Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Johnson, Andrew D"'
Autor:
Mikhaylova AV; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA., McHugh CP; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA., Polfus LM; Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA., Raffield LM; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Boorgula MP; Division of Biomedical Informatics and Personalized Medicine, School of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA., Blackwell TW; TOPMed Informatics Research Center, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98105, USA., Broome J; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA., Chami N; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York City, NY 10029, USA., Chen MH; Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Bethesda, MD 20892, USA; National Heart, Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA 01701, USA., Conomos MP; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA., Cox C; Division of Biomedical Informatics and Personalized Medicine, School of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA., Curran JE; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX 78539, USA., Daya M; Division of Biomedical Informatics and Personalized Medicine, School of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA., Ekunwe L; Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA., Glahn DC; Department of Psychiatry, Boston Children's Hospital and Harvard Medical School, Boston, MA 02155, USA., Heard-Costa N; National Heart, Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA 01701, USA; Department of Neurology, Boston University School of Medicine, Boston, MA 02118, USA., Highland HM; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Hobbs BD; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA., Ilboudo Y; Montréal Heart Institute, Montréal, Québec H1T 1C8, Canada; Faculté de Médecine, Université de Montréal, Montréal, Québec H1T 1C8, Canada., Jain D; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA., Lange LA; Division of Biomedical Informatics and Personalized Medicine, School of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA., Miller-Fleming TW; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37240, USA., Min N; Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA., Moon JY; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA., Preuss MH; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York City, NY 10029, USA., Rosen J; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Ryan K; Department of Medicine, Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Smith AV; TOPMed Informatics Research Center, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA., Sun Q; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Surendran P; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge CB1 8RN, UK; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge CB1 8RN, UK; Rutherford Fund Fellow, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., de Vries PS; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Walter K; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK., Wang Z; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York City, NY 10029, USA., Wheeler M; Department of Genome Sciences, University of Washington, Seattle, WA 98105, USA., Yanek LR; Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Zhong X; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37240, USA., Abecasis GR; TOPMed Informatics Research Center, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA., Almasy L; Department of Biomedical and Health Informatics, the Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA., Barnes KC; Division of Biomedical Informatics and Personalized Medicine, School of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA., Beaty TH; School of Public Health, John Hopkins University, Baltimore, MD 21205, USA., Becker LC; Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Blangero J; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX 78539, USA., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Butterworth AS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge CB1 8RN, UK; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge CB1 8RN, UK; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge CB1 8RN, UK; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge CB1 8RN, UK., Chavan S; Division of Biomedical Informatics and Personalized Medicine, School of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA., Cho MH; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA., Choquet H; Division of Research, Kaiser Permanente Northern California, Oakland, CA 94601, USA., Correa A; Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA., Cox N; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37240, USA., DeMeo DL; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA., Faraday N; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Fornage M; University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Gerszten RE; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Hou L; Institute for Public Health and Medicine, Northwestern University, Chicago, IL 60661, USA., Johnson AD; Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Bethesda, MD 20892, USA; National Heart, Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA 01701, USA., Jorgenson E; Regeneron Genetics Center, Tarrytown, NY 10591, USA., Kaplan R; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA., Kooperberg C; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA., Kundu K; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK; Department of Haematology, University of Cambridge, Cambridge CB1 8RN, UK., Laurie CA; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA., Lettre G; Montréal Heart Institute, Montréal, Québec H1T 1C8, Canada; Faculté de Médecine, Université de Montréal, Montréal, Québec H1T 1C8, Canada., Lewis JP; Department of Medicine, Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Li B; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232, USA., Li Y; Departments of Biostatistics, Genetics, and Computer Science, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Lloyd-Jones DM; Division of Cardiology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60661, USA; Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60661, USA., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York City, NY 10029, USA., Manichaikul A; Center for Public Health Genomics, Department of Public Health Sciences, University of Virginia School of Medicine, Charlottesville, VA 22908, USA., Meyers DA; Division of Genetics, Genomics and Precision Medicine, Department of Medicine, University of Arizona, Tucson, AZ 85724, USA., Mitchell BD; Department of Medicine, Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD 21201, USA; Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, MD 21201, USA., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Ngo D; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Nickerson DA; Department of Genome Sciences, University of Washington, Seattle, WA 98105, USA., Nongmaithem S; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK., North KE; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., O'Connell JR; Department of Medicine, Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Ortega VE; Department of Internal Medicine, Center for Precision Medicine, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA., Pankratz N; Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, MN 55455, USA., Perry JA; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Psaty BM; Department of Epidemiology, University of Washington, Seattle, WA 98105, USA; Department of Health Service, University of Washington, Seattle, WA 98105, USA; Department of Medicine, University of Washington, Seattle, WA 98105, USA., Rich SS; Center for Public Health Genomics, Department of Public Health Sciences, University of Virginia School of Medicine, Charlottesville, VA 22908, USA., Soranzo N; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge CB1 8RN, UK; Department of Haematology, University of Cambridge, Cambridge CB1 8RN, UK; British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Cambridge CB1 8RN, UK., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Silverman EK; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA., Smith NL; Department of Epidemiology, University of Washington, Seattle, WA 98105, USA; Department of Health Service, University of Washington, Seattle, WA 98105, USA; Seattle Epidemiologic Research and Information Center, Department of Veterans Affairs Office of Research and Development, Seattle, WA 98105, USA., Tang H; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA., Tracy RP; Department of Pathology and Laboratory Medicine and Department of Biochemistry, University of Vermont Larner College of Medicine, Colchester, VT 05446, USA., Thornton TA; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA; Regeneron Genetics Center, Tarrytown, NY 10591, USA., Vasan RS; National Heart, Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA 01701, USA; Departments of Cardiology and Preventive Medicine, Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA; Department of Epidemiology, Boston University School of Public Health, Boston, MA 02118, USA., Zein J; Respiratory Institute, Cleveland Clinic, Cleveland, OH 44195, USA., Mathias RA; Division of Allergy and Clinical Immunology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Reiner AP; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA. Electronic address: apreiner@uw.edu., Auer PL; Zilber School of Public Health, University of Wisconsin, Milwaukee, Milwaukee, WI 53205, USA. Electronic address: pauer@mcw.edu.
Publikováno v:
American journal of human genetics [Am J Hum Genet] 2021 Oct 07; Vol. 108 (10), pp. 1836-1851. Date of Electronic Publication: 2021 Sep 27.
Autor:
Huan T; The Framingham Heart Study, Framingham, MA, USA. tianxiao.huan@nih.gov.; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA. tianxiao.huan@nih.gov., Joehanes R; The Framingham Heart Study, Framingham, MA, USA.; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Song C; The Framingham Heart Study, Framingham, MA, USA.; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.; Department of Medical Sciences, Uppsala University, Uppsala, Sweden.; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Peng F; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Guo Y; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA., Mendelson M; The Framingham Heart Study, Framingham, MA, USA.; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.; Department of Cardiology, Boston Children's Hospital, Harvard University, Boston, MA, USA., Yao C; The Framingham Heart Study, Framingham, MA, USA.; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Liu C; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Ma J; The Framingham Heart Study, Framingham, MA, USA.; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Richard M; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Agha G; Mailman School of Public Health, Columbia University, New York City, NY, USA., Guan W; Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Almli LM; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA., Conneely KN; Department of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA., Keefe J; The Framingham Heart Study, Framingham, MA, USA.; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Hwang SJ; The Framingham Heart Study, Framingham, MA, USA.; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Johnson AD; The Framingham Heart Study, Framingham, MA, USA.; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Fornage M; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Liang L; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA. lliang@hsph.harvard.edu.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA. lliang@hsph.harvard.edu., Levy D; The Framingham Heart Study, Framingham, MA, USA. Levyd@nih.gov.; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA. Levyd@nih.gov.
Publikováno v:
Nature communications [Nat Commun] 2019 Sep 19; Vol. 10 (1), pp. 4267. Date of Electronic Publication: 2019 Sep 19.
