Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Godfrey, S."'
Autor:
Godfrey S. Getz
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 5, Pp 745-748 (2018)
Externí odkaz:
https://doaj.org/article/5829105bd16c4d09b2707e68643b471d
Autor:
Godfrey S. Getz, Catherine A. Reardon
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 5, Pp 758-766 (2016)
ApoE is a multifunctional protein that is expressed by many cell types that influences many aspects of cardiovascular physiology. In humans, there are three major allelic variants that differentially influence lipoprotein metabolism and risk for the
Externí odkaz:
https://doaj.org/article/031c09eb5f1842d1af6eecc3ba80952b
Autor:
Nathalie Pamir, Patrick Hutchins, Graziella Ronsein, Tomas Vaisar, Catherine A. Reardon, Godfrey S. Getz, Aldons J. Lusis, Jay W. Heinecke
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 2, Pp 246-257 (2016)
Cholesterol efflux capacity associates strongly and negatively with the incidence and prevalence of human CVD. We investigated the relationships of HDL's size and protein cargo with its cholesterol efflux capacity using APOB-depleted serum and HDLs i
Externí odkaz:
https://doaj.org/article/0ddc1206bf254b4a932d318672fb83b5
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 2, Pp 215-226 (2015)
apoE is a multi-functional protein expressed in several cell types and in several organs. It is highly expressed in adipose tissue, where it is important for modulating adipocyte lipid flux and gene expression in isolated adipocytes. In order to inve
Externí odkaz:
https://doaj.org/article/07a58f2dc25940de9a40ef6270a8fc9a
Autor:
Timothy J. Sontag, Bijoy Chellan, Clarissa V. Bhanvadia, Godfrey S. Getz, Catherine A. Reardon
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 2, Pp 470-483 (2015)
Macrophage conversion to atherosclerotic foam cells is partly due to the balance of uptake and efflux of cholesterol. Cholesterol efflux from cells by HDL and its apoproteins for subsequent hepatic elimination is known as reverse cholesterol transpor
Externí odkaz:
https://doaj.org/article/f2f79e5fa1e84c88befdd6f29065b7fb
Autor:
Savitha Subramanian, Michael S. Turner, Yilei Ding, Leela Goodspeed, Shari Wang, Jane H. Buckner, Kevin O'Brien, Godfrey S. Getz, Catherine A. Reardon, Alan Chait
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 10, Pp 2831-2841 (2013)
Obesity is a chronic inflammatory state characterized by infiltration of adipose tissue by immune cell populations, including T lymphocytes. Natural killer T (NKT) cells, a specialized lymphocyte subset recognizing lipid antigens, can be pro- or anti
Externí odkaz:
https://doaj.org/article/23a12788d7474eb28246d48885291959
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 9, Pp 2515-2524 (2013)
Inbred strains of mice with differing susceptibilities to atherosclerosis possess widely varying plasma HDL levels. Cholesterol absorption and lipoprotein formation were compared between atherosclerosis-susceptible, low-HDL C57BL6/J mice and atherosc
Externí odkaz:
https://doaj.org/article/3d05dd66116e4377a7efd41474ba3322
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 10, Pp 1983-1985 (2014)
Externí odkaz:
https://doaj.org/article/a70bc44e075846b681d7cbfff2aae00d
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 1, Pp 202-213 (2013)
The synthesis of apoE by adipocytes has profound effects on adipose tissue lipid flux and gene expression. Using adipose tissue transplantation from wild-type (WT) to apoE knockout (EKO) mice, we show that adipose tissue also contributes to circulati
Externí odkaz:
https://doaj.org/article/504272f63e9348aeb8b780a2d1474166
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 5, Pp 951-963 (2012)
Plasma HDL levels are inversely associated with atherosclerosis. Inbred mouse strains differ in plasma HDL levels and susceptibility to atherosclerosis. Atherosclerosis-susceptible C57BL/6J mice possess plasma HDL levels 2-fold lower than atheroscler
Externí odkaz:
https://doaj.org/article/8d22ec85ee174434919ec1e2ea673373