Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Stringham, Heather M"'
Autor:
Justice AE; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.; Weis Center for Research, Geisinger Health System, Danville, PA, USA., Karaderi T; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Biological Sciences, Faculty of Arts and Sciences, Eastern Mediterranean University, Famagusta, Cyprus., Highland HM; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Young KL; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Graff M; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Lu Y; Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN, USA.; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Turcot V; Montreal Heart Institute, Universite de Montreal, Montreal, Quebec, Canada., Auer PL; Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI, USA., Fine RS; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA., Guo X; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Schurmann C; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Lempradl A; Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany., Marouli E; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Winkler TW; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany., Locke AE; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; McDonnell Genome Institute, Washington University School of Medicine, Saint Louis, MO, USA., Medina-Gomez C; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Esko T; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA.; Estonian Genome Center, University of Tartu, Tartu, Estonia., Vedantam S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA., Giri A; Department of Obstetrics and Gynecology, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA., Lo KS; Montreal Heart Institute, Universite de Montreal, Montreal, Quebec, Canada.; Department of Obstetrics and Gynecology, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA., Alfred T; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Mudgal P; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA., Ng MCY; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA., Heard-Costa NL; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; NHLBI Framingham Heart Study, Framingham, MA, USA., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Manning AK; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Harvard University Medical School, Boston, MA, USA.; Massachusetts General Hospital, Boston, MA, USA., Willems SM; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Sivapalaratnam S; Massachusetts General Hospital, Boston, MA, USA.; Department of Vascular Medicine, AMC, Amsterdam, The Netherlands.; Department of Haematology, University of Cambridge, Cambridge, UK., Abecasis G; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; School of Public Health, University of Michigan, Ann Arbor, MI, USA., Alam DS; School of Kinesiology and Health Science, Faculty of Health, York University, Toronto, Canada., Allison M; Department of Family Medicine & Public Health, University of California, San Diego, La Jolla, CA, USA., Amouyel P; INSERM U1167, Lille, France.; Institut Pasteur de Lille, U1167, Lille, France.; U1167-RID-AGE, Universite de Lille - Risk factors and molecular determinants of aging-related diseases, Lille, France., Arzumanyan Z; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Balkau B; INSERM U1018, Centre de recherche en Épidemiologie et Sante des Populations (CESP), Villejuif, France., Bastarache L; Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA., Bergmann S; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Blüher M; IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Boeing H; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Böger CA; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Bork-Jensen J; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Bowden DW; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Brandslund I; Department of Clinical Biochemistry, Lillebaelt Hospital, Vejle, Denmark.; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark., Broer L; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Burt AA; Department of Medicine (Medical Genetics), University of Washington, Seattle, WA, USA., Butterworth AS; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Caulfield MJ; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Research Centre, Barts and The London School of Medicine & Dentistry, Queen Mary University of London, London, UK., Cesana G; Research Centre on Public Health, University of Milano-Bicocca, Monza, Italy., Chambers JC; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Department of Cardiology, London North West Healthcare NHS Trust, Ealing Hospital, Middlesex, UK.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK., Chasman DI; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Division of Preventive Medicine, Brigham and Women's and Harvard Medical School, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Chen YI; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Chowdhury R; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Christensen C; Medical department, Lillebaelt Hospital, Vejle, Denmark., Chu AY; Division of Preventive Medicine, Brigham and Women's and Harvard Medical School, Boston, MA, USA., Collins FS; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Cook JP; Department of Biostatistics, University of Liverpool, Liverpool, UK., Cox AJ; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Menzies Health Institute Queensland, Griffith University, Southport, Queensland, Australia., Crosslin DS; Department of Biomedical Infomatics and Medical Education, University of Washington, Seattle, WA, USA., Danesh J; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Wellcome Trust Sanger Institute, Hinxton, UK.; British Heart Foundation Cambridge Centre of Excellence, Department of Medicine, University of Cambridge, Cambridge, UK., de Bakker PIW; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.; Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Denus S; Montreal Heart Institute, Universite de Montreal, Montreal, Quebec, Canada.; Faculty of Pharmacy, Universite de Montreal, Montreal, Quebec, Canada., Mutsert R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Dedoussis G; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece., Demerath EW; Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Dennis JG; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Denny JC; Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA., Di Angelantonio E; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Cambridge Centre of Excellence, Department of Medicine, University of Cambridge, Cambridge, UK., Dörr M; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Drenos F; Institute of Cardiovascular Science, University College London, London, UK.; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK.; Department of Life Sciences, Brunel University London, Uxbridge, UK., Dubé MP; Montreal Heart Institute, Universite de Montreal, Montreal, Quebec, Canada.; Department of Medicine, Faculty of Medicine, Universite de Montreal, Montreal, Quebec, Canada., Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Elliott P; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Evangelou E; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Farmaki AE; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece., Feng S; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Ferrannini E; CNR Institute of Clinical Physiology, Pisa, Italy.; Department of Clinical & Experimental Medicine, University of Pisa, Pisa, Italy., Ferrieres J; Toulouse University School of Medicine, Toulouse, France., Florez JC; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Harvard University Medical School, Boston, MA, USA.; Massachusetts General Hospital, Boston, MA, USA., Fornage M; Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Fox CS; NHLBI Framingham Heart Study, Framingham, MA, USA., Franks PW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmo, Sweden.; Department of Nutrition, Harvard School of Public Health, Boston, MA, USA.; Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå, Sweden., Friedrich N; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany., Gan W; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Gandin I; Ilaria Gandin, Research Unit, AREA Science Park, Trieste, Italy., Gasparini P; Department of Medical Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health-IRCCS Burlo Garofolo, Trieste, Italy., Giedraitis V; Geriatrics, Department of Public Health, Uppsala University, Uppsala, Sweden., Girotto G; Department of Medical Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health-IRCCS Burlo Garofolo, Trieste, Italy., Gorski M; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Grallert H; German Center for Diabetes Research, München-Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Grarup N; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Grove ML; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Gustafsson S; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Haessler J; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle WA, USA., Hansen T; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Hattersley AT; University of Exeter Medical School, University of Exeter, Exeter, UK., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Heid IM; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Holmen OL; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, NTNU, Norwegian University of Science and Technology, Trondheim, Norway., Hovingh GK; Department of Vascular Medicine, AMC, Amsterdam, The Netherlands., Howson JMM; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Hu Y; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China., Hung YJ; Division of Endocrinology and Metabolism, Department of Internal Medicine, Tri-Service General Hospital Songshan Branch, Taipei, Taiwan.; School of Medicine, National Defense Medical Center, Taipei, Taiwan., Hveem K; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; HUNT Research Center, Department of Public Health, Norwegian University of Science and Technology, Levanger, Norway., Ikram MA; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands., Ingelsson E; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Stanford Cardiovascular Institute, Stanford University, Stanford, CA, USA., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Jarvik GP; Department of Medicine (Medical Genetics), University of Washington, Seattle, WA, USA.; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Jia Y; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Jørgensen T; Faculty of Medicine, Aalborg University, Aalborg, Denmark.; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Research Center for Prevention and Health, Capital Region of Denmark, Glostrup, Denmark., Jousilahti P; National Institute for Health and Welfare, Helsinki, Finland., Justesen JM; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Kahali B; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; Division of Gastroenterology, University of Michigan, Ann Arbor, MI, USA.; Centre for Brain Research, Indian Institute of Science, Bangalore, India., Karaleftheri M; Echinos Medical Centre, Echinos, Greece., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Karpe F; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Kee F; UKCRC Centre of Excellence for Public Health Research, Queens University Belfast, Belfast, UK., Kitajima H; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Komulainen P; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Kooner JS; Department of Cardiology, London North West Healthcare NHS Trust, Ealing Hospital, Middlesex, UK.; Imperial College Healthcare NHS Trust, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.; National Heart and Lung Institute, Imperial College London, Hammersmith Hospital Campus, London, UK., Kovacs P; IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany., Krämer BK; University Medical Centre Mannheim, 5th Medical Department, University of Heidelberg, Mannheim, Germany., Kuulasmaa K; National Institute for Health and Welfare, Helsinki, Finland., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Lakka TA; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Lamparter D; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Verge Genomics, San Fransico, CA, USA., Lange LA; Division of Biomedical and Personalized Medicine, Department of Medicine, University of Colorado-Denver, Aurora, CO, USA., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Larson EB; Department of Medicine (Medical Genetics), University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.; Department of Health Services, University of Washington, Seattle, WA, USA., Lee NR; Department of Anthropology, Sociology, and History, University of San Carlos, Cebu City, Philippines.; USC-Office of Population Studies Foundation, Inc., University of San Carlos, Cebu City, Philippines., Lee WJ; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.; Department of Social Work, Tunghai University, Taichung, Taiwan., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Lewis CE; Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Li H; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China., Li J; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Palo Alto, CA, USA., Li-Gao R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Lin LA; Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Lin X; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China., Lind L; Uppsala University, Uppsala, Sweden., Lindström J; National Institute for Health and Welfare, Helsinki, Finland., Linneberg A; Research Center for Prevention and Health, Capital Region of Denmark, Glostrup, Denmark.; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Liu DJ; Department of Public Health Sciences, Institute for Personalized Medicine, The Pennsylvania State University College of Medicine, Hershey, PA, USA., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., MacGregor S; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Mägi R; Estonian Genome Center, University of Tartu, Tartu, Estonia., Männistö S; National Institute for Health and Welfare, Helsinki, Finland., Marenne G; Wellcome Trust Sanger Institute, Hinxton, UK., Marten J; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Masca NGD; Department of Cardiovascular Sciences, Univeristy of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK., McCarthy MI; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Meidtner K; German Center for Diabetes Research, München-Neuherberg, Germany.; Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany., Mihailov E; Estonian Genome Center, University of Tartu, Tartu, Estonia., Moilanen L; Department of Medicine, Kuopio University Hospital, Kuopio, Finland., Moitry M; Department of Epidemiology and Public Health, University of Strasbourg, Strasbourg, France.; Department of Public Health, University Hospital of Strasbourg, Strasbourg, France., Mook-Kanamori DO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands., Morgan A; Department of Medical Sciences, University of Trieste, Trieste, Italy., Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Biostatistics, University of Liverpool, Liverpool, UK., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universitat, Munich, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany., Munroe PB; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Research Centre, Barts and The London School of Medicine & Dentistry, Queen Mary University of London, London, UK., Narisu N; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Nelson CP; Department of Cardiovascular Sciences, Univeristy of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK., Neville M; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Ntalla I; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., O'Connell JR; Program for Personalized and Genomic Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Owen KR; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Pedersen O; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Peloso GM; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Pennell CE; Division of Obstetric and Gynaecology, School of Medicine, The University of Western Australia, Perth, Western Australia, Australia.; School of Medicine and Public Health, Faculty of Medicine and Health, The University of Newcastle, Newcastle, New South Wales, Australia., Perola M; National Institute for Health and Welfare, Helsinki, Finland.; Institute for Molecular Medicine (FIMM) and Diabetes and Obesity Research Program, University of Helsinki, Helsinki, Finland., Perry JA; Program for Personalized and Genomic Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Perry JRB; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Pers TH; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Ewing A; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Polasek O; School of Medicine, University of Split, Split, Croatia.; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Rasheed A; Centre for Non-Communicable Diseases, Karachi, Pakistan., Raulerson CK; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Rauramaa R; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Finland., Reilly DF; Genetics and Pharmacogenomics, Merck & Co., Inc., Boston, MA, USA., Reiner AP; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA., Ridker PM; Division of Preventive Medicine, Brigham and Women's and Harvard Medical School, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Rivas MA; Department of Biomedical Data Science, Stanford University, Stanford, CA, USA., Robertson NR; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Robino A; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Ruth KS; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Saleheen D; Centre for Non-Communicable Diseases, Karachi, Pakistan.; Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Salomaa V; National Institute for Health and Welfare, Helsinki, Finland., Samani NJ; Department of Cardiovascular Sciences, Univeristy of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK., Schreiner PJ; Division of Epidemiology & Community Health, University of Minnesota, Minneapolis, MN, USA., Schulze MB; German Center for Diabetes Research, München-Neuherberg, Germany.; Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany., Scott RA; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Segura-Lepe M; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Sim X; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; Saw Swee Hock School of Public Health, National University Health System, National University of Singapore, Singapore, Singapore., Slater AJ; Genetics, Target Sciences, GlaxoSmithKline, Research Triangle Park, NC, USA.; OmicSoft a QIAGEN Company, Cary, NC, USA., Small KS; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Smith BH; Division of Population Health Sciences, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK., Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Southam L; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Wellcome Trust Sanger Institute, Hinxton, UK., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Speliotes EK; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; Division of Gastroenterology, University of Michigan, Ann Arbor, MI, USA., Stefansson K; deCODE Genetics/Amgen Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Steinthorsdottir V; deCODE Genetics/Amgen Inc., Reykjavik, Iceland., Stirrups KE; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Chair of Genetic Epidemiology, IBE, Faculty of Medicine, LMU Munich, Germany., Stringham HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Stumvoll M; IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Sun L; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China., Surendran P; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Swart KMA; Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands., Tardif JC; Montreal Heart Institute, Universite de Montreal, Montreal, Quebec, Canada.; Department of Medicine, Faculty of Medicine, Universite de Montreal, Montreal, Quebec, Canada., Taylor KD; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Teumer A; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Thompson DJ; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Thorleifsson G; deCODE Genetics/Amgen Inc., Reykjavik, Iceland., Thorsteinsdottir U; deCODE Genetics/Amgen Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Thuesen BH; Research Center for Prevention and Health, Capital Region of Denmark, Glostrup, Denmark., Tönjes A; Center for Pediatric Research, Department for Women's and Child Health, University of Leipzig, Leipzig, Germany., Torres M; USC Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA., Tsafantakis E; Anogia Medical Centre, Anogia, Greece., Tuomilehto J; National Institute for Health and Welfare, Helsinki, Finland.; Centre for Vascular Prevention, Danube-University Krems, Krems, Austria.; Dasman Diabetes Institute, Dasman, Kuwait.; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Uitterlinden AG; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Uusitupa M; Department of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland., van Duijn CM; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands., Vanhala M; Central Finland Central Hospital, Jyvaskyla, Finland.; University of Eastern Finland, Kuopio, Finland., Varma R; USC Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA., Vermeulen SH; Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands., Vestergaard H; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Steno Diabetes Center Copenhagen, Gentofte, Denmark., Vitart V; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Vogt TF; Cardiometabolic Disease, Merck & Co., Inc., Kenilworth, NJ, USA., Vuckovic D; Department of Medical Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health-IRCCS Burlo Garofolo, Trieste, Italy., Wagenknecht LE; Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA., Walker M; Institute of Cellular Medicine, The Medical School, Newcastle University, Newcastle, UK., Wallentin L; Department of Medical Sciences, Cardiology, Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden., Wang F; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China., Wang CA; Division of Obstetric and Gynaecology, School of Medicine, The University of Western Australia, Perth, Western Australia, Australia.; School of Medicine and Public Health, Faculty of Medicine and Health, The University of Newcastle, Newcastle, New South Wales, Australia., Wang S; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Warren HR; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Research Centre, Barts and The London School of Medicine & Dentistry, Queen Mary University of London, London, UK., Waterworth DM; Genetics, Target Sciences, GlaxoSmithKline, Collegeville, PA, USA., Wessel J; Departments of Epidemiology & Medicine, Diabetes Translational Research Center, Fairbanks School of Public Health & School of Medicine, Indiana University, Indiana, IN, USA., White HD; Green Lane Cardiovascular Service, Auckland City Hospital and University of Auckland, Auckland, New Zealand., Willer CJ; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA., Wood AR; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Wu Y; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Yaghootkar H; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Yao J; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Yerges-Armstrong LM; Program for Personalized and Genomic Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; GlaxoSmithKline, King of Prussia, PA, USA., Young R; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; University of Glasgow, Glasgow, UK., Zeggini E; Wellcome Trust Sanger Institute, Hinxton, UK., Zhan X; Department of Clinical Sciences, Quantitative Biomedical Research Center, Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX, USA., Zhang W; Department of Cardiology, London North West Healthcare NHS Trust, Ealing Hospital, Middlesex, UK.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Zhao JH; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Zhao W; Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Zheng H; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China., Zhou W; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Zillikens MC; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Rivadeneira F; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Borecki IB; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Pospisilik JA; Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany., Deloukas P; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Lettre G; Montreal Heart Institute, Universite de Montreal, Montreal, Quebec, Canada.; Department of Medicine, Faculty of Medicine, Universite de Montreal, Montreal, Quebec, Canada., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Rotter JI; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Kutalik Z; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland., Hirschhorn JN; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA.; Departments of Pediatrics and Genetics, Harvard Medical School, Boston, MA, USA., Cupples LA; NHLBI Framingham Heart Study, Framingham, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., North KE; Department of Epidemiology and Carolina Center of Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. kari_north@unc.edu., Lindgren CM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. celi@well.ox.ac.uk.; Li Ka Shing Centre for Health Information and Discovery, The Big Data Institute, University of Oxford, Oxford, UK. celi@well.ox.ac.uk.
