Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Tilman Kühn"'
Publikováno v:
European Journal of Epidemiology
Srour, B, Kaaks, R, Johnson, T, Hynes, L C, Kühn, T & Katzke, V A 2021, ' Ageing-related markers and risks of cancer and cardiovascular disease: a prospective study in the EPIC-Heidelberg cohort ', European Journal of Epidemiology . https://doi.org/10.1007/s10654-021-00828-3
Srour, B, Kaaks, R, Johnson, T, Hynes, L C, Kühn, T & Katzke, V A 2021, ' Ageing-related markers and risks of cancer and cardiovascular disease: a prospective study in the EPIC-Heidelberg cohort ', European Journal of Epidemiology . https://doi.org/10.1007/s10654-021-00828-3
Biological age is an important risk factor for chronic diseases. We examined the associations between five markers of unhealthy ageing; Growth Differentiation Factor-15 (GDF-15), N-terminal pro-brain natriuretic peptide (NT-proBNP), glycated hemoglob
Autor:
Anika Beyer, Paula Schorgg, Nena Karavasiloglou, Sneha Sarwar, Sabine Rohrmann, Till Bärnighausen, Aedin Cassidy, Lisa Connolly, Tilman Kühn
Publikováno v:
Beyer, A, Schorgg, P, Karavasiloglou, N, Sarwar, S, Rohrmann, S, Bärnighausen, T, Cassidy, A, Connolly, L & Kühn, T 2022, ' Urinary phthalate concentrations and mortality risk: A population-based study ', Environmental Research, vol. 214, no. Part 2, 113927 . https://doi.org/10.1016/j.envres.2022.113927
Phthalates are widely used as plasticizers. Laboratory-based mechanistic and epidemiological studies suggest that phthalates are detrimental to human health. Here, we present prospective analyses on phthalate exposure and all-cause, as well as cause-
Publikováno v:
Srour, B, Hynes, L C, Johnson, T, Kühn, T, Katzke, V A & Kaaks, R 2022, ' Serum markers of biological ageing provide long-term prediction of life expectancy: a longitudinal analysis in middle-aged and older German adults ', Age and Ageing, vol. 51, no. 2, afab271 . https://doi.org/10.1093/ageing/afab271
Background lifestyle behaviours and chronic co-morbidities are leading risk factors for premature mortality and collectively predict wide variability in individual life expectancy (LE). We investigated whether a pre-selected panel of five serum marke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94eac36727d71b6409e4f6a0e7ee4c9b
https://pure.qub.ac.uk/en/publications/f605c8d5-7b01-47f4-93ab-ee318345a4b2
https://pure.qub.ac.uk/en/publications/f605c8d5-7b01-47f4-93ab-ee318345a4b2
Autor:
Eva Ardanaz, Agnetha Linn Rostgaard-Hansen, Alessio Naccarati, Elisabete Weiderpass, Pekka Keski-Rahkonen, Rudolf Kaaks, Tilman Kühn, Anna Winkvist, Jośe Mariá Huerta, H. B. Bueno-De-Mesquita, Guri Skeie, Pietro Ferrari, Krasimira Aleksandrova, Gabriel Perlemuter, Augustin Scalbert, Olatz Mokoroa, Giovanna Tagliabue, Marc J. Gunter, Kim Overvad, José Ramón Quirós, Agneta Kiss, Marie-Christine Boutron-Ruault, Yahya Mahamat-Saleh, Talita Duarte-Salles, Nivonirina Robinot, Anne Tjønneland, Antonia Trichopoulou, Julie A. Schmidt, Christina C. Dahm, Roel Vermeulen, Rosario Tumino, Núria Sala, Joseph A. Rothwell, Sophia Harlid, Magdalena Stepien, Klas Sjöberg, Vivian Viallon, Neil Murphy, Anna Karakatsani, Salvatore Panico, Nicholas J. Wareham, María José Sánchez, Francesca Mancini, Domenico Palli, Mazda Jenab, Elio Riboli, Bodil Ohlsson, Kay-Tee Khaw
