Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Graham K. Murray"'
Autor:
Uzma Zahid, Robert A. McCutcheon, Faith Borgan, Sameer Jauhar, Fiona Pepper, Matthew M. Nour, Maria Rogdaki, Martin Osugo, Graham K. Murray, Pamela Hathway, Robin M. Murray, Oliver D. Howes
Publikováno v:
Frontiers in Psychiatry
IntroductionGlutamatergic dysfunction is implicated in the pathophysiology of schizophrenia. It is unclear whether glutamatergic dysfunction predicts response to treatment or if antipsychotic treatment influences glutamate levels. We investigated the
Autor:
Robyn H, McCarron, Peter, Swann, Jonathon, Artingstall, Anne-Marie, Burn, Julia, Deakin, Fiona, Ellis, Praveen Kumar, Gandamaneni, Joannah, Griffith, Amanda, Ireland, Jim, Leadbetter, Joyce, Man, Simon, Mitchell, Asha, Praseedom, Ilyana, Rokkou, Clare, Rose, Ginny, Russell, Patricia, Worsnip, Graham K, Murray, Fiona, Thompson
Publikováno v:
Clinical Neuropsychiatry
Objective The COVID-19 pandemic has impacted community mental health, but the effect on psychiatric admissions is unknown. We investigated factors contributing to acute psychiatric admissions, and whether this changed during the first UK lockdown. Me
Autor:
Arnaud Cachia, Grégoire Borst, Renaud Jardri, Armin Raznahan, Graham K. Murray, Jean-François Mangin, Marion Plaze
Publikováno v:
Frontiers in Neuroanatomy
Frontiers in Neuroanatomy, Frontiers, 2021, 15, ⟨10.3389/fnana.2021.712862⟩
Frontiers in Neuroanatomy, 2021, 15, ⟨10.3389/fnana.2021.712862⟩
Frontiers in Neuroanatomy, Vol 15 (2021)
Frontiers in Neuroanatomy, Frontiers, 2021, 15, ⟨10.3389/fnana.2021.712862⟩
Frontiers in Neuroanatomy, 2021, 15, ⟨10.3389/fnana.2021.712862⟩
Frontiers in Neuroanatomy, Vol 15 (2021)
International audience; Growing evidence supports that prenatal processes play an important role for cognitive ability in normal and clinical conditions. In this context, several neuroimaging studies searched for features in postnatal life that could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6725b02773e23a51c05216a76950f689
https://hal.archives-ouvertes.fr/hal-03483497
https://hal.archives-ouvertes.fr/hal-03483497
Publikováno v:
Journal of Affective Disorders. 249:63-72
Background Maternal antenatal depression may alter offspring neurodevelopment, but long follow-up studies are lacking. We studied the risks for mood disorders and schizophrenia in adult offspring of antenatally depressed mothers, taking account paren
Autor:
Jehannine Austin, John J. McGrath, Graham K. Murray, Ian B. Hickie, Naomi R. Wray, Peter M. Visscher, Tian Lin
Publikováno v:
Wray, N R, Lin, T, Austin, J, McGrath, J J, Hickie, I B, Murray, G K & Visscher, P M 2021, ' From Basic Science to Clinical Application of Polygenic Risk Scores : A Primer ', JAMA Psychiatry, vol. 78, no. 1, pp. 101-109 . https://doi.org/10.1001/jamapsychiatry.2020.3049
Importance: Polygenic risk scores (PRS) are predictors of the genetic susceptibilities of individuals to diseases. All individuals have DNA risk variants for all common diseases, but genetic susceptibility differences between people reflect the cumul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41bbb9d226e0c2cf7ec37520193a01fb
https://pure.au.dk/portal/da/publications/from-basic-science-to-clinical-application-of-polygenic-risk-scores(41012481-22f1-4e5d-aac1-f89284b6e271).html
https://pure.au.dk/portal/da/publications/from-basic-science-to-clinical-application-of-polygenic-risk-scores(41012481-22f1-4e5d-aac1-f89284b6e271).html
In March 2020 the SARS-CoV-2infection (COVID-19) was declared a pandemic. In response to its world-wide outbreak radical measures were taken by governments across the world including curfew, quarantine, travel bans, social distancing, work place and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f64bfdf478045b5bf9741f6abdd964d
https://doi.org/10.1101/2020.08.27.20182980
https://doi.org/10.1101/2020.08.27.20182980
Autor:
Daniel J. Smith, Donald M. Lyall, Richard A. I. Bethlehem, Breda Cullen, Nicholas Graham, Graham K. Murray, Laura M. Lyall, Amy Ferguson, Joey Ward, Mark E.S. Bailey, Rona J. Strawbridge, Keira J.A. Johnston
Publikováno v:
Translational Psychiatry, Vol 9, Iss 1, Pp 1-9 (2019)
Ward, J, Lyall, L M, Bethlehem, R A I, Ferguson, A, Strawbridge, R J, Lyall, D M, Cullen, B, Graham, N, Johnston, K J A, Bailey, M E S, Murray, G K & Smith, D J 2019, ' Novel genome-wide associations for anhedonia, genetic correlation with psychiatric disorders, and polygenic association with brain structure ', Translational Psychiatry, vol. 9, no. 1, pp. 327 . https://doi.org/10.1038/s41398-019-0635-y
Translational Psychiatry
Ward, J, Lyall, L M, Bethlehem, R A I, Ferguson, A, Strawbridge, R J, Lyall, D M, Cullen, B, Graham, N, Johnston, K J A, Bailey, M E S, Murray, G K & Smith, D J 2019, ' Novel genome-wide associations for anhedonia, genetic correlation with psychiatric disorders, and polygenic association with brain structure ', Translational Psychiatry, vol. 9, no. 1, pp. 327 . https://doi.org/10.1038/s41398-019-0635-y
Translational Psychiatry
Anhedonia is a core feature of several psychiatric disorders but its biological underpinnings are poorly understood. We performed a genome-wide association study of anhedonia in 375,275 UK Biobank participants and assessed for genetic correlation bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ec28f1d0c8f0dcfc8b140debcbaf407
https://www.repository.cam.ac.uk/handle/1810/300684
https://www.repository.cam.ac.uk/handle/1810/300684
Publikováno v:
BJPsych Open
AimsThe COVID-19 pandemic has impacted community mental health, but the effect on psychiatric admissions is unknown. We investigated factors contributing to acute psychiatric admissions, and whether this changed during the first UK lockdown.MethodA r
Autor:
Solja Niemelä, Antti Mustonen, Jouko Miettunen, Graham K. Murray, John J. McGrath, Pirjo Mäki, James Scott, Tanja Nordström
Publikováno v:
Mustonen, A, Niemelä, S, McGrath, J J, Murray, G K, Nordström, T, Mäki, P, Miettunen, J & Scott, J G 2018, ' Adolescent inhalant use and psychosis risk-a prospective longitudinal study ', Schizophrenia Research, vol. 201, pp. 360-366 . https://doi.org/10.1016/j.schres.2018.05.013
BACKGROUND: Cross-sectional studies have suggested inhalant use is associated with psychosis. This association was examined in a longitudinal study accounting for other substance use and potential confounders.METHODS: We used a prospective sample (N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d22600317586de510d9f21f2c5dd14ec
https://www.repository.cam.ac.uk/handle/1810/285790
https://www.repository.cam.ac.uk/handle/1810/285790
Publikováno v:
Murray, G K, Lin, T, Austin, J, McGrath, J J, Hickie, I B & Wray, N R 2021, ' Could Polygenic Risk Scores Be Useful in Psychiatry? A Review ', JAMA Psychiatry, vol. 78, no. 2, pp. 210-219 . https://doi.org/10.1001/jamapsychiatry.2020.3042
Importance: Polygenic risk scores (PRS) are predictors of the genetic susceptibility to diseases, calculated for individuals as weighted counts of thousands of risk variants in which the risk variants and their weights have been identified in genome-