Publikováno v:
Nature genetics [Nat Genet] 2019 Mar; Vol. 51 (3), pp. 452-469. Date of Electronic Publication: 2019 Feb 18.
Autor:
Li S; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America., Mukherjee B, Taylor JM, Rice KM, Wen X, Rice JD, Stringham HM, Boehnke M
Publikováno v:
Genetic epidemiology [Genet Epidemiol] 2014 Jul; Vol. 38 (5), pp. 416-29. Date of Electronic Publication: 2014 May 06.
Autor:
Kilpeläinen TO; Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom., Qi L, Brage S, Sharp SJ, Sonestedt E, Demerath E, Ahmad T, Mora S, Kaakinen M, Sandholt CH, Holzapfel C, Autenrieth CS, Hyppönen E, Cauchi S, He M, Kutalik Z, Kumari M, Stančáková A, Meidtner K, Balkau B, Tan JT, Mangino M, Timpson NJ, Song Y, Zillikens MC, Jablonski KA, Garcia ME, Johansson S, Bragg-Gresham JL, Wu Y, van Vliet-Ostaptchouk JV, Onland-Moret NC, Zimmermann E, Rivera NV, Tanaka T, Stringham HM, Silbernagel G, Kanoni S, Feitosa MF, Snitker S, Ruiz JR, Metter J, Larrad MT, Atalay M, Hakanen M, Amin N, Cavalcanti-Proença C, Grøntved A, Hallmans G, Jansson JO, Kuusisto J, Kähönen M, Lutsey PL, Nolan JJ, Palla L, Pedersen O, Pérusse L, Renström F, Scott RA, Shungin D, Sovio U, Tammelin TH, Rönnemaa T, Lakka TA, Uusitupa M, Rios MS, Ferrucci L, Bouchard C, Meirhaeghe A, Fu M, Walker M, Borecki IB, Dedoussis GV, Fritsche A, Ohlsson C, Boehnke M, Bandinelli S, van Duijn CM, Ebrahim S, Lawlor DA, Gudnason V, Harris TB, Sørensen TI, Mohlke KL, Hofman A, Uitterlinden AG, Tuomilehto J, Lehtimäki T, Raitakari O, Isomaa B, Njølstad PR, Florez JC, Liu S, Ness A, Spector TD, Tai ES, Froguel P, Boeing H, Laakso M, Marmot M, Bergmann S, Power C, Khaw KT, Chasman D, Ridker P, Hansen T, Monda KL, Illig T, Järvelin MR, Wareham NJ, Hu FB, Groop LC, Orho-Melander M, Ekelund U, Franks PW, Loos RJ
Publikováno v:
PLoS medicine [PLoS Med] 2011 Nov; Vol. 8 (11), pp. e1001116. Date of Electronic Publication: 2011 Nov 01.
Autor:
Davis, James P., Huyghe, Jeroen R., Locke, Adam E., Jackson, Anne U., Sim, Xueling, Stringham, Heather M., Teslovich, Tanya M., Welch, Ryan P., Fuchsberger, Christian, Narisu, Narisu, Chines, Peter S., Kangas, Antti J., Soininen, Pasi, Ala-Korpela, Mika, Kuusisto, Johanna, Collins, Francis S., Laakso, Markku, Boehnke, Michael, Mohlke, Karen L.
Publikováno v:
PLoS Genetics; 10/30/2017, Vol. 13 Issue 10, p1-21, 21p
Autor:
Newton-Cheh, Christopher, Johnson, Toby, Gateva, Vesela, Tobin, Martin D, Bochud, Murielle, Coin, Lachlan, Najjar, Samer S, Zhao, Jing Hua, Heath, Simon C, Eyheramendy, Susana, Papadakis, Konstantinos, Voight, Benjamin F, Scott, Laura J, Zhang, Feng, Farrall, Martin, Tanaka, Toshiko, Wallace, Chris, Chambers, John C, Khaw, Kay-Tee, Nilsson, Peter, van der Harst, Pim, Polidoro, Silvia, Grobbee, Diederick E, Onland-Moret, N Charlotte, Bots, Michiel L, Wain, Louise V, Elliott, Katherine S, Teumer, Alexander, Luan, Jian'an, Lucas, Gavin, Kuusisto, Johanna, Burton, Paul R, Hadley, David, McArdle, Wendy L, Wellcome Trust Case Control Consortium, Brown, Morris, Dominiczak, Anna, Newhouse, Stephen J, Samani, Nilesh J, Webster, John, Zeggini, Eleftheria, Beckmann, Jacques S, Bergmann, Sven, Lim, Noha, Song, Kijoung, Vollenweider, Peter, Waeber, Gerard, Waterworth, Dawn M, Yuan, Xin, Groop, Leif, Orho-Melander, Marju, Allione, Alessandra, Di Gregorio, Alessandra, Guarrera, Simonetta, Panico, Salvatore, Ricceri, Fulvio, Romanazzi, Valeria, Sacerdote, Carlotta, Vineis, Paolo, Barroso, Inês, Sandhu, Manjinder S, Luben, Robert N, Crawford, Gabriel J, Jousilahti, Pekka, Perola, Markus, Boehnke, Michael, Bonnycastle, Lori L, Collins, Francis S, Jackson, Anne U, Mohlke, Karen L, Stringham, Heather M, Valle, Timo T, Willer, Cristen J, Bergman, Richard N, Morken, Mario A, Döring, Angela, Gieger, Christian, Illig, Thomas, Meitinger, Thomas, Org, Elin, Pfeufer, Arne, Wichmann, H Erich, Kathiresan, Sekar, Marrugat, Jaume, O'Donnell, Christopher J, Schwartz, Stephen M, Siscovick, David S, Subirana, Isaac, Freimer, Nelson B, Hartikainen, Anna-Liisa, McCarthy, Mark I, O'Reilly, Paul F, Peltonen, Leena, Pouta, Anneli, de Jong, Paul E, Snieder, Harold, van Gilst, Wiek H, Clarke, Robert, Goel, Anuj
Publikováno v:
Nature genetics, vol 41, iss 6
Elevated blood pressure is a common, heritable cause of cardiovascular disease worldwide. To date, identification of common genetic variants influencing blood pressure has proven challenging. We tested 2.5 million genotyped and imputed SNPs for assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::da71cb03b70b5657cef9b7a4175ce1d0
https://escholarship.org/uc/item/4xk0g9nn
https://escholarship.org/uc/item/4xk0g9nn
Autor:
Justice, Anne E, Karaderi, Tugce, Highland, Heather M, Young, Kristin L, Graff, Mariaelisa, Lu, Yingchang, Turcot, Valérie, Auer, Paul L, Fine, Rebecca S, Guo, Xiuqing, Schurmann, Claudia, Lempradl, Adelheid, Marouli, Eirini, Mahajan, Anubha, Winkler, Thomas W, Locke, Adam E, Medina-Gomez, Carolina, Esko, Tõnu, Vedantam, Sailaja, Giri, Ayush, Lo, Ken Sin, Alfred, Tamuno, Mudgal, Poorva, Ng, Maggie CY, Heard-Costa, Nancy L, Feitosa, Mary F, Manning, Alisa K, Willems, Sara M, Sivapalaratnam, Suthesh, Abecasis, Goncalo, Alam, Dewan S, Allison, Matthew, Amouyel, Philippe, Arzumanyan, Zorayr, Balkau, Beverley, Bastarache, Lisa, Bergmann, Sven, Bielak, Lawrence F, Blüher, Matthias, Boehnke, Michael, Boeing, Heiner, Boerwinkle, Eric, Böger, Carsten A, Bork-Jensen, Jette, Bottinger, Erwin P, Bowden, Donald W, Brandslund, Ivan, Broer, Linda, Burt, Amber A, Butterworth, Adam S, Caulfield, Mark J, Cesana, Giancarlo, Chambers, John C, Chasman, Daniel I, Chen, Yii-Der Ida, Chowdhury, Rajiv, Christensen, Cramer, Chu, Audrey Y, Collins, Francis S, Cook, James P, Cox, Amanda J, Crosslin, David S, Danesh, John, de Bakker, Paul IW, Denus, Simon de, Mutsert, Renée de, Dedoussis, George, Demerath, Ellen W, Dennis, Joe G, Denny, Josh C, Angelantonio, Emanuele Di, Dörr, Marcus, Drenos, Fotios, Dubé, Marie-Pierre, Dunning, Alison M, Easton, Douglas F, Elliott, Paul, Evangelou, Evangelos, Farmaki, Aliki-Eleni, Feng, Shuang, Ferrannini, Ele, Ferrieres, Jean, Florez, Jose C, Fornage, Myriam, Fox, Caroline S, Franks, Paul W, Friedrich, Nele, Gan, Wei, Gandin, Ilaria, Gasparini, Paolo, Giedraitis, Vilmantas, Girotto, Giorgia, Gorski, Mathias, Grallert, Harald, Grarup, Niels, Grove, Megan L, Gustafsson, Stefan, Haessler, Jeff, Hansen, Torben, Hattersley, Andrew T, Hayward, Caroline, Heid, Iris M, Holmen, Oddgeir L, Hovingh, G Kees, Howson, Joanna MM, Hu, Yao, Hung, Yi-Jen, Hveem, Kristian, Ikram, M Arfan, Ingelsson, Erik, Jackson, Anne U, Jarvik, Gail P, Jia, Yucheng, Jørgensen, Torben, Jousilahti, Pekka, Justesen, Johanne M, Kahali, Bratati, Karaleftheri, Maria, Kardia, Sharon LR, Karpe, Fredrik, Kee, Frank, Kitajima, Hidetoshi, Komulainen, Pirjo, Kooner, Jaspal S, Kovacs, Peter, Krämer, Bernhard K, Kuulasmaa, Kari, Kuusisto, Johanna, Laakso, Markku, Lakka, Timo A, Lamparter, David, Lange, Leslie A, Langenberg, Claudia, Larson, Eric B, Lee, Nanette R, Lee, Wen-Jane, Lehtimäki, Terho, Lewis, Cora E, Li, Huaixing, Li, Jin, Li-Gao, Ruifang, Lin, Li-An, Lin, Xu, Lind, Lars, Lindström, Jaana, Linneberg, Allan, Liu, Ching-Ti, Liu, Dajiang J, Luan, Jian'an, Lyytikäinen, Leo-Pekka, MacGregor, Stuart, Mägi, Reedik, Männistö, Satu, Marenne, Gaëlle, Marten, Jonathan, Masca, Nicholas GD, McCarthy, Mark I, Meidtner, Karina, Mihailov, Evelin, Moilanen, Leena, Moitry, Marie, Mook-Kanamori, Dennis O, Morgan, Anna, Morris, Andrew P, Müller-Nurasyid, Martina, Munroe, Patricia B, Narisu, Narisu, Nelson, Christopher P, Neville, Matt, Ntalla, Ioanna, O'Connell, Jeffrey R, Owen, Katharine R, Pedersen, Oluf, Peloso, Gina M, Pennell, Craig E, Perola, Markus, Perry, James A, Perry, John RB, Pers, Tune H, Ewing, Ailith, Polasek, Ozren, Raitakari, Olli T, Rasheed, Asif, Raulerson, Chelsea K, Rauramaa, Rainer, Reilly, Dermot F, Reiner, Alex P, Ridker, Paul M, Rivas, Manuel A, Robertson, Neil R, Robino, Antonietta, Rudan, Igor, Ruth, Katherine S, Saleheen, Danish, Salomaa, Veikko, Samani, Nilesh J, Schreiner, Pamela J, Schulze, Matthias B, Scott, Robert A, Segura-Lepe, Marcelo, Sim, Xueling, Slater, Andrew J, Small, Kerrin S, Smith, Blair H, Smith, Jennifer A, Southam, Lorraine, Spector, Timothy D, Speliotes, Elizabeth K, Stefansson, Kari, Steinthorsdottir, Valgerdur, Stirrups, Kathleen E, Strauch, Konstantin, Stringham, Heather M, Stumvoll, Michael, Sun, Liang, Surendran, Praveen, Swart, Karin MA, Tardif, Jean-Claude, Taylor, Kent D, Teumer, Alexander, Thompson, Deborah J, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Thuesen, Betina H, Tönjes, Anke, Torres, Mina, Tsafantakis, Emmanouil, Tuomilehto, Jaakko, Uitterlinden, André G, Uusitupa, Matti, van Duijn, Cornelia M, Vanhala, Mauno, Varma, Rohit, Vermeulen, Sita H, Vestergaard, Henrik, Vitart, Veronique, Vogt, Thomas F, Vuckovic, Dragana, Wagenknecht, Lynne E, Walker, Mark, Wallentin, Lars, Wang, Feijie, Wang, Carol A, Wang, Shuai, Wareham, Nicholas J, Warren, Helen R, Waterworth, Dawn M, Wessel, Jennifer, White, Harvey D, Willer, Cristen J, Wilson, James G, Wood, Andrew R, Wu, Ying, Yaghootkar, Hanieh, Yao, Jie, Yerges-Armstrong, Laura M, Young, Robin, Zeggini, Eleftheria, Zhan, Xiaowei, Zhang, Weihua, Zhao, Jing Hua, Zhao, Wei, Zheng, He, Zhou, Wei, Zillikens, M Carola, CHD Exome+ Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology (CH, EPIC-CVD Consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, InterAct, ReproGen Consortium, T2D-Genes Consortium, MAGIC Investigators, Rivadeneira, Fernando, Borecki, Ingrid B, Pospisilik, J Andrew, Deloukas, Panos, Frayling, Timothy M, Lettre, Guillaume, Mohlke, Karen L, Rotter, Jerome I, Kutalik, Zoltán, Hirschhorn, Joel N, Cupples, L Adrienne, Loos, Ruth JF, North, Kari E, Lindgren, Cecilia M
