medicine. 95:83-95
Intestinal ischemia/reperfusion (I/R) injury is a potentially life-threatening condition that can cause injuries to remote organs at the end stage. The damage caused by intestinal I/R insult induces changes in the barrier functions of the intestine,
Autor:
Feng Zhang, Wei Zhou, Huanyu Zhao, Dongcheng Feng, Jihong Yao, Zhenlu Li, Xiaofeng Tian, Wenzhi Tan, Yang Li, Liwei Liu
Publikováno v:
Apoptosis : an international journal on programmed cell death. 23(11-12)
Epithelial apoptosis is an important factor in intestinal ischemia-reperfusion (I/R) injury. Heat shock factor 1 (HSF1) is a classical stress response factor that directly regulates the transcription of heat shock proteins (HSPs) under stress conditi
Autor:
Yang Lu, Yan Hu, Huirong Jing, Xiaohan Zhai, Yuan Lin, Wei Xu, Xiaofeng Tian, Dongyan Gao, Mingzhu Li, Jihong Yao
Publikováno v:
Toxicology Letters. 228:67-74
Salvianolic acid B (SalB) is isolated from the traditional Chinese medical herb salvia miltiorrhiza. It has many biological and pharmaceutical activities. This study aimed to investigate the effect of SalB on acute ethanol-induced hepatic injury in r
Autor:
Chunchun Ding, Yan Zhao, Junjun Zhou, Zhenlu Li, Xue Shi, Dongyan Gao, Li Lv, Ning Zhang, Jihong Yao, Guo Zu, Xiaofeng Tian
Publikováno v:
Scientific Reports
Salvianolic acid A (SalA), one of the most efficacious polyphenol compounds extracted from Radix Salvia miltiorrhiza (Danshen), has been shown to possess many potential pharmacological activities. This study aimed to investigate whether SalA has hepa
Autor:
Xiaochi Ma, Lili Gao, Jihong Yao, Wenjing Zeng, Zhenlu Li, Wei Xu, Jinyong Peng, Ning Zhang, Yan Hu, Wen Shan, Xiaofeng Tian, Guangzhi Wang, Dongyan Gao
Publikováno v:
Scientific Reports
The inflammatory mediator high-mobility group box 1 (HMGB1) plays a critical role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). However, the regulation of HMGB1 in NAFLD, particularly through sirtuin 1 (SIRT1), remains unclear. In