Zobrazeno 21 - 30
of 117
pro vyhledávání: '"Roller A"'
Autor:
Rocío García-Villalba, Francisco A. Tomás-Barberán, María-Teresa García-Conesa, Mar Larrosa, María Romo-Vaquero, María Obiol, Marc Roller, John G. Flanagan, Rocío González-Barrio, María-Victoria Selma, Nicolas Issaly
Publikováno v:
PLoS ONE
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS ONE, Vol 9, Iss 4, p e94687 (2014)
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS ONE, Vol 9, Iss 4, p e94687 (2014)
[Background] Carnosic acid (CA) and rosemary extracts (RE) show body-weight, energy metabolism and inflammation regulatory properties in animal models but the mechanisms are not yet understood. Gut microbiota plays an important role in the host metab
Autor:
M.A. Noguera, Nicolas Issaly, Fermí Montó, Maria Dolores Ivorra, Cristina Arce, John G. Flanagan, Marc Roller, Pilar D'Ocon
Publikováno v:
Foodfunction. 5(4)
Nuzhenide and GI3, the principal secoiridoids of an extract obtained from the seeds of Fraxinus excelsior L. (FXE), are believed to be the active compounds responsible for the previously reported hypoglycemic effects of this extract. In this study, t
Autor:
Anna M. Roller, Kathleen Carter, Rick C.S. Lin, Ian A. Paul, Abhay J. Bhatt, Xuemei Dai, Lir-Wan Fan, Yi Pang
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 10, p e0164403 (2016)
PLoS ONE, Vol 11, Iss 10, p e0164403 (2016)
Perinatal infection is a well-identified risk factor for a number of neurodevelopmental disorders, including brain white matter injury (WMI) and Autism Spectrum Disorders (ASD). The underlying mechanisms by which early life inflammatory events cause
Publikováno v:
Carcinogenesis. 21:1023-1029
Human malignant mesotheliomas are induced almost exclusively by fibrous dusts. The nature of interactions between fibers and target cells, and the molecular mechanisms leading to tumorigenesis, are not yet understood. Here, the mRNA expression patter
Autor:
Eric L. Moore, Scott D. Mosser, Theresa M. Williams, Rodney A. Bednar, James C. Hershey, John F. Fay, Halea A. Corcoran, Cory R. Theberge, C. Blair Zartman, Joseph P. Vacca, Samuel L. Graham, Victor K. Johnston, Christopher A. Salvatore, Shane Roller, Stefanie A. Kane, Ian M. Bell, Bradley K. Wong, Steven N. Gallicchio, Cynthia Miller-Stein
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:4740-4742
A series of tricyclic CGRP receptor antagonists was optimized in order to improve oral bioavailability. Attenuation of polar surface area and incorporation of a weakly basic indoline nitrogen led to compound 5, a potent antagonist with good oral bioa
Autor:
María J. Yáñez-Gascón, John G. Flanagan, María-Teresa García-Conesa, Francisco A. Tomás-Barberán, Mar Larrosa, María Romo-Vaquero, Nicolas Issaly, Marc Roller, Juan Carlos Espín
Publikováno v:
Molecular nutritionfood research. 58(5)
Scope: Carnosic acid (CA) and rosemary extracts (REs) have antiobesity effects but the mechanisms are not understood. We investigated some of the potential mechanisms contributing to the metabolic effects of an RE enriched in CA. Methods and results:
Akademický článek
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Akademický článek
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Autor:
Paul R. Johnson, Dallas K. Croom, Sarah R. Bullard, Sean Ross, Ronald L. Brashear, James M. Way, Christopher R. Conlee, Shane M. Hart, Carina Ammala, Vicente Samano, James B. Thompson, Doug Minick, Yun Xu, Dennis Heyer, Shane Roller, Eric E. Boros, Sarva M. Tadepalli, Peckham Gregory, Andrew J. Carpenter, Jennifer A. Kashatus, Subba Reddy Katamreddy, Howard Ray Sauls, Richard Dana Caldwell, Celia P. Briscoe
Publikováno v:
Journal of medicinal chemistry. 55(24)
GPR119 is a 7-transmembrane receptor that is expressed in the enteroendocrine cells in the intestine and in the islets of Langerhans in the pancreas. Indolines and 6,7-dihydro-5H-pyrrolo[2,3-a]pyrimidines were discovered as G protein-coupled receptor
Autor:
Juan Carlos Espín De Gea, María-Teresa García-Conesa, Marc Roller, Emilie Fromentin, Rocío García Villalba, Alvin Ibarra, Mar Larrosa, María-Josefa Yáñez-Gascón, Francisco A. Tomás-Barberán, María Romo Vaquero
Publikováno v:
PLoS ONE
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS ONE, Vol 7, Iss 6, p e39773 (2012)
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS ONE, Vol 7, Iss 6, p e39773 (2012)
[Background] Rosemary (Rosmarinus officinalis L.) extracts (REs) exhibit hepatoprotective, anti-obesity and anti-inflammatory properties and are widely used in the food industry. REs are rich in carnosic acid (CA) and carnosol which may be responsibl