Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Dolph L. Hatfield"'
Autor:
Ulrich Schweizer, Sandra Seeher, Michael T. Howard, Dolph L. Hatfield, Christine B. Anderson, Michael Doengi, Bradley A. Carlson, Noelia Fradejas-Villar
Publikováno v:
Nucleic Acids Research
Dual-assignment of codons as termination and elongation codons is used to expand the genetic code. In mammals, UGA can be reassigned to selenocysteine during translation of selenoproteins by a mechanism involving a 3΄ untranslated region (UTR) selen
Autor:
Bradley A, Carlson, Byeong Jae, Lee, Petra A, Tsuji, Paul R, Copeland, Ulrich, Schweizer, Vadim N, Gladyshev, Dolph L, Hatfield
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1661
The selenocysteine (Sec) tRNA[Ser]Sec population consists of two isoforms that differ from each other by a single 2’-O-methylribosyl moiety at position 34 (Um34). These two isoforms, which are encoded in a single gene, Trsp, and modified post-trans
Autor:
Anton A. Turanov, Vadim N. Gladyshev, Ryuta Tobe, Steven P. Gygi, Petra A. Tsuji, Robert A. Everley, Salvador Naranjo-Suarez, Min-Hyuk Yoo, Bradley A. Carlson, Dolph L. Hatfield
Publikováno v:
Journal of Biological Chemistry. 288:14709-14715
Antibiotics target bacteria by interfering with essential processes such as translation, but their effects on translation in mammalian cells are less well characterized. We found that doxycycline, chloramphenicol, and Geneticin (G418) interfered with
Autor:
Odelia Rajanayagam, Nadia Schoenmakers, Bradley A. Carlson, Erik Schoenmakers, Rachel Peat, Francesco Muntoni, Maura Agostini, Evelien F. Gevers, Pascale Guicheney, Ryuta Tobe, Greta Lyons, Krishna Chatterjee, Carla Moran, Sadaf Farooqi, Dolph L. Hatfield, Elena G. Bochukova
Publikováno v:
Journal of Clinical Investigation
Journal of Clinical Investigation, 2016, 126 (3), pp.992-996. ⟨10.1172/JCI84747⟩
Journal of Clinical Investigation, American Society for Clinical Investigation, 2016, 126 (3), pp.992-996. ⟨10.1172/JCI84747⟩
Journal of Clinical Investigation, 2016, 126 (3), pp.992-996. ⟨10.1172/JCI84747⟩
Journal of Clinical Investigation, American Society for Clinical Investigation, 2016, 126 (3), pp.992-996. ⟨10.1172/JCI84747⟩
International audience; Selenium is a trace element that is essential for human health and is incorporated into more than 25 human selenocysteine-containing (Sec-containing) proteins via unique Sec-insertion machinery that includes a specific, nuclea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b564f713cffd43e17bc6acb51e4ba5
https://hal.sorbonne-universite.fr/hal-01295150
https://hal.sorbonne-universite.fr/hal-01295150
Autor:
Dolph L. Hatfield, Ulrich Schweizer, Petra A. Tsuji, Bradley A. Carlson, Jin Mo Park, Ryuta Tobe, Vadim N. Gladyshev, Byeong Jae Lee
Publikováno v:
Selenium ISBN: 9783319412818
When selenocysteine (Sec) tRNA[Ser]Sec was originally discovered, it was proposed to be the first nonsense suppressor tRNA found in mammalian and avian tissues, since it exclusively decoded the nonsense codon, UGA, which normally dictates the cessati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed602aa9a6604a4ea617e627c8b01cf7
https://doi.org/10.1007/978-3-319-41283-2_1
https://doi.org/10.1007/978-3-319-41283-2_1
Autor:
Judith G. Levin, Alan Rein, Ya-Xiong Feng, Dolph L. Hatfield, Byeong J. Lee, Stephen Oroszlan
Publikováno v:
Virology
An examination of the frameshift signals or proposed signals within published sequences of retroviruses and other genetic elements from higher animals shows that each site utilizes a tRNA which normally contains Wybutoxine (Wye) base or Queuine (Q) b
Autor:
Ulrich Schweizer, Markus Brielmeier, Marcus Conrad, Dolph L. Hatfield, B. Suman Bharathi, Eva K. Wirth
Publikováno v:
Biological Trace Element Research
Selenium exerts many, if not most, of its physiological functions as a selenocysteine moiety in proteins. Selenoproteins are involved in many biochemical processes including regulation of cellular redox state, calcium homeostasis, protein biosynthesi
Autor:
M. A. El-Saadani, Gerald F. Combs, Byeong Jae Lee, Lionel Feigenbaum, Vadim N. Gladyshev, Qi An Sun, Raymond F. Burk, John W. Harney, Marla J. Berry, Dolph L. Hatfield, Mohamed E. Moustafa, Kristina E. Hill, Gregory V. Kryukov, Alan M. Diamond, Bradley A. Carlson, David B. Mansur
Publikováno v:
Molecular and Cellular Biology. 21:3840-3852
Selenocysteine (Sec) tRNA (tRNA([Ser]Sec)) serves as both the site of Sec biosynthesis and the adapter molecule for donation of this amino acid to protein. The consequences on selenoprotein biosynthesis of overexpressing either the wild type or a mut
Autor:
Glover W. Martin, Elisabeth Grundner-Culemann, Susan C. Low, John W. Harney, Bradley A. Carlson, Paul R. Copeland, Donna M. Driscoll, Marla J. Berry, John B. Mansell, Dolph L. Hatfield, Xue-Ming Xu, Rosa M. Tujebajeva
Publikováno v:
BioFactors. 14:17-24
The mechanism of selenocysteine incorporation in eukaryotes has been assumed for almost a decade to be inherently different from that in prokaryotes, due to differences in the architecture of selenoprotein mRNAs in the two kingdoms. After extensive e
Autor:
Jerry R. Faust, Gregory J. Warner, Marla J. Berry, Dolph L. Hatfield, Mohamed E. Moustafa, Bradley A. Carlson
Publikováno v:
Journal of Biological Chemistry. 275:28110-28119
A common posttranscriptional modification of tRNA is the isopentenylation of adenosine at position 37, creating isopentenyladenosine (i(6)A). The role of this modified nucleoside in protein synthesis of higher eukaryotes is not well understood. Selen