Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Noriko Koizumi"'
Autor:
Emmanuel Crouzet, Zhiguo He, Olfa Ben Moussa, Marielle Mentek, Pierre‐Francois Isard, Benjamin Peyret, Fabien Forest, Philippe Gain, Noriko Koizumi, Naoki Okumura, Gilles Thuret
Publikováno v:
Acta ophthalmologicaReferences. 100(6)
To report a detailed surgical procedure of tissue engineered endothelial keratoplasty (TEEK) in a rabbit model and its postoperative evaluation.TEEKs were prepared 7 days before transplantation by seeding human or rabbit corneal endothelial cells on
Publikováno v:
Japanese Journal of Ophthalmology. 63:289-296
Hospital-prepared topical ganciclovir eye drops made from intravenous infusions are used to treat cytomegalovirus corneal endotheliitis. This study assessed the efficacy of these eye drops. Experimental study design. Ganciclovir solutions (0.5% and 1
Autor:
Shigeru Kinoshita, Makiko Nakahara, Junji Hamuro, Naoki Okumura, Ryota Inoue, Kazuya Kakutani, Noriko Koizumi
Publikováno v:
Cornea. 36:988-994
The aim of this study was to evaluate which amino acid(s) among the 20 standard protein amino acids is indispensable for the survival of cultured human corneal endothelial cells (HCECs).HCECs were cultured in amino acid screening media that were miss
Autor:
Friedrich E. Kruse, Masataka Teramoto, Ursula Schlötzer-Schrehardt, Naoki Okumura, Tomoki Shimada, Hirofumi Imai, Noriko Koizumi, Yuya Fukui, Shigeru Kinoshita, Daiki Matsumoto, Tetta Kurosawa
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191306 (2018)
PLoS ONE
PLoS ONE
Corneal transparency is maintained by the corneal endothelium through its pump and barrier function. Severe corneal endothelial damage results in dysregulation of water flow and eventually causes corneal haziness and deterioration of visual function.
Autor:
Yoshinobu Takakura, Naohiro Takemoto, Makiya Nishikawa, Heidie Frisco-Cabanos, Kosuke Kusamori, Shigeru Kinoshita, Sayumi Yamazoe, Shinichi Sato, Motonari Uesugi, Mizuki Watanabe, Noriko Koizumi, Naoki Okumura, Junichiro Takaya
Publikováno v:
Angewandte Chemie. 126:11390-11395
One of the major problems encountered in cell transplantation is the low level of survival of transplanted cells due to detachment-induced apoptosis, called anoikis. The present study reports on the chemical synthesis and biological evaluation of wat
Autor:
Takato Kagami, Nakahara Makiko, Shigeru Kinoshita, Keita Fujii, Naoki Okumura, Noriko Koizumi, Miu Kitahara
Publikováno v:
Investigative ophthalmologyvisual science. 57(15)
Purpose Rho kinase (ROCK) pathways control fundamental cell functions, making ROCK an important therapeutic target in several pathophysiologic conditions. The purpose of this study was to investigate whether inhibition of ROCK can suppress apoptosis
Effect of a p38 Mitogen-Activated Protein Kinase Inhibitor on Corneal Endothelial Cell Proliferation
Publikováno v:
Investigative Opthalmology & Visual Science. 59:4218
Purpose We have performed clinical research on cell-based therapy for corneal endothelial decompensation since 2013. The purpose of this study was to investigate the usefulness of a p38 MAPK inhibitor for promoting proliferation of human corneal endo
Autor:
Daiki Matsumoto, Kazuya Kakutani, Ryota Inoue, Naoki Okumura, Tomoki Shimada, Makiko Nakahara, Yumiko Kiyanagi, Takehiro Itoh, Noriko Koizumi
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0158427 (2016)
PLoS ONE
PLoS ONE
The corneal endothelium maintains corneal transparency by its pump and barrier functions; consequently, its decompensation due to any pathological reason causes severe vision loss due to corneal haziness. Corneal transplantation is the only therapeut
Autor:
Hideaki Tsuchiya, Naoki Okumura, Hiroaki Takahashi, Noriko Koizumi, Shigeru Kinoshita, Junji Hamuro, Yuji Sakamoto, Morio Ueno
Publikováno v:
The American Journal of Pathology. 181:268-277
Corneal endothelial dysfunction accompanied by visual disturbance is a primary indication for corneal transplantation. We previously reported that the adhesion of corneal endothelial cells (CECs) to a substrate was enhanced by the selective ROCK inhi
Autor:
Ayaka Kusakabe, Hiroatsu Hirano, Shigeru Kinoshita, Yugo Okazaki, Ryota Inoue, Shinichiro Nakano, Naoki Okumura, Noriko Koizumi
Publikováno v:
Scientific Reports
The corneal endothelium is essential for maintaining corneal transparency; therefore, corneal endothelial dysfunction causes serious vision loss. Tissue engineering-based therapy is potentially a less invasive and more effective therapeutic modality.