Autor:
Evangelou E; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Warren HR; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research, Barts Cardiovascular Biomedical Research Center, Queen Mary University of London, London, UK., Mosen-Ansorena D; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Mifsud B; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Pazoki R; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Gao H; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK., Ntritsos G; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Dimou N; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Cabrera CP; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research, Barts Cardiovascular Biomedical Research Center, Queen Mary University of London, London, UK., Karaman I; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Ng FL; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Evangelou M; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Mathematics, Imperial College London, London, UK., Witkowska K; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Tzanis E; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Hellwege JN; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Giri A; Vanderbilt Genetics Institute, Vanderbilt Epidemiology Center, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center; Tennessee Valley Health Systems VA, Nashville, TN, USA., Velez Edwards DR; Vanderbilt Genetics Institute, Vanderbilt Epidemiology Center, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center; Tennessee Valley Health Systems VA, Nashville, TN, USA., Sun YV; Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA, USA.; Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA, USA., Cho K; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA, USA.; Division of Aging, Department of Medicine, Brigham and Women's Hospital; Department of Medicine, Harvard Medical School, Boston, MA, USA., Gaziano JM; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA, USA.; Division of Aging, Department of Medicine, Brigham and Women's Hospital; Department of Medicine, Harvard Medical School, Boston, MA, USA., Wilson PWF; Atlanta VAMC and Emory Clinical Cardiovascular Research Institute, Atlanta, GA, USA., Tsao PS; VA Palo Alto Health Care System, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA., Kovesdy CP; Nephrology Section, Memphis VA Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA., Esko T; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA., Mägi R; Estonian Genome Center, University of Tartu, Tartu, Estonia., Milani L; Estonian Genome Center, University of Tartu, Tartu, Estonia., Almgren P; Department Clinical Sciences, Malmö, Lund University, Malmö, Sweden., Boutin T; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Debette S; Department of Neurology, Bordeaux University Hospital, Bordeaux, France.; Univ. Bordeaux, Inserm, Bordeaux Population Health Research Center, CHU Bordeaux, Bordeaux, France., Ding J; Laboratory of Genetics and Genomics, NIA/NIH, Baltimore, MD, USA., Giulianini F; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA., Holliday EG; Hunter Medical Research Institute and Faculty of Health, University of Newcastle, New Lambton Heights, New South Wales, Australia., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Li-Gao R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Lin WY; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Mangino M; Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK.; NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust, London, UK., Oldmeadow C; Hunter Medical Research Institute and Faculty of Health, University of Newcastle, New Lambton Heights, New South Wales, Australia., Prins BP; Wellcome Trust Sanger Institute, Hinxton, UK., Qian Y; Laboratory of Genetics and Genomics, NIA/NIH, Baltimore, MD, USA., Sargurupremraj M; Univ. Bordeaux, Inserm, Bordeaux Population Health Research Center, CHU Bordeaux, Bordeaux, France., Shah N; Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, UK.; Department of Pharmacy, COMSATS Institute of Information Technology, Abbottabad, Pakistan., Surendran P; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Thériault S; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.; Institut universitaire de cardiologie et de pneumologie de Québec-Université Laval, Quebec City, Quebec, Canada., Verweij N; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA.; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, the Netherlands., Willems SM; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Zhao JH; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Amouyel P; University of Lille, Inserm, Centre Hosp. Univ. Lille, Institut Pasteur de Lille, UMR1167 - RID-AGE - Risk factors and molecular determinants of aging-related diseases, Epidemiology and Public Health Department, Lille, France., Connell J; University of Dundee, Ninewells Hospital & Medical School, Dundee, UK., de Mutsert R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Doney ASF; Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, UK., Farrall M; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Menni C; Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK., Morris AD; Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Noordam R; Department of Internal Medicine, Section Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands., Paré G; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada., Poulter NR; Imperial Clinical Trials Unit, London, UK., Shields DC; School of Medicine, University College Dublin, Dublin, Ireland., Stanton A; Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland., Thom S; International Centre for Circulatory Health, Imperial College London, London, UK., Abecasis G; Center for Statistical Genetics, Department of Biostatistics, SPH II, Washington Heights, Ann Arbor, MI, USA., Amin N; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands., Arking DE; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Ayers KL; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.; Sema4, a Mount Sinai venture, Stamford, CT, USA., Barbieri CM; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy., Batini C; Department of Health Sciences, University of Leicester, Leicester, UK., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Blake T; Department of Health Sciences, University of Leicester, Leicester, UK., Bochud M; Institute of Social and Preventive Medicine, University Hospital of Lausanne, Lausanne, Switzerland., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Boerwinkle E; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston and Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Boomsma DI; Department of Biological Psychology, Vrije Universiteit Amsterdam, EMGO+ Institute, VU University Medical Center, Amsterdam, the Netherlands., Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Braund PS; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Brumat M; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy., Campbell A; Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK., Campbell H; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK., Chakravarti A; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Department of Cardiology, Ealing Hospital, Middlesex, UK.; Imperial College Healthcare NHS Trust, London, UK., Chauhan G; Centre for Brain Research, Indian Institute of Science, Bangalore, India., Ciullo M; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Napoli, Italy.; IRCCS Neuromed, Pozzilli, Isernia, Italy., Cocca M; Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy., Collins F; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, MD, USA., Cordell HJ; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK., Davies G; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., de Borst MH; Department of Internal Medicine, Division of Nephrology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., de Geus EJ; Department of Biological Psychology, Vrije Universiteit Amsterdam, EMGO+ Institute, VU University Medical Center, Amsterdam, the Netherlands., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Deelen J; Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Del Greco M F; Institute for Biomedicine, Eurac Research, Bolzano, Italy - Affiliated Institute of the University of Lübeck, Lübeck, Germany., Demirkale CY; Mathematical and Statistical Computing Laboratory, Office of Intramural Research, Center for Information Technology, National Institutes of Health, Bethesda, MD, USA., Dörr M; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Ehret GB; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Cardiology, Department of Medicine, Geneva University Hospital, Geneva, Switzerland., Elosua R; CIBERCV & Cardiovascular Epidemiology and Genetics, IMIM, Barcelona, Spain.; Faculty of Medicine, Universitat de Vic-Central de Catalunya, Vic, Spain., Enroth S; Department of Immunology, Genetics and Pathology, Uppsala Universitet, Science for Life Laboratory, Uppsala, Sweden., Erzurumluoglu AM; Department of Health Sciences, University of Leicester, Leicester, UK., Ferreira T; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Big Data Institute, Li Ka Shing Center for Health for Health Information and Discovery, Oxford University, Oxford, UK., Frånberg M; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Centre for Molecular Medicine, L8:03, Karolinska Universitetsjukhuset, Solna, Sweden.; Department of Numerical Analysis and Computer Science, Stockholm University, Stockholm, Sweden., Franco OH; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands., Gandin I; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy., Gasparini P; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy., Giedraitis V; Department of Public Health and Caring Sciences, Geriatrics, Uppsala, Sweden., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany., Girotto G; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy., Goel A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Gow AJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, School of Social Sciences, Heriot-Watt University, Edinburgh, UK., Gudnason V; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Icelandic Heart Association, Kopavogur, Iceland., Guo X; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Gyllensten U; Department of Immunology, Genetics and Pathology, Uppsala Universitet, Science for Life Laboratory, Uppsala, Sweden., Hamsten A; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Centre for Molecular Medicine, L8:03, Karolinska Universitetsjukhuset, Solna, Sweden., Harris TB; Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, MD, USA., Harris SE; Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Hartman CA; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Havulinna AS; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Hicks AA; Institute for Biomedicine, Eurac Research, Bolzano, Italy - Affiliated Institute of the University of Lübeck, Lübeck, Germany., Hofer E; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria.; Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria., Hofman A; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Hottenga JJ; Department of Biological Psychology, Vrije Universiteit Amsterdam, EMGO+ Institute, VU University Medical Center, Amsterdam, the Netherlands., Huffman JE; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK.; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; The Population Science Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Hwang SJ; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; The Population Science Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Ingelsson E; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., James A; Department of Pulmonary Physiology and Sleep, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, Western Australia, Australia.; School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia., Jansen R; Department of Psychiatry, VU University Medical Center, Amsterdam Neuroscience, Amsterdam, the Netherlands., Jarvelin MR; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Center For Life-course Health Research, University of Oulu, Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, Oulu, Oulu, Finland., Joehanes R; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; Hebrew SeniorLife, Harvard Medical School, Boston, MA, USA., Johansson Å; Department of Immunology, Genetics and Pathology, Uppsala Universitet, Science for Life Laboratory, Uppsala, Sweden., Johnson AD; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Joshi PK; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK., Jousilahti P; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands., Jula A; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland.; Department of Clinical Physiology, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Kathiresan S; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA.; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA., Keavney BD; Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Division of Medicine, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Khaw KT; Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Cambridge, UK., Knekt P; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland., Knight J; Data Science Institute and Lancaster Medical School, Lancaster, UK., Kolcic I; Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia., Kooner JS; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK.; Imperial College Healthcare NHS Trust, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK., Koskinen S; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland., Kristiansson K; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland., Kutalik Z; Institute of Social and Preventive Medicine, University Hospital of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Laan M; Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia., Larson M; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA., Launer LJ; Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, MD, USA., Lehne B; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Liewald DCM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Lin L; Cardiology, Department of Medicine, Geneva University Hospital, Geneva, Switzerland., Lind L; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden., Lindgren CM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Big Data Institute, Li Ka Shing Center for Health for Health Information and Discovery, Oxford University, Oxford, UK.