Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Han-kun Zhang"'
Autor:
Taleen Hanania, Han Kun Zhang, Ronald J. Lukas, Alan P. Kozikowski, J. Brek Eaton, Oluseye K. Onajole, Daniela Brunner, Li-Fang Yu, Paul Whiteaker
Publikováno v:
Journal of Medicinal Chemistry. 56:5495-5504
A 3-pyridyl ether scaffold bearing a cyclopropane-containing side chain was recently identified in our efforts to create novel antidepressants that act as partial agonists at α4β2-nicotinic acetylcholine receptors. In this study, a systematic struc
Autor:
Han Kun Zhang, Taleen Hanania, Ronald J. Lukas, J. Brek Eaton, Alan P. Kozikowski, Li-Fang Yu, Allison Fedolak, Dani Brunner
Publikováno v:
Journal of medicinal chemistry. 55(22)
In our continued efforts to develop α4β2-nicotinic acetylcholine receptor (nAChR) partial agonists as novel antidepressants having a unique mechanism of action, structure-activity relationship (SAR) exploration of certain isoxazolylpyridine ethers