Zobrazeno 241 - 250
of 269
pro vyhledávání: '"Angelo M. De Marzo"'
Publikováno v:
Cancer Discovery. 2:206-207
Ubiquitin-specific protease 2a (USP2a) is overexpressed in almost half of human prostate cancers and c-Myc is amplified in one third of these tumor types. Transgenic MYC expression drives invasive adenocarcinomas in the murine prostate. We show that
Autor:
Thomas W. Kensler, Xiaohui Lin, Chad P. Nelson, James D. Brooks, Matthew J. Putzi, Theodore L. DeWeese, William G. Nelson, John D. Groopman, Angelo M. De Marzo
Publikováno v:
Annals of the New York Academy of Sciences. 952
Environmental factors, especially the diet, play a prominent role in the epidemic of prostate cancer (PCA), in the United States. Many candidate dietary components have been proposed to influence human prostatic carcinogenesis, including fat, calorie
Autor:
Jeffrey C. Roeser, Emmanuel S. Antonarakis, Mary Nakazawa, Channing J. Paller, Helen L. Fedor, Angelo M. De Marzo, Samuel R. Denmeade, Rosa Nadal, Mario A. Eisenberger, Michael A. Carducci, Jun Luo, Qizhi Zheng, Changxue Lu, John T. Isaacs, Hao Wang, Tamara L. Lotan, Yan Chen, William B. Isaacs, Brandon Luber
Publikováno v:
Journal of Clinical Oncology. 32:5001-5001
5001 Background: Androgen receptor splice variant-7 (AR-V7) is a truncated form of the androgen receptor that lacks the ligand-binding domain, the target of enzalutamide and abiraterone, but remain...
Publikováno v:
Urology. 57(4 Suppl 1)
The development of drugs to prevent prostate cancer is underway, yet monitoring the potential efficacy of these agents during clinical trials relies on measuring intermediate endpoints. In this review, various candidate markers are presented that are
Autor:
Meir J. Stampfer, Christopher M. Heaphy, Alan K. Meeker, Edward L. Giovanucci, Sarah B. Peskoe, Ghil Suk Yoon, Jessica L. Hicks, Angelo M. De Marzo, Stacey A. Kenfield, Thomas K. Lee, Elizabeth A. Platz, Corinne E. Joshu, Lorelei A. Mucci
Publikováno v:
Cancer Prevention Research. 6:PR06-PR06
Background: Meta-analyses and some cohort studies support that obese men are more likely to develop high-grade and advanced stage prostate cancer, recur after treatment, and die of this cancer. Physical activity, independent of body mass index, has b
Autor:
Charles G. Drake, Angelo M. De Marzo, Jianfeng Xu, Alan W. Partin, Misop Han, Ming-Hsi Wang, Elizabeth A. Platz, Siqun L. Zheng, Helen L. Fedor, William B. Isaacs
Publikováno v:
Journal of Urology. 181:167-168
Publikováno v:
Urology. 53(4)
Approximately 30% of clinically localized prostate adenocarcinomas treated by radical prostatectomy (RP) will recur within 10 years. To prevent recurrence, new adjuvant therapies are in development that seek to treat high-risk patients after surgery.
Autor:
Angelo M. De Marzo
Publikováno v:
Urologic Oncology: Seminars and Original Investigations. 25:240-241
Autor:
William G. Nelson, Christopher Weier, David M. Esopi, Michael C. Haffner, Jessica Hicks, Angelo M. De Marzo, William B. Isaacs, Srinivasan Yegnasubramanian, Qizhi Zheng, Timothy Mosbruger
Publikováno v:
Cancer Research. 73:1773-1773
TMPRSS2-ERG translocations occur in approximately 50% of prostate cancers and therefore represent one of the most frequently observed structural rearrangements in all cancers. However, little is known about the genomic architecture of such rearrangem
Autor:
Charles G. Drake, Nrupen A. Bhavsar, William B. Isaacs, Angelo M. De Marzo, Alan K. Meeker, Sarah B. Peskoe, Jay J. Bream, Elizabeth A. Platz
Publikováno v:
Cancer Research. 73:3618-3618
Background Recent evidence suggests a role for inflammation in the etiology of prostate cancer. Cytokines are important regulators of immune response, including in cancer. In the context of cancer, Th1 cytokines, such as interferon gamma (IFN-γ), tu