Publikováno v:
Stepien, M, Keski-Rahkonen, P, Kiss, A, Robinot, N, Duarte-Salles, T, Murphy, N, Perlemuter, G, Viallon, V, Tjønneland, A, Rostgaard-Hansen, A L, Dahm, C C, Overvad, K, Boutron-Ruault, M-C, Mancini, F R, Mahamat-Saleh, Y, Aleksandrova, K, Kaaks, R, Kühn, T, Trichopoulou, A, Karakatsani, A, Panico, S, Tumino, R, Palli, D, Tagliabue, G, Naccarati, A, Vermeulen, R C H, Bueno-de-Mesquita, H B, Weiderpass, E, Skeie, G, Ramón Quirós, J, Ardanaz, E, Mokoroa, O, Sala, N, Sánchez, M-J, Huerta, J M, Winkvist, A, Harlid, S, Ohlsson, B, Sjöberg, K, Schmidt, J A, Wareham, N, Khaw, K-T, Ferrari, P, Rothwell, J A, Gunter, M, Riboli, E, Scalbert, A & Jenab, M 2021, ' Metabolic perturbations prior to hepatocellular carcinoma diagnosis-Findings from a prospective observational cohort study ', International Journal of Cancer, vol. 148, no. 3, pp. 609-625 . https://doi.org/10.1002/ijc.33236
International Journal of Cancer
International Journal of Cancer, Wiley, 2021, 148 (3), pp.609-625. ⟨10.1002/ijc.33236⟩
Stepien, M, Keski-Rahkonen, P, Kiss, A, Robinot, N, Duarte-Salles, T, Murphy, N, Perlemuter, G, Viallon, V, Tjønneland, A, Rostgaard-Hansen, A L, Dahm, C C, Overvad, K, Boutron-Ruault, M-C, Mancini, F R, Mahamat-Saleh, Y, Aleksandrova, K, Kaaks, R, Kühn, T, Trichopoulou, A, Karakatsani, A, Panico, S, Tumino, R, Palli, D, Tagliabue, G, Naccarati, A, Vermeulen, R C H, Bueno-de-Mesquita, H B, Weiderpass, E, Skeie, G, Ramón Quirós, J, Ardanaz, E, Mokoroa, O, Sala, N, Sánchez, M-J, Huerta, J M, Winkvist, A, Harlid, S, Ohlsson, B, Sjöberg, K, Schmidt, J A, Wareham, N, Khaw, K-T, Ferrari, P, Rothwell, J A, Gunter, M, Riboli, E, Scalbert, A & Jenab, M 2021, ' Metabolic perturbations prior to hepatocellular carcinoma diagnosis : Findings from a prospective observational cohort study ', International Journal of Cancer, vol. 148, no. 3, pp. 609-625 . https://doi.org/10.1002/ijc.33236
International Journal of Cancer, 148(3), 609. Wiley-Liss Inc.
International Journal of Cancer
International Journal of Cancer, Wiley, 2021, 148 (3), pp.609-625. ⟨10.1002/ijc.33236⟩
Stepien, M, Keski-Rahkonen, P, Kiss, A, Robinot, N, Duarte-Salles, T, Murphy, N, Perlemuter, G, Viallon, V, Tjønneland, A, Rostgaard-Hansen, A L, Dahm, C C, Overvad, K, Boutron-Ruault, M-C, Mancini, F R, Mahamat-Saleh, Y, Aleksandrova, K, Kaaks, R, Kühn, T, Trichopoulou, A, Karakatsani, A, Panico, S, Tumino, R, Palli, D, Tagliabue, G, Naccarati, A, Vermeulen, R C H, Bueno-de-Mesquita, H B, Weiderpass, E, Skeie, G, Ramón Quirós, J, Ardanaz, E, Mokoroa, O, Sala, N, Sánchez, M-J, Huerta, J M, Winkvist, A, Harlid, S, Ohlsson, B, Sjöberg, K, Schmidt, J A, Wareham, N, Khaw, K-T, Ferrari, P, Rothwell, J A, Gunter, M, Riboli, E, Scalbert, A & Jenab, M 2021, ' Metabolic perturbations prior to hepatocellular carcinoma diagnosis : Findings from a prospective observational cohort study ', International Journal of Cancer, vol. 148, no. 3, pp. 609-625 . https://doi.org/10.1002/ijc.33236
International Journal of Cancer, 148(3), 609. Wiley-Liss Inc.
International audience; Hepatocellular carcinoma (HCC) development entails changes in liver metabolism. Current knowledge on metabolic perturbations in HCC is derived mostly from case-control designs, with sparse information from prospective cohorts.