Publikováno v:
Nature Genetics, 51, 3, pp. 452-469
Nature Genetics, 51, 452-469
Nature genetics, 51(3), 452-469. Nature Publishing Group
Nature Genetics
Nature genetics
Nature Genetics, 51(3), 452-469. Nature Publishing Group
Nature genetics, vol. 51, no. 3, pp. 452-469
Nat. Genet. 51, 452–469 (2019)
Justice, A E, Karaderi, T, Highland, H M, Young, K L, Graff, M, Lu, Y, Turcot, V, Auer, P L, Fine, R S, Guo, X, Schurmann, C, Lempradl, A, Marouli, E, Mahajan, A, Winkler, T W, Locke, A E, Medina-Gomez, C, Esko, T N, Vedantam, S, Giri, A, Lo, K S, Alfred, T, Mudgal, P, Ng, M C Y, Heard-Costa, N L, Feitosa, M F, Manning, A K, Willems, S M, Sivapalaratnam, S, Abecasis, G, Alam, D S, Allison, M, Amouyel, P, Arzumanyan, Z, Balkau, B, Bastarache, L, Bergmann, S, Bielak, L F, Blüher, M, Boehnke, M, Boeing, H, Boerwinkle, E, Böger, C A, Bork-Jensen, J, Bottinger, E P, Bowden, D W, Brandslund, I, Li, J, Swart, K M A, Vermeulen, S H, CHD Exome+ Consortium, Frayling, T M, Lettre, G, Mohlke, K L, Rotter, J I, Kutalik, Z, Hirschhorn, J N, Cupples, L A, Loos, R J F, North, K E & Lindgren, C M 2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution ', Nature Genetics, vol. 51, pp. 452–469 . https://doi.org/10.1038/s41588-018-0334-2
Justice, A E, Karaderi, T, Highland, H M, Young, K L, Graff, M, Lu, Y, Turcot, V, Auer, P L, Fine, R S, Guo, X, Schurmann, C, Lempradl, A, Marouli, E, Mahajan, A, Winkler, T W, Locke, A E, Medina-Gomez, C, Esko, T, Vedantam, S, Giri, A, Lo, K S, Alfred, T, Mudgal, P, Ng, M C Y, Heard-Costa, N L, Feitosa, M F, Manning, A K, Willems, S M, Sivapalaratnam, S, Abecasis, G, Alam, D S, Allison, M, Amouyel, P, Arzumanyan, Z, Balkau, B, Bastarache, L, Bergmann, S, Bielak, L F, Blüher, M, Boehnke, M, Boeing, H, Boerwinkle, E, Böger, C A, Bork-Jensen, J, Bottinger, E P, Bowden, D W, Brandslund, I, Broer, L, Burt, A A, Butterworth, A S, Caulfield, M J, Cesana, G, Chambers, J C, Chasman, D I, Chen, Y-D I, Chowdhury, R, Christensen, C, Chu, A Y, Collins, F S, Cook, J P, Cox, A J, Crosslin, D S, Danesh, J, de Bakker, P I W, de Denus, S, de Mutsert, R, Dedoussis, G, Demerath, E W, Dennis, J G, Denny, J C, Di Angelantonio, E, Dörr, M, Drenos, F, Dubé, M-P, Dunning, A M, Easton, D F, Elliott, P, Evangelou, E, Farmaki, A-E, Feng, S, Ferrannini, E, Ferrieres, J, Florez, J C, Fornage, M, Fox, C S, Franks, P W, Friedrich, N, Gan, W, Gandin, I, Gasparini, P, Giedraitis, V, Girotto, G, Gorski, M, Grallert, H, Grarup, N, Grove, M L, Gustafsson, S, Haessler, J, Hansen, T, Hattersley, A T, Hayward, C, Heid, I M, Holmen, O L, Kees Hovingh, G, Howson, J M M, Hu, Y, Hung, Y-J, Hveem, K, Ikram, M A, Ingelsson, E, Jackson, A U, Jarvik, G P, Jia, Y, Jørgensen, T, Jousilahti, P, Justesen, J M, Kahali, B, Karaleftheri, M, Kardia, S L R, Karpe, F, Kee, F, Kitajima, H, Komulainen, P, Kooner, J S, Kovacs, P, Krämer, B K, Kuulasmaa, K, Kuusisto, J, Laakso, M, Lakka, T A, Lamparter, D, Lange, L A, Langenberg, C, Larson, E B, Lee, N R, Lee, W-J, Lehtimäki, T, Lewis, C E, Li, H, Li, J, Li-Gao, R, Lin, L-A, Lin, X, Lind, L, Lindström, J, Linneberg, A, Liu, C-T, Liu, D J, Luan, J, Lyytikäinen, L-P, MacGregor, S, Mägi, R, Männistö, S, Marenne, G, Marten, J, Masca, N G D, McCarthy, M I, Meidtner, K, Mihailov, E, Moilanen, L, Moitry, M, Mook-Kanamori, D O, Morgan, A, Morris, A P, Müller-Nurasyid, M, Munroe, P B, Narisu, N, Nelson, C P, Neville, M, Ntalla, I, Owen, K R, O'Connell, J R, Pedersen, O, Peloso, G M, Pennell, C E, Perola, M, Perry, J A, Perry, J R B, Pers, T H, Ewing, A, Polasek, O, Raitakari, O T, Rasheed, A, Raulerson, C K, Rauramaa, R, Reilly, D F, Reiner, A P, Ridker, P M, Rivas, M A, Robertson, N R, Robino, A, Rudan, I, Ruth, K S, Saleheen, D, Salomaa, V, Samani, N J, Schreiner, P J, Schulze, M B, Scott, R A, Segura-Lepe, M, Sim, X, Slater, A J, Small, K S, Smith, B H, Smith, J A, Southam, L, Spector, T D, Speliotes, E K, Stefansson, K, Steinthorsdottir, V, Stirrups, K E, Strauch, K, Stringham, H M, Stumvoll, M, Sun, L, Surendran, P, Swart, K M A, Tardif, J-C, Taylor, K D, Teumer, A, Thompson, D J, Thorleifsson, G, Thorsteinsdottir, U, Thuesen, B H, Tönjes, A, Torres, M, Tsafantakis, E, Tuomilehto, J, Uitterlinden, A G, Uusitupa, M, van Duijn, C M, Vanhala, M, Varma, R, Vermeulen, S H, Vestergaard, H, Vitart, V, Vogt, T F, Vuckovic, D, Wagenknecht, L E, Walker, M, Wallentin, L, Wang, F, Wang, C A, Wang, S, Wareham, N J, Warren, H R, Waterworth, D M, Wessel, J, White, H D, Willer, C J, Wilson, J G, Wood, A R, Wu, Y, Yaghootkar, H, Yao, J, Yerges-Armstrong, L M, Young, R, Zeggini, E, Zhan, X, Zhang, W, Hua Zhao, J, Zhao, W, Zheng, H, Zhou, W, Zillikens, M C, CHD Exome+ Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, EPIC-CVD consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, InterAct, ReproGen Consortium, T2D-Genes Consortium, The MAGIC Investigators, Rivadeneira, F, Borecki, I B, Pospisilik, J A, Deloukas, P, Frayling, T M, Lettre, G, Mohlke, K L, Rotter, J I, Kutalik, Z, Hirschhorn, J N, Cupples, L A, Loos, R J F, North, K E & Lindgren, C M 2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution ', Nature Genetics, vol. 51, no. 3, pp. 452-469 . https://doi.org/10.1038/s41588-018-0334-2
CHD Exome+ Consortium 2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution ', Nature Genetics, vol. 51, no. 3, pp. 452-469 . https://doi.org/10.1038/s41588-018-0334-2
Nature Genetics, 51(3), 452
T2D-Genes Consortium, The MAGIC Investigators, CHD Exome+ Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, EPIC-CVD Consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, InterAct & ReproGen Consortium 2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution ', Nature Genetics, vol. 51, no. 3, pp. 452-469 . https://doi.org/10.1038/s41588-018-0334-2
2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution ', Nature Genetics . https://doi.org/10.1038/s41588-018-0334-2
CHD Exome+ Consortium 2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body fat distribution ', Nature Genetics, vol. xx, no. xx, xx, pp. xx . https://doi.org/10.1038/s41588-018-0334-2
Nature Genetics, 51. Nature Publishing Group
Justice, A E, Karaderi, T, Highland, H M, Young, K L, Graff, M, Lu, Y, Turcot, V, Auer, P L, Fine, R S, Guo, X, Schurmann, C, Lempradl, A, Marouli, E, Mahajan, A, Winkler, T W, Locke, A E, Medina-Gomez, C, Esko, T, Vedantam, S, Giri, A, Lo, K S, Alfred, T, Mudgal, P, Ng, M C Y, Heard-Costa, N L, Feitosa, M F, Manning, A K, Willems, S M, Sivapalaratnam, S, Abecasis, G, Alam, D S, Allison, M, Amouyel, P, Arzumanyan, Z, Balkau, B, Bastarache, L, Bergmann, S, Bielak, L F, Blüher, M, Boehnke, M, Boeing, H, Boerwinkle, E, Böger, C A, Bork-Jensen, J, Bottinger, E P, Bowden, D W, Brandslund, I, Christensen, C, Hansen, T, Thuesen, B H & CHD Exome+ Consortium 2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution ', Nature Genetics, vol. 51, no. 3, pp. 452-469 . https://doi.org/10.1038/s41588-018-0334-2
Nature Genetics, 51, 452-469
Nature genetics, 51(3), 452-469. Nature Publishing Group
Nature Genetics
Nature genetics
Nature Genetics, 51(3), 452-469. Nature Publishing Group
Nature genetics, vol. 51, no. 3, pp. 452-469
Nat. Genet. 51, 452–469 (2019)
Justice, A E, Karaderi, T, Highland, H M, Young, K L, Graff, M, Lu, Y, Turcot, V, Auer, P L, Fine, R S, Guo, X, Schurmann, C, Lempradl, A, Marouli, E, Mahajan, A, Winkler, T W, Locke, A E, Medina-Gomez, C, Esko, T N, Vedantam, S, Giri, A, Lo, K S, Alfred, T, Mudgal, P, Ng, M C Y, Heard-Costa, N L, Feitosa, M F, Manning, A K, Willems, S M, Sivapalaratnam, S, Abecasis, G, Alam, D S, Allison, M, Amouyel, P, Arzumanyan, Z, Balkau, B, Bastarache, L, Bergmann, S, Bielak, L F, Blüher, M, Boehnke, M, Boeing, H, Boerwinkle, E, Böger, C A, Bork-Jensen, J, Bottinger, E P, Bowden, D W, Brandslund, I, Li, J, Swart, K M A, Vermeulen, S H, CHD Exome+ Consortium, Frayling, T M, Lettre, G, Mohlke, K L, Rotter, J I, Kutalik, Z, Hirschhorn, J N, Cupples, L A, Loos, R J F, North, K E & Lindgren, C M 2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution ', Nature Genetics, vol. 51, pp. 452–469 . https://doi.org/10.1038/s41588-018-0334-2
