Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Gil Atzmon"'
Autor:
George Hindy, Peter Dornbos, Mark D. Chaffin, Dajiang J. Liu, Minxian Wang, Margaret Sunitha Selvaraj, David Zhang, Joseph Park, Carlos A. Aguilar-Salinas, Lucinda Antonacci-Fulton, Diego Ardissino, Donna K. Arnett, Stella Aslibekyan, Gil Atzmon, Christie M. Ballantyne, Francisco Barajas-Olmos, Nir Barzilai, Lewis C. Becker, Lawrence F. Bielak, Joshua C. Bis, John Blangero, Eric Boerwinkle, Lori L. Bonnycastle, Erwin Bottinger, Donald W. Bowden, Matthew J. Bown, Jennifer A. Brody, Jai G. Broome, Noël P. Burtt, Brian E. Cade, Federico Centeno-Cruz, Edmund Chan, Yi-Cheng Chang, Yii-Der I. Chen, Ching-Yu Cheng, Won Jung Choi, Rajiv Chowdhury, Cecilia Contreras-Cubas, Emilio J. Córdova, Adolfo Correa, L. Adrienne Cupples, Joanne E. Curran, John Danesh, Paul S. de Vries, Ralph A. DeFronzo, Harsha Doddapaneni, Ravindranath Duggirala, Susan K. Dutcher, Patrick T. Ellinor, Leslie S. Emery, Jose C. Florez, Myriam Fornage, Barry I. Freedman, Valentin Fuster, Ma. Eugenia Garay-Sevilla, Humberto García-Ortiz, Soren Germer, Richard A. Gibbs, Christian Gieger, Benjamin Glaser, Clicerio Gonzalez, Maria Elena Gonzalez-Villalpando, Mariaelisa Graff, Sarah E. Graham, Niels Grarup, Leif C. Groop, Xiuqing Guo, Namrata Gupta, Sohee Han, Craig L. Hanis, Torben Hansen, Jiang He, Nancy L. Heard-Costa, Yi-Jen Hung, Mi Yeong Hwang, Marguerite R. Irvin, Sergio Islas-Andrade, Gail P. Jarvik, Hyun Min Kang, Sharon L.R. Kardia, Tanika Kelly, Eimear E. Kenny, Alyna T. Khan, Bong-Jo Kim, Ryan W. Kim, Young Jin Kim, Heikki A. Koistinen, Charles Kooperberg, Johanna Kuusisto, Soo Heon Kwak, Markku Laakso, Leslie A. Lange, Jiwon Lee, Juyoung Lee, Seonwook Lee, Donna M. Lehman, Rozenn N. Lemaitre, Allan Linneberg, Jianjun Liu, Ruth J.F. Loos, Steven A. Lubitz, Valeriya Lyssenko, Ronald C.W. Ma, Lisa Warsinger Martin, Angélica Martínez-Hernández, Rasika A. Mathias, Stephen T. McGarvey, Ruth McPherson, James B. Meigs, Thomas Meitinger, Olle Melander, Elvia Mendoza-Caamal, Ginger A. Metcalf, Xuenan Mi, Karen L. Mohlke, May E. Montasser, Jee-Young Moon, Hortensia Moreno-Macías, Alanna C. Morrison, Donna M. Muzny, Sarah C. Nelson, Peter M. Nilsson, Jeffrey R. O’Connell, Marju Orho-Melander, Lorena Orozco, Colin N.A. Palmer, Nicholette D. Palmer, Cheol Joo Park, Kyong Soo Park, Oluf Pedersen, Juan M. Peralta, Patricia A. Peyser, Wendy S. Post, Michael Preuss, Bruce M. Psaty, Qibin Qi, D.C. Rao, Susan Redline, Alexander P. Reiner, Cristina Revilla-Monsalve, Stephen S. Rich, Nilesh Samani, Heribert Schunkert, Claudia Schurmann, Daekwan Seo, Jeong-Sun Seo, Xueling Sim, Rob Sladek, Kerrin S. Small, Wing Yee So, Adrienne M. Stilp, E. Shyong Tai, Claudia H.T. Tam, Kent D. Taylor, Yik Ying Teo, Farook Thameem, Brian Tomlinson, Michael Y. Tsai, Tiinamaija Tuomi, Jaakko Tuomilehto, Teresa Tusié-Luna, Miriam S. Udler, Rob M. van Dam, Ramachandran S. Vasan, Karine A. Viaud Martinez, Fei Fei Wang, Xuzhi Wang, Hugh Watkins, Daniel E. Weeks, James G. Wilson, Daniel R. Witte, Tien-Yin Wong, Lisa R. Yanek, Sekar Kathiresan, Daniel J. Rader, Jerome I. Rotter, Michael Boehnke, Mark I. McCarthy, Cristen J. Willer, Pradeep Natarajan, Jason A. Flannick, Amit V. Khera, Gina M. Peloso
