Zobrazeno 11 - 20
of 269
pro vyhledávání: '"Angelo M. De Marzo"'
Autor:
William G. Nelson, Michael T. Marrone, Berrak Gumuskaya, Charles G. Drake, Fan Pan, Ian M. Thompson, Ibrahim Kulac, Jun O. Liu, Phyllis J. Goodman, Ines Benedetti, Lauren M. Hurwitz, M. Scott Lucia, Elizabeth A. Platz, Angelo M. De Marzo, Catherine M. Tangen, Javier A. Baena Del Valle, William B. Isaacs, Kathryn B. Arnold
Publikováno v:
Cancer Prev Res (Phila)
Aspirin and statin use may lower the risk of advanced/fatal prostate cancer, possibly by reducing intraprostatic inflammation. To test this hypothesis, we investigated the association of aspirin and statin use with the presence and extent of intrapro
Autor:
Susan L. Dalrymple, Yezi Zhu, Peter S. Nelson, Jun Luo, Jianfeng Xu, Alan K. Meeker, Samuel R. Denmeade, Emmanuel S. Antonarakis, S. Lilly Zheng, William B. Isaacs, Angelo M. De Marzo, Jody E. Hooper, Ilsa Coleman, John T. Isaacs, W. Nathaniel Brennen
Publikováno v:
Oncogene
The role of truncated androgen receptor splice variant-7 (AR-V7) in prostate cancer biology is an unresolved question. Is it simply a marker of resistance to 2nd-generation androgen receptor signaling inhibitors (ARSi) like abiraterone acetate (Abi)
Autor:
Kirsten Timms, Emmanuel S. Antonarakis, Jessica Hicks, Colin C. Pritchard, Bruce J. Trock, Angelo M. De Marzo, Tamara L. Lotan, Daniela C. Salles, Harsimar B. Kaur, William B. Isaacs, Minh Nguyen, Jerry S. Lanchbury, Sanjana Murali
Publikováno v:
Clinical Cancer Research. 26:4869-4881
Purpose:The ATM (ataxia telangiectasia mutated) gene is mutated in a subset of prostate cancers, and ATM mutation may confer specific therapeutic vulnerabilities, although ATM-deficient prostate cancers have not been well-characterized.Experimental D
Autor:
Srinivasan Yegnasubramanian, Janis M. Taube, Angelo M. De Marzo, Busra Ozbek, Carolina Gomes Alexandre, Onur Ertunc, Tracy Jones, Andrew Erickson, Jessica L. Hicks, Karen S. Sfanos, Gunes Guner, Igor Vidal
Background Most prostate cancers are "immune cold" and poorly responsive to immune checkpoint inhibitors. However, the mechanisms responsible for the lack of a robust antitumor adaptive immune response in the prostate are poorly understood, which hin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c591f71687247183a020de67df431d23
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/96552
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/96552
Autor:
Jody E. Hooper, Susan L. Dalrymple, Samuel R. Denmeade, Yezi Zhu, Angelo M. De Marzo, W. Nathaniel Brennen, S. Lilly Zheng, Peter S. Nelson, Ilsa Coleman, John T. Isaacs, Jun Luo, Alan K. Meeker, Jianfeng Xu, Emmanuel S. Antonarakis, William B. Isaacs
Publikováno v:
Oncogene. 40:3914-3916
Autor:
David Lim, Mindy K. Graham, Eva Corey, Tamara L. Lotan, Jonathan I. Epstein, Alan K. Meeker, Christopher M. Heaphy, Hao Wang, Mario A. Eisenberger, Angelo M. De Marzo, Christine Davis, Michael C. Haffner
Publikováno v:
Hum Pathol
BACKGROUND: Small cell neuroendocrine carcinoma (SCNC) of the prostate is an aggressive subtype with frequent TP53 mutation and RB1 inactivation, however the molecular phenotype remains an area of investigation. Here, we compared telomere lengths in
Autor:
Angelo M. De Marzo, Howard L. Parnes, Bora Gurel, M. Scott Lucia, Scott M. Lippman, Phyllis J. Goodman, Elizabeth A. Platz, John R. Barber, Frank Z. Stanczyk, William G. Nelson, Susan Chadid, Ian M. Thompson
Publikováno v:
Prostate
Background Intraprostatic inflammation is an emerging prostate cancer risk factor. Estrogens are pro-inflammatory while androgens are anti-inflammatory. Thus, we investigated whether serum sex steroid hormone concentrations are associated with intrap
Autor:
Ibrahim Kulac, Heidi Hempel Sullivan, Nathan Cuka, John R. Barber, Christopher M. Heaphy, Angelo M. De Marzo, Jiayun Lu, Tamara L. Lotan, Corinne E. Joshu, Karen S. Sfanos
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 29:668-675
Background: Given our previous findings that low intratumoral and high extratumoral mast cell numbers are associated with higher risk of biochemical recurrence after radical prostatectomy, we now assessed this relationship with race and the developme
Autor:
Karen S. Sfanos, Javier A. Baena Del Valle, Ibrahim Kulac, Onur Ertunc, Angelo M. De Marzo, Janielle P. Maynard
Publikováno v:
Molecular Cancer Research. 18:153-165
Chronic inflammation and African ancestry are implicated in prostate cancer aggressiveness, and inflammation-related genes are more highly expressed in prostate cancer in African American men. IL8 secretion is also implicated in prostate cancer progr
Autor:
Lionel Chia, Mindy K. Graham, Alan K. Meeker, Michael C. Haffner, Anthony J. Rizzo, Jacqueline A. Brosnan-Cashman, Angelo M. De Marzo, Qizhi Zheng, Javier A. Baena Del Valle, Michael Rubenstein, Michael Considine, Jiyoung Kim, Christine Davis, Leslie Cope, Joseph Da, Christopher M. Heaphy
Publikováno v:
Mol Cancer Res
A key hallmark of cancer, unlimited replication, requires cancer cells to evade both replicative senescence and potentially lethal chromosomal instability induced by telomere dysfunction. The majority of cancers overcome these critical barriers by up