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA., Liu Y; Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA., Loos RJF; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Mindich Child Health Development Institute, The Icahn School of Medicine at Mount Sinai, New York, NY, USA., Lopez LM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin, Ireland.; University College Dublin, UCD Conway Institute, Centre for Proteome Research, UCD, Belfield, Dublin, Ireland., Lu Y; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Mamasoula C; Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK., Marrugat J; CIBERCV & Cardiovascular Epidemiology and Genetics, IMIM, Barcelona, Spain., Marten J; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Milaneschi Y; Department of Psychiatry, Amsterdam Public Health and Amsterdam Neuroscience, VU University Medical Center/GGZ inGeest, Amsterdam, the Netherlands., Morgan A; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy., Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Biostatistics, University of Liverpool, Liverpool, UK., Morrison AC; Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., Munson PJ; Mathematical and Statistical Computing Laboratory, Office of Intramural Research, Center for Information Technology, National Institutes of Health, Bethesda, MD, USA., Nalls MA; Data Tecnica International, Glen Echo, MD, USA.; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, USA., Nandakumar P; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Niiranen T; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland.; Department of Medicine, Turku University Hospital and University of Turku, Turku, Finland., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Nutile T; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Napoli, Italy., Oldehinkel AJ; Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Oostra BA; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands., O'Reilly PF; SGDP Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Org E; Estonian Genome Center, University of Tartu, Tartu, Estonia., Padmanabhan S; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK.; British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Palmas W; Department of Medicine, Columbia University Medical Center, New York, NY, USA., Palotie A; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Analytic and Translational Genetics Unit, Department of Medicine, Department of Neurology and Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; The Stanley Center for Psychiatric Research and Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Pattie A; Department of Psychology, University of Edinburgh, Edinburgh, UK., Penninx BWJH; Department of Psychiatry, Amsterdam Public Health and Amsterdam Neuroscience, VU University Medical Center/GGZ inGeest, Amsterdam, the Netherlands., Perola M; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; University of Tartu, Tartu, Estonia., Peters A; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.; German Center for Cardiovascular Disease Research (DZHK), partner site Munich, Neuherberg, Germany., Polasek O; Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia.; Psychiatric Hospital 'Sveti Ivan', Zagreb, Croatia., Pramstaller PP; Institute for Biomedicine, Eurac Research, Bolzano, Italy - Affiliated Institute of the University of Lübeck, Lübeck, Germany.; Department of Neurology, General Central Hospital, Bolzano, Italy.; Department of Neurology, University of Lübeck, Lübeck, Germany., Nguyen QT; Mathematical and Statistical Computing Laboratory, Office of Intramural Research, Center for Information Technology, National Institutes of Health, Bethesda, MD, USA., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Ren M; Fujian Key Laboratory of Geriatrics, Department of Geriatric Medicine, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, China., Rettig R; Institute of Physiology, University Medicine Greifswald, Karlsburg, Germany., Rice K; Department of Biostatistics, University of Washington, Seattle, WA, USA., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Ried JS; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Riese H; Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Ripatti S; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Robino A; Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy., Rose LM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK., Ruggiero D; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Napoli, Italy.; IRCCS Neuromed, Pozzilli, Isernia, Italy., Saba Y; Gottfried Schatz Research Center for Cell Signaling, Metabolism & Aging, Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria., Sala CF; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy., Salomaa V; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Sarin AP; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Schmidt R; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria., Schmidt H; Gottfried Schatz Research Center for Cell Signaling, Metabolism & Aging, Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria., Shrine N; Department of Health Sciences, University of Leicester, Leicester, UK., Siscovick D; The New York Academy of Medicine, New York, NY, USA., Smith AV; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Icelandic Heart Association, Kopavogur, Iceland., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Sõber S; Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia., Sorice R; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Napoli, Italy., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK., Stott DJ; Institute of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow, UK., Strachan DP; Population Health Research Institute, St George's, University of London, London, UK., Strawbridge RJ; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Centre for Molecular Medicine, L8:03, Karolinska Universitetsjukhuset, Solna, Sweden., Sundström J; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden., Swertz MA; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Taylor KD; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Teumer A; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Tobin MD; Department of Health Sciences, University of Leicester, Leicester, UK., Tomaszewski M; Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Division of Medicine, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Toniolo D; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy., Traglia M; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands., Tuomilehto J; Dasman Diabetes Institute, Dasman, Kuwait.; Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Saudi Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Tzourio C; Univ. Bordeaux, Inserm, Bordeaux Population Health Research Center, CHU Bordeaux, Bordeaux, France., Uitterlinden AG; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus MC, Rotterdam, the Netherlands., Vaez A; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., van Duijn CM; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands., Vergnaud AC; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Verwoert GC; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands., Vitart V; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Völker U; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Vollenweider P; Department of Internal Medicine, University Hospital, CHUV, Lausanne, Switzerland., Vuckovic D; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.; Experimental Genetics Division, Sidra Medical and Research Center, Doha, Qatar., Watkins H; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Wild SH; Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK., Willemsen G; Department of Biological Psychology, Vrije Universiteit Amsterdam, EMGO+ Institute, VU University Medical Center, Amsterdam, the Netherlands., Wilson JF; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK.; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK., Wright AF; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Yao J; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Zemunik T; Department of Biology, Faculty of Medicine, University of Split, Split, Croatia., Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK., Attia JR; Hunter Medical Research Institute and Faculty of Health, University of Newcastle, New Lambton Heights, New South Wales, Australia., Butterworth AS; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; The National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Conen D; Division of Cardiology, University Hospital, Basel, Switzerland.; Division of Cardiology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada., Cucca F; Institute of Genetic and Biomedical Research, National Research Council (CNR), Monserrato, Cagliari, Italy.; Department of Biomedical Sciences, University of Sassari, Sassari, Italy., Danesh J; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; The National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK., Hayward C; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Howson JMM; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Lakatta EG; Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Melander O; Department Clinical Sciences, Malmö, Lund University, Malmö, Sweden., Mook-Kanamori DO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands., Palmer CNA; Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, UK., Risch L; Labormedizinisches Zentrum Dr. Risch, Schaan, Liechtenstein.; Private University of the Principality of Liechtenstein, Triesen, Liechtenstein.; University Institute of Clinical Chemistry, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Scott RA; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Scott RJ; Hunter Medical Research Institute and Faculty of Health, University of Newcastle, New Lambton Heights, New South Wales, Australia., Sever P; National Heart and Lung Institute, Imperial College London, London, UK., Spector TD; Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK., van der Harst P; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Zeggini E; Wellcome Trust Sanger Institute, Hinxton, UK., Levy D; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Munroe PB; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research, Barts Cardiovascular Biomedical Research Center, Queen Mary University of London, London, UK., Newton-Cheh C; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA., Brown MJ; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research, Barts Cardiovascular Biomedical Research Center, Queen Mary University of London, London, UK., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia., Hung AM; Tennessee Valley Healthcare System (Nashville VA) & Vanderbilt University, Nashville, TN, USA., O'Donnell CJ; VA Boston Healthcare, Section of Cardiology and Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Edwards TL; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Psaty BM; Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology and Health Services, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA., Tzoulaki I; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK., Barnes MR; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research, Barts Cardiovascular Biomedical Research Center, Queen Mary University of London, London, UK., Wain LV; Department of Health Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Elliott P; Department of Epidemiology and Biostatistics, Imperial College London, London, UK. p.elliott@imperial.ac.uk.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK. p.elliott@imperial.ac.uk.; National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare NHS Trust and Imperial College London, London, UK. p.elliott@imperial.ac.uk.; UK Dementia Research Institute (UK DRI) at Imperial College London, London, UK. p.elliott@imperial.ac.uk.; Health Data Research-UK London substantive site, London, UK. p.elliott@imperial.ac.uk., Caulfield MJ; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. m.j.caulfield@qmul.ac.uk.; National Institute for Health Research, Barts Cardiovascular Biomedical Research Center, Queen Mary University of London, London, UK. m.j.caulfield@qmul.ac.uk.