Autor:
Paula Schorgg, Nena Karavasiloglou, Anika Beyer, Marie Cantwell, Ina Danquah, Jan Gojda, Sabine Rohrmann, Aedin Cassidy, Till Bärnighausen, Monika Cahova, Tilman Kühn
Publikováno v:
Schorgg, P, Karavasiloglou, N, Beyer, A, Cantwell, M, Danquah, I, Gojda, J, Rohrmann, S, Cassidy, A, Bärnighausen, T, Cahova, M & Kühn, T 2022, ' Increased vitamin B6 turnover is associated with greater mortality risk in the general US population: A prospective biomarker study ', Clinical Nutrition, vol. 41, no. 6, pp. 1343-1356 . https://doi.org/10.1016/j.clnu.2022.04.023
BACKGROUND & AIMS: Vitamin B6 status and mortality risk are inversely associated in different patient groups, while prospective studies in the general population are lacking. Here, for the first time, we evaluated the association between biomarkers o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c895d171034906b1dc1fd2404a006029
Autor:
Tilman Kühn, Charlotte Le Cornet, Renée T. Fortner, Theron Johnson, Verena Katzke, Sandra González Maldonado, Araceli Rossello Chornet, Rudolf Kaaks, Konstantin Schildknecht, Sven Olek
Publikováno v:
Cancer Res
Although ample evidence indicates that immune cell homeostasis is an important prognostic outcome determinant in patients with cancer, few studies have examined whether it also determines cancer risk among initially healthy individuals. We performed
Autor:
Pietro Ferrari, Fulvio Ricceri, Christina C. Dahm, Kim Overvad, Sabina Sieri, Elisabete Weiderpass, Eleni Peppa, María José Sánchez, Leila Luján Barroso, Marta Solans Margalef, Matthias B. Schulze, Federico Canzian, Giovanna Masala, Florentin Spaeth, Dagfinn Aune, Roel Vermeulen, Tilman Kühn, Delphine Casabonne, Karin Jirstom, Anna Karakatsani, José María Huerta, Yahya Mahamat-Saleh, Paul Brennan, Cecilie Kyrø, Mats Jerkeman, Caroline Besson, Pilar Amiano Exezarreta, Virginia Menéndez, Elio Riboli, Julie A. Schmidt, Rosario Tumino, Sairah L.F. Chen, Marc J. Gunter, Eva Ardanaz, Antonia Trichopoulou, Alexandra Nieters, Marie-Christine Boutron-Ruault, Anne Tjønneland, Fatemeh Saberi Hosnijeh, Sabine Naudin, Salvatore Panico
Publikováno v:
Naudin, S, Solans Margalef, M, Saberi Hosnijeh, F, Nieters, A, Kyrø, C, Tjønneland, A, Dahm, C C, Overvad, K, Mahamat-Saleh, Y, Besson, C, Boutron-Ruault, M-C, Kühn, T, Canzian, F, Schulze, M B, Peppa, E, Karakatsani, A, Trichopoulou, A, Sieri, S, Masala, G, Panico, S, Tumino, R, Ricceri, F, Chen, S L F, Barroso, L L, Huerta, J M, Sánchez, M-J, Ardanaz, E, Menéndez, V, Amiano Exezarreta, P, Spaeth, F, Jerkeman, M, Jirstom, K, Schmidt, J A, Aune, D, Weiderpass, E, Riboli, E, Vermeulen, R, Casabonne, D, Gunter, M, Brennan, P & Ferrari, P 2020, ' Healthy lifestyle and the risk of lymphoma in the European Prospective Investigation into Cancer and Nutrition study ', International Journal of Cancer, vol. 147, no. 6, pp. 1649-1656 . https://doi.org/10.1002/ijc.32977
International Journal of Cancer
International Journal of Cancer, Wiley, 2020, 147 (6), pp.1649-1656. ⟨10.1002/ijc.32977⟩
Naudin, S, Margalef, M S, Hosnijeh, F S, Nieters, A, Kyrø, C, Tjonneland, A, Dahm, C C, Overvad, K, Mahamat-Saleh, Y, Besson, C, Boutron-Ruault, M-C, Kuehn, T, Canzian, F, Schulze, M B, Peppa, E, Karakatsani, A, Trichopoulou, A, Sieri, S, Masala, G, Panico, S, Tumino, R, Ricceri, F, Chen, S L F, Barroso, L L, Huerta, J M, Sanchez, M-J, Ardanaz, E, Menendez, V, Exezarreta, P A, Spaeth, F, Jerkeman, M, Jirstom, K, Schmidt, J A, Aune, D, Weiderpass, E, Riboli, E, Vermeulen, R, Casabonne, D, Gunter, M, Brennan, P & Ferrari, P 2020, ' Healthy lifestyle and the risk of lymphoma in the European Prospective Investigation into Cancer and Nutrition study ', International Journal of Cancer, vol. 147, no. 6, pp. 1649-1656 . https://doi.org/10.1002/ijc.32977
International Journal of Cancer
International Journal of Cancer, Wiley, 2020, 147 (6), pp.1649-1656. ⟨10.1002/ijc.32977⟩
Naudin, S, Margalef, M S, Hosnijeh, F S, Nieters, A, Kyrø, C, Tjonneland, A, Dahm, C C, Overvad, K, Mahamat-Saleh, Y, Besson, C, Boutron-Ruault, M-C, Kuehn, T, Canzian, F, Schulze, M B, Peppa, E, Karakatsani, A, Trichopoulou, A, Sieri, S, Masala, G, Panico, S, Tumino, R, Ricceri, F, Chen, S L F, Barroso, L L, Huerta, J M, Sanchez, M-J, Ardanaz, E, Menendez, V, Exezarreta, P A, Spaeth, F, Jerkeman, M, Jirstom, K, Schmidt, J A, Aune, D, Weiderpass, E, Riboli, E, Vermeulen, R, Casabonne, D, Gunter, M, Brennan, P & Ferrari, P 2020, ' Healthy lifestyle and the risk of lymphoma in the European Prospective Investigation into Cancer and Nutrition study ', International Journal of Cancer, vol. 147, no. 6, pp. 1649-1656 . https://doi.org/10.1002/ijc.32977
This is the peer reviewed version of the following article: Naudin, S., Margalef, M.S., Hosnijeh, F.S., Nieters, A., Kyrø, C. Tjønneland, A. ... Ferrari, P. (2020) Healthy lifestyle and the risk of lymphoma in the European Prospective Investigation
Autor:
Ezgi Eyluel Bankoglu, Trasias Mukama, Verena Katzke, Franzisca Stipp, Theron Johnson, Tilman Kühn, Florian Seyfried, Roger Godschalk, Andrew Collins, Rudolf Kaaks, Helga Stopper
Publikováno v:
Bankoglu, E E, Mukama, T, Katzke, V, Stipp, F, Johnson, T, Kühn, T, Seyfried, F, Godschalk, R, Collins, A, Kaaks, R & Stopper, H 2022, ' Short-and long-term reproducibility of the COMET assay for measuring DNA damage biomarkers in frozen blood samples of the EPIC-Heidelberg cohort ', Mutation Research/Genetic Toxicology and Environmental Mutagenesis, vol. 874-875, 503442 . https://doi.org/10.1016/j.mrgentox.2022.503442
Mutation Research-Genetic Toxicology and Environmental Mutagenesis, 874-875:503442. Elsevier
Mutation Research-Genetic Toxicology and Environmental Mutagenesis, 874-875:503442. Elsevier
The comet assay is widely used for quantification of genomic damage in humans. Peripheral blood derived mononuclear cells (PBMCs) are the most often used cell type for this purpose. Since the comet assay can be performed in an enhanced throughput for
Autor:
Joseph A. Rothwell, Mojgan Karimi, S. Ghazaleh Dashti, Neil Murphy, Mazda Jenab, Thérèse Truong, Yahya Mahamat-Saleh, Marc J. Gunter, Gianluca Severi, Tilman Kühn, Amanda J. Cross, Pietro Ferrari
Publikováno v:
Rothwell, J A, Jenab, M, Karimi, M, Truong, T, Mahamat-Saleh, Y, Ferrari, P, Dashti, S G, Kühn, T, Cross, A J, Severi, G, Gunter, M J & Murphy, N 2022, ' Metabolic Syndrome and Risk of Gastrointestinal Cancers: An Investigation Using Large-scale Molecular Data ', Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, vol. 20, no. 6, pp. e1338-e1352 . https://doi.org/10.1016/j.cgh.2021.10.016
Clinical Gastroenterology and Hepatology
Clinical Gastroenterology and Hepatology, WB Saunders, 2022, 20 (6), pp.e1338-e1352. ⟨10.1016/j.cgh.2021.10.016⟩
Clinical Gastroenterology and Hepatology
Clinical Gastroenterology and Hepatology, WB Saunders, 2022, 20 (6), pp.e1338-e1352. ⟨10.1016/j.cgh.2021.10.016⟩
International audience; Background & Aims: Gastrointestinal cancer risk is influenced by the presence of metabolic syndrome (MetS). However, previous epidemiologic studies lacked full serological biomarker data for the classification of MetS, and the