Justice, A E, Karaderi, T, Highland, H M, Young, K L, Graff, M, Lu, Y, Turcot, V, Auer, P L, Fine, R S, Guo, X, Schurmann, C, Lempradl, A, Marouli, E, Mahajan, A, Winkler, T W, Locke, A E, Medina-Gomez, C, Esko, T, Vedantam, S, Giri, A, Lo, K S, Alfred, T, Mudgal, P, Ng, M C Y, Heard-Costa, N L, Feitosa, M F, Manning, A K, Willems, S M, Sivapalaratnam, S, Abecasis, G, Alam, D S, Allison, M, Amouyel, P, Arzumanyan, Z, Balkau, B, Bastarache, L, Bergmann, S, Bielak, L F, Blüher, M, Boehnke, M, Boeing, H, Boerwinkle, E, Böger, C A, Bork-Jensen, J, Bottinger, E P, Bowden, D W, Brandslund, I, Broer, L, Burt, A A, Butterworth, A S, Caulfield, M J, Cesana, G, Chambers, J C, Chasman, D I, Chen, Y-D I, Chowdhury, R, Christensen, C, Chu, A Y, Collins, F S, Cook, J P, Cox, A J, Crosslin, D S, Danesh, J, de Bakker, P I W, de Denus, S, de Mutsert, R, Dedoussis, G, Demerath, E W, Dennis, J G, Denny, J C, Di Angelantonio, E, Dörr, M, Drenos, F, Dubé, M-P, Dunning, A M, Easton, D F, Elliott, P, Evangelou, E, Farmaki, A-E, Feng, S, Ferrannini, E, Ferrieres, J, Florez, J C, Fornage, M, Fox, C S, Franks, P W, Friedrich, N, Gan, W, Gandin, I, Gasparini, P, Giedraitis, V, Girotto, G, Gorski, M, Grallert, H, Grarup, N, Grove, M L, Gustafsson, S, Haessler, J, Hansen, T, Hattersley, A T, Hayward, C, Heid, I M, Holmen, O L, Kees Hovingh, G, Howson, J M M, Hu, Y, Hung, Y-J, Hveem, K, Ikram, M A, Ingelsson, E, Jackson, A U, Jarvik, G P, Jia, Y, Jørgensen, T, Jousilahti, P, Justesen, J M, Kahali, B, Karaleftheri, M, Kardia, S L R, Karpe, F, Kee, F, Kitajima, H, Komulainen, P, Kooner, J S, Kovacs, P, Krämer, B K, Kuulasmaa, K, Kuusisto, J, Laakso, M, Lakka, T A, Lamparter, D, Lange, L A, Langenberg, C, Larson, E B, Lee, N R, Lee, W-J, Lehtimäki, T, Lewis, C E, Li, H, Li, J, Li-Gao, R, Lin, L-A, Lin, X, Lind, L, Lindström, J, Linneberg, A, Liu, C-T, Liu, D J, Luan, J, Lyytikäinen, L-P, MacGregor, S, Mägi, R, Männistö, S, Marenne, G, Marten, J, Masca, N G D, McCarthy, M I, Meidtner, K, Mihailov, E, Moilanen, L, Moitry, M, Mook-Kanamori, D O, Morgan, A, Morris, A P, Müller-Nurasyid, M, Munroe, P B, Narisu, N, Nelson, C P, Neville, M, Ntalla, I, Owen, K R, O'Connell, J R, Pedersen, O, Peloso, G M, Pennell, C E, Perola, M, Perry, J A, Perry, J R B, Pers, T H, Ewing, A, Polasek, O, Raitakari, O T, Rasheed, A, Raulerson, C K, Rauramaa, R, Reilly, D F, Reiner, A P, Ridker, P M, Rivas, M A, Robertson, N R, Robino, A, Rudan, I, Ruth, K S, Saleheen, D, Salomaa, V, Samani, N J, Schreiner, P J, Schulze, M B, Scott, R A, Segura-Lepe, M, Sim, X, Slater, A J, Small, K S, Smith, B H, Smith, J A, Southam, L, Spector, T D, Speliotes, E K, Stefansson, K, Steinthorsdottir, V, Stirrups, K E, Strauch, K, Stringham, H M, Stumvoll, M, Sun, L, Surendran, P, Swart, K M A, Tardif, J-C, Taylor, K D, Teumer, A, Thompson, D J, Thorleifsson, G, Thorsteinsdottir, U, Thuesen, B H, Tönjes, A, Torres, M, Tsafantakis, E, Tuomilehto, J, Uitterlinden, A G, Uusitupa, M, van Duijn, C M, Vanhala, M, Varma, R, Vermeulen, S H, Vestergaard, H, Vitart, V, Vogt, T F, Vuckovic, D, Wagenknecht, L E, Walker, M, Wallentin, L, Wang, F, Wang, C A, Wang, S, Wareham, N J, Warren, H R, Waterworth, D M, Wessel, J, White, H D, Willer, C J, Wilson, J G, Wood, A R, Wu, Y, Yaghootkar, H, Yao, J, Yerges-Armstrong, L M, Young, R, Zeggini, E, Zhan, X, Zhang, W, Hua Zhao, J, Zhao, W, Zheng, H, Zhou, W, Zillikens, M C, CHD Exome+ Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, EPIC-CVD consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, InterAct, ReproGen Consortium, T2D-Genes Consortium, The MAGIC Investigators, Rivadeneira, F, Borecki, I B, Pospisilik, J A, Deloukas, P, Frayling, T M, Lettre, G, Mohlke, K L, Rotter, J I, Kutalik, Z, Hirschhorn, J N, Cupples, L A, Loos, R J F, North, K E & Lindgren, C M 2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution ', Nature Genetics, vol. 51, no. 3, pp. 452-469 . https://doi.org/10.1038/s41588-018-0334-2
CHD Exome+ Consortium 2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution ', Nature Genetics, vol. 51, no. 3, pp. 452-469 . https://doi.org/10.1038/s41588-018-0334-2
Nature Genetics, 51(3), 452
T2D-Genes Consortium, The MAGIC Investigators, CHD Exome+ Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, EPIC-CVD Consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, InterAct & ReproGen Consortium 2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution ', Nature Genetics, vol. 51, no. 3, pp. 452-469 . https://doi.org/10.1038/s41588-018-0334-2
2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution ', Nature Genetics . https://doi.org/10.1038/s41588-018-0334-2
CHD Exome+ Consortium 2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body fat distribution ', Nature Genetics, vol. xx, no. xx, xx, pp. xx . https://doi.org/10.1038/s41588-018-0334-2
Nature Genetics, 51. Nature Publishing Group
Justice, A E, Karaderi, T, Highland, H M, Young, K L, Graff, M, Lu, Y, Turcot, V, Auer, P L, Fine, R S, Guo, X, Schurmann, C, Lempradl, A, Marouli, E, Mahajan, A, Winkler, T W, Locke, A E, Medina-Gomez, C, Esko, T, Vedantam, S, Giri, A, Lo, K S, Alfred, T, Mudgal, P, Ng, M C Y, Heard-Costa, N L, Feitosa, M F, Manning, A K, Willems, S M, Sivapalaratnam, S, Abecasis, G, Alam, D S, Allison, M, Amouyel, P, Arzumanyan, Z, Balkau, B, Bastarache, L, Bergmann, S, Bielak, L F, Blüher, M, Boehnke, M, Boeing, H, Boerwinkle, E, Böger, C A, Bork-Jensen, J, Bottinger, E P, Bowden, D W, Brandslund, I, Christensen, C, Hansen, T, Thuesen, B H & CHD Exome+ Consortium 2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution ', Nature Genetics, vol. 51, no. 3, pp. 452-469 . https://doi.org/10.1038/s41588-018-0334-2
Body fat distribution is a risk factor for adverse cardiovascular health consequences. We analyzed the association of body fat distribution, assessed by waist-to-hip ratio adjusted for body mass index, with 228,985 predicted coding and splice site va
Autor:
Justice, Anne E, Karaderi, Tugce, Highland, Heather M, Young, Kristin L, Graff, Mariaelisa, Lu, Yingchang, Turcot, Valérie, Auer, Paul L, Fine, Rebecca S, Guo, Xiuqing, Schurmann, Claudia, Lempradl, Adelheid, Marouli, Eirini, Mahajan, Anubha, Winkler, Thomas W, Locke, Adam E, Medina-Gomez, Carolina, Esko, Tõnu, Vedantam, Sailaja, Giri, Ayush, Lo, Ken Sin, Alfred, Tamuno, Mudgal, Poorva, Ng, Maggie CY, Heard-Costa, Nancy L, Feitosa, Mary F, Manning, Alisa K, Willems, Sara M, Sivapalaratnam, Suthesh, Abecasis, Goncalo, Alam, Dewan S, Allison, Matthew, Amouyel, Philippe, Arzumanyan, Zorayr, Balkau, Beverley, Bastarache, Lisa, Bergmann, Sven, Bielak, Lawrence F, Blüher, Matthias, Boehnke, Michael, Boeing, Heiner, Boerwinkle, Eric, Böger, Carsten A, Bork-Jensen, Jette, Bottinger, Erwin P, Bowden, Donald W, Brandslund, Ivan, Broer, Linda, Burt, Amber A, Butterworth, Adam S, Caulfield, Mark J, Cesana, Giancarlo, Chambers, John C, Chasman, Daniel I, Chen, Yii-Der Ida, Chowdhury, Rajiv, Christensen, Cramer, Chu, Audrey Y, Collins, Francis S, Cook, James P, Cox, Amanda J, Crosslin, David S, Danesh, John, De Bakker, Paul IW, Denus, Simon De, Mutsert, Renée De, Dedoussis, George, Demerath, Ellen W, Dennis, Joe G, Denny, Josh C, Di Angelantonio, Emanuele, Dörr, Marcus, Drenos, Fotios, Dubé, Marie-Pierre, Dunning, Alison M, Easton, Douglas F, Elliott, Paul, Evangelou, Evangelos, Farmaki, Aliki-Eleni, Feng, Shuang, Ferrannini, Ele, Ferrieres, Jean, Florez, Jose C, Fornage, Myriam, Fox, Caroline S, Franks, Paul W, Friedrich, Nele, Gan, Wei, Gandin, Ilaria, Gasparini, Paolo, Giedraitis, Vilmantas, Girotto, Giorgia, Gorski, Mathias, Grallert, Harald, Grarup, Niels, Grove, Megan L, Gustafsson, Stefan, Haessler, Jeff, Hansen, Torben, Hattersley, Andrew T, Hayward, Caroline, Heid, Iris M, Holmen, Oddgeir L, Hovingh, G Kees, Howson, Joanna MM, Hu, Yao, Hung, Yi-Jen, Hveem, Kristian, Ikram, M Arfan, Ingelsson, Erik, Jackson, Anne U, Jarvik, Gail P, Jia, Yucheng, Jørgensen, Torben, Jousilahti, Pekka, Justesen, Johanne M, Kahali, Bratati, Karaleftheri, Maria, Kardia, Sharon LR, Karpe, Fredrik, Kee, Frank, Kitajima, Hidetoshi, Komulainen, Pirjo, Kooner, Jaspal S, Kovacs, Peter, Krämer, Bernhard K, Kuulasmaa, Kari, Kuusisto, Johanna, Laakso, Markku, Lakka, Timo A, Lamparter, David, Lange, Leslie A, Langenberg, Claudia, Larson, Eric B, Lee, Nanette R, Lee, Wen-Jane, Lehtimäki, Terho, Lewis, Cora E, Li, Huaixing, Li, Jin, Li-Gao, Ruifang, Lin, Li-An, Lin, Xu, Lind, Lars, Lindström, Jaana, Linneberg, Allan, Liu, Ching-Ti, Liu, Dajiang J, Luan, Jian'an, Lyytikäinen, Leo-Pekka, MacGregor, Stuart, Mägi, Reedik, Männistö, Satu, Marenne, Gaëlle, Marten, Jonathan, Masca, Nicholas GD, McCarthy, Mark I, Meidtner, Karina, Mihailov, Evelin, Moilanen, Leena, Moitry, Marie, Mook-Kanamori, Dennis O, Morgan, Anna, Morris, Andrew P, Müller-Nurasyid, Martina, Munroe, Patricia B, Narisu, Narisu, Nelson, Christopher P, Neville, Matt, Ntalla, Ioanna, O'Connell, Jeffrey R, Owen, Katharine R, Pedersen, Oluf, Peloso, Gina M, Pennell, Craig E, Perola, Markus, Perry, James A, Perry, John RB, Pers, Tune H, Ewing, Ailith, Polasek, Ozren, Raitakari, Olli T, Rasheed, Asif, Raulerson, Chelsea K, Rauramaa, Rainer, Reilly, Dermot F, Reiner, Alex P, Ridker, Paul M, Rivas, Manuel A, Robertson, Neil R, Robino, Antonietta, Rudan, Igor, Ruth, Katherine S, Saleheen, Danish, Salomaa, Veikko, Samani, Nilesh J, Schreiner, Pamela J, Schulze, Matthias B, Scott, Robert A, Segura-Lepe, Marcelo, Sim, Xueling, Slater, Andrew J, Small, Kerrin S, Smith, Blair H, Smith, Jennifer A, Southam, Lorraine, Spector, Timothy D, Speliotes, Elizabeth K, Stefansson, Kari, Steinthorsdottir, Valgerdur, Stirrups, Kathleen E, Strauch, Konstantin, Stringham, Heather M, Stumvoll, Michael, Sun, Liang, Surendran, Praveen, Swart, Karin MA, Tardif, Jean-Claude, Taylor, Kent D, Teumer, Alexander, Thompson, Deborah J, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Thuesen, Betina H, Tönjes, Anke, Torres, Mina, Tsafantakis, Emmanouil, Tuomilehto, Jaakko, Uitterlinden, André G, Uusitupa, Matti, Van Duijn, Cornelia M, Vanhala, Mauno, Varma, Rohit, Vermeulen, Sita H, Vestergaard, Henrik, Vitart, Veronique, Vogt, Thomas F, Vuckovic, Dragana, Wagenknecht, Lynne E, Walker, Mark, Wallentin, Lars, Wang, Feijie, Wang, Carol A, Wang, Shuai, Wareham, Nicholas J, Warren, Helen R, Waterworth, Dawn M, Wessel, Jennifer, White, Harvey D, Willer, Cristen J, Wilson, James G, Wood, Andrew R, Wu, Ying, Yaghootkar, Hanieh, Yao, Jie, Yerges-Armstrong, Laura M, Young, Robin, Zeggini, Eleftheria, Zhan, Xiaowei, Zhang, Weihua, Zhao, Jing Hua, Zhao, Wei, Zheng, He, Zhou, Wei, Zillikens, M Carola, Rivadeneira, Fernando, Borecki, Ingrid B, Pospisilik, J Andrew, Deloukas, Panos, Frayling, Timothy M, Lettre, Guillaume, Mohlke, Karen L, Rotter, Jerome I, Kutalik, Zoltán, Hirschhorn, Joel N, Cupples, L Adrienne, Loos, Ruth JF, North, Kari E, Lindgren, Cecilia M, CHD Exome+ Consortium, Cohorts For Heart And Aging Research In Genomic Epidemiology (CHARGE) Consortium, EPIC-CVD Consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, InterAct, ReproGen Consortium, T2D-Genes Consortium, MAGIC Investigators
