Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Tore Bengtsson"'
Autor:
Saori, Mukaida, Masaaki, Sato, Anette I, Öberg, Nodi, Dehvari, Jessica M, Olsen, Martina, Kocan, Michelle Louise, Halls, Jon, Merlin, Anna L, Sandström, Robert I, Csikasz, Bronwyn Anne, Evans, Roger James, Summers, Dana Sabine, Hutchinson, Tore, Bengtsson
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 316(5)
The type 2 diabetes epidemic makes it important to find insulin-independent ways to improve glucose homeostasis. This study examines the mechanisms activated by a dual β
Autor:
Masaaki, Sato, Bronwyn A, Evans, Anna L, Sandström, Ling Yeong, Chia, Saori, Mukaida, Bui San, Thai, Anh, Nguyen, Linzi, Lim, Christina Y R, Tan, Jo-Anne, Baltos, Paul J, White, Lauren T, May, Dana S, Hutchinson, Roger J, Summers, Tore, Bengtsson
Publikováno v:
Biochemical pharmacology. 148
The capacity of G protein-coupled receptors to modulate mechanistic target of rapamycin (mTOR) activity is a newly emerging paradigm with the potential to link cell surface receptors with cell survival. Cardiomyocyte viability is linked to signalling
Publikováno v:
Diabetologia. 50:158-167
In skeletal muscle, the storage of glycogen by insulin is regulated by glycogen synthase, which is regulated by glycogen synthase kinase 3 (GSK3). Here we examined whether adrenergic receptor activation, which can increase glucose uptake, regulates g
Autor:
Dana S. Hutchinson, Tore Bengtsson
Publikováno v:
Endocrinology. 146:901-912
The role of α1-adrenoceptor activation on glucose uptake in L6 cells was investigated. The α1-adrenoceptor agonist phenylephrine [pEC50 (−log10 EC50), 5.27 ± 0.30] or cirazoline (pEC50, 5.00 ± 0.23) increased glucose uptake in a concentration-d
Autor:
Olof S. Dallner, Tore Bengtsson, Nodi Dehvari, Roger J. Summers, Robert I. Csikasz, Dana S. Hutchinson, Masaaki Sato, Anna L. Sandström, Jessica M. Olsen, Anette I. Öberg
Publikováno v:
Diabetes. 63(12)
There is an increasing worldwide epidemic of type 2 diabetes that poses major health problems. We have identified a novel physiological system that increases glucose uptake in skeletal muscle but not in white adipocytes. Activation of this system imp
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22304 (2011)
PLoS ONE
PLoS ONE
The β-adrenoceptors (β-ARs) control many cellular processes. Here, we show that β-ARs inhibit calcium depletion-induced cell contractility and subsequent cell detachment of L6 skeletal muscle cells. The mechanism underlying the cell detachment inh
Autor:
Mona Wilcke, Claes-Göran Östenson, Robert I. Csikasz, Nodi Dehvari, Anette I. Öberg, Dana S. Hutchinson, Tore Bengtsson, Kamal Yassin, Irina G. Shabalina
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22510 (2011)
PLoS ONE
PLoS ONE
BACKGROUND: There is considerable interest in identifying compounds that can improve glucose homeostasis. Skeletal muscle, due to its large mass, is the principal organ for glucose disposal in the body and we have investigated here if shikonin, a nap
Autor:
Dana S. Hutchinson, Jon Merlin, Bronwyn A Evans, Roger J. Summers, Tore Bengtsson, Robert I. Csikasz
Publikováno v:
Cellular signalling. 22(7)
The role of muscarinic acetylcholine receptors (mAChRs) in regulating glucose uptake in L6 skeletal muscle cells was investigated. [(3)H]-2-Deoxyglucose uptake was increased in differentiated L6 cells by insulin, acetylcholine, oxotremorine-M and car
Publikováno v:
Endocrinology. 147(12)
To identify the mechanisms whereby norepinephrine induces glucose uptake in brown adipose tissue, we used mouse brown adipocytes in culture. Proliferating brown adipocytes had high levels of glucose transporter (GLUT) 1 mRNA and low levels of GLUT4 m
Autor:
Dana S, Hutchinson, Tore, Bengtsson
Publikováno v:
Diabetes. 55(3)
AMP-activated protein kinase (AMPK), which functions as a sensor of cellular energy homeostasis, was phosphorylated after norepinephrine stimulation in L6 skeletal muscle cells. This effect was mediated by alpha1-adrenoceptors, with no stimulatory ef