Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Xiaohan Lu"'
Autor:
Xiyang Liu, Chuanming Xu, Sunhapas Soodvilai, Xiaohan Lu, Fei Wang, Kexin Peng, Tianxin Yang, Renfei Luo
Publikováno v:
Am J Physiol Renal Physiol
We have previously shown that activation of (pro)renin receptor (PRR) induces epithelial Na+channel (ENaC) activity in cultured collecting duct cells. Here, we examined the role of soluble PRR (sPRR), the cleavage product of PRR in ENaC regulation, a
Autor:
Jiahui Su, Jae Min Cho, Xiaohan Lu, Fei Wang, Chang-Jiang Zou, Aihua Lu, Jiajia Hu, Tianxin Yang, Xiyang Liu, Ziwei Fu, J. David Symons
Publikováno v:
Clinical science (London, England : 1979). 135(6)
Until now, renin–angiotensin system (RAS) hyperactivity was largely thought to result from angiotensin II (Ang II)-dependent stimulation of the Ang II type 1 receptor (AT1R). Here we assessed the role of soluble (pro)renin receptor (sPRR), a produc
Publikováno v:
American Journal of Physiology-Renal Physiology. 312:F245-F253
The (pro)renin receptor (PRR) is abundantly expressed in the collecting duct (CD) and the expression is further induced by angiotensin II (ANG II). The present study was conducted to investigate the role of CD PRR during ANG II-induced hypertension a
Autor:
Shu-Feng Zhou, Adam Nau, Hui Fang, Atsuhiro Ichihara, Jiahui Su, Li Zhou, Aihua Lu, Kexin Peng, Fei Wang, Xiaohan Lu, Tianxin Yang, Kevin T. Yang
Publikováno v:
Journal of the American Society of Nephrology. 27:3022-3034
Within the kidney, the (pro)renin receptor (PRR) is predominantly expressed in the collecting duct (CD), particularly in intercalated cells, and it is regulated by the PGE2 receptor EP4 Notably, EP4 also controls urinary concentration through regulat
Autor:
Ziwei Fu, Fei Wang, Xiyang Liu, Jiajia Hu, Jiahui Su, Xiaohan Lu, Aihua Lu, Jae Min Cho, Symons, J. David, Chang-Jiang Zou, Tianxin Yang
Publikováno v:
Clinical Science; Mar2021, Vol. 135 Issue 6, p793-810, 18p
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 69(2)
A high-fructose diet is shown to induce salt-sensitive hypertension, but the underlying mechanism largely remains unknown. The major goal of the present study was to test the role of renal (pro)renin receptor (PRR) in this model. In Sprague–Dawley
Autor:
Long Zhao, Jiahui Su, Shu-Feng Zhou, Sunny Soodvilai, Kevin T. Yang, Chuanming Xu, Kexin Peng, Fei Wang, Xiaohan Lu, Jan-Åke Gustafsson, Tianxin Yang, Yumei Feng
The extracellular domain of the (pro)renin receptor (PRR) is cleaved to produce a soluble (pro)renin receptor (sPRR) that is detected in biological fluid and elevated under certain pathological conditions. The present study was performed to define th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2330122b0514dbd30fb3ed4c058baef5
https://europepmc.org/articles/PMC4822598/
https://europepmc.org/articles/PMC4822598/
Autor:
Van Reese, Kevin T. Yang, Donald E. Kohan, Xiaohan Lu, Russell S. Richardson, Mi Liu, Fei Wang, Adam Nau, Tianxin Yang
Publikováno v:
American journal of physiology. Renal physiology. 310(11)
The collecting duct (CD) has been recognized as an important source of prorenin/renin, and it also expresses (pro)renin receptor (PRR). The goal of this study was to examine the hypothesis that prorenin or renin via PRR regulates epithelial Na+channe
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 64(2)
Angiotensin II (Ang II) stimulates (pro)renin receptor (PRR) expression in the renal collecting duct, triggering the local renin response in the distal nephron. Our recent study provided evidence for involvement of cyclooxygenase-2–prostaglandin E
Autor:
Xiaohan Lu, Fei Wang, Mi Liu, Yang, Kevin T., Adam Nau, Kohan, Donald E., Van Reese, Richardson, Russell S., Tianxin Yang
Publikováno v:
American Journal of Physiology: Renal Physiology; Jun2016, Vol. 310 Issue 11, pF1243-F1250, 8p