Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Reinaldo N. Takahashi"'
Autor:
Fernanda da Rosa, Nuno J. Machado, Pablo Pandolfo, Cristiane Ribeiro de Carvalho, Carolina Melo de Souza, Lisiane O. Porciúncula, Rodrigo A. Cunha, Douglas Teixeira Leffa, Grasielle C. Kincheski, Diogo O. Souza, Samira G. Ferreira, Reinaldo N. Takahashi
Publikováno v:
European Journal of Neuroscience. 49:1673-1683
Attention deficit and hyperactivity disorder (ADHD) is characterized by impaired levels of hyperactivity, impulsivity, and inattention. Adenosine and endocannabinoid systems tightly interact in the modulation of dopamine signaling, involved in the ne
Autor:
Cristina A J, Stern, Thiago R, da Silva, Ana M, Raymundi, Camila P, de Souza, Vinicius A, Hiroaki-Sato, Luiza, Kato, Francisco S, Guimarães, Roberto, Andreatini, Reinaldo N, Takahashi, Leandro J, Bertoglio
Publikováno v:
Neuropharmacology. 125
Pharmacological interventions able to modulate a fear memory while it is consolidated could have therapeutic value in tempering those maladaptively overconsolidated. Animal and human studies have shown the intensity of unconditioned stimulus delivere
Publikováno v:
European Neuropsychopharmacology. 24:1091-1102
The endocannabinoid (eCB) and glucocorticoid systems contribute to the modulation of emotional states. Noteworthy, glucocorticoid hormones are released by adrenal glands during stressful events and endocannabinoids are released in the brain during fe
Autor:
Rafael Mariano de Bitencourt, Juliana A.V. Kroon, Rimenez R. Souza, Fabricio Hoffmann Martins Do Monte, Reinaldo N. Takahashi
Publikováno v:
Behavioural Brain Research. 250:23-27
Previous studies have implicated cannabinoids in extinction of conditioned fear. We have recently showed that intraventricular infusion of the phytocannabinoid cannabidiol (CBD) facilitates fear extinction, but the brain regions underlying this effec
Autor:
Carla I. Tasca, Carina Akemi Nakamura, Tetsadê C. B. Piermartiri, Reinaldo N. Takahashi, Fabrício Luiz Assini
Publikováno v:
Behavioural Pharmacology. 23:292-301
The aim of this study was to characterize the interaction of adenosine A1-receptor and cannabinoid CB1-receptor antagonists in the water maze and object-location tasks, and to evaluate the participation of glutamatergic neurotransmission in the hippo
Publikováno v:
Psychopharmacