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pro vyhledávání: '"Michael T. Williams"'
Publikováno v:
The Tools of Neuroscience Experiment ISBN: 9781003251392
The Tools of Neuroscience Experiment
The Tools of Neuroscience Experiment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::119ee58d90da974eb60b7db8f84501f2
https://doi.org/10.4324/9781003251392-5
https://doi.org/10.4324/9781003251392-5
Publikováno v:
Neurotoxicol Teratol
Developmental neurotoxicity (DNT) studies could benefit from revisions to study design, data analysis, and some behavioral test methods to enhance reproducibility. The Environmental Protection Agency (EPA) reviewed 69 studies submitted to the Office
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e5534733e0ed05488c8a6634431c8d
https://europepmc.org/articles/PMC8440477/
https://europepmc.org/articles/PMC8440477/
Autor:
Nina A. Atanasova, Matthew R. Skelton, Laurie L. Davenport, Michael T. Williams, Zuhair I. Abdulla, Charles V. Vorhees, Robyn M. Amos-Kroohs
Publikováno v:
Neurotoxicology and Teratology. 59:16-26
Manganese (Mn) is an essential element but neurotoxic at higher exposure levels. The effects of Mn overexposure (MnOE) on hippocampal and striatal-dependent learning and memory in rats were tested in combination with iron deficiency (FeD) and develop
Publikováno v:
Neurotoxicity Research. 31:269-282
Neonatal exposure to methamphetamine (MA) and developmental chronic stress significantly alter neurodevelopmental profiles that show a variety of long-term physiological and behavioral effects. In the current experiment, Sprague-Dawley rats were expo
Publikováno v:
Neurotoxicology and Teratology. 57:1-19
Advantageous maneuvering through the environment to find food and avoid or escape danger is central to survival of most animal species. The ability to do so depends on learning and remembering different locations, especially home-base. This capacity
Autor:
Michael T. Williams, Curtis E. Grace, Matthew R. Skelton, Robyn M. Amos-Kroohs, Devon L. Graham, Charles V. Vorhees, Tori L. Schaefer, Amanda A. Braun
Publikováno v:
NeuroToxicology. 54:22-33
The level of lead (Pb) exposure in children has decreased dramatically since restrictions on its use were implemented. However, even with restrictions, children are exposed to Pb and still present with cognitive and behavioral deficits. One prominent
Autor:
Charles V. Vorhees, Robyn M. Amos-Kroohs, Kerstin H. Lundgren, Amanda A. Braun, Kim B. Seroogy, Michael T. Williams, Arnold Gutierrez
Publikováno v:
Neurotoxicity Research. 30:199-212
The nucleus accumbens (Nacc) and medial prefrontal cortex (mPFC) receive dopaminergic innervation from the ventral tegmental area and are involved in learning. Male rats with 6-hydroxydopamine (6-OHDA)-induced dopaminergic and noradrenergic reduction
Publikováno v:
Neurotoxicology and Teratology. 52:93-108
Maneuvering safely through the environment is central to survival of all animals. The ability to do this depends on learning and remembering locations. This capacity is encoded in the brain by two systems: one using cues outside the organism (distal
Autor:
Kim B. Seroogy, Robyn M. Amos-Kroohs, Matthew R. Skelton, Charles V. Vorhees, Michael T. Williams, Kerstin H. Lundgren, Amanda A. Braun, Arnold Gutierrez
Publikováno v:
Neurobiology of Learning and Memory. 118:55-63
Both egocentric route-based learning and spatial learning, as assessed by the Cincinnati water maze (CWM) and Morris water maze (MWM), respectively, are impaired following an 80% dopamine (DA) loss in the neostriatum after 6-hydroxydopamine (6-OHDA)
Publikováno v:
Genes, Brain and Behavior.
Phosphodiesterase-1b (Pde1b) is highly expressed in striatum, dentate gyrus, CA3, and substantia nigra. In a new Floxed Pde1b x CreCMV global knock-out (KO) mouse model we show an immobility resistance phenotype that recapitulates that found in const