Body-fat distribution is a risk factor for adverse cardiovascular health consequences. We analyzed the association of body-fat distribution, assessed by waist-to-hip ratio adjusted for body mass index, with 228,985 predicted coding and splice site va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d155e55cab6201548d4294b6f7a099b
Autor:
Turcot, Valérie, Lu, Yingchang, Highland, Heather M, Schurmann, Claudia, Justice, Anne E, Fine, Rebecca S, Bradfield, Jonathan P, Esko, Tõnu, Giri, Ayush, Graff, Mariaelisa, Guo, Xiuqing, Hendricks, Audrey E, Karaderi, Tugce, Lempradl, Adelheid, Locke, Adam E, Mahajan, Anubha, Marouli, Eirini, Sivapalaratnam, Suthesh, Young, Kristin L, Alfred, Tamuno, Feitosa, Mary F, Masca, Nicholas GD, Manning, Alisa K, Medina-Gomez, Carolina, Mudgal, Poorva, Ng, Maggie CY, Reiner, Alex P, Vedantam, Sailaja, Willems, Sara M, Winkler, Thomas W, Abecasis, Gonçalo, Aben, Katja K, Alam, Dewan S, Alharthi, Sameer E, Allison, Matthew, Amouyel, Philippe, Asselbergs, Folkert W, Auer, Paul L, Balkau, Beverley, Bang, Lia E, Barroso, Inês, Bastarache, Lisa, Benn, Marianne, Bergmann, Sven, Bielak, Lawrence F, Blüher, Matthias, Boehnke, Michael, Boeing, Heiner, Boerwinkle, Eric, Böger, Carsten A, Bork-Jensen, Jette, Bots, Michiel L, Bottinger, Erwin P, Bowden, Donald W, Brandslund, Ivan, Breen, Gerome, Brilliant, Murray H, Broer, Linda, Brumat, Marco, Burt, Amber A, Butterworth, Adam S, Campbell, Peter T, Cappellani, Stefania, Carey, David J, Catamo, Eulalia, Caulfield, Mark J, Chambers, John C, Chasman, Daniel I, Chen, Yii-Der I, Chowdhury, Rajiv, Christensen, Cramer, Chu, Audrey Y, Cocca, Massimiliano, Collins, Francis S, Cook, James P, Corley, Janie, Corominas Galbany, Jordi, Cox, Amanda J, Crosslin, David S, Cuellar-Partida, Gabriel, D'Eustacchio, Angela, Danesh, John, Davies, Gail, Bakker, Paul IW, Groot, Mark CH, Mutsert, Renée, Deary, Ian J, Dedoussis, George, Demerath, Ellen W, Heijer, Martin, Hollander, Anneke I, Ruijter, Hester M, Dennis, Joe G, Denny, Josh C, Di Angelantonio, Emanuele, Drenos, Fotios, Du, Mengmeng, Dubé, Marie-Pierre, Dunning, Alison M, Easton, Douglas F, Edwards, Todd L, Ellinghaus, David, Ellinor, Patrick T, Elliott, Paul, Evangelou, Evangelos, Farmaki, Aliki-Eleni, Farooqi, I Sadaf, Faul, Jessica D, Fauser, Sascha, Feng, Shuang, Ferrannini, Ele, Ferrieres, Jean, Florez, Jose C, Ford, Ian, Fornage, Myriam, Franco, Oscar H, Franke, Andre, Franks, Paul W, Friedrich, Nele, Frikke-Schmidt, Ruth, Galesloot, Tessel E, Gan, Wei, Gandin, Ilaria, Gasparini, Paolo, Gibson, Jane, Giedraitis, Vilmantas, Gjesing, Anette P, Gordon-Larsen, Penny, Gorski, Mathias, Grabe, Hans-Jörgen, Grant, Struan FA, Grarup, Niels, Griffiths, Helen L, Grove, Megan L, Gudnason, Vilmundur, Gustafsson, Stefan, Haessler, Jeff, Hakonarson, Hakon, Hammerschlag, Anke R, Hansen, Torben, Harris, Kathleen Mullan, Harris, Tamara B, Hattersley, Andrew T, Have, Christian T, Hayward, Caroline, He, Liang, Heard-Costa, Nancy L, Heath, Andrew C, Heid, Iris M, Helgeland, Øyvind, Hernesniemi, Jussi, Hewitt, Alex W, Holmen, Oddgeir L, Hovingh, G Kees, Howson, Joanna MM, Hu, Yao, Huang, Paul L, Huffman, Jennifer E, Ikram, M Arfan, Ingelsson, Erik, Jackson, Anne U, Jansson, Jan-Håkan, Jarvik, Gail P, Jensen, Gorm B, Jia, Yucheng, Johansson, Stefan, Jørgensen, Marit E, Jørgensen, Torben, Jukema, J Wouter, Kahali, Bratati, Kahn, René S, Kähönen, Mika, Kamstrup, Pia R, Kanoni, Stavroula, Kaprio, Jaakko, Karaleftheri, Maria, Kardia, Sharon LR, Karpe, Fredrik, Kathiresan, Sekar, Kee, Frank, Kiemeney, Lambertus A, Kim, Eric, Kitajima, Hidetoshi, Komulainen, Pirjo, Kooner, Jaspal S, Kooperberg, Charles, Korhonen, Tellervo, Kovacs, Peter, Kuivaniemi, Helena, Kutalik, Zoltán, Kuulasmaa, Kari, Kuusisto, Johanna, Laakso, Markku, Lakka, Timo A, Lamparter, David, Lange, Ethan M, Lange, Leslie A, Langenberg, Claudia, Larson, Eric B, Lee, Nanette R, Lehtimäki, Terho, Lewis, Cora E, Li, Huaixing, Li, Jin, Li-Gao, Ruifang, Lin, Honghuang, Lin, Keng-Hung, Lin, Li-An, Lin, Xu, Lind, Lars, Lindström, Jaana, Linneberg, Allan, Liu, Ching-Ti, Liu, Dajiang J, Liu, Yongmei, Lo, Ken S, Lophatananon, Artitaya, Lotery, Andrew J, Loukola, Anu, Luan, Jian'an, Lubitz, Steven A, Lyytikäinen, Leo-Pekka, Männistö, Satu, Marenne, Gaëlle, Mazul, Angela L, McCarthy, Mark I, McKean-Cowdin, Roberta, Medland, Sarah E, Meidtner, Karina, Milani, Lili, Mistry, Vanisha, Mitchell, Paul, Mohlke, Karen L, Moilanen, Leena, Moitry, Marie, Montgomery, Grant W, Mook-Kanamori, Dennis O, Moore, Carmel, Mori, Trevor A, Morris, Andrew D, Morris, Andrew P, Müller-Nurasyid, Martina, Munroe, Patricia B, Nalls, Mike A, Narisu, Narisu, Nelson, Christopher P, Neville, Matt, Nielsen, Sune F, Nikus, Kjell, Njølstad, Pål R, Nordestgaard, Børge G, Nyholt, Dale R, O'Connel, Jeffrey R, O'Donoghue, Michelle L, Olde Loohuis, Loes M, Ophoff, Roel A, Owen, Katharine R, Packard, Chris J, Padmanabhan, Sandosh, Palmer, Colin NA, Palmer, Nicholette D, Pasterkamp, Gerard, Patel, Aniruddh P, Pattie, Alison, Pedersen, Oluf, Peissig, Peggy L, Peloso, Gina M, Pennell, Craig E, Perola, Markus, Perry, James A, Perry, John RB, Pers, Tune H, Person, Thomas N, Peters, Annette, Petersen, Eva RB, Peyser, Patricia A, Pirie, Ailith, Polasek, Ozren, Polderman, Tinca J, Puolijoki, Hannu, Raitakari, Olli T, Rasheed, Asif, Rauramaa, Rainer, Reilly, Dermot F, Renström, Frida, Rheinberger, Myriam, Ridker, Paul M, Rioux, John D, Rivas, Manuel A, Roberts, David J, Robertson, Neil R, Robino, Antonietta, Rolandsson, Olov, Rudan, Igor, Ruth, Katherine S, Saleheen, Danish, Salomaa, Veikko, Samani, Nilesh J, Sapkota, Yadav, Sattar, Naveed, Schoen, Robert E, Schreiner, Pamela J, Schulze, Matthias B, Scott, Robert A, Segura-Lepe, Marcelo P, Shah, Svati H, Sheu, Wayne H-H, Sim, Xueling, Slater, Andrew J, Small, Kerrin S, Smith, Albert V, Southam, Lorraine, Spector, Timothy D, Speliotes, Elizabeth K, Starr, John M, Stefansson, Kari, Steinthorsdottir, Valgerdur, Stirrups, Kathleen E, Strauch, Konstantin, Stringham, Heather M, Stumvoll, Michael, Sun, Liang, Surendran, Praveen, Swift, Amy J, Tada, Hayato, Tansey, Katherine E, Tardif, Jean-Claude, Taylor, Kent D, Teumer, Alexander, Thompson, Deborah J, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Thuesen, Betina H, Tönjes, Anke, Tromp, Gerard, Trompet, Stella, Tsafantakis, Emmanouil, Tuomilehto, Jaakko, Tybjaerg-Hansen, Anne, Tyrer, Jonathan P, Uher, Rudolf, Uitterlinden, André G, Uusitupa, Matti, Laan, Sander W, Duijn, Cornelia M, Leeuwen, Nienke, Van Setten, Jessica, Vanhala, Mauno, Varbo, Anette, Varga, Tibor V, Varma, Rohit, Velez Edwards, Digna R, Vermeulen, Sita H, Veronesi, Giovanni, Vestergaard, Henrik, Vitart, Veronique, Vogt, Thomas F, Völker, Uwe, Vuckovic, Dragana, Wagenknecht, Lynne E, Walker, Mark, Wallentin, Lars, Wang, Feijie, Wang, Carol A, Wang, Shuai, Wang, Yiqin, Ware, Erin B, Wareham, Nicholas J, Warren, Helen R, Waterworth, Dawn M, Wessel, Jennifer, White, Harvey D, Willer, Cristen J, Wilson, James G, Witte, Daniel R, Wood, Andrew R, Wu, Ying, Yaghootkar, Hanieh, Yao, Jie, Yao, Pang, Yerges-Armstrong, Laura M, Young, Robin, Zeggini, Eleftheria, Zhan, Xiaowei, Zhang, Weihua, Zhao, Jing Hua, Zhao, Wei, Zhou, Wei, Zondervan, Krina T, CHD Exome+ Consortium, EPIC-CVD Consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, EPIC InterAct Consortium, INTERVAL Study, ReproGen Consortium, T2D-Genes Consortium, MAGIC Investigators, Understanding Society Scientific Group, Rotter, Jerome I, Pospisilik, John A, Rivadeneira, Fernando, Borecki, Ingrid B, Deloukas, Panos, Frayling, Timothy M, Lettre, Guillaume, North, Kari E, Lindgren, Cecilia M, Hirschhorn, Joel N, Loos, Ruth JF
Genome-wide association studies (GWAS) have identified >250 loci for body mass index (BMI), implicating pathways related to neuronal biology. Most GWAS loci represent clusters of common, noncoding variants from which pinpointing causal genes remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6a694f3fafc4ca7b08cb26857d2a72e
Autor:
Alison Pattie, Ailith Pirie, Francis S. Collins, Charles Kooperberg, Nienke van Leeuwen, Carmel Moore, Sharon L.R. Kardia, Neil R. Robertson, Lisa Bastarache, Allan Linneberg, Peter T. Campbell, Helena Kuivaniemi, Struan F.A. Grant, Sascha Fauser, Sekar Kathiresan, Lars Lind, Erin B. Ware, Olli T. Raitakari, Dawn M. Waterworth, James G. Wilson, Markus Perola, Chris J. Packard, Michelle L. O'Donoghue, Fredrik Karpe, Roel A. Ophoff, Sailaja Vedantam, Artitaya Lophatananon, Uwe Völker, Emmanouil Tsafantakis, Hakon Hakonarson, Dajiang J. Liu, Craig E. Pennell, Xueling Sim, Jennifer E. Huffman, Sandosh Padmanabhan, Digna R. Velez Edwards, Michiel L. Bots, Ayush Giri, Renée de Mutsert, Emanuele Di Angelantonio, Nicholas J. Wareham, Jin Li, Gail P. Jarvik, Evangelos Evangelou, Anne Tybjærg-Hansen, Patricia B. Munroe, Penny Gordon-Larsen, Lia E. Bang, Ivan Brandslund, Hester M. den Ruijter, Jussi Hernesniemi, Nancy L. Heard-Costa, Angela L. Mazul, Jonathan Tyrer, Danish Saleheen, Mark J. Caulfield, John Andrew Pospisilik, Annette Peters, Caroline Hayward, Iris M. Heid, J. Wouter Jukema, Valérie Turcot, Matt Neville, Rudolf Uher, Patricia A. Peyser, Jessica D. Faul, Asif Rasheed, Shuai Wang, John C. Chambers, Jordi Corominas Galbany, Murray H. Brilliant, Yucheng Jia, Torben Hansen, Veikko Salomaa, Mary F. Feitosa, Mathias Gorski, Li-An Lin, George Dedoussis, Honghuang Lin, Ethan M. Lange, Veronique Vitart, Bratati Kahali, Alexander Teumer, Jerome I. Rotter, Wayne H-H Sheu, Vilmantas Giedraitis, Aliki-Eleni Farmaki, Lorraine Southam, Ele Ferrannini, Anette P. Gjesing, Krina T. Zondervan, Stavroula Kanoni, David J. Roberts, Rebecca S. Fine, Svati H. Shah, Tugce Karaderi, Claudia Langenberg, Stefan Johansson, Elizabeth K. Speliotes, Alexander P. Reiner, Ching-Ti Liu, Yiqin Wang, Pål R. Njølstad, Gabriel Cuellar-Partida, Amanda J. Cox, Tim D. Spector, Paul W. Franks, Anke Tönjes, John D. Rioux, Jeffrey Haessler, Paul L. Auer, Ingrid B. Borecki, Deborah J. Thompson, Weihua Zhang, John R. B. Perry, Paul Elliott, Folkert W. Asselbergs, Myriam Fornage, Ken Sin Lo, Marie Moitry, Paul Mitchell, Martin den Heijer, Zoltán Kutalik, Tune H. Pers, Kari Stefansson, Kari Kuulasmaa, Robert E. Schoen, Mark C.H. De Groot, Laura M. Yerges-Armstrong, Jing Hua Zhao, Beverley Balkau, Peggy L. Peissig, Michael Boehnke, Janie Corley, Katharine R. Owen, Unnur Thorsteinsdottir, Naveed Sattar, Sita H. Vermeulen, Thomas N. Person, Mark I. McCarthy, Paul I.W. de Bakker, David Lamparter, Poorva Mudgal, Nicholette D. Palmer, Maria Karaleftheri, Jan-Håkan Jansson, Ozren Polasek, Ruth J. F. Loos, Daniel R. Witte, Dermot F. Reilly, Anubha Mahajan, Stella Trompet, James A. Perry, Yingchang Lu, Claudia Schurmann, Yii-Der Ida Chen, Hidetoshi Kitajima, Dale R. Nyholt, John Danesh, Pamela J. Schreiner, Narisu Narisu, Jose C. Florez, Adelheid Lempradl, Gerome Breen, Torben Jørgensen, Anu Loukola, Joe Dennis, Hans-Jörgen Grabe, Vilmundur Gudnason, Timo A. Lakka, Heather M. Highland, Sven Bergmann, Marie-Pierre Dubé, Giovanni Veronesi, Martina Müller-Nurasyid, Jaakko Tuomilehto, Nele Friedrich, Joel N. Hirschhorn, Pia R. Kamstrup, Nilesh J. Samani, Josh C. Denny, Mika Kähönen, Massimiliano Cocca, Liang Sun, Karina Meidtner, Carsten A. Böger, Sara M. Willems, Marcelo P. Segura-Lepe, Johanna Kuusisto, Hanieh Yaghootkar, Konstantin Strauch, Ruth Frikke-Schmidt, Jane Gibson, Matti Uusitupa, Oscar H. Franco, Yongmei Liu, Heather M. Stringham, Rohit Varma, Grant W. Montgomery, Dennis O. Mook-Kanamori, Stefania Cappellani, Paul L. Huang, Albert V. Smith, Eric Kim, Anke R. Hammerschlag, Katherine S. Ruth, Carolina Medina-Gomez, Gerard Pasterkamp, Cristen J. Willer, Alisa K. Manning, Frida Renström, René S. Kahn, Lili Milani, Feijie Wang, Tessel E. Galesloot, Fernando Rivadeneira, Leo-Pekka Lyytikäinen, Adam S. Butterworth, Tamara B. Harris, Matthew A. Allison, Paul M. Ridker, David J. Carey, Todd L. Edwards, Panos Deloukas, Xiuqing Guo, Lawrence F. Bielak, Leena Moilanen, Heiner Boeing, Peter Kovacs, Karen L. Mohlke, Myriam Rheinberger, Cramer Christensen, Betina H. Thuesen, Mike A. Nalls, Erik Ingelsson, Nicholas G. D. Masca, Colin N. A. Palmer, Audrey E. Hendricks, Linda Broer, Vanisha Mistry, Praveen Surendran, Audrey Y. Chu, Rainer Rauramaa, Angela D'Eustacchio, Helen Griffiths, Satu Männistö, Patrick T. Ellinor, Terho Lehtimäki, Katherine E. Tansey, I. Sadaf Farooqi, Gaëlle Marenne, Anneke I. den Hollander, Jessica van Setten, Hannu Puolijoki, Tinca J. C. Polderman, Timothy M. Frayling, Niels Grarup, Eric Boerwinkle, Gonçalo R. Abecasis, Adam E. Locke, Mengmeng Du, Manuel A. Rivas, Philippe Amouyel, Jaakko Kaprio, Leslie A. Lange, Loes M. Olde Loohuis, Trevor A. Mori, Lambertus A. Kiemeney, Wei Zhao, Eva Rb Petersen, Huaixing Li, Thomas W. Winkler, Tellervo Korhonen, Kathleen Stirrups, Jean Ferrières, Wei Zhou, Ian J. Deary, Guillaume Lettre, M. Arfan Ikram, Alex W. Hewitt, Marit E. Jørgensen, Ian Ford, Liang He, Mark Walker, Stefan Gustafsson, Andre Franke, Yao Hu, Jaana Lindström, Jonathan P. Bradfield, Anne E. Justice, Kristin L. Young, Sander W. van der Laan, Shuang Feng, Yadav Sapkota, Douglas F. Easton, Cornelia M. van Duijn, Amy J. Swift, Kjell Nikus, Helen R. Warren, Christian Theil Have, Wei Gan, Steven A. Lubitz, Harvey D. White, Pirjo Komulainen, John M. Starr, Jeffrey R. O'Connel, Anette Varbo, Daniel I. Chasman, Ruifang Li-Gao, Lynne E. Wagenknecht, Matthias Blüher, Xiaowei Zhan, Thomas F. Vogt, Eleftheria Zeggini, Tamuno Alfred, Katja K.H. Aben, Lars Wallentin, Joanna M. M. Howson, Jie Yao, Eulalia Catamo, Henrik Vestergaard, Gina M. Peloso, Markku Laakso, Matthias B. Schulze, Hayato Tada, Jennifer Wessel, Andrew R. Wood, Erwin P. Bottinger, Cora E. Lewis, Robin Young, Carol A. Wang, Oddgeir L. Holmen, Andrew J. Slater, Jean-Claude Tardif, Xu Lin, Inês Barroso, Gail Davies, Tibor V. Varga, Andrew J. Lotery, Igor Rudan, Andrew T. Hattersley, Michael Stumvoll, David Ellinghaus, Andrew C. Heath, Frank Kee, Christopher P. Nelson, Donald W. Bowden, Alison M. Dunning, Marianne Benn, Oluf Pedersen, Amber A. Burt, Aniruddh P. Patel, G. Kees Hovingh, David S. Crosslin, Gorm B. Jensen, Keng-Hung Lin, Dewan S. Alam, Jian'an Luan, Ying Wu, Tõnu Esko, Kathleen Mullan Harris, Antonietta Robino, Anne U. Jackson, Eirini Marouli, Robert A. Scott, Jette Bork-Jensen, Olov Rolandsson, Nanette R. Lee, Gerard Tromp, Megan L. Grove, Suthesh Sivapalaratnam, Sameer E. Al-Harthi, Roberta McKean-Cowdin, Paolo Gasparini, Ellen W. Demerath, Marco Brumat, Maggie C.Y. Ng, Børge G. Nordestgaard, Kari E. North, Rajiv Chowdhury, Mauno Vanhala, Andrew P. Morris, Sarah E. Medland, Sune F. Nielsen, Ilaria Gandin, Øyvind Helgeland, James P. Cook, Kent D. Taylor, Andrew D. Morris, Gudmar Thorleifsson, André G. Uitterlinden, Pang Yao, Valgerdur Steinthorsdottir, Eric B. Larson, Kerrin S. Small, Cecilia M. Lindgren, Dragana Vuckovic, Mariaelisa Graff, Fotios Drenos, Jaspal S. Kooner
Publikováno v:
Turcot, V, Lu, Y, Highland, H M, Schurmann, C, Justice, A E, Fine, R S, Bradfield, J P, Esko, T, Giri, A, Graff, M, Guo, X, Hendricks, A E, Karaderi, T, Lempradl, A, Locke, A E, Mahajan, A, Marouli, E, Sivapalaratnam, S, Young, K L, Alfred, T, Feitosa, M F, Masca, N G D, Manning, A K, Medina-Gomez, C, Mudgal, P, Ng, M C Y, Reiner, A P, Vedantam, S, Willems, S M, Winkler, T W, Abecasis, G, Aben, K K, Alam, D S, Alharthi, S E, Allison, M, Amouyel, P, Asselbergs, F W, Auer, P L & Balkau, B & Bang, L E & Corley, J & Davies, G & Deary, I J & Hayward, C & Morris, A D & Pattie, A & Polasek, O & Rudan, I & Starr, J M & Vitart, V 2017, ' Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity ', Nature Genetics, vol. 50, no. 1, pp. 26-41 . https://doi.org/10.1038/s41588-017-0011-x
Turcot, V, Lu, Y, Highland, H M, Schurmann, C, Justice, A E, Fine, R S, Bradfield, J P, Esko, T, Giri, A, Graff, M, Guo, X, Hendricks, A E, Karaderi, T, Lempradl, A, Locke, A E, Mahajan, A, Marouli, E, Sivapalaratnam, S, Young, K L, Alfred, T, Feitosa, M F, Masca, N G D, Manning, A K, Medina-Gomez, C, Mudgal, P, Ng, M C Y, Reiner, A P, Vedantam, S, Willems, S M, Winkler, T W, Abecasis, G, Aben, K K, Alam, D S, Alharthi, S E, Allison, M, Amouyel, P, Asselbergs, F W, Auer, P L, Balkau, B, Bang, L E, Barroso, I, Bastarache, L, Benn, M, Bergmann, S, Bielak, L F, Blüher, M, Boehnke, M, Boeing, H, Boerwinkle, E, Lophatananon, A, Morris, A & CHD Exome+ Consortium 2018, ' Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity ', Nature Genetics, vol. 50, no. 1, pp. 26-35 . https://doi.org/10.1038/s41588-017-0011-x
Turcot, V, Lu, Y, Highland, H M, Schurmann, C, Justice, A E, Fine, R S, Bradfield, J P, Esko, T, Giri, A, Graff, M, Guo, X, Hendricks, A E, Karaderi, T, Lempradl, A, Locke, A E, Mahajan, A, Marouli, E, Sivapalaratnam, S, Young, K L, Alfred, T, Feitosa, M F, Masca, N G D, Manning, A K, Medina-Gomez, C, Mudgal, P, Ng, M C Y, Reiner, A P, Vedantam, S, Willems, S M, Winkler, T W, Abecasis, G, Aben, K K, Alam, D S, Alharthi, S E, Allison, M, Amouyel, P, Asselbergs, F W, Auer, P L, Balkau, B, Bang, L E, Barroso, I, Bastarache, L, Benn, M, Bergmann, S, Bielak, L F, Blüher, M, Boehnke, M, Boeing, H, Hammerschlag, A R & Polderman, T J 2018, ' Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity ', Nature Genetics, vol. 50, no. 1, pp. 26-41 . https://doi.org/10.1038/s41588-017-0011-x
Turcot, V, Lu, Y, Highland, H M, Schurmann, C, Justice, A E, Fine, R S, Bradfield, J P, Esko, T, Giri, A, Graff, M, Guo, X, Hendricks, A E, Karaderi, T, Lempradl, A, Locke, A E, Mahajan, A, Marouli, E, Sivapalaratnam, S, Young, K L, Alfred, T, Feitosa, M F, Masca, N G D, Manning, A K, Medina-Gomez, C, Mudgal, P, Ng, M C Y, Reiner, A P, Vedantam, S, Willems, S M, Winkler, T W, Abecasis, G, Aben, K K, Alam, D S, Alharthi, S E, Allison, M, Amouyel, P, Asselbergs, F W, Auer, P L, Balkau, B, Bang, L E, Barroso, I, Bastarache, L, Benn, M, Bergmann, S, Bielak, L F, Blüher, M, Boehnke, M, Boeing, H, Boerwinkle, E, Jørgensen, T & CHD Exome+ Consortium 2018, ' Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity ', Nature Genetics, vol. 50, no. 1, pp. 26-41 . https://doi.org/10.1038/s41588-017-0011-x
Grarup, N, Hansen, T, Jørgensen, M E, Lin, L-A, Pedersen, O, Witte, D R, CHD Exome+ Consortium, EPIC-CVD Consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, EPIC InterAct Consortium, INTERVAL Study, ReproGen Consortium, T2D-Genes Consortium, MAGIC Investigators & Understanding Society Scientific Group 2018, ' Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity ', Nature Genetics, vol. 50, no. 1, pp. 26-41 . https://doi.org/10.1038/s41588-017-0011-x
Turcot, V, Lu, Y, Highland, H M, Schurmann, C, Justice, A E, Fine, R S, Kee, F, Hirschhorn, J N & Loos, R J F 2018, ' Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity ', Nature Genetics, vol. 50, pp. 26-41 . https://doi.org/10.1038/s41588-017-0011-x
Turcot, V, Lu, Y, Highland, H M, Schurmann, C, Justice, A E, Fine, R S, Bradfield, J P, Esko, T N, Giri, A, Graff, M, Guo, X, Hendricks, A E, Karaderi, T, Lempradl, A, Locke, A E, Mahajan, A, Marouli, E, Sivapalaratnam, S, Young, K L, Alfred, T, Feitosa, M F, Masca, N G D, Manning, A K, Medina-Gomez, C, Mudgal, P, Ng, M C Y, Reiner, A P, Vedantam, S, Willems, S M, Winkler, T W, Abecasis, G, Aben, K K, Alam, D S, Alharthi, S E, Allison, M, Amouyel, P, Asselbergs, F W, Auer, P L, Balkau, B, Bang, L E, Barroso, I, Bastarache, L, Benn, M, Bergmann, S, Bielak, L F, Blüher, M, Boehnke, M, Boeing, H, Boerwinkle, E, Böger, C A, Bork-Jensen, J, Bots, M L, Bottinger, E P, Bowden, D W, Brandslund, I, Breen, G, Brilliant, M H, Broer, L, Brumat, M, Burt, A A, Butterworth, A S, Campbell, P T, Cappellani, S, Carey, D J, Catamo, E, Caulfield, M J, Chambers, J C, Chasman, D I, Chen, Y-D I, Chowdhury, R, Christensen, C, Chu, A Y, Cocca, M, Cook, J P, Corley, J, Corominas Galbany, J, Cox, A J, Crosslin, D S, Cuellar-Partida, G, D'Eustacchio, A, Danesh, J, Davies, G, Bakker, P I W, Groot, M C H, Mutsert, R, Deary, I J, Dedoussis, G, Demerath, E W, Heijer, M, Hollander, A I, Ruijter, H M, Dennis, J G, Denny, J C, Angelantonio, E, Drenos, F, du, M, Dubé, M-P, Dunning, A M, Easton, D F, Edwards, T L, Ellinghaus, D, Ellinor, P T, Elliott, P, Evangelou, E, Farmaki, A-E, Farooqi, I S, Faul, J D, Fauser, S, Feng, S, Ferrannini, E, Ferrieres, J, Florez, J C, Ford, I, Fornage, M, Franco, O H, Franke, A, Franks, P W, Friedrich, N, Frikke-Schmidt, R, Galesloot, T E, Gan, W, Gandin, I, Gasparini, P, Gibson, J, Giedraitis, V, Gjesing, A P, Gordon-Larsen, P, Gorski, M, Grabe, H-J R, Grant, S F A, Grarup, N, Griffiths, H L, Grove, M L, Gudnason, V, Gustafsson, S, Haessler, J, Hakonarson, H, Hammerschlag, A R, Hansen, T, Harris, K M, Harris, T B, Hattersley, A T, Have, C T, Hayward, C, He, L, Heard-Costa, N L, Heath, A C, Heid, I M, Helgeland, Ø, Hernesniemi, J, Hewitt, A W, Holmen, O L, Hovingh, G K, Howson, J M M, Hu, Y, Huang, P L, Huffman, J E, Ikram, M A, Ingelsson, E, Jackson, A U, Jansson, J-H K, Jarvik, G P, Jensen, G B, Jia, Y, Johansson, S, Jørgensen, M E, Jørgensen, T, Jukema, J W, Kahali, B, Kahn, R S, Kähönen, M, Kamstrup, P R, Kanoni, S, Kaprio, J, Karaleftheri, M, Kardia, S L R, Karpe, F, Kathiresan, S, Kee, F, Kiemeney, L A, Kim, E, Kitajima, H, Komulainen, P, Kooner, J S, Kooperberg, C, Korhonen, T, Kovacs, P, Kuivaniemi, H, Kutalik, Z, Kuulasmaa, K, Kuusisto, J, Laakso, M, Lakka, T A, Lamparter, D, Lange, E M, Lange, L A, Langenberg, C, Larson, E B, Lee, N R, Lehtimäki, T, Lewis, C E, Li, H, Li, J, Li-Gao, R, Lin, H, Lin, K-H, Lin, L-A, Lin, X, Lind, L, Lindström, J, Linneberg, A, Liu, C-T, Liu, D J, Liu, Y, Lo, K S, Lophatananon, A, Lotery, A J, Loukola, A, Luan, JA, Lubitz, S A, Lyytikäinen, L-P, Männistö, S, Marenne, G, Mazul, A L, McCarthy, M I, McKean-Cowdin, R, Medland, S E, Meidtner, K, Milani, L, Mistry, V, Mitchell, P, Mohlke, K L, Moilanen, L, Moitry, M, Montgomery, G W, Mook-Kanamori, D O, Moore, C, Mori, T A, Morris, A D, Morris, A P, Müller-Nurasyid, M, Munroe, P B, Nalls, M A, Narisu, N, Nelson, C P, Neville, M, Nielsen, S F, Nikus, K, Njølstad, P L R, Nordestgaard, B R G, Nyholt, D R, O'Connel, J R, O'Donoghue, M L, Olde Loohuis, L M, Ophoff, R A, Owen, K R, Packard, C J, Padmanabhan, S, Palmer, C N A, Palmer, N D, Pasterkamp, G, Patel, A P, Pattie, A, Pedersen, O, Peissig, P L, Peloso, G M, Pennell, C E, Perola, M, Perry, J A, Perry, J R B, Pers, T H, Person, T N, Peters, A, Petersen, E R B, Peyser, P A, Pirie, A, Polasek, O, Polderman, T J, Puolijoki, H, Raitakari, O T, Rasheed, A, Rauramaa, R, Reilly, D F, Renström, F, Rheinberger, M, Ridker, P M, Rioux, J D, Rivas, M A, Roberts, D J, Robertson, N R, Robino, A, Rolandsson, O, Rudan, I, Ruth, K S, Saleheen, D, Salomaa, V, Samani, N J, Sapkota, Y, Sattar, N, Schoen, R E, Schreiner, P J, Schulze, M B, Scott, R A, Segura-Lepe, M P, Shah, S H, Sheu, W H-H, Sim, X, Slater, A J, Small, K S, Smith, A V, Southam, L, Spector, T D, Speliotes, E K, Starr, J M, Stefansson, K, Steinthorsdottir, V, Stirrups, K E, Strauch, K, Stringham, H M, Stumvoll, M, Sun, L, Surendran, P, Swift, A J, Tada, H, Tansey, K E, Tardif, J-C, Taylor, K D, Teumer, A, Thompson, D J, Thorleifsson, G, Thorsteinsdottir, U, Thuesen, B H, Tönjes, A, Tromp, G, Trompet, S, Tsafantakis, E, Tuomilehto, J, Tybjaerg-Hansen, A, Tyrer, J P, Uher, R, Uitterlinden, A G, Uusitupa, M, Laan, S W, Duijn, C M, Leeuwen, N, van Setten, J, Vanhala, M, Varbo, A, Varga, T V, Varma, R, Velez Edwards, D R, Vermeulen, S H, Veronesi, G, Vestergaard, H, Vitart, V, Vogt, T F, Völker, U, Vuckovic, D, Wagenknecht, L E, Walker, M, Wallentin, L, Wang, F, Wang, C A, Wang, S, Wang, Y, Ware, E B, Wareham, N J, Warren, H R, Waterworth, D M, Wessel, J, White, H D, Willer, C J, Wilson, J G, Witte, D R, Wood, A R, Wu, Y, Yaghootkar, H, Yao, J, Yao, P, Yerges-Armstrong, L M, Young, R, Zeggini, E, Zhan, X, Zhang, W, Zhao, J H, Zhao, W, Zhou, W, Zondervan, K T, Rotter, J I, Pospisilik, J A, Rivadeneira, F, Borecki, I B, Deloukas, P, Frayling, T M, Lettre, G, North, K E, Lindgren, C M, Hirschhorn, J N & Loos, R J F 2018, ' Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity ', Nature Genetics, vol. 50, no. 1, pp. 26-35 . https://doi.org/10.1038/s41588-017-0011-x
Nature Genetics, 50(1), 26. Nature Publishing Group
Nature Genetics
Nat. Genet. 50, 26-41 (2018)
Nature genetics, 50(1), 26-41. Nature Publishing Group
Nature Genetics, 50(1), 26-41. Nature Publishing Group
Nature genetics, vol. 50, no. 1, pp. 26-41
Nature Genetics, 50(1), 26
NATURE GENETICS
Nature genetics 50(1), 26-41 (2017). doi:10.1038/s41588-017-0011-x
Nature Genetics, 50, 26-41
Turcot, V, Lu, Y, Highland, H M, Schurmann, C, Justice, A E, Fine, R S, Bradfield, J P, Esko, T, Giri, A, Graff, M, Guo, X, Hendricks, A E, Karaderi, T, Lempradl, A, Locke, A E, Mahajan, A, Marouli, E, Sivapalaratnam, S, Young, K L, Alfred, T, Feitosa, M F, Masca, N G D, Manning, A K, Medina-Gomez, C, Mudgal, P, Ng, M C Y, Reiner, A P, Vedantam, S, Willems, S M, Winkler, T W, Abecasis, G, Aben, K K, Alam, D S, Alharthi, S E, Allison, M, Amouyel, P, Asselbergs, F W, Auer, P L, Balkau, B, Bang, L E, Barroso, I, Bastarache, L, Benn, M, Bergmann, S, Bielak, L F, Brandslund, I, Christensen, C, Jensen, G B, Jørgensen, M E, Thuesen, B H & CHD Exome+ Consortium 2018, ' Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity ', Nature Genetics, vol. 50, no. 1, pp. 26-41 . https://doi.org/10.1038/s41588-018-0050-y
Nature Genetics, 50(1), 26-35. Nature Publishing Group
Nature Genetics, 50, 1, pp. 26-41
Turcot, V, Lu, Y, Highland, H M, Schurmann, C, Justice, A E, Fine, R S, Bradfield, J P, Esko, T, Giri, A, Graff, M, Guo, X, Hendricks, A E, Karaderi, T, Lempradl, A, Locke, A E, Mahajan, A, Marouli, E, Sivapalaratnam, S, Young, K L, Alfred, T, Feitosa, M F, Masca, N G D, Manning, A K, Medina-Gomez, C, Mudgal, P, Ng, M C Y, Reiner, A P, Vedantam, S, Willems, S M, Winkler, T W, Abecasis, G, Aben, K K, Alam, D S, Alharthi, S E, Allison, M, Amouyel, P, Asselbergs, F W, Auer, P L, Balkau, B, Bang, L E, Barroso, I, Bastarache, L, Benn, M, Bergmann, S, Bielak, L F, Blüher, M, Boehnke, M, Boeing, H, Boerwinkle, E, Lophatananon, A, Morris, A & CHD Exome+ Consortium 2018, ' Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity ', Nature Genetics, vol. 50, no. 1, pp. 26-35 . https://doi.org/10.1038/s41588-017-0011-x
Turcot, V, Lu, Y, Highland, H M, Schurmann, C, Justice, A E, Fine, R S, Bradfield, J P, Esko, T, Giri, A, Graff, M, Guo, X, Hendricks, A E, Karaderi, T, Lempradl, A, Locke, A E, Mahajan, A, Marouli, E, Sivapalaratnam, S, Young, K L, Alfred, T, Feitosa, M F, Masca, N G D, Manning, A K, Medina-Gomez, C, Mudgal, P, Ng, M C Y, Reiner, A P, Vedantam, S, Willems, S M, Winkler, T W, Abecasis, G, Aben, K K, Alam, D S, Alharthi, S E, Allison, M, Amouyel, P, Asselbergs, F W, Auer, P L, Balkau, B, Bang, L E, Barroso, I, Bastarache, L, Benn, M, Bergmann, S, Bielak, L F, Blüher, M, Boehnke, M, Boeing, H, Hammerschlag, A R & Polderman, T J 2018, ' Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity ', Nature Genetics, vol. 50, no. 1, pp. 26-41 . https://doi.org/10.1038/s41588-017-0011-x
Turcot, V, Lu, Y, Highland, H M, Schurmann, C, Justice, A E, Fine, R S, Bradfield, J P, Esko, T, Giri, A, Graff, M, Guo, X, Hendricks, A E, Karaderi, T, Lempradl, A, Locke, A E, Mahajan, A, Marouli, E, Sivapalaratnam, S, Young, K L, Alfred, T, Feitosa, M F, Masca, N G D, Manning, A K, Medina-Gomez, C, Mudgal, P, Ng, M C Y, Reiner, A P, Vedantam, S, Willems, S M, Winkler, T W, Abecasis, G, Aben, K K, Alam, D S, Alharthi, S E, Allison, M, Amouyel, P, Asselbergs, F W, Auer, P L, Balkau, B, Bang, L E, Barroso, I, Bastarache, L, Benn, M, Bergmann, S, Bielak, L F, Blüher, M, Boehnke, M, Boeing, H, Boerwinkle, E, Jørgensen, T & CHD Exome+ Consortium 2018, ' Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity ', Nature Genetics, vol. 50, no. 1, pp. 26-41 . https://doi.org/10.1038/s41588-017-0011-x
Grarup, N, Hansen, T, Jørgensen, M E, Lin, L-A, Pedersen, O, Witte, D R, CHD Exome+ Consortium, EPIC-CVD Consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, EPIC InterAct Consortium, INTERVAL Study, ReproGen Consortium, T2D-Genes Consortium, MAGIC Investigators & Understanding Society Scientific Group 2018, ' Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity ', Nature Genetics, vol. 50, no. 1, pp. 26-41 . https://doi.org/10.1038/s41588-017-0011-x
Turcot, V, Lu, Y, Highland, H M, Schurmann, C, Justice, A E, Fine, R S, Kee, F, Hirschhorn, J N & Loos, R J F 2018, ' Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity ', Nature Genetics, vol. 50, pp. 26-41 . https://doi.org/10.1038/s41588-017-0011-x
Turcot, V, Lu, Y, Highland, H M, Schurmann, C, Justice, A E, Fine, R S, Bradfield, J P, Esko, T N, Giri, A, Graff, M, Guo, X, Hendricks, A E, Karaderi, T, Lempradl, A, Locke, A E, Mahajan, A, Marouli, E, Sivapalaratnam, S, Young, K L, Alfred, T, Feitosa, M F, Masca, N G D, Manning, A K, Medina-Gomez, C, Mudgal, P, Ng, M C Y, Reiner, A P, Vedantam, S, Willems, S M, Winkler, T W, Abecasis, G, Aben, K K, Alam, D S, Alharthi, S E, Allison, M, Amouyel, P, Asselbergs, F W, Auer, P L, Balkau, B, Bang, L E, Barroso, I, Bastarache, L, Benn, M, Bergmann, S, Bielak, L F, Blüher, M, Boehnke, M, Boeing, H, Boerwinkle, E, Böger, C A, Bork-Jensen, J, Bots, M L, Bottinger, E P, Bowden, D W, Brandslund, I, Breen, G, Brilliant, M H, Broer, L, Brumat, M, Burt, A A, Butterworth, A S, Campbell, P T, Cappellani, S, Carey, D J, Catamo, E, Caulfield, M J, Chambers, J C, Chasman, D I, Chen, Y-D I, Chowdhury, R, Christensen, C, Chu, A Y, Cocca, M, Cook, J P, Corley, J, Corominas Galbany, J, Cox, A J, Crosslin, D S, Cuellar-Partida, G, D'Eustacchio, A, Danesh, J, Davies, G, Bakker, P I W, Groot, M C H, Mutsert, R, Deary, I J, Dedoussis, G, Demerath, E W, Heijer, M, Hollander, A I, Ruijter, H M, Dennis, J G, Denny, J C, Angelantonio, E, Drenos, F, du, M, Dubé, M-P, Dunning, A M, Easton, D F, Edwards, T L, Ellinghaus, D, Ellinor, P T, Elliott, P, Evangelou, E, Farmaki, A-E, Farooqi, I S, Faul, J D, Fauser, S, Feng, S, Ferrannini, E, Ferrieres, J, Florez, J C, Ford, I, Fornage, M, Franco, O H, Franke, A, Franks, P W, Friedrich, N, Frikke-Schmidt, R, Galesloot, T E, Gan, W, Gandin, I, Gasparini, P, Gibson, J, Giedraitis, V, Gjesing, A P, Gordon-Larsen, P, Gorski, M, Grabe, H-J R, Grant, S F A, Grarup, N, Griffiths, H L, Grove, M L, Gudnason, V, Gustafsson, S, Haessler, J, Hakonarson, H, Hammerschlag, A R, Hansen, T, Harris, K M, Harris, T B, Hattersley, A T, Have, C T, Hayward, C, He, L, Heard-Costa, N L, Heath, A C, Heid, I M, Helgeland, Ø, Hernesniemi, J, Hewitt, A W, Holmen, O L, Hovingh, G K, Howson, J M M, Hu, Y, Huang, P L, Huffman, J E, Ikram, M A, Ingelsson, E, Jackson, A U, Jansson, J-H K, Jarvik, G P, Jensen, G B, Jia, Y, Johansson, S, Jørgensen, M E, Jørgensen, T, Jukema, J W, Kahali, B, Kahn, R S, Kähönen, M, Kamstrup, P R, Kanoni, S, Kaprio, J, Karaleftheri, M, Kardia, S L R, Karpe, F, Kathiresan, S, Kee, F, Kiemeney, L A, Kim, E, Kitajima, H, Komulainen, P, Kooner, J S, Kooperberg, C, Korhonen, T, Kovacs, P, Kuivaniemi, H, Kutalik, Z, Kuulasmaa, K, Kuusisto, J, Laakso, M, Lakka, T A, Lamparter, D, Lange, E M, Lange, L A, Langenberg, C, Larson, E B, Lee, N R, Lehtimäki, T, Lewis, C E, Li, H, Li, J, Li-Gao, R, Lin, H, Lin, K-H, Lin, L-A, Lin, X, Lind, L, Lindström, J, Linneberg, A, Liu, C-T, Liu, D J, Liu, Y, Lo, K S, Lophatananon, A, Lotery, A J, Loukola, A, Luan, JA, Lubitz, S A, Lyytikäinen, L-P, Männistö, S, Marenne, G, Mazul, A L, McCarthy, M I, McKean-Cowdin, R, Medland, S E, Meidtner, K, Milani, L, Mistry, V, Mitchell, P, Mohlke, K L, Moilanen, L, Moitry, M, Montgomery, G W, Mook-Kanamori, D O, Moore, C, Mori, T A, Morris, A D, Morris, A P, Müller-Nurasyid, M, Munroe, P B, Nalls, M A, Narisu, N, Nelson, C P, Neville, M, Nielsen, S F, Nikus, K, Njølstad, P L R, Nordestgaard, B R G, Nyholt, D R, O'Connel, J R, O'Donoghue, M L, Olde Loohuis, L M, Ophoff, R A, Owen, K R, Packard, C J, Padmanabhan, S, Palmer, C N A, Palmer, N D, Pasterkamp, G, Patel, A P, Pattie, A, Pedersen, O, Peissig, P L, Peloso, G M, Pennell, C E, Perola, M, Perry, J A, Perry, J R B, Pers, T H, Person, T N, Peters, A, Petersen, E R B, Peyser, P A, Pirie, A, Polasek, O, Polderman, T J, Puolijoki, H, Raitakari, O T, Rasheed, A, Rauramaa, R, Reilly, D F, Renström, F, Rheinberger, M, Ridker, P M, Rioux, J D, Rivas, M A, Roberts, D J, Robertson, N R, Robino, A, Rolandsson, O, Rudan, I, Ruth, K S, Saleheen, D, Salomaa, V, Samani, N J, Sapkota, Y, Sattar, N, Schoen, R E, Schreiner, P J, Schulze, M B, Scott, R A, Segura-Lepe, M P, Shah, S H, Sheu, W H-H, Sim, X, Slater, A J, Small, K S, Smith, A V, Southam, L, Spector, T D, Speliotes, E K, Starr, J M, Stefansson, K, Steinthorsdottir, V, Stirrups, K E, Strauch, K, Stringham, H M, Stumvoll, M, Sun, L, Surendran, P, Swift, A J, Tada, H, Tansey, K E, Tardif, J-C, Taylor, K D, Teumer, A, Thompson, D J, Thorleifsson, G, Thorsteinsdottir, U, Thuesen, B H, Tönjes, A, Tromp, G, Trompet, S, Tsafantakis, E, Tuomilehto, J, Tybjaerg-Hansen, A, Tyrer, J P, Uher, R, Uitterlinden, A G, Uusitupa, M, Laan, S W, Duijn, C M, Leeuwen, N, van Setten, J, Vanhala, M, Varbo, A, Varga, T V, Varma, R, Velez Edwards, D R, Vermeulen, S H, Veronesi, G, Vestergaard, H, Vitart, V, Vogt, T F, Völker, U, Vuckovic, D, Wagenknecht, L E, Walker, M, Wallentin, L, Wang, F, Wang, C A, Wang, S, Wang, Y, Ware, E B, Wareham, N J, Warren, H R, Waterworth, D M, Wessel, J, White, H D, Willer, C J, Wilson, J G, Witte, D R, Wood, A R, Wu, Y, Yaghootkar, H, Yao, J, Yao, P, Yerges-Armstrong, L M, Young, R, Zeggini, E, Zhan, X, Zhang, W, Zhao, J H, Zhao, W, Zhou, W, Zondervan, K T, Rotter, J I, Pospisilik, J A, Rivadeneira, F, Borecki, I B, Deloukas, P, Frayling, T M, Lettre, G, North, K E, Lindgren, C M, Hirschhorn, J N & Loos, R J F 2018, ' Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity ', Nature Genetics, vol. 50, no. 1, pp. 26-35 . https://doi.org/10.1038/s41588-017-0011-x
Nature Genetics, 50(1), 26. Nature Publishing Group
Nature Genetics
Nat. Genet. 50, 26-41 (2018)
Nature genetics, 50(1), 26-41. Nature Publishing Group
Nature Genetics, 50(1), 26-41. Nature Publishing Group
Nature genetics, vol. 50, no. 1, pp. 26-41
Nature Genetics, 50(1), 26
NATURE GENETICS
Nature genetics 50(1), 26-41 (2017). doi:10.1038/s41588-017-0011-x
Nature Genetics, 50, 26-41
Turcot, V, Lu, Y, Highland, H M, Schurmann, C, Justice, A E, Fine, R S, Bradfield, J P, Esko, T, Giri, A, Graff, M, Guo, X, Hendricks, A E, Karaderi, T, Lempradl, A, Locke, A E, Mahajan, A, Marouli, E, Sivapalaratnam, S, Young, K L, Alfred, T, Feitosa, M F, Masca, N G D, Manning, A K, Medina-Gomez, C, Mudgal, P, Ng, M C Y, Reiner, A P, Vedantam, S, Willems, S M, Winkler, T W, Abecasis, G, Aben, K K, Alam, D S, Alharthi, S E, Allison, M, Amouyel, P, Asselbergs, F W, Auer, P L, Balkau, B, Bang, L E, Barroso, I, Bastarache, L, Benn, M, Bergmann, S, Bielak, L F, Brandslund, I, Christensen, C, Jensen, G B, Jørgensen, M E, Thuesen, B H & CHD Exome+ Consortium 2018, ' Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity ', Nature Genetics, vol. 50, no. 1, pp. 26-41 . https://doi.org/10.1038/s41588-018-0050-y
Nature Genetics, 50(1), 26-35. Nature Publishing Group
Nature Genetics, 50, 1, pp. 26-41
Genome-wide association studies (GWAS) have identified >250 loci for body mass index (BMI), implicating pathways related to neuronal biology. Most GWAS loci represent clusters of common, noncoding variants from which pinpointing causal genes remains
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https://explore.openaire.eu/search/publication?articleId=doi_dedup___::247d0a0f65cfe65a4234fc1f8f72fc1d
https://doi.org/10.1038/s41588-017-0011-x
https://doi.org/10.1038/s41588-017-0011-x