Publikováno v:
Hindy, G, Dornbos, P, Chaffin, M D, Liu, D J, Wang, M, Selvaraj, M S, Zhang, D, Park, J, Aguilar-Salinas, C A, Antonacci-Fulton, L, Ardissino, D, Arnett, D K, Aslibekyan, S, Atzmon, G, Ballantyne, C M, Barajas-Olmos, F, Barzilai, N, Becker, L C, Bielak, L F, Bis, J C, Blangero, J, Boerwinkle, E, Bonnycastle, L L, Bottinger, E, Bowden, D W, Bown, M J, Brody, J A, Broome, J G, Burtt, N P, Cade, B E, Centeno-Cruz, F, Chan, E, Chang, Y C, Chen, Y D I, Cheng, C Y, Choi, W J, Chowdhury, R, Contreras-Cubas, C, Córdova, E J, Correa, A, Cupples, L A, Curran, J E, Danesh, J, de Vries, P S, Grarup, N, Hansen, T, Linneberg, A, Loos, R J F, Pedersen, O, Witte, D R, AMP-T2D-GENES, Myocardial Infarction Genetics Consortium, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium & NHLBI TOPMed Lipids Working Group 2022, ' Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes ', American Journal of Human Genetics, vol. 109, no. 1, pp. 81-96 . https://doi.org/10.1016/j.ajhg.2021.11.021
Am J Hum Genet
Hindy, G, Dornbos, P, Chaffin, M D, Liu, D J, Wang, M, Selvaraj, M S, Zhang, D, Park, J, Aguilar-Salinas, C A, Antonacci-Fulton, L, Ardissino, D, Arnett, D K, Aslibekyan, S, Atzmon, G, Ballantyne, C M, Barajas-Olmos, F, Barzilai, N, Becker, L C, Bielak, L F, Bis, J C, Blangero, J, Boerwinkle, E, Bonnycastle, L L, Bottinger, E, Bowden, D W, Bown, M J, Brody, J A, Broome, J G, Burtt, N P, Cade, B E, Centeno-Cruz, F, Chan, E, Chang, Y C, Chen, Y D I, Cheng, C Y, Choi, W J, Chowdhury, R, Contreras-Cubas, C, Córdova, E J, Correa, A, Cupples, L A, Curran, J E, Danesh, J, de Vries, P S, DeFronzo, R A, Grarup, N, Hansen, T, Pedersen, O, Wang, F F, Witte, D R, AMP-T2D-GENES, Myocardial Infarction Genetics Consortium, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium & NHLBI TOPMed Lipids Working Group 2022, ' Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes ', American Journal of Human Genetics, vol. 109, no. 1, pp. 81-96 . https://doi.org/10.1016/j.ajhg.2021.11.021
Hindy, G, Dornbos, P, Chaffin, M D, Liu, D J, Wang, M, Selvaraj, M S, Zhang, D, Park, J, Aguilar-Salinas, C A, Antonacci-Fulton, L, Ardissino, D, Arnett, D K, Aslibekyan, S, Atzmon, G, Ballantyne, C M, Barajas-Olmos, F, Barzilai, N, Becker, L C, Bielak, L F, Bis, J C, Blangero, J, Boerwinkle, E, Bonnycastle, L L, Bottinger, E, Bowden, D W, Bown, M J, Brody, J A, Broome, J G, Burtt, N P, Cade, B E, Centeno-Cruz, F, Chan, E, Chang, Y-C, Chen, Y-D I, Cheng, C-Y, Choi, W J, Chowdhury, R, Contreras-Cubas, C, Córdova, E J, Correa, A, Cupples, L A, Curran, J E, Danesh, J, de Vries, P S, DeFronzo, R A, Doddapaneni, H, Duggirala, R, Dutcher, S K, Ellinor, P T, Grarup, N, Hansen, T, Pedersen, O, Linneberg, A, Witte, D R & AMP-T2D-GENES, Myocardial Infarction Genetics Consortium 2022, ' Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes ', American Journal of Human Genetics, vol. 109, no. 1, pp. 81-96 . https://doi.org/10.1016/j.ajhg.2021.11.021
Am J Hum Genet
Hindy, G, Dornbos, P, Chaffin, M D, Liu, D J, Wang, M, Selvaraj, M S, Zhang, D, Park, J, Aguilar-Salinas, C A, Antonacci-Fulton, L, Ardissino, D, Arnett, D K, Aslibekyan, S, Atzmon, G, Ballantyne, C M, Barajas-Olmos, F, Barzilai, N, Becker, L C, Bielak, L F, Bis, J C, Blangero, J, Boerwinkle, E, Bonnycastle, L L, Bottinger, E, Bowden, D W, Bown, M J, Brody, J A, Broome, J G, Burtt, N P, Cade, B E, Centeno-Cruz, F, Chan, E, Chang, Y C, Chen, Y D I, Cheng, C Y, Choi, W J, Chowdhury, R, Contreras-Cubas, C, Córdova, E J, Correa, A, Cupples, L A, Curran, J E, Danesh, J, de Vries, P S, DeFronzo, R A, Grarup, N, Hansen, T, Pedersen, O, Wang, F F, Witte, D R, AMP-T2D-GENES, Myocardial Infarction Genetics Consortium, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium & NHLBI TOPMed Lipids Working Group 2022, ' Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes ', American Journal of Human Genetics, vol. 109, no. 1, pp. 81-96 . https://doi.org/10.1016/j.ajhg.2021.11.021
Hindy, G, Dornbos, P, Chaffin, M D, Liu, D J, Wang, M, Selvaraj, M S, Zhang, D, Park, J, Aguilar-Salinas, C A, Antonacci-Fulton, L, Ardissino, D, Arnett, D K, Aslibekyan, S, Atzmon, G, Ballantyne, C M, Barajas-Olmos, F, Barzilai, N, Becker, L C, Bielak, L F, Bis, J C, Blangero, J, Boerwinkle, E, Bonnycastle, L L, Bottinger, E, Bowden, D W, Bown, M J, Brody, J A, Broome, J G, Burtt, N P, Cade, B E, Centeno-Cruz, F, Chan, E, Chang, Y-C, Chen, Y-D I, Cheng, C-Y, Choi, W J, Chowdhury, R, Contreras-Cubas, C, Córdova, E J, Correa, A, Cupples, L A, Curran, J E, Danesh, J, de Vries, P S, DeFronzo, R A, Doddapaneni, H, Duggirala, R, Dutcher, S K, Ellinor, P T, Grarup, N, Hansen, T, Pedersen, O, Linneberg, A, Witte, D R & AMP-T2D-GENES, Myocardial Infarction Genetics Consortium 2022, ' Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes ', American Journal of Human Genetics, vol. 109, no. 1, pp. 81-96 . https://doi.org/10.1016/j.ajhg.2021.11.021
Large-scale gene sequencing studies for complex traits have the potential to identify causal genes with therapeutic implications. We performed gene-based association testing of blood lipid levels with rare (minor allele frequency < 1%) predicted dama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d53d518c5a9781ccf6a21517fa2887b9
https://hdl.handle.net/20.500.12105/15626
https://hdl.handle.net/20.500.12105/15626
Autor:
Ryan J. Longchamps, Rozenn N. Lemaitre, Traci M. Bartz, Henning Tiemeier, Anna L. Guyatt, Nir Barzilai, A.G. Uitterlinden, A. C. Y. Mak, C M van Duijn, Eric Boerwinkle, Mary F. Feitosa, Stephen S. Rich, Rui Xia, Gil Atzmon, Santiago Rodriguez, Bruce M. Psaty, Dan E. Arking, Chloé Sarnowski, Jerome I. Rotter, Mark O. Goodarzi, Megan L. Grove, Jennifer A. Brody, Joanne M. Murabito, J.B. van Meurs, Mary K. Wojczynski, K. Ye, Aviv Bergman, Nona Sotoodehnia, Tom R. Gaunt, Le Yu, Nathan Pankratz, Myriam Fornage, Najaf Amin, Tim Kacprowski, Kathryn L. Lunetta, Ching-Ti Liu, Jingyun Yang, Kent D. Taylor, Fernando Rivadeneira, David A. Bennett, Kimberley Burrows, S. Y. Yang, Michael A. Province, Wei Shi, C. M. Sitlani, Laura M. Raffield, P. L. De Jager, Leslie A. Lange, Aldi T. Kraja, Linda Broer, John Lane, Christina A. Castellani
Publikováno v:
Longchamps, R J, Yang, S Y, Castellani, C A, Shi, W, Lane, J, Grove, M L, Bartz, T M, Sarnowski, C, Liu, C, Burrows, K, Guyatt, A L, Gaunt, T R, Kacprowski, T, Yang, J, De Jager, P L, Yu, L, Bergman, A, Xia, R, Fornage, M, Feitosa, M F, Wojczynski, M K, Kraja, A T, Province, M A, Amin, N, Rivadeneira, F, Tiemeier, H, Uitterlinden, A G, Broer, L, Van Meurs, J B J, Van Duijn, C M, Raffield, L M, Lange, L, Rich, S S, Lemaitre, R N, Goodarzi, M O, Sitlani, C M, Mak, A C Y, Bennett, D A, Rodriguez, S, Murabito, J M, Lunetta, K L, Sotoodehnia, N, Atzmon, G, Ye, K, Barzilai, N, Brody, J A, Psaty, B M, Taylor, K D, Rotter, J I, Boerwinkle, E, Pankratz, N & Arking, D E 2022, ' Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation ', Human Genetics, vol. 141, no. 1, pp. 127-146 . https://doi.org/10.1007/s00439-021-02394-w
Paediatrics Publications
Human genetics, vol 141, iss 1
Human Genetics, 141(1), 127-146. Springer-Verlag
Human Genetics
Paediatrics Publications
Human genetics, vol 141, iss 1
Human Genetics, 141(1), 127-146. Springer-Verlag
Human Genetics
Mitochondrial DNA copy number (mtDNA-CN) measured from blood specimens is a minimally invasive marker of mitochondrial function that exhibits both inter-individual and intercellular variation. To identify genes involved in regulating mitochondrial fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::271655c774846c1bff335569b9acbe6b
https://hdl.handle.net/1983/88fc5165-58e5-4d81-a3d0-6c2dc336580a
https://hdl.handle.net/1983/88fc5165-58e5-4d81-a3d0-6c2dc336580a
Autor:
Nir Barzilai, Peter Davies, Robert P. Adelson, Alan E. Renton, Alison Goate, Yun Freudenberg-Hua, Gil Atzmon, Wentian Li
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
The success of next-generation sequencing depends on the accuracy of variant calls. Few objective protocols exist for QC following variant calling from whole genome sequencing (WGS) data. After applying QC filtering based on Genome Analysis Tool Kit
Autor:
Francesco Villa, Anastasia Gurinovich, Gil Atzmon, Annibale Alessandro Puca, Thomas T. Perls, Harold Bae, Aldi T. Kraja, Stacy L. Andersen, Paola Sebastiani, Nir Barzilai, Danny Ben-Avraham, Alberto Malovini
Publikováno v:
The Journals of Gerontology: Series A. 72:1453-1464
The search for the genetic determinants of extreme human longevity has been challenged by the phenotype's rarity and its nonspecific definition by investigators. To address these issues, we established a consortium of four studies of extreme longevit
Autor:
John D. Eicher, Dena G. Hernandez, Maria Nethander, Russell Thomson, Thomas H. Mosley, Amy M. Matteini, Lenore J. Launer, Gil Atzmon, A.B. Newman, Dan Mellström, Lital Sharvit, Stephen T. Turner, Joe Verghese, Simon P. Mooijaart, Douglas P. Kiel, Jessica D. Faul, Stefania Bandinelli, Jeremy D. Walston, D. S. Knopman, John M. Starr, David R. Weir, Wei Zhao, Jennifer A. Smith, Sharon L.R. Kardia, Ian J. Deary, Beverly G Windham, Joris Deelen, Alice M. Arnold, Denis A. Evans, Eline Slagboom, Gail Davies, Danielle Gutman, Rotem Vered, David C. Liewald, Magnus Karlsson, Alison Pattie, Kathryn L. Lunetta, Velandai Srikanth, Vilmundur Gudnason, Janie Corley, Joanne M. Murabito, Luigi Ferrucci, Vincent J. A. Verlinden, Michele L. Callisaya, Tamara B. Harris, Danny Ben-Avraham, Jos N. van der Geest, Lei Yu, David Karasik, Philip L. De Jager, Gregory J. Tranah, Toshiko Tanaka, Jeanine J. Houwing-Duistermaat, Aron S. Buchman, Hieab H.H. Adams, Myriam Fornage, Albert V. Smith, Matthijs Moed, Claes Ohlsson, Andrew D. Johnson, Marian Beekman, André G. Uitterlinden, Neeta Parimi, M. Arfan Ikram, Steven R. Cummings, Albert Hofman, Rebekah McWhirter, Yongmei Liu, Daniel S. Evans, David A. Bennett
Publikováno v:
Aging (Albany NY)
Emerging evidence suggests that the basis for variation in late-life mobility is attributable, in part, to genetic factors, which may become increasingly important with age. Our objective was to systematically assess the contribution of genetic varia
Autor:
Gil Atzmon, Stacy L. Andersen, Annibale Alessandro Puca, Anastasia Gurinovich, Alberto Malovini, Thomas T. Perls, Francesco Villa, Harold Bae, Nir Barzilai, Paola Sebastiani
Previous studies note specific FOXO3 single-nucleotide polymorphisms (SNPs) associated with human longevity. However, it is not clear if these SNPs influence mortality risk beyond the oldest 1 percentile of survival. Using data from four longevity st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b6983bea224e2753e61c076554870d4
https://europepmc.org/articles/PMC6175020/
https://europepmc.org/articles/PMC6175020/
Autor:
Vladimir Vacic, Mali Gana-Weisz, Eimear E. Kenny, Aviv Bergman, Ariel Darvasi, Nir Giladi, Avi Orr-Urtreger, Inga Peter, Harry Ostrer, Hakon Hakonarson, Alexander Gusev, Todd Lencz, Lorraine N. Clark, Laurie J. Ozelius, Deborah Raymond, Merav Kedmi, Susan B. Bressman, Anat Bar-Shira, Rachel Saunders-Pullman, Helen Mejia-Santana, Anat Mirelman, Tanya Gurevich, Nir Barzilai, Edward R. Burns, Saurav Guha, Karen Marder, Xinmin Liu, Robert J. Desnick, Gil Atzmon, Itsik Pe'er
Publikováno v:
Human Molecular Genetics. 23:4693-4702
The recent series of large genome-wide association studies in European and Japanese cohorts established that Parkinson disease (PD) has a substantial genetic component. To further investigate the genetic landscape of PD, we performed a genome-wide sc
Autor:
Gil Atzmon, Howard Y. Chang, Anne Lynn S. Chang, Aviv Bergman, Samantha A. Brugmann, Nir Barzilai, Scott X. Atwood
Publikováno v:
Chang, ALS; Atzmon, G; Bergman, A; Brugmann, S; Atwood, SX; Chang, HY; et al.(2014). Identification of genes promoting skin youthfulness by genome-wide association study. Journal of Investigative Dermatology, 134(3), 651-657. doi: 10.1038/jid.2013.381. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/9mc0v4gh
The Journal of investigative dermatology, vol 134, iss 3
The Journal of Investigative Dermatology
The Journal of investigative dermatology, vol 134, iss 3
The Journal of Investigative Dermatology
To identify genes that promote facial skin youthfulness (SY), a genome-wide association study on an Ashkenazi Jewish discovery group (n=428) was performed using Affymetrix 6.0 Single-Nucleotide Polymorphism (SNP) Array. After SNP quality controls, 90
Autor:
Manuel A Rivas, Brandon E Avila, Jukka Koskela, Hailiang Huang, Christine Stevens, Matti Pirinen, Talin Haritunians, Benjamin M Neale, Mitja Kurki, Andrea Ganna, Daniel Graham, Benjamin Glaser, Inga Peter, Gil Atzmon, Nir Barzilai, Adam P Levine, Elena Schiff, Nikolas Pontikos, Ben Weisburd, Monkol Lek, Konrad J Karczewski, Jonathan Bloom, Eric V Minikel, Britt-Sabina Petersen, Laurent Beaugerie, Philippe Seksik, Jacques Cosnes, Stefan Schreiber, Bernd Bokemeyer, Johannes Bethge, International IBD Genetics Consortium, NIDDK IBD Genetics Consortium, T2D-GENES Consortium, Graham Heap, Tariq Ahmad, Vincent Plagnol, Anthony W Segal, Stephan Targan, Dan Turner, Paivi Saavalainen, Martti Farkkila, Kimmo Kontula, Aarno Palotie, Steven R Brant, Richard H Duerr, Mark S Silverberg, John D Rioux, Rinse K Weersma, Andre Franke, Luke Jostins, Carl A Anderson, Jeffrey C Barrett, Daniel G MacArthur, Chaim Jalas, Harry Sokol, Ramnik J Xavier, Ann Pulver, Judy H Cho, Dermot P B McGovern, Mark J Daly
Publikováno v:
PLoS Genetics, Vol 15, Iss 5, p e1008190 (2019)
PLoS Genetics
PLoS Genetics
As part of a broader collaborative network of exome sequencing studies, we developed a jointly called data set of 5,685 Ashkenazi Jewish exomes. We make publicly available a resource of site and allele frequencies, which should serve as a reference f
Autor:
Erik Corona, Simon Gravel, Christopher R. Gignoux, Laura R. Botigué, Edward R. Burns, Brian K. Maples, Harry Ostrer, Brenna M. Henn, Carlos Flores, Gil Atzmon, Carlos Bustamante, David Comas, Jaume Bertranpetit
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Botigué, Laura R. et al.
Human genetic diversity in southern Europe is higher than in other regions of the continent. This difference has been attributed to postglacial expansions, the demic diffusion of agriculture from the Near East, and gene
Human genetic diversity in southern Europe is higher than in other regions of the continent. This difference has been attributed to postglacial expansions, the demic diffusion of agriculture from the Near East, and gene