Zobrazeno 21 - 30
of 51
pro vyhledávání: '"Angelo M. De Marzo"'
Autor:
Tamara L. Lotan, William G. Nelson, Angelo M. De Marzo, Srinivasan Yegnasubramanian, Michael C. Haffner
Publikováno v:
Cancer Prevention Research. 9:648-656
High-grade prostatic intraepithelial neoplasia (PIN) has been accepted as the main precursor lesion to invasive adenocarcinoma of the prostate, and this is likely to be the case. However, in an unknown number of cases, lesions fulfilling the diagnost
Autor:
Lucas A. Horn, Ibrahim Kulac, Charles J. Bieberich, Angelo M. De Marzo, Ryan P. McMullin, Gretchen K. Hubbard, Daniella Bianchi-Frias, May Khalili, Laura N. Mutton, Michael S. Moubarek, Jessica L. Hicks, Srinivasan Yegnasubramanian, Peter S. Nelson
Publikováno v:
Cancer Research. 76:283-292
Genetic instability, a hallmark feature of human cancers including prostatic adenocarcinomas, is considered a driver of metastasis. Somatic copy number alterations (CNA) are found in most aggressive primary human prostate cancers, and the overall num
Autor:
Ashley E. Ross, Angelo M. De Marzo, David M. Berman, Tamara L. Lotan, Tamara Jamaspishvili, Jeremy A. Squire, Howard I. Scher
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Genomic aberrations of the PTEN tumour suppressor gene are among the most common in prostate cancer. Inactivation of PTEN by deletion or mutation is identified in ∼20% of primary prostate tumour samples at radical prostatectomy and in as many as 50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dc5495c3db67ca990b6a6ab6817a5d2
Autor:
Antoun Toubaji, Jonathan I. Epstein, Angelo M. De Marzo, Mehsati Herawi, Tamara L. Lotan, George J. Netto, Jessica Hicks, Roula Albadine, Carlos L. Morais
Publikováno v:
The Prostate. 75:1610-1619
BACKGROUND Prostatic ductal adenocarcinoma is an unusual and aggressive morphologic subtype of prostate cancer. PTEN gene deletion and ERG gene rearrangement are among the most common genomic changes in acinar prostate cancers. Though ductal adenocar
Autor:
Jeong S. Han, Michael S. Nagar, Ming Zhou, Angelo M. De Marzo, Ann E. Anderson, Rajal B. Shah, Jennifer Gordetsky, Cristina Magi-Galluzzi, Jessica Hicks, Jonathan I. Epstein, Tamara L. Lotan, Stephen J. Lee, Carlos L. Morais
Publikováno v:
American Journal of Surgical Pathology. 39:169-178
Intraductal carcinoma of the prostate and high-grade prostatic intraepithelial neoplasia (PIN) have markedly different implications for patient care but can be difficult to distinguish in needle biopsies. In radical prostatectomies, we demonstrated t
Autor:
Charles C. Guo, Yair Lotan, Mohammad Abufaraj, Beat Foerster, Alexander Bachmann, Kilian M. Gust, Nathalie Rioux-Leclercq, Alon Z. Weizer, Francesca Khani, Andrea Haitel, Malte Rieken, Vitaly Margulis, Christopher G. Wood, Angelo M. De Marzo, Shahrokh F. Shariat, Karim Bensalah, Brian D. Robinson, Jay D. Raman, Jose A. Karam
Publikováno v:
Journal of Urology
Journal of Urology, Elsevier, 2017, 198 (6), pp.1269-1277. ⟨10.1016/j.juro.2017.06.096⟩
Journal of Urology, 2017, 198 (6), pp.1269-1277. ⟨10.1016/j.juro.2017.06.096⟩
Journal of Urology, Elsevier, 2017, 198 (6), pp.1269-1277. ⟨10.1016/j.juro.2017.06.096⟩
Journal of Urology, 2017, 198 (6), pp.1269-1277. ⟨10.1016/j.juro.2017.06.096⟩
To our knowledge the frequency and prognostic significance of PTEN protein expression in upper tract urothelial carcinoma have not yet been investigated in large studies. We analyzed PTEN protein status and its association with disease recurrence and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdd398a1c541e0285e61ba70b8aa6d38
https://hal.archives-ouvertes.fr/hal-02449063
https://hal.archives-ouvertes.fr/hal-02449063
Autor:
Beerinder S. Karir, Gissou Azabdaftari, Angelo M. De Marzo, Jong Wook Kim, Franklin W. Huang, Stephanie A. Mullane, Matan Hofree, Levi A. Garraway, Saud H. AlDubayan, Eliezer M. Van Allen, Maria B. Baco, Francesca Khani, Jill P. Mesirov, Isaac J. Powell, Andrea Garofalo, Juan Miguel Mosquera, Coyin Oh, Stacey Gabriel, Pablo Tamayo, Alessandro Romanel, Brian D. Robinson, Samira Bahl, Anna Woloszynska-Read, Mark A. Rubin, Bokang Rabasha, Ali Amin-Mansour, Jeremy Chimene-Weiss, Karen S. Sfanos, Eejung Kim, Joseph R. Osborne, Francesca Demichelis
African-American men have the highest incidence of and mortality from prostate cancer. Whether a biological basis exists for this disparity remains unclear. Exome sequencing (n = 102) and targeted validation (n = 90) of localized primary hormone-naï
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef5c68f5f85b6bf53dbae421a5f00da
http://hdl.handle.net/11572/188562
http://hdl.handle.net/11572/188562
Autor:
Misop Han, Steven Stone, Todd Cohen, Bruce J. Trock, Tracy Jones, Igor Vidal, Saradha Rajamani, Alan W. Partin, Angelo M. De Marzo, Stephanie Glavaris
Publikováno v:
Journal of Clinical Oncology. 37:e16575-e16575
e16575 Background: To evaluate the cell cycle progression (CCP) score and PTEN as prognostic markers for risk of metastasis in a radical prostatectomy (RP) cohort of NCCN intermediate and high risk prostate cancer. Methods: This IRB-approved case-coh
Autor:
Helen Fedor, David Walker, David M. Esopi, Nkosi Adejola, Alan K. Meeker, Marc K. Halushka, Meltem Gürel, Srinivasan Yegnasubramanian, Jessica Hicks, William G. Nelson, Timothy Mosbruger, Christopher M. Heaphy, William B. Isaacs, Angelo M. De Marzo, Jonathan W. Simons, Michael C. Haffner
Publikováno v:
Journal of Clinical Investigation. 123:4918-4922
Recent controversies surrounding prostate cancer overtreatment emphasize the critical need to delineate the molecular features associated with progression to lethal metastatic disease. Here, we have used whole-genome sequencing and molecular patholog
Autor:
Berrak Gumuskaya, Angelo M. De Marzo, Jonathan I. Epstein, Brian D. Robinson, Tamara L. Lotan, Jessica Hicks, Tsuyoshi Iwata, Hameed A. Rahimi
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Intraductal carcinoma of the prostate is a marker of aggressive disease. However, intraductal carcinoma exists on a morphologic continuum with high grade prostatic intraepithelial carcinoma (PIN) and distinguishing intraductal carcinoma from PIN is a