Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Songbo Xie"'
Autor:
Dan Dong, Linlin Zhang, Ruixin Ge, Cunxian Fan, Qianqian He, Wei Xie, Min Liu, Songbo Xie, Dengwen Li, Jun Zhou
Publikováno v:
J Biol Chem
Tripartite motif–containing protein 21 (TRIM21) is a cytosolic antibody receptor that targets the internalized virus–antibody complex to the proteasome for degradation. However, the precise mechanism regulating TRIM21 activity is unknown. Here we
Autor:
Lihong Yang, Qingchao Li, Te Li, Tao Zhong, Wei Xie, Yan Zhang, Min Liu, Jun Zhou, Song Yang, Jie Feng, Dengwen Li, Xianfei He, Songbo Xie
Publikováno v:
Experimental cell research. 387(1)
Microtubule-binding proteins provide an alternative and vital pathway to the functional diversity of microtubules. Considerable work is still required to understand the complexities of microtubule-associated cellular processes and to identify novel m
Autor:
Ruming Liu, Ziwei Hao, Min Liu, Juan Qin, Jun Zhou, Songbo Xie, Yunqiang Zhou, Xin Du, Xinqi Liu, Dengwen Li
Publikováno v:
Oncotarget
// Juan Qin 1 , Dengwen Li 1 , Yunqiang Zhou 1 , Songbo Xie 2 , Xin Du 2 , Ziwei Hao 1 , Ruming Liu 1 , Xinqi Liu 1 , Min Liu 2 , Jun Zhou 1, 2 1 State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials of the Ministr
Autor:
Qiang Chen, Dan Dong, Wei Xie, Min Liu, Jun Zhou, Dengwen Li, Yijun Zhang, Youguang Luo, Zhenhua Zhang, Xin Xiao, Songbo Xie, Yu Cao, Miao Chen, Jie Chen
Publikováno v:
Experimental Cell Research. 384:111618
End binding protein 1 (EB1) is a key regulator of microtubule dynamics that orchestrates hierarchical interaction networks at microtubule plus ends to control proper cell division. EB1 activity is known to be regulated by serine/threonine phosphoryla
Publikováno v:
Journal of cellular physiology. 233(3)
Microtubule plus ends undergo highly dynamic modifications to regulate different aspects of cellular activities. Most microtubule plus-end tracking proteins (+TIPs) are recruited to the microtubule ends by the master loading factor, end-binding prote
Publikováno v:
Biochemical and Biophysical Research Communications. 447:465-470
Eg5 is a mitotic kinesin that plays a crucial role in the formation of bipolar mitotic spindles, by hydrolyzing ATP to push apart anti-parallel microtubules. Dimethylenastron is potent specific small molecule inhibitor of Eg5. The mechanism by which
Publikováno v:
Protein & Cell
Pancreatic cancer is a devastating disease with the worst prognosis among all the major human malignancies. The propensity to rapidly metastasize contributes significantly to the highly aggressive feature of pancreatic cancer. The molecular mechanism