Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Riccardo Brambilla"'
Autor:
Rosario Moratalla, Stefania Fasano, Riccardo Brambilla, Irene Ruiz-DeDiego, Jose Ruben Garcia-Montes, Oscar Solís, José Brea, María Isabel Loza
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
Scientific Reports
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
Increasing evidence supports a close relationship between Ras-ERK1/2 activation in the striatum and L-DOPA-induced dyskinesia (LID). ERK1/2 activation by L-DOPA takes place through the crosstalk between D1R/AC/PKA/DARPP-32 pathway and NMDA/Ras pathwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33ada8cf35aff7dfa94df96aeb87458b
https://hdl.handle.net/10347/22624
https://hdl.handle.net/10347/22624
Autor:
Rick E. Bernardi, Alessandro Papale, Riccardo Brambilla, Andrea Brancale, Livia Marrone, Ilaria Morella, Stefania Fasano, Marzia Indrigo, Francesca Marchisella, Rainer Spanagel
Publikováno v:
eLife, Vol 5 (2016)
eLife
eLife
Ras-ERK signalling in the brain plays a central role in drug addiction. However, to date, no clinically relevant inhibitor of this cascade has been tested in experimental models of addiction, a necessary step toward clinical trials. We designed two n
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1120
Memory is a high-level brain function that enables organisms to adapt their behavioral responses to the environment, hence increasing their probability of survival. The Ras-ERK pathway is a key molecular intracellular signalling cascade for memory co
Autor:
Riccardo Brambilla, C. Mazzucchelli
Publikováno v:
Scopus-Elsevier
Ras-related guanosine triphosphatases (GTPases) couple receptor activity to a number of intracellular signalling events culminating in the control of cell morphology and gene transcription. In culture cells, the best-understood Ras-dependent signalli
Autor:
Chiara Bonini, Ivan Formentini, Attilio Bondanza, Chiara Vantaggiato, Luigi Naldini, Riccardo Brambilla
Publikováno v:
Journal of Biology, Vol 5, Iss 5, p 14 (2006)
Journal of Biology
Journal of Biology
Background The mitogen-activated protein (MAP) kinases p44ERK1 and p42ERK2 are crucial components of the regulatory machinery underlying normal and malignant cell proliferation. A currently accepted model maintains that ERK1 and ERK2 are regulated si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f118208216aedf11bbe75b68fd433ba5
Publikováno v:
FEBS letters. 460(2)
The Ras-GRF1 exchange factor molecule contains in addition to the catalytic domain two pleckstrin homology (PH1 and PH2), one IQ and one Dbl homology (DH) domains. In this study we investigated the role of such additional domains. We found that a Ras
Publikováno v:
Trends in neurosciences. 22(1)
Genetic and pharmacological experiments have recently implicated several protein kinase cascades in LTP and memory formation. The small GTPases of the Ras subfamily are activated by multiple extracellular stimuli and, via a complex array of downstrea
Autor:
Vincenzo Cestari, Liliana Minichiello, Mark Ramsey, Rüdiger Klein, Alistair J. Roylance, Caroline E. Herron, Clelia Rossi-Arnaud, Emmapaola Sturani, David P. Wolfer, Gail L. White, Hans-Peter Lipp, Nerina Gnesutta, Seth G. N. Grant, Paul F. Chapman, Riccardo Brambilla
Publikováno v:
Nature. 390(6657)
Members of the Ras subfamily of small guanine-nucleotide-binding proteins are essential for controlling normal and malignant cell proliferation as well as cell differentiation. The neuronal-specific guanine-nucleotide-exchange factor, Ras-GRF/CDC25Mm
Autor:
Lilia Alberghina, Emmapaola Sturani, Paola Coccetti, Riccardo Brambilla, Renata Zippel, Cristina Ferrari, Marco Vanoni, Enzo Martegani
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
In the yeast Saccharomyces cerevisiae genetic and biochemical evidence indicates that the product of the CDC25 gene activates the RAS/adenylyl cyclase/protein kinase A pathway by acting as a guanine nucleotide protein. Here we report the isolation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f69f675f345ffb768c0987a5128d226f
http://www.scopus.com/inward/record.url?eid=2-s2.0-0026523616&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0026523616&partnerID=MN8TOARS