Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Raul Araya-Secchi"'
Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception
Autor:
Yoshie Narui, Marcos Sotomayor, Elakkiya Tamilselvan, Pedro De-la-Torre, Carissa F. Klanseck, Conghui Chen, Deepanshu Choudhary, Raul Araya-Secchi, Lahiru N. Wimalasena, Brandon L. Neel
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Choudhary, D, Narui, Y, Neel, B L, Wimalasena, L N, Klanseck, C F, De-la-Torre, P, Chen, C, Araya-Secchi, R, Tamilselvan, E & Sotomayor, M 2020, ' Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception ', Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 40, pp. 24837-24848 . https://doi.org/10.1073/pnas.1920444117
Choudhary, D, Narui, Y, Neel, B L, Wimalasena, L N, Klanseck, C F, De-la-Torre, P, Chen, C, Araya-Secchi, R, Tamilselvan, E & Sotomayor, M 2020, ' Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception ', Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 40, pp. 24837-24848 . https://doi.org/10.1073/pnas.1920444117
Significance When sound vibrations reach the inner ear, fine protein filaments called “tip links” stretch and open cochlear hair-cell mechanosensitive channels that trigger sensory perception. Similarly, vestibular hair cells use tip links to sen
Publikováno v:
Biophys J
Cadherins are a superfamily of adhesion proteins involved in a variety of biological processes that include the formation of intercellular contacts, the maintenance of tissue integrity, and the development of neuronal circuits. These transmembrane pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01162f70a6fadd83e969e1b733d72a20
https://doi.org/10.1101/2021.07.29.454067
https://doi.org/10.1101/2021.07.29.454067
Autor:
Nanditha Shyam Prasad, Jens Vogensen, Stine F. Pedersen, Marité Cárdenas, Ruth Hendus-Altenburger, Birthe B. Kragelund, Elena Pedraz-Cuesta, Emilie S Pedersen, Raul Araya-Secchi, Anne H. Bendsoe, Alessandra Luchini, Lise Arleth, Andreas Prestel
Publikováno v:
Hendus-Altenburger, R, Vogensen, J, Pedersen, E S, Luchini, A, Araya-Secchi, R, Bendsoe, A H, Prasad, N S, Prestel, A, Cardenas, M, Pedraz-Cuesta, E, Arleth, L, Pedersen, S H F & Kragelund, B B 2020, ' The intracellular lipid-binding domain of human Na + /H + exchanger 1 forms a lipid-protein co-structure essential for activity ', Communications Biology, vol. 3, no. 1, 731 . https://doi.org/10.1038/s42003-020-01455-6
Communications Biology
Communications Biology
Dynamic interactions of proteins with lipid membranes are essential regulatory events in biology, but remain rudimentarily understood and particularly overlooked in membrane proteins. The ubiquitously expressed membrane protein Na+/H+-exchanger 1 (NH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::334005090442e757ab4e4672536ac7b8
http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-37152
http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-37152
Publikováno v:
Scientific Reports
Cancer metastasis is an important criterion to evaluate tumor malignancy. Matrix metalloproteinases (MMPs) play a crucial role in cancer proliferation and migration by virtue of their proteolytic functions in angiogenesis and extracelluar matrix (ECM
Autor:
Raul Araya-Secchi, Cristian O. Salas, Tomas Perez-Acle, Carlos F. Lagos, Pablo Thomas, Ricardo A. Tapia
Publikováno v:
Journal of molecular modeling. 18(5)
Trypanosoma cruzi glutamate cysteine ligase (TcGCL) is considered a potential drug target to develop novel antichagasic drugs. We have used a variety of computational methods to investigate the interactions between TcGCL with Glutathione (GSH). The t