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Publikováno v:
Bioinformatics. 27:3002-3009
Motivation: Accurate binding free energy functions for protein–protein interactions are imperative for a wide range of purposes. Their construction is predicated upon ascertaining the factors that influence binding and their relative importance. A
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 9, p e1003216 (2013)
RIUR. Repositorio Institucional de la Universidad de La Rioja
instname
PLoS Computational Biology
RIUR. Repositorio Institucional de la Universidad de La Rioja
instname
PLoS Computational Biology
Predicting the effects of mutations on the kinetic rate constants of protein-protein interactions is central to both the modeling of complex diseases and the design of effective peptide drug inhibitors. However, while most studies have concentrated o