Publikováno v:
Nature genetics [Nat Genet] 2018 Oct; Vol. 50 (10), pp. 1412-1425. Date of Electronic Publication: 2018 Sep 17.
Autor:
Yao C; Framingham Heart Study, Framingham, 01702, MA, USA.; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, 20892, MD, USA., Chen G; Framingham Heart Study, Framingham, 01702, MA, USA.; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, 20892, MD, USA., Song C; Framingham Heart Study, Framingham, 01702, MA, USA.; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, 20892, MD, USA.; Department of Medical Sciences, Uppsala University, 75105, Uppsala, Sweden.; Department of Immunology, Genetics and Pathology, Uppsala University, 75105, Uppsala, Sweden., Keefe J; Framingham Heart Study, Framingham, 01702, MA, USA.; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, 20892, MD, USA., Mendelson M; Framingham Heart Study, Framingham, 01702, MA, USA.; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, 20892, MD, USA.; Department of Cardiology, Boston Children's Hospital, Boston, 02115, MA, USA., Huan T; Framingham Heart Study, Framingham, 01702, MA, USA.; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, 20892, MD, USA., Sun BB; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Laser A; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany., Maranville JC; MRL, Merck & Co., Inc, Kenilworth, 07033, NJ, USA., Wu H; Computer Science and Networking, Wentworth Institute of Technology, Boston, 02115, MA, USA., Ho JE; Cardiovascular Research Center and Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Boston, 02114, MA, USA., Courchesne P; Framingham Heart Study, Framingham, 01702, MA, USA.; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, 20892, MD, USA., Lyass A; Framingham Heart Study, Framingham, 01702, MA, USA.; Department of Mathematics and Statistics, Boston University, Boston, 02115, MA, USA., Larson MG; Framingham Heart Study, Framingham, 01702, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, 02118, MA, USA., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Ingolstädter Landstraße 1, 85764, Neuherberg, Germany., Graumann J; Scientific Service Group Biomolecular Mass Spectrometry, Max Planck Institute for Heart and Lung Research, W.G. Kerckhoff Institute, Ludwigstr. 43, D-61231, Bad Nauheim, Germany., Johnson AD; Framingham Heart Study, Framingham, 01702, MA, USA.; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, 20892, MD, USA., Danesh J; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.; British Heart Foundation Cambridge Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK.; Department of Human Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1RQ, UK., Runz H; MRL, Merck & Co., Inc, Kenilworth, 07033, NJ, USA., Hwang SJ; Framingham Heart Study, Framingham, 01702, MA, USA.; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, 20892, MD, USA., Liu C; Framingham Heart Study, Framingham, 01702, MA, USA.; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, 20892, MD, USA., Butterworth AS; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Suhre K; Department of Physiology and Biophysics, Weill Cornell Medicine-Qatar, Education City, PO 24144, Doha, Qatar., Levy D; Framingham Heart Study, Framingham, 01702, MA, USA. levyd@nih.gov.; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, 20892, MD, USA. levyd@nih.gov.
Publikováno v:
Nature communications [Nat Commun] 2018 Aug 15; Vol. 9 (1), pp. 3268. Date of Electronic Publication: 2018 Aug 15.
Autor:
Justice AE; Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Winkler TW; Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine; St. Louis, Missouri, 63108 USA., Graff M; Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Fisher VA; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA., Young K; Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Barata L; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine; St. Louis, Missouri, 63108 USA., Deng X; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA., Czajkowski J; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine; St. Louis, Missouri, 63108 USA., Hadley D; Population Health Research Institute, St. George's, University of London, London, SW17 0RE, UK.; TransMed Systems, Inc., Cupertino, California 95014, USA., Ngwa JS; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA.; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore Maryland, USA., Ahluwalia TS; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Steno Diabetes Center, Gentofte, Denmark., Chu AY; NHLBI Framingham Heart Study, Framingham, Massachusetts, 01702 USA.; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts USA., Heard-Costa NL; NHLBI Framingham Heart Study, Framingham, Massachusetts, 01702 USA.; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts 02118, USA., Lim E; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA., Perez J; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA., Eicher JD; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, The Framingham Heart Study, Framingham, Massachusetts, USA., Kutalik Z; Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss instititute of Bioinformatics., Xue L; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Renström F; Department of Biobank Research, Umeå University, Umeå, Sweden.; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, SE-205 02 Malmö, Sweden., Wu J; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA., Qi Q; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, USA., Ahmad S; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts USA.; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, SE-205 02 Malmö, Sweden.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA., Alfred T; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, USA.; The Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, USA., Amin N; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3015GE, The Netherlands., Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA., Bonnefond A; University of Lille, CNRS, Institut Pasteur of Lille, UMR 8199 - EGID, Lille, France., Bragg J; Internal Medicine - Nephrology, University of Michigan, Ann Arbor, Michigan, USA.; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA., Cadby G; Centre for Genetic Origins of Health and Disease, University of Western Australia, Crawley, Australia., Chittani M; Department of Health Sciences, University of Milan,Via A. Di Rudiní, 8 20142, Milano, Italy., Coggeshall S; Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA., Corre T; Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss instititute of Bioinformatics., Direk N; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Psychiatry, Dokuz Eylul University, Izmir, Turkey., Eriksson J; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden., Fischer K; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia., Gorski M; Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany.; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Neergaard Harder M; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Horikoshi M; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK., Huang T; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.; Epidemiology Domain, Saw Swee Hock School of Public Health, National University of Singapore, Singapore 117549, Singapore., Huffman JE; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, The Framingham Heart Study, Framingham, Massachusetts, USA.; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA., Justesen JM; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Kanoni S; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Kinnunen L; Department of Health, National Institute for Health and Welfare, Helsinki, FI-00271 Finland., Kleber ME; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Komulainen P; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Kumari M; ISER, University of Essex, Colchester CO43SQ, UK.; Department of Epidemiology and Public Health, UCL, London, WC1E 6BT, UK., Lim U; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813, USA., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge CB2 0QQ, UK., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33520, Finland.; Department of Clinical Chemistry, Faculty of Medicine and Life Sciences, University of Tampere, Tampere 33014, Finland., Mangino M; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.; NIHR Biomedical Research Centre at Guy's and St. Thomas' Foundation Trust, London, UK., Manichaikul A; Center for Public Health Genomics and Biostatistics Section, Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia 22903, USA., Marten J; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland., Middelberg RPS; Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Australia., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.; Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, D-81377 Munich, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany., Navarro P; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland., Pérusse L; Department of Kinesiology, Faculty of Medicine, Université Laval, Québec, Canada.; Institute of Nutrition and Functional Foods, Université Laval, Québec, Canada., Pervjakova N; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.; Department of Biotechnology, Institute of Molecular and Cell Biology, University of Tartu, Tartu 51010, Estonia., Sarti C; Department of Social and Health Care, City of Helsinki, Helsinki, Finland., Smith AV; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA., Stančáková A; Department of Medicine, Institute of Clinical Medicine, University of Eastern Finland, 70210 Kuopio, Finland., Strawbridge RJ; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden., Stringham HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA., Sung YJ; Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri, USA., Tanaka T; Translational Gerontology Branch, National Institute on Aging, Baltimore Maryland, USA., Teumer A; Institute for Community Medicine, University Medicine Greifswald, Germany., Trompet S; Department of Cardiology, Leiden University Medical Center, The Netherlands.; Department of Gerontology and Geriatrics, Leiden University Medical Center, The Netherlands., van der Laan SW; Laboratory of Experimental Cardiology, Department of Cardiology, Division Heart &Lungs, UMC Utrecht, The Netherlands., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, The Netherlands., Van Vliet-Ostaptchouk JV; Department of Endocrinology, University of Groningen, University Medical Center Groningen, The Netherlands., Vedantam SL; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston Massachusetts 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA., Verweij N; Department of Cardiology, University Medical Center Groningen, University of Groningen, The Netherlands., Vink JM; Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands.; Behavioural Science Institute, Radboud University, Nijmegen, The Netherlands., Vitart V; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland., Wu Y; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Yengo L; University of Lille, CNRS, Institut Pasteur of Lille, UMR 8199 - EGID, Lille, France., Zhang W; Dept Epidemiology and Biostatistics, School of Public Health, Imperical