Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sarah Williams-Blangero"'
Autor:
Juan M. Peralta, Sandra Laston, Janardan Subedi, John Blangero, Suman S Thapa, Satish Kumar, Matthew P. Johnson, Nicholas B. Blackburn, Bradford Towne, Sarah Williams-Blangero, Ryan Keyho
Publikováno v:
Journal of Diabetes Research
Journal of Diabetes Research, Vol 2019 (2019)
Journal of Diabetes Research, Vol 2019 (2019)
Measurements of fasting glucose (FG) or glycated hemoglobin A1c (HbA1c) are two clinically approved approaches commonly used to determine glycemia, both of which are influenced by genetic factors. Obtaining accurate measurements of FG or HbA1c is not
Autor:
Anthony G. Comuzzie, Satish Kumar, Matthew P. Johnson, Eric K. Moses, Marcio Almeida, Angela K Dean, Donna M. Lehman, Sarah Williams-Blangero, Melanie A. Carless, Joanne E. Curran, August Blackburn, Harald H H Göring, Lawrence J. Abraham, Thomas D. Dyer, John Blangero, Michael C. Mahaney, Laura Almasy
Publikováno v:
European Journal of Human Genetics
Only few systematic studies on the contribution of copy number variation to gene expression variation have been published to date. Here we identify effects of copy number variable regions (CNVRs) on nearby gene expression by investigating 909 CNVRs a
Autor:
Thomas D. Dyer, Janardan Subedi, Bharat Jha, John L. VandeBerg, Sarah Williams-Blangero, John Blangero, Bradford Towne, Kimberly D. Williams
Publikováno v:
American Journal of Human Biology. 25:743-750
Objectives There is phenotypic overlap between Brachydactyly Type D (BDD) and Brachydactyly Type E (BDE) that suggests a possible common underlying etiology. We seek to understand the genetic underpinnings of, and relationship between, these skeletal
Autor:
Sarah Williams-Blangero, Ravindranath Duggirala, Hemant Kulkarni, Michael C. Mahaney, Juan M. Peralta, Manju Mamtani, Laura Almasy, Harald H H Göring, Vincent Diego, Joanne E. Curran, Thomas D. Dyer, John Blangero
Publikováno v:
Journal of Diabetes Research, Vol 2016 (2016)
SLC30A8encodes zinc transporter 8 which is involved in packaging and release of insulin. Evidence for the association ofSLC30A8variants with type 2 diabetes (T2D) is inconclusive. We interrogated single nucleotide polymorphisms (SNPs) aroundSLC30A8fo
Autor:
Sarah Williams-Blangero, John L. VandeBerg, Rodrigo Correa-Oliveira, Janardan Subedi, Bharat Jha, John Blangero
Publikováno v:
The Journal of Infectious Diseases. 197:66-71
A linkage-based genome scan of 1258 members of a single pedigree of the Jirel population of Nepal localized 6 potential quantitative trait loci (QTLs) influencing susceptibility to infection with Ascaris lumbricoides Ascaris lumbricoides, the most co
Publikováno v:
Genetic Epidemiology. 10:617-622
A major locus influencing apolipoprotein AI (apo AI) serum levels was detected using data from the Donner Laboratory Family Study. This locus accounts for 46% of the phenotypic variability in apo AI levels. Multivariate segregation analysis revealed
Publikováno v:
American Journal of Primatology. 27:119-132
Recent progress in molecular and biochemical genetics has led to the identification of numerous polymorphic candidate genes likely to be important in the determination of quantitative variation in physiological processes. In this paper, we review a s
Autor:
Sarah Williams-Blangero, John Blangero
Publikováno v:
Human biology. 78(1)
Pedigree data are useful for a wealth of research purposes in human population biology and genetics. The collection of extended pedigrees represents the most powerful sampling design for quantitative genetic and linkage studies of both normal and dis
Autor:
Sarah Williams-Blangero, John L. VandeBerg, John Blangero, Janardan Subedi, Dev R. Rai, Ram Prasad Upadhayay, Bharat Jha, Mary Jo Aivaliotis
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 99(8)
Nematode parasites show a characteristic aggregated distribution among hosts. This observation has important implications for pathogenesis, immunology, and control of these infections, but the relative roles of environment and genetics in determining