Zobrazeno 1 - 10
of 41
pro vyhledávání: '"George Hsiao"'
Autor:
George Hsiao, Chen Yao Su, Yueh Lun Lee, Ying Hua Shieh, Thierry Burnouf, Lin Wen Lee, Yi Yuan Yang, Sy Jye Leu
Publikováno v:
Transfusion. 53:1918-1928
Background Platelet concentrate lysates (PCLs) are increasingly used in regenerative medicine. We have developed a solvent/detergent (S/D)-treated PCL. The functional properties of this preparation should be unveiled. We hypothesized that, due to tra
Autor:
Chih-Jen Wu, Thanasekaran Jayakumar, George Hsiao, Ting-Lin Yen, Jui-Tai Chen, Joen Rong Sheu, Duen-Suey Chou
Publikováno v:
Evidence-Based Complementary and Alternative Medicine, Vol 2011 (2011)
Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-based Complementary and Alternative Medicine : eCAM
Tao-Hong-Si-Wu-Tang (THSWT) is a famous traditional Chinese medicine (TMC). In the present study, oral administration of THSWT (0.7 and 1.4 gkg−1day−1) for 14 days before MCAO dose-dependently attenuated focal cerebral ischemia in rats. MCAO-indu
Publikováno v:
Pharmacological Research. 57:151-158
The amyloid beta peptide (Abeta), a mediator of neuronal and vascular degeneration in the pathogenesis of Alzheimer's disease and cerebral amyloid angiopathy may have peripheral actions. Platelets are enriched with Abeta and have been shown to enhanc
Autor:
Kuang H. Lin, Tsorng H. Fong, Chia H. Shen, Joen R. Sheu, Duen S. Chou, George Hsiao, Jie J. Lee
Publikováno v:
Cardiovascular Research. 75:782-792
Caffeic acid phenethyl ester (CAPE), which is derived from the propolis of honeybee hives, has been demonstrated to possess multiple pharmacological activities. In the present study, CAPE (6-25 microM) specifically inhibited collagen-induced platelet
Publikováno v:
European Journal of Pharmacology. 537:52-58
The intracellular mechanisms underlying the signaling pathways of activated matrix metalloproteinase-9 (MMP-9) in platelets are not yet completely understood. Therefore, the aim of this study was to further examine the effects of activated MMP-9 in p
Autor:
Kuang Hung Lin, Duen Suey Chou, Tsorng Hang Fong, George Hsiao, Ming Yi Shen, Joen Rong Sheu, Ying Wang, Nien Hsuan Tzu
Publikováno v:
Journal of Laboratory and Clinical Medicine. 146:216-226
Lycopene is a natural carotenoid antioxidant that is present in tomatoes and tomato products. The pharmacologic function of lycopene in platelets is not yet understood. Therefore, in this study we sought to systematically examine the effects of lycop
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 25:1998-2004
Objective— Inosine is a naturally occurring nucleoside degraded from adenosine. Recent studies have demonstrated that inosine has potent immunomodulatory and neuroprotective effects. In the present study, we further investigated the inhibitory effe
Publikováno v:
Free Radical Biology and Medicine. 39:237-248
Several free radical intermediates formed during synthesis of prostaglandin H synthase (PGHS) catalyze the biosynthesis of prostaglandins from arachidonic acid (AA). We attempted to directly detect free radical intermediates of PGHS in cells. Studies
Autor:
Gong Jhe Wu, Chien-Huang Lin, Ming Yi Shen, George Hsiao, Joen Rong Sheu, Duen Suey Chou, Yi Chang, Ta Liang Chen, Kuan Hung Lin
Publikováno v:
Journal of Biomedical Science. 11:764-772
The aim of this study was to systematically examine the inhibitory mechanisms of ketamine in platelet aggregation. In this study, ketamine concentration-dependently (100-350 microM) inhibited platelet aggregation both in washed human platelet suspens
Autor:
Tsorng-Harn Fong, Ming Y. Shen, Meng S. Lu, Yi Chang, Joen Rong Sheu, Ta-Liang Chen, Cheng-Ming Liu, George Hsiao
Publikováno v:
British Journal of Pharmacology. 143:193-201
1. The aim of this study was to identify the presence of matrix metalloproteinase-9 (MMP-9) in human platelets and systematically examine its inhibitory mechanisms of platelet activation. 2. In this study, we report on an efficient method for the qua