College London, UK.; Cardiology, Ealing Hospital NHS Trust, Middlesex, UK., Hua Zhao J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge CB2 0QQ, UK., Zimmermann ME; Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany., Zubair N; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle Washington USA., Abecasis GR; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA., Adair LS; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA., Afaq S; Dept Epidemiology and Biostatistics, School of Public Health, Imperical College London, UK.; Cardiology, Ealing Hospital NHS Trust, Middlesex, UK., Afzal U; Dept Epidemiology and Biostatistics, School of Public Health, Imperical College London, UK.; Cardiology, Ealing Hospital NHS Trust, Middlesex, UK., Bakker SJL; Department of Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Bartz TM; Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA.; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington 98101, USA., Beilby J; Busselton Population Medical Research Institute, Nedlands, Western Australia 6009, Australia.; PathWest Laboratory Medicine of WA, Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009, Australia.; School of Pathology and Laboraty Medicine, The University of Western Australia, 35 Stirling Hwy, Crawley, Western Australia 6009, Australia., Bergman RN; Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Bergmann S; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss instititute of Bioinformatics., Biffar R; Clinic for Prosthetic Dentistry, Gerostomatology and Material Science, University Medicine Greifswald, Germany., Blangero J; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville, Texas, USA., Boerwinkle E; Human Genetics Center, The University of Texas Health Science Center, PO Box 20186, Houston, Texas 77225, USA., Bonnycastle LL; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA., Bottinger E; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, USA.; Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, USA., Braga D; Department of Health Sciences, University of Milan,Via A. Di Rudiní, 8 20142, Milano, Italy., Buckley BM; Department of Pharmacology and Therapeutics, University College Cork, Ireland., Buyske S; Department of Genetics, Rutgers University, Piscataway, New Jersey 08854, USA.; Department of Statistics and Biostatistics, Rutgers University, Piscataway, New Jersey 08854, USA., Campbell H; Usher Institute for Population Health Sciences and Informatics, The University of Edinburgh, Scotland, UK., Chambers JC; Cardiology, Ealing Hospital NHS Trust, Middlesex, UK.; Dept Epidemiology and Biostatistics, School of Public Health, Imperical College London, UK.; Imperial College Healthcare NHS Trust, London, UK., Collins FS; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA., Curran JE; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville, Texas, USA., de Borst GJ; Department of Vascular Surgery, Division of Surgical Specialties, UMC Utrecht, The Netherlands., de Craen AJM; Department of Gerontology and Geriatrics, Leiden University Medical Center, The Netherlands., de Geus EJC; Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands.; EMGO+ Institute Vrije Universiteit &Vrije Universiteit Medical Center., Dedoussis G; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece., Delgado GE; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., den Ruijter HM; Laboratory of Experimental Cardiology, Department of Cardiology, Division Heart &Lungs, UMC Utrecht, The Netherlands., Eiriksdottir G; Icelandic Heart Association, Kopavogur, Iceland., Eriksson AL; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden., Esko T; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston Massachusetts 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, USA., Ford I; Robertson Centre for Biostatistics, University of Glasgow, UK., Forrester T; Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona, JMAAW15 Jamaica., Gertow K; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden., Gigante B; Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Glorioso N; Hypertension and Related Disease Centre, AOU-University of Sassari., Gong J; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle Washington USA., Grallert H; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, D-85764 Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.; German Center for Diabetes Research, D-85764 Neuherberg, Germany., Grammer TB; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Grarup N; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Haitjema S; Laboratory of Experimental Cardiology, Department of Cardiology, Division Heart &Lungs, UMC Utrecht, The Netherlands., Hallmans G; Department of Public Health and Clinical Medicine, Section for Nutritional Research, Umeå University, Umeå, Sweden., Hamsten A; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden., Hansen T; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Harris TB; Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA., Hartman CA; Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands., Hassinen M; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Hastie ND; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland., Heath AC; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA., Hernandez D; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA., Hindorff L; Division of Genomic Medicine, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA., Hocking LJ; Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK.; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, Scotland., Hollensted M; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Holmen OL; St. Olav Hospital, Trondheim University Hospital, Trondheim, Norway., Homuth G; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Germany., Jan Hottenga J; Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands., Huang J; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK., Hung J; School of Medicine and Pharmacology, The University of Western Australia, 25 Stirling Hwy, Crawley, Western Australia 6009, Australia.; Department of Cardiovascular Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009, Australia., Hutri-Kähönen N; Department of Pediatrics, Tampere University Hospital, Tampere 33521, Finland.; Department of Pediatrics, Faculty of Medicine and Life Sciences, University of Tampere, Tampere 33014, Finland., Ingelsson E; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, 751 85, Sweden.; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.; Science for Life Laboratory, Uppsala University, Uppsala, 750 85, Sweden., James AL; Busselton Population Medical Research Institute, Nedlands, Western Australia 6009, Australia.; School of Medicine and Pharmacology, The University of Western Australia, 25 Stirling Hwy, Crawley, Western Australia 6009, Australia.; Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009, Australia., Jansson JO; Department of Physiology, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden., Jarvelin MR; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment &Health, School of Public Health, Imperial College London, UK.; Center for Life Course Epidemiology, Faculty of Medicine, University of OuluP.O.Box 5000, FI-90014, Finland.; Biocenter Oulu, University of Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, Kajaanintie 50, P.O.Box 20, FI-90220, 90029 Oulu, Finland., Jhun MA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA., Jørgensen ME; Steno Diabetes Center, Gentofte, Denmark., Juonala M; Department of Medicine, University of Turku, Turku 20520 Finland.; Division of Medicine, Turku University Hospital, Turku 20521, Finland., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere 33521, Finland.; Department of Clinical Physiology, Faculty of Medicine and Life Sciences, University of Tampere, Tampere 33014, Finland., Karlsson M; Clinical and Molecular Osteoporosis Research Unit, Department of Orthopedics and Clinical Sciences, Skåne University Hospital, Lund University, Malmö, Sweden., Koistinen HA; Department of Health, National Institute for Health and Welfare, Helsinki, FI-00271 Finland.; Department of Medicine and Abdominal Center: Endocrinology, University of Helsinki and Helsinki University Central Hospital, Helsinki, FI-00029 Finland.; Minerva Foundation Institute for Medical Research, Biomedicum 2U, Helsinki, FI-00290 Finland., Kolcic I; Department of Public Health, Faculty of Medicine, University of Split, Croatia., Kolovou G; Department of Cardiology, Onassis Cardiac Surgery Center, Athens, Greece., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle Washington USA., Krämer BK; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Kuusisto J; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, 70210 Kuopio, Finland., Kvaløy K; HUNT Research Centre, Department of Public Health and Nursing, Norwegian University of Science and Technology, 7600 Levanger, Norway., Lakka TA; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio Campus, Finland., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge CB2 0QQ, UK., Launer LJ; Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA., Leander K; Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Lee NR; USC-Office of Population Studies Foundation, Inc., University of San Carlos, Cebu City 6000, Philippines.; Department of Anthropology, Sociology and History, University of San Carlos, Cebu City 6000, Philippines., Lind L; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala 751 85, Sweden., Lindgren CM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Li Ka Shing Centre for Health Information and Discovery, The Big Data Institute, University of Oxford, Oxford OX3 7BN, UK., Linneberg A; Research Centre for Prevention and Health, the Capital Region of Denmark, Copenhagen, Denmark.; Department of Clinical Experimental Research, Rigshospitalet, Glostrup, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Lobbens S; University of Lille, CNRS, Institut Pasteur of Lille, UMR 8199 - EGID, Lille, France., Loh M; Dept Epidemiology and Biostatistics, School of Public Health, Imperical College London, UK.; Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore 138648, Singapore., Lorentzon M; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden., Luben R; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Lubke G; Department of Psychology, University of Notre Dame, Notre Dame, USA., Ludolph-Donislawski A; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, D-81377 Munich, Germany., Lupoli S; Department of Health Sciences, University of Milan,Via A. Di Rudiní, 8 20142, Milano, Italy., Madden PAF; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA., Männikkö R; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Marques-Vidal P; Department of Medicine, Internal Medicine, Lausanne university hospital (CHUV), Lausanne, Switzerland., Martin NG; Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Australia., McKenzie CA; Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona, JMAAW15 Jamaica., McKnight B; Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA.; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington 98101, USA.; Program in Biostatistics and Biomathematics, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA., Mellström D; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden., Menni C; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Montgomery GW; Molecular Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Musk AB; Busselton Population Medical Research Institute, Nedlands, Western Australia 6009, Australia.; School of Population Health, The University of Western Australia, 35 Stirling Hwy, Crawley, Western Australia 6009, Australia.; Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009, Australia., Narisu N; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA., Nauck M; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Germany., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, The Netherlands., Oldehinkel AJ; Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands., Olden M; Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany., Ong KK; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge CB2 0QQ, UK., Padmanabhan S; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, Scotland.; Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Scotland., Peyser PA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA., Pisinger C; Research Center for Prevention and Health, Glostrup Hospital, Glostrup Denmark.; Department of Public Health, Faculty of Health Sciences, University of Copenhagen, Denmark., Porteous DJ; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, Scotland.; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku 20521, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku 20520, Finland., Rankinen T; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA., Rao DC; Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri, USA.; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA., Rasmussen-Torvik LJ; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Rawal R; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, D-85764 Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany., Rice T; Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri, USA.; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts USA.; Division of Cardiology, Brigham and Women's Hospital, Boston, Massachusetts, USA., Rose LM; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts USA., Bien SA; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle Washington USA., Rudan I; Usher Institute for Population Health Sciences and Informatics, The University of Edinburgh, Scotland, UK., Sanna S; Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale Delle Ricerche (CNR), Cittadella Universitaria di Monserrato, 09042, Monserrato, Italy., Sarzynski MA; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA., Sattar N; BHF Glasgow Cardiovascular Research Centre, Faculty of Medicine, Glasgow, UK., Savonen K; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Schlessinger D; Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA., Scholtens S; Department of Epidemiology, University of Groningen, University Medical Center Groningen, The Netherlands., Schurmann C; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, USA.; The Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, USA., Scott RA; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge CB2 0QQ, UK., Sennblad B; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden.; Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden., Siemelink MA; Laboratory of Experimental Cardiology, Department of Cardiology, Division Heart &Lungs, UMC Utrecht, The Netherlands., Silbernagel G; Division of Angiology, Department of Internal Medicine, Medical University of Graz, Austria., Slagboom PE; Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, The Netherlands., Staessen JA; Research Unit Hypertension and Cardiovascular Epidemiology, Department of Cardiovascular Science , University of Leuven, Campus Sint Rafael, Kapucijnenvoer 35, Leuven; Belgium.; R&D VitaK Group, Maastricht University, Brains Unlimited Building, Oxfordlaan 55, Maastricht, The Netherlands., Stott DJ; Institute of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, UK., Swertz MA; Department of Genetics, University of Groningen, University Medical Center Groningen, The Netherlands., Swift AJ; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA., Taylor KD; Center for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor/UCLA Medical Center, Torrance, California, USA.; Department of Pediatrics, University of California Los Angeles, Los Angeles, California, USA., Tayo BO; Department of Public Health Sciences, Stritch School of Medicine, Loyola University of Chicago, Maywood, Illinois 61053, USA., Thorand B; Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.; German Center for Diabetes Research, D-85764 Neuherberg, Germany., Thuillier D; University of Lille, CNRS, Institut Pasteur of Lille, UMR 8199 - EGID, Lille, France., Tuomilehto J; Research Division, Dasman Diabetes Institute, Dasman, Kuwait.; Department of Neurosciences and Preventive Medicine, Danube-University Krems, 3500 Krems, Austria.; Saudi Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Uitterlinden AG; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands., Vandenput L; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden., Vohl MC; Institute of Nutrition and Functional Foods, Université Laval, Québec, Canada.; School of Nutrition, Université Laval, Québec, Canada., Völzke H; Institute for Community Medicine, University Medicine Greifswald, Germany., Vonk JM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, The Netherlands., Waeber G; Department of Medicine, Internal Medicine, Lausanne university hospital (CHUV), Lausanne, Switzerland., Waldenberger M; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, D-85764 Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany., Westendorp RGJ; Department of Public Health, and Center for Healthy Ageing, University of Copenhagen, Denmark., Wild S; Usher Institute for Population Health Sciences and Informatics, The University of Edinburgh, Scotland, UK., Willemsen G; Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands., Wolffenbuttel BHR; Department of Endocrinology, University of Groningen, University Medical Center Groningen, The Netherlands., Wong A; MRC Unit for Lifelong Health and Ageing at UCL, 33 Bedford Place, London, WC1B 5JU, UK., Wright AF; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland., Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA., Zillikens MC; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Baldassarre D; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy.; Centro Cardiologico Monzino, IRCCS, Milan, Italy., Balkau B; Inserm U-1018, CESP, 94807 Villejuif cedex France., Bandinelli S; Geriatric Unit, Azienda USL Toscana centro, Florence Italy., Böger CA; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Boomsma DI; Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands., Bouchard C; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA., Bruinenberg M; Lifelines Cohort Study, PO Box 30001, 9700 RB Groningen, The Netherlands., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts USA.; Division of Genetics, Brigham and Women's Hospital, Boston, Massachusetts, USA., Chen YD; Institute for Translational Genomics and Population Sciences, Los Angeles BioMedical Research Institute and Department of Pediatrics, Harbor-UCLA, Torrance, California 90502, USA., Chines PS; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA., Cooper RS; Department of Public Health Sciences, Stritch School of Medicine, Loyola University of Chicago, Maywood, Illinois 61053, USA., Cucca F; Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale Delle Ricerche (CNR), Cittadella Universitaria di Monserrato, 09042, Monserrato, Italy.; Dipartimento di Scienze Biomediche, Universita' degli Studi di Sassari, Sassari, Italy., Cusi D; Sanipedia srl, Bresso (Milano), Italy and Institute of Biomedical Technologies National Centre of Research Segrate, Milano, Italy., Faire U; Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Ferrucci L; Translational Gerontology Branch, National Institute on Aging, Baltimore Maryland, USA., Franks PW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, SE-205 02 Malmö, Sweden.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.; Department of Public Health &Clinical Medicine, Umeå University, Umeå, Sweden., Froguel P; University of Lille, CNRS, Institut Pasteur of Lille, UMR 8199 - EGID, Lille, France.; Department of Genomics of Common Disease, Imperial College London, London, UK., Gordon-Larsen P; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.; Carolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill North Carolina, 27516, USA., Grabe HJ; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Germany.; German Center for Neurodegenerative Diseases (DZNE), Site Rostock/Greifswald, Germany., Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Haiman CA; Department of Preventive Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, 90089, USA., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, Scotland., Hveem K; HUNT Research Centre, Department of Public Health and Nursing, Norwegian University of Science and Technology, 7600 Levanger, Norway., Johnson AD; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, The Framingham Heart Study, Framingham, Massachusetts, USA., Wouter Jukema J; Department of Cardiology, Leiden University Medical Center, The Netherlands.; Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands.; Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA., Kivimaki M; Department of Epidemiology and Public Health, UCL, London, WC1E 6BT, UK., Kooner JS; Faculty of Med, National Heart &Lung Institute, Cardiovascular Science, Hammersmith Campus, Hammersmith Hospital, Hammersmith Campus, Imperial College London, UK.; Cardiology, Ealing Hospital NHS Trust, Middlesex, UK.; Imperial College Healthcare NHS Trust, London, UK., Kuh D; MRC Unit for Lifelong Health and Ageing at UCL, 33 Bedford Place, London, WC1B 5JU, UK., Laakso M; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, 70210 Kuopio, Finland., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33520, Finland.; Department of Clinical Chemistry, Faculty of Medicine and Life Sciences, University of Tampere, Tampere 33014, Finland., Marchand LL; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813, USA., März W; Synlab Academy, Synlab Services GmbH, Mannheim, Germany.; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria., McCarthy MI; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Oxford National Institute for Health Research (NIHR) Biomedical Research Centre, Churchill Hospital, Oxford, UK., Metspalu A; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia., Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Department of Biostatistics, University of Liverpool, Liverpool L69 3GL, UK., Ohlsson C; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden., Palmer LJ; School of Public Health, University of Adelaide, Adelaide, South Australia, Australia., Pasterkamp G; Laboratory of Experimental Cardiology, Department of Cardiology, Division Heart &Lungs, UMC Utrecht, The Netherlands.; Laboratory of Clinical Chemistry and Hematology, Division Laboratories &Pharmacy, UMC Utrecht, The Netherlands., Pedersen O; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Peters A; Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.; German Center for Diabetes Research, D-85764 Neuherberg, Germany., Peters U; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle Washington USA., Polasek O; Usher Institute for Population Health Sciences and Informatics, The University of Edinburgh, Scotland, UK.; Department of Public Health, Faculty of Medicine, University of Split, Croatia., Psaty BM; Department of Medicine, University of Washington, Seattle, Washington 98195, USA.; Department of Epidemiology, University of Washington, Seattle, Washington 98101, USA.; Group Health Research Institute, Group Health Cooperative, Seattle, Washington 98101, USA., Qi L; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.; Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana, USA., Rauramaa R; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Smith BH; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, Scotland.; Division of Population Health Sciences, Ninewells Hospital and Medical School, University of Dundee, Dundee, DD2 4RB, Scotland., Sørensen TIA; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Epidemiology (formerly Institute of Preventive Medicine), Bispebjerg and Frederiksberg Hospital (2000 Frederiksberg), The Capital Region, Copenhagen, Denmark.; MRC Integrative Epidemiology Unit, Bristol University, Bristol, UK., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, D-81377 Munich, Germany., Tiemeier H; Department of Psychiatry Erasmus Medical Center, Rotterdam, The Netherlands., Tremoli E; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy.; Centro Cardiologico Monzino, IRCCS, Milan, Italy., van der Harst P; Department of Cardiology, University Medical Center Groningen, University of Groningen, The Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, The Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, The Netherlands., Vestergaard H; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Steno Diabetes Center, Gentofte, Denmark., Vollenweider P; Department of Medicine, Internal Medicine, Lausanne university hospital (CHUV), Lausanne, Switzerland., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge CB2 0QQ, UK., Weir DR; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, USA., Whitfield JB; Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Australia., Wilson JF; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.; Usher Institute for Population Health Sciences and Informatics, The University of Edinburgh, Scotland, UK., Tyrrell J; Genetics of Complex Traits, University of Exeter Medical School, RILD Building University of Exeter, Exeter, EX2 5DW, UK.; European Centre for Environment and Human Health, University of Exeter Medical School, The Knowledge Spa, Truro TR1 3HD, UK., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK., Barroso I; Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.; NIHR Cambridge Biomedical Research Centre, Level 4, Institute of Metabolic Science Box 289 Addenbrooke's Hospital Cambridge CB2 OQQ, UK.; University of Cambridge Metabolic Research Laboratories, Level 4, Institute of Metabolic Science Box 289 Addenbrooke's Hospital Cambridge CB2 OQQ, UK., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA., Deloukas P; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia., Fox CS; NHLBI Framingham Heart Study, Framingham, Massachusetts, 01702 USA., Hirschhorn JN; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston Massachusetts 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA.; Department of Genetics, Harvard Medical School, Boston Massachusetts 02115, USA., Hunter DJ; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Strachan DP; Population Health Research Institute, St. George's, University of London, London, SW17 0RE, UK.; Division of Population Health Sciences and Education, St George's, University of London, London SW17 0RE, UK., van Duijn CM; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3015GE, The Netherlands.; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA). Leiden, The Netherlands.; Center for Medical Systems Biology, Leiden, The Netherlands., Heid IM; Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany.; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg 85764, Germany., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Marchini J; Department of Statistics, University of Oxford, Oxford, UK., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, USA.; The Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, USA.; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge CB2 0QQ, UK.; Mount Sinai School of Medicine, New York 10029, USA.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, USA., Kilpeläinen TO; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge CB2 0QQ, UK.; Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, 10029, USA., Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA., Borecki IB; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine; St. Louis, Missouri, 63108 USA., North KE; Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Cupples LA; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA.; NHLBI Framingham Heart Study, Framingham, Massachusetts, 01702 USA.
Publikováno v:
Nature communications [Nat Commun] 2017 Apr 26; Vol. 8, pp. 14977. Date of Electronic Publication: 2017 Apr 26.
Autor:
Joehanes R; The Framingham Heart Study and the Division of Intramural Research, National Heart, Lung and Blood Institute, National Institutes of Health, 73 Mt. Wayte Avenue, Suite 2, Framingham, MA, 01702, USA.; Mathematical and Statistical Computing Laboratory, Center for Information Technology, National Institutes of Health, Bethesda, MD, USA.; Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School, Boston, MA, USA., Zhang X; The Framingham Heart Study and the Division of Intramural Research, National Heart, Lung and Blood Institute, National Institutes of Health, 73 Mt. Wayte Avenue, Suite 2, Framingham, MA, 01702, USA.; Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA.; Section of Biomedical Genetics, Department of Medicine, Boston University School of Medicine, Boston, MA, USA., Huan T; The Framingham Heart Study and the Division of Intramural Research, National Heart, Lung and Blood Institute, National Institutes of Health, 73 Mt. Wayte Avenue, Suite 2, Framingham, MA, 01702, USA., Yao C; The Framingham Heart Study and the Division of Intramural Research, National Heart, Lung and Blood Institute, National Institutes of Health, 73 Mt. Wayte Avenue, Suite 2, Framingham, MA, 01702, USA., Ying SX; Mathematical and Statistical Computing Laboratory, Center for Information Technology, National Institutes of Health, Bethesda, MD, USA., Nguyen QT; Mathematical and Statistical Computing Laboratory, Center for Information Technology, National Institutes of Health, Bethesda, MD, USA., Demirkale CY; Mathematical and Statistical Computing Laboratory, Center for Information Technology, National Institutes of Health, Bethesda, MD, USA., Feolo ML; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA., Sharopova NR; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA., Sturcke A; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA., Schäffer AA; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA., Heard-Costa N; Department of Neurology, Boston University School of Medicine, Boston, MA, USA., Chen H; School of Public Health, Harvard University, Boston, MA, USA.; Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA., Liu PC; DNA Sequencing and Genomics Core, National Institutes of Health, Bethesda, MD, USA., Wang R; DNA Sequencing and Genomics Core, National Institutes of Health, Bethesda, MD, USA., Woodhouse KA; DNA Sequencing and Genomics Core, National Institutes of Health, Bethesda, MD, USA., Tanriverdi K; Department of Medicine, University of Massachusetts Medical School, Worchester, MA, USA., Freedman JE; Department of Medicine, University of Massachusetts Medical School, Worchester, MA, USA., Raghavachari N; National Institute on Aging, National Institutes of Health, Bethesda, MD, USA., Dupuis J; The Framingham Heart Study and the Division of Intramural Research, National Heart, Lung and Blood Institute, National Institutes of Health, 73 Mt. Wayte Avenue, Suite 2, Framingham, MA, 01702, USA.; Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA., Johnson AD; The Framingham Heart Study and the Division of Intramural Research, National Heart, Lung and Blood Institute, National Institutes of Health, 73 Mt. Wayte Avenue, Suite 2, Framingham, MA, 01702, USA., O'Donnell CJ; The Framingham Heart Study and the Division of Intramural Research, National Heart, Lung and Blood Institute, National Institutes of Health, 73 Mt. Wayte Avenue, Suite 2, Framingham, MA, 01702, USA.; Cardiology Section, Department of Medicine, Boston VA Healthcare, Boston, MA, USA., Levy D; The Framingham Heart Study and the Division of Intramural Research, National Heart, Lung and Blood Institute, National Institutes of Health, 73 Mt. Wayte Avenue, Suite 2, Framingham, MA, 01702, USA. levyd@nhlbi.nih.gov., Munson PJ; Mathematical and Statistical Computing Laboratory, Center for Information Technology, National Institutes of Health, Bethesda, MD, USA. munson@mail.nih.gov.; National Institutes of Health, Bldg 12A, Room 2003, Bethesda, MD, 20892-5626, USA. munson@mail.nih.gov.
Publikováno v:
Genome biology [Genome Biol] 2017 Jan 25; Vol. 18 (1), pp. 16. Date of Electronic Publication: 2017 Jan 25.
Autor:
Zhang X; 1] Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, Maryland, USA. [2] National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts, USA., Joehanes R; 1] Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, Maryland, USA. [2] National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts, USA. [3] Mathematical and Statistical Computing Laboratory, Center for Information Technology, US National Institutes of Health, Bethesda, Maryland, USA., Chen BH; 1] Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, Maryland, USA. [2] National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts, USA., Huan T; 1] Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, Maryland, USA. [2] National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts, USA., Ying S; Mathematical and Statistical Computing Laboratory, Center for Information Technology, US National Institutes of Health, Bethesda, Maryland, USA., Munson PJ; Mathematical and Statistical Computing Laboratory, Center for Information Technology, US National Institutes of Health, Bethesda, Maryland, USA., Johnson AD; 1] Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, Maryland, USA. [2] National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts, USA., Levy D; 1] Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, Maryland, USA. [2] National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts, USA., O'Donnell CJ; 1] Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, Maryland, USA. [2] National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts, USA. [3] Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Publikováno v:
Nature genetics [Nat Genet] 2015 Apr; Vol. 47 (4), pp. 345-52. Date of Electronic Publication: 2015 Feb 16.
