Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Yong J. Lee"'
Autor:
Xu Luo, Yong Seok Park, Kalishwaralal Kalimuthu, M. Haroon A. Choudry, David L. Bartlett, Young Sun Lee, Yong J. Lee
Publikováno v:
Apoptosis
Ferroptosis is considered a distinctive form of cell death compared to other types of death such as apoptosis. It is known to result from iron-dependent accumulation of lipid peroxides rather than caspase activation. However, we reported recently tha
Publikováno v:
Orphanet Journal of Rare Diseases
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-13 (2020)
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-13 (2020)
Background Mucinous colon cancers (MCC) are characterized by abundant production of mucin 2 (MUC2) protein and are less sensitive to standard systemic chemotherapy. We postulated that severe/persistent endoplasmic reticulum stress (ERS) aggravation i
Autor:
Xinxin Song, Haroon A. Choudry, Yong J. Lee, Yong Tae Kwon, Young Sun Lee, David L. Bartlett, Ashok K. Dilly, Dae Hee Lee
Publikováno v:
Molecular Cancer Research. 16:1077-1091
Emerging evidence demonstrates that autophagy and apoptosis are interconnected and their interplay greatly affects cell death. However, the key regulators in this crosstalk remain elusive. Therefore, the role of N-terminal arginylated BiP (R-BiP)/Bec
Autor:
Hima Makala, Kalishwaralal Kalimuthu, Young Sun Lee, Yong Seok Park, Yong J. Lee, Simon C. Watkins, Yong Tae Kwon, M. Haroon A. Choudry, David L. Bartlett
Publikováno v:
J Cell Physiol
Ferroptosis has been reported as a unique form of cell death. However, in recent years, researchers have increasingly challenged the uniqueness of ferroptosis compared to other types of cell death. In this study, we examined whether ferroptosis share
Autor:
Young Sun Lee, Yong J. Lee
Publikováno v:
Ferroptosis in Health and Disease ISBN: 9783030267797
Since its discovery in 2012, ferroptosis has been well characterized as an iron-dependent regulated form of cell death caused by the accumulation of lipid-based reactive oxygen species. The endoplasmic reticulum (ER) stress response is one of the int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17d4d1db8de9c5be0bb6d1661b5ef573
https://doi.org/10.1007/978-3-030-26780-3_5
https://doi.org/10.1007/978-3-030-26780-3_5
Autor:
Yong J. Lee
Publikováno v:
Cancer Research. 80:1239-1239
Ferroptosis has been reported as a unique form of cell death. However, in recent years, researchers have increasingly challenged the uniqueness of ferroptosis compared to other types of cell death. In this study, we examined whether ferroptosis share
Ferroptosis-inducing agents enhance TRAIL-induced apoptosis through upregulation of death receptor 5
Autor:
Dae Hee Lee, Jian Yu, David L. Bartlett, Yong Seok Park, Haroon A. Choudry, Yong J. Lee, Seong Hye Park, So Yeon Jeong, Young Sun Lee, Sang Cheul Oh
Publikováno v:
Journal of cellular biochemistry. 120(1)
Ferroptosis is considered genetically and biochemically distinct from other forms of cell death. In this study, we examined whether ferroptosis shares cell death pathways with other types of cell death. When human colon cancer HCT116, CX-1, and LS174
Publikováno v:
Molecular cancer research : MCR. 16(7)
Since its discovery in 2012, ferroptosis has been well characterized by the accumulation of lipid peroxides due to the failure of glutathione-dependent antioxidant defenses. It is known as an iron-dependent form of programmed cell death, which is dis
Autor:
Yong J. Lee, Dae Hee Lee, Haroon A. Choudry, Min Jee Jo, David L. Bartlett, Young Sun Lee, William T. Kwon, Yoon A. Jeong, Se Hoon Hong
Publikováno v:
Oncotarget
Ferroptosis is a type of programmed cell death that depends on iron and is characterized by the accumulation of lipid peroxides. In the present study, we investigated the nature of the interplay between ferroptosis and other forms of cell death such
Autor:
Yong J. Lee
Publikováno v:
Cancer Research. 79:707-707
Introduction: Several processes lead to cell death; ferroptosis, apoptosis, necrosis, and autophagy are the primary mechanisms. Each type of biological death has been believed to have a distinct biochemical and morphological fingerprint. However, eme