Autor:
Fulvio Ricceri, Joseph A. Rothwell, Amanda J. Cross, Graham G. Giles, Elisabete Weiderpass, Tilman Kühn, Emily Sonestedt, Yi Yang, Rudolf Kaaks, Valeria Pala, Anna Karakatsani, Dallas R. English, Rosario Tumino, Pilar Amiano, Antonia Trichopoulou, John L. Hopper, Leila Lujan-Barroso, Allison M. Hodge, Bengt Wallner, Ruth C. Travis, María Dolores López, Anne Tjønneland, Hazel M. Mitchell, Kostas Tsilidis, Domenico Palli, Harindra Jayasekara, Elio Riboli, Antonio Agudo, Robin Room, Heiner Boeing, Eva Ardanaz, Bas Bueno-de-Mesquita, Torkjel M. Sandanger, Pietro Ferrari, Robert J. MacInnis, Susana Merino, Andrew Haydon, Eleni Peppa, Marie-Christine Boutron-Ruault, Salvatore Panico, María José Sánchez, Marc J. Gunter, Hanna Sternby, Roger L. Milne, Gianluca Severi, Ana Lucia Mayen-Chacon
Publikováno v:
International Journal of Cancer
International Journal of Cancer, Wiley, 2021, 148 (11), pp.2759-2773. ⟨10.1002/ijc.33504⟩
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Dipòsit Digital de la UB
Universidad de Barcelona
Jayasekara, H, MacInnis, R J, Lujan-Barroso, L, Mayen-Chacon, A-L, Cross, A J, Wallner, B, Palli, D, Ricceri, F, Pala, V, Panico, S, Tumino, R, Kuehn, T, Kaaks, R, Tsilidis, K, Sanchez, M-J, Amiano, P, Ardanaz, E, Chirlaque Lopez, M D, Merino, S, Rothwell, J A, Boutron-Ruault, M-C, Severi, G, Sternby, H, Sonestedt, E, Bueno-de-Mesquita, B, Boeing, H, Travis, R, Sandanger, T M, Trichopoulou, A, Karakatsani, A, Peppa, E, Tjonneland, A, Yang, Y, Hodge, A M, Mitchell, H, Haydon, A, Room, R, Hopper, J L, Weiderpass, E, Gunter, M J, Riboli, E, Giles, G G, Milne, R L, Agudo, A, English, D R & Ferrari, P 2021, ' Lifetime alcohol intake, drinking patterns over time and risk of stomach cancer : A pooled analysis of data from two prospective cohort studies ', International Journal of Cancer, vol. 148, no. 11, pp. 2759-2773 . https://doi.org/10.1002/ijc.33504
Digibug. Repositorio Institucional de la Universidad de Granada
instname
International Journal of Cancer, Wiley, 2021, 148 (11), pp.2759-2773. ⟨10.1002/ijc.33504⟩
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Dipòsit Digital de la UB
Universidad de Barcelona
Jayasekara, H, MacInnis, R J, Lujan-Barroso, L, Mayen-Chacon, A-L, Cross, A J, Wallner, B, Palli, D, Ricceri, F, Pala, V, Panico, S, Tumino, R, Kuehn, T, Kaaks, R, Tsilidis, K, Sanchez, M-J, Amiano, P, Ardanaz, E, Chirlaque Lopez, M D, Merino, S, Rothwell, J A, Boutron-Ruault, M-C, Severi, G, Sternby, H, Sonestedt, E, Bueno-de-Mesquita, B, Boeing, H, Travis, R, Sandanger, T M, Trichopoulou, A, Karakatsani, A, Peppa, E, Tjonneland, A, Yang, Y, Hodge, A M, Mitchell, H, Haydon, A, Room, R, Hopper, J L, Weiderpass, E, Gunter, M J, Riboli, E, Giles, G G, Milne, R L, Agudo, A, English, D R & Ferrari, P 2021, ' Lifetime alcohol intake, drinking patterns over time and risk of stomach cancer : A pooled analysis of data from two prospective cohort studies ', International Journal of Cancer, vol. 148, no. 11, pp. 2759-2773 . https://doi.org/10.1002/ijc.33504
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Alcohol consumption is causally linked to several cancers but the evidence for stomach cancer is inconclusive. In our study, the association between long-term alcohol intake and risk of stomach cancer and its subtypes was evaluated. We performed a po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a30639f9ec2127afddd3ec749301eb3b
https://hal.archives-ouvertes.fr/hal-03287365
https://hal.archives-ouvertes.fr/hal-03287365