Autor:
Huan T; 1] The Framingham Heart Study, Framingham, Massachusetts 01702, USA [2] The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, Maryland 20824, USA., Rong J; Department of Mathematics and Statistics, Boston University, Boston, Massachusetts 02118, USA., Liu C; 1] The Framingham Heart Study, Framingham, Massachusetts 01702, USA [2] The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, Maryland 20824, USA., Zhang X; 1] The Framingham Heart Study, Framingham, Massachusetts 01702, USA [2] Cardiovascular Epidemiology and Human Genomics Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Bethesda, Maryland 20824, USA., Tanriverdi K; Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA., Joehanes R; 1] The Framingham Heart Study, Framingham, Massachusetts 01702, USA [2] The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, Maryland 20824, USA [3] Mathematical and Statistical Computing Laboratory, Center for Information Technology, National Institutes of Health, Bethesda, Maryland 20824, USA [4] Harvard Medical School, Harvard University, Boston, Massachusetts 02115, USA [5] Hebrew SeniorLife, Boston, Massachusetts 02131, USA., Chen BH; 1] The Framingham Heart Study, Framingham, Massachusetts 01702, USA [2] The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, Maryland 20824, USA., Murabito JM; 1] The Framingham Heart Study, Framingham, Massachusetts 01702, USA [2] Department of Medicine, Section of General Internal Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA., Yao C; 1] The Framingham Heart Study, Framingham, Massachusetts 01702, USA [2] The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, Maryland 20824, USA., Courchesne P; 1] The Framingham Heart Study, Framingham, Massachusetts 01702, USA [2] The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, Maryland 20824, USA., Munson PJ; Mathematical and Statistical Computing Laboratory, Center for Information Technology, National Institutes of Health, Bethesda, Maryland 20824, USA., O'Donnell CJ; 1] The Framingham Heart Study, Framingham, Massachusetts 01702, USA [2] Cardiovascular Epidemiology and Human Genomics Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Bethesda, Maryland 20824, USA., Cox N; Department of Human Genetics, University of Chicago, Chicago, Illinois 60637, USA., Johnson AD; 1] The Framingham Heart Study, Framingham, Massachusetts 01702, USA [2] Cardiovascular Epidemiology and Human Genomics Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Bethesda, Maryland 20824, USA., Larson MG; 1] The Framingham Heart Study, Framingham, Massachusetts 01702, USA [2] Department of Mathematics and Statistics, Boston University, Boston, Massachusetts 02118, USA., Levy D; 1] The Framingham Heart Study, Framingham, Massachusetts 01702, USA [2] The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, Maryland 20824, USA., Freedman JE; Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA.
Publikováno v:
Nature communications [Nat Commun] 2015 Mar 20; Vol. 6, pp. 6601. Date of Electronic Publication: 2015 Mar 20.
Autor:
Handelman SK, Seweryn M, Smith RM, Hartmann K, Wang D, Pietrzak M, Johnson AD, Kloczkowski A, Sadee W
Publikováno v:
BMC genomics [BMC Genomics] 2015; Vol. 16 Suppl 8, pp. S8. Date of Electronic Publication: 2015 Jun 18.
Autor:
Keller MF; Laboratory of Neurogenetics Department of Biological Anthropology, Temple University, Philadelphia, PA, USA., Reiner AP; Department of Epidemiology Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Okada Y; Laboratory for Statistical Analysis Department of Human Genetics and Disease Diversity, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan., van Rooij FJ; Department of Epidemiology Consortium for Healthy Aging (NGI-NCHA), The Netherlands Genomics Initiative, Leiden, The Netherlands., Johnson AD; Cardiovascular Epidemiology and Human Genomics Branch, NHLBI Division of Intramural Research, Bethesda, MD, USA NHLBI Framingham Heart Study, Bethesda, MD, USA., Chen MH; Department of Neurology, Boston University School of Medicine, Boston, MA, USA NHLBI Framingham Heart Study, Bethesda, MD, USA., Smith AV; Icelandic Heart Association, Kopavogur, Iceland University of Iceland, Reykjavik, Iceland., Morris AP; Genetic and Genomic Epidemiology Unit, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK Department of Biostatistics, University of Liverpool, Liverpool, UK., Tanaka T; Longitudinal Studies Section, Clinical Research Branch., Ferrucci L; Longitudinal Studies Section, Clinical Research Branch., Zonderman AB; Behavioral Epidemiology Section, Laboratory of Epidemiology & Population Sciences, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, MD, USA., Lettre G; Montreal Heart Institute, Montréal, Canada Département de Médecine, Université de Montréal, Montréal, Canada., Harris T; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA., Garcia M; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA., Bandinelli S; Geriatric Rehabilitation Unit, Azienda Sanitaria Firenze (ASF), Florence, Italy., Qayyum R; GeneSTAR Research Program, Division of General Internal Medicine., Yanek LR; GeneSTAR Research Program, Division of General Internal Medicine., Becker DM; GeneSTAR Research Program, Division of General Internal Medicine., Becker LC; GeneSTAR Research Program, Division of General Internal Medicine Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD, USA., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Keating B; Center for Applied Genomics, Children's Hospital of Philadelphia, PA, USA Department of Pediatrics, University of Pennsylvania, PA, USA., Reis J; Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda, MD, USA., Tang H; Stanford University School of Medicine, Stanford, CA 94305, USA., Boerwinkle E; The Brown Foundation, Institute of Molecular Medicine for the Prevention of Human Diseases, University of Texas, Houston, TX, USA., Kamatani Y; Laboratory for Statistical Analysis., Matsuda K; Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan., Kamatani N; Laboratory for Statistical Analysis., Nakamura Y; Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan Department of Medicine Department of Surgery, Center for Personalized Therapeutics, The University of Chicago, Chicago, IL, USA., Kubo M; Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Liu S; Department of Epidemiology Department of Medicine, Brown University, Providence, RI, USA., Dehghan A; Department of Epidemiology Consortium for Healthy Aging (NGI-NCHA), The Netherlands Genomics Initiative, Leiden, The Netherlands., Felix JF; Department of Epidemiology Consortium for Healthy Aging (NGI-NCHA), The Netherlands Genomics Initiative, Leiden, The Netherlands., Hofman A; Department of Epidemiology Consortium for Healthy Aging (NGI-NCHA), The Netherlands Genomics Initiative, Leiden, The Netherlands., Uitterlinden AG; Department of Epidemiology Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands Consortium for Healthy Aging (NGI-NCHA), The Netherlands Genomics Initiative, Leiden, The Netherlands., van Duijn CM; Department of Epidemiology Consortium for Healthy Aging (NGI-NCHA), The Netherlands Genomics Initiative, Leiden, The Netherlands., Franco OH; Department of Epidemiology ErasmusAGE, Department of Epidemiology Consortium for Healthy Aging (NGI-NCHA), The Netherlands Genomics Initiative, Leiden, The Netherlands., Longo DL; Laboratory of Genetics., Singleton AB; Laboratory of Neurogenetics., Psaty BM; Cardiovascular Health Research Unit Department of Medicine Department of Epidemiology and Health Services, University of Washington, Seattle, WA, USA Group Health Research Institute, Group Health Cooperative, Seattle, WA, USA., Evans MK; Health Disparities Research Section, Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Cupples LA; NHLBI Framingham Heart Study, Bethesda, MD, USA Boston University Department of Statistics, Boston, MA, USA., Rotter JI; Institute for Translational Genomics and Population Sciences, Los Angeles BioMedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA Division of Genetic Outcomes, Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA., O'Donnell CJ; Cardiovascular Epidemiology and Human Genomics Branch, NHLBI Division of Intramural Research, Bethesda, MD, USA NHLBI Framingham Heart Study, Bethesda, MD, USA., Takahashi A; Laboratory for Statistical Analysis., Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA., Ganesh SK; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA sganesh@med.umich.edu nallsm@mail.nih.gov., Nalls MA; Laboratory of Neurogenetics sganesh@med.umich.edu nallsm@mail.nih.gov.
Publikováno v:
Human molecular genetics [Hum Mol Genet] 2014 Dec 20; Vol. 23 (25), pp. 6944-60. Date of Electronic Publication: 2014 Aug 05.