Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Matthew R. Sydes"'
Autor:
Annabelle South, Claire Snowdon, Eva Burnett, Barbara E. Bierer, Katie Gillies, Talia Isaacs, Matthew R. Sydes
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-18 (2024)
Abstract Background Sharing trial results with participants is a moral imperative, but too often does not happen in appropriate ways. Methods We carried out semi-structured interviews with patients (n = 13) and site staff (n = 11), and surveyed 180 p
Externí odkaz:
https://doaj.org/article/4821c719f2054037b6d8620aa4304957
Autor:
Martin Law, Dominique-Laurent Couturier, Babak Choodari-Oskooei, Phillip Crout, Carrol Gamble, Peter Jacko, Philip Pallmann, Mark Pilling, David S. Robertson, Michael Robling, Matthew R. Sydes, Sofía S. Villar, James Wason, Graham Wheeler, S. Faye Williamson, Christina Yap, Thomas Jaki
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-5 (2023)
Abstract In the UK, the Medicines and Healthcare products Regulatory Agency consulted on proposals “to improve and strengthen the UK clinical trials legislation to help us make the UK the best place to research and develop safe and innovative medic
Externí odkaz:
https://doaj.org/article/b3bab057419146f7a2a0ab4aaefdc771
Autor:
Adam D. N. Williams, Gwyneth Davies, Amanda J. Farrin, Marion Mafham, Michael Robling, Matthew R. Sydes, Fiona V. Lugg-Widger
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-8 (2023)
Abstract Background Researchers are increasingly seeking to use routinely collected data to support clinical trials. This approach has the potential to transform the way clinical trials are conducted in the future. The availability of routinely colle
Externí odkaz:
https://doaj.org/article/bf008c8250a44052b9664a1523c56ef3
Autor:
Martin Law, Dominique-Laurent Couturier, Babak Choodari-Oskooei, Phillip Crout, Carrol Gamble, Peter Jacko, Philip Pallmann, Mark Pilling, David S. Robertson, Michael Robling, Matthew R. Sydes, Sofía S. Villar, James Wason, Graham Wheeler, S. Faye Williamson, Christina Yap, Thomas Jaki
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/40c2eed3118c4c9da008c2e610d68b01
Autor:
Sharon B. Love, Fay Cafferty, Claire Snowdon, Karen Carty, Joshua Savage, Philip Pallmann, Lucy McParland, Louise Brown, Lindsey Masters, Francesca Schiavone, Dominic Hague, Stephen Townsend, Claire Amos, Annabelle South, Kate Sturgeon, Ruth Langley, Timothy Maughan, Nicholas James, Emma Hall, Sarah Kernaghan, Judith Bliss, Nick Turner, Andrew Tutt, Christina Yap, Charlotte Firth, Anthony Kong, Hisham Mehanna, Colin Watts, Robert Hills, Ian Thomas, Mhairi Copland, Sue Bell, David Sebag-Montefiore, Robert Jones, Mahesh K. B. Parmar, Matthew R. Sydes
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-14 (2022)
Abstract Background Late-phase platform protocols (including basket, umbrella, multi-arm multi-stage (MAMS), and master protocols) are generally agreed to be more efficient than traditional two-arm clinical trial designs but are not extensively used.
Externí odkaz:
https://doaj.org/article/f16f51eff76c45b9b2545597e35df8a3
Autor:
Sharon B. Love, Anna Kilanowski, Victoria Yorke-Edwards, Oliver Old, Hugh Barr, Clive Stokes, Catherine Kendall, Matthew R. Sydes
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-10 (2021)
Abstract Background A promising approach to reduce the increasing costs of clinical trials is the use of routinely collected health data as participant data. However, the quality of this data could limit its usability as trial participant data. Metho
Externí odkaz:
https://doaj.org/article/0a8fa781707340eea88e815fe70ca485
Autor:
Emily Day, A. Toby Prevost, Matthew R. Sydes, Deepika Reddy, Taimur T. Shah, Mathias Winkler, Tim Dudderidge, John Staffurth, Stuart McCracken, Vincent Khoo, Puja Jadav, Natalia Klimowska-Nassar, Thiagarajah Sasikaran, Hashim U. Ahmed, Francesca Fiorentino
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-12 (2021)
Abstract Background Randomised controlled trials (RCTs) for surgical interventions have often proven difficult with calls for innovative approaches. The Imperial Prostate (IP4) Comparative Health Research Outcomes of Novel Surgery in prostate cancer
Externí odkaz:
https://doaj.org/article/852ed8f3f23e4607b9359eacd6bd00ac
Autor:
Archie Macnair, Sharon B. Love, Macey L. Murray, Duncan C. Gilbert, Mahesh K. B. Parmar, Tom Denwood, James Carpenter, Matthew R. Sydes, Ruth E. Langley, Fay H. Cafferty
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-10 (2021)
Abstract Background Routinely collected electronic health records (EHRs) have the potential to enhance randomised controlled trials (RCTs) by facilitating recruitment and follow-up. Despite this, current EHR use is minimal in UK RCTs, in part due to
Externí odkaz:
https://doaj.org/article/b1921d19946446b7802947c78af104a7
Autor:
Hussein Ibrahim, Xiaoxuan Liu, Samantha Cruz Rivera, David Moher, An-Wen Chan, Matthew R. Sydes, Melanie J. Calvert, Alastair K. Denniston
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-5 (2021)
Abstract Background The application of artificial intelligence (AI) in healthcare is an area of immense interest. The high profile of ‘AI in health’ means that there are unusually strong drivers to accelerate the introduction and implementation o
Externí odkaz:
https://doaj.org/article/5768b33cd0664f9e8695072e1ad62d0e
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-8 (2020)
Abstract Background Safety data is required to be collected in all clinical trials and can be separated into two types of data, adverse events and serious adverse events. Often, these types of safety data are collected as two discrete data sets, wher
Externí odkaz:
https://doaj.org/article/94d37ab855b24cdf9c9c03a64e5de89c