Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jae J. Song"'
Autor:
Hye Jin Choi, Soo Jin Choi, Dongxu Kang, Geun-Hyeok Oh, Zhezhu Han, Suwan Ko, Suyeon Je, Jihyun Lee, Jae J. Song, Yeonsoo Joo
Publikováno v:
Experimental and Molecular Medicine, Vol 50, Iss 12, Pp 1-19 (2018)
Experimental & Molecular Medicine
Experimental & Molecular Medicine
Transforming growth factor (TGF)-β signaling is increasingly recognized as a key driver in cancer. In progressive cancer tissues, TGF-β promotes tumor formation, and its increased expression often correlates with cancer malignancy. In this study, w
Autor:
Bo K. Sun, Jae J. Song, Jina Kim, Hyo R. Yoon, Joo Hang Kim, So Y. Kim, Dongxu Kang, Sujin Kang
Publikováno v:
Cellular Signalling. 24:1444-1452
The combination of curcumin and TRAIL and their role in enhancing apoptotic cell death has been reported by many studies. However, the exact molecular mechanism of apoptosis mediated by curcumin and tumor necrosis factor-related apoptosis-inducing li
Autor:
Marco A. Alcala, Yong Tae Kwon, Miroslaw J. Szczepanski, Joo Hang Kim, So Young Kim, Jee Young An, David L. Bartlett, Yong J. Lee, Jae J. Song
Publikováno v:
Cellular Signalling. 22:553-563
We previously reported two modes of development of acquired TRAIL resistance: early phase and late phase [1]. In these studies, we observed that greater Akt activity and the expression of Bcl-xL were related mainly to the late phase of acquired TRAIL
Publikováno v:
Cellular signalling. 25(1)
Previously, we showed that mitogen-activated protein kinase/extracellular signal-related kinase 4 (MEKK4) is responsible for p38 activation and that its activation during tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) treatment also
We have previously observed that TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) induces acquired TRAIL resistance by increasing Akt phosphorylation and Bcl-xL expression. In this study, we report that Src, c-Cbl, and PI3K are involve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a051ad1b1f43151b19b67b005d5126
https://europepmc.org/articles/PMC2965849/
https://europepmc.org/articles/PMC2965849/
Autor:
Hyeong Reh Choi Kim, Jin H. Kim, Douglas R. Spitz, Jae J. Song, Young K. Song, Anna Lokshin, Yong J. Lee, Ling Li, R. Rita Siervo-Sassi
Publikováno v:
Experimental cell research. 288(1)
We investigated the role of galectin-3 in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptotic death in human breast carcinoma BT549 cells. We observed that parental galectin-3 null BT549 cells (BT549(par)) as well as con
Publikováno v:
Cancer Research. 73:2957-2957
TRAIL-induced activation of Akt catalytic activity and phosphorylation were highly correlated with p38/HSP27 phosphorylation, whereas the phosphorylation of p38/HSP27 increased further during incubation with curcumin and TRAIL, which caused significa
Autor:
So Y. Kim, Joo Hang Kim, Wungki Park, Jae J. Song, Jina Kim, Hyo R. Yoon, Kijae Hong, Hye Jin Choi, Seeun Oh, Sujin Kang
Publikováno v:
Cancer Research. 71:C42-C42
Previously, we have shown that p38-HSP27 acted as modulators from survival to death depending on the apoptotic strength in prostate cancer cells. For example, if the apoptotic strength is in the moderate range, p38-HSP27 acted to increase Akt catalyt
Publikováno v:
Cancer Research. 71:4104-4104
Previously, we demonstrated that TRAIL-induced p38 activation was responsible for the increases of Akt catalytic and invasive activity. Interestingly, TRAIL induced dramatically Akt catalytic activation in TRAIL-sensitive cells, whereas TRAIL did not
Autor:
Yong J. Lee, Joo Hang Kim, Hye Jin Choi, Bo K. Sun, So Y. Kim, Joohyuk Sohn, Seeun Oh, Jae J. Song
Publikováno v:
Cancer Research. 70:1276-1276
In this paper, we demonstrate that TRAIL-induced p38 activation is responsible for the increases of Akt catalytic activity and invasive activity. For the confirmation of increases of Akt catalytic and invasive activity induced by TRAIL-induced p38 ac