Zobrazeno 1 - 10
of 18
pro vyhledávání: '"James Travis"'
Publikováno v:
Microbial Pathogenesis. 32:173-181
Current consensus is that periodontitis is an infectious disease in which a deregulated chronic inflammatory reaction not only may lead to periodontal tissue damage but also eventually may cause tooth loss. In controlling the inflammatory state the i
Autor:
James Travis, Dennis A. Bagarozzi
Publikováno v:
Phytochemistry. 47:593-598
Extracts from ragweed pollen grains contain novel trypsin and chymotrypsin-like serine peptidases which are described in this report. The molecular mass of the chymotrypsin-like enzyme was 82 kDa, had a pH optimum near 9.0, and its activity was unaff
Publikováno v:
Journal of Biological Chemistry. 272:8250-8255
Destruction of components of the extracellular matrix of the lung by neutrophil elastase is believed to be a critical event in the development of obstructive lung disease. The local synthesis of alpha1-proteinase inhibitor, the controlling inhibitor
Publikováno v:
Ciba Foundation Symposium 75-Protein Degradation in Health and Disease
Two of the major enzymes present in an released from neutrophil granulocytes are the endoproteinases elastase and cathepsin G. While the former is believed to be one of the major causative agents responsible for tissue destruction in emphysema and rh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e0113c134e5ba4e7b35475b4525cc87
https://doi.org/10.1002/9780470720585.ch4
https://doi.org/10.1002/9780470720585.ch4
Autor:
Grzegorz Szmyd, Jonathan L. Moon, Agnieszka Banbula, Timothy J. Foster, Malgorzata Kubica, Ewa Golonka, Aneta Oleksy, Doron C. Greenbaum, Matthew Bogyo, James Travis, Jan Potempa
Publikováno v:
Biological chemistry. 385(6)
Staphylococcus epidermidis, a Gram-positive, coagu- lase-negative bacterium is a predominant inhabitant of human skin and mucous membranes. Recently, however, it has become one of the most important agents of hos- pital-acquired bacteriemia, as it ha
Autor:
Frank G. Oppenheim, Robert F. Troxler, James Travis, Heloisa Gusman, Jan Potempa, Eva J. Helmerhorst
One of the salient features of periodontitis and gingivitis is the increase in the levels of bacterial and host-derived proteolytic enzymes in oral inflammatory exudates. This study evaluated the potential of histatin 5, a 24-residue histidine-rich s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878e83a955504f55aa0c2e80e7269b7a
https://europepmc.org/articles/PMC98034/
https://europepmc.org/articles/PMC98034/
Autor:
Jan Potempa, James Travis
Publikováno v:
Biochimica et biophysica acta. 1477(1-2)
The emergence of bacterial pathogen resistance to common antibiotics strongly supports the necessity to develop alternative mechanisms for combating drug-resistant forms of these infective organisms. Currently, few pharmaceutical companies have attem
Autor:
Jan Potempa, Jan J. Enghild, Jowita Mikolajczyk-Pawlinska, James Travis, Ida B. Thøgersen, David Brassell, Daniel C. Nelson
Publikováno v:
Potempa, J, Mikolajczyk-Pawlinska, J, Brassell, D, Nelson, D, Thøgersen, I B, Enghild, J J & Travis, J 1998, ' Comparative properties of two cysteine proteinases (gingipains R), the products of two related but individual genes of Porphyromonas gingivalis ', Journal of Biological Chemistry, vol. 273, no. 34, pp. 21648-57 .
Udgivelsesdato: 1998-Aug-21 Proteolytic enzymes produced by Porphyromonas gingivalis are important virulence factors of this periodontopathogen. Two of these enzymes, referred to as arginine-specific cysteine proteinases (gingipains R), are the produ
Publikováno v:
American journal of respiratory cell and molecular biology. 18(3)
Ragweed (Ambrosia artemisiifolia) is clinically the most important source of seasonal aeroallergens, as it is responsible for the majority and most severe cases of hay fever (allergic rhinitis). Extracts from pollen grains have been shown to contain
Publikováno v:
Scopus-Elsevier
Porphyromonas gingivalis is one of the major pathogens associated with periodontal disease and releases powerful cysteine proteinases known as the gingipains, which are key virulence factors for this organism. The three forms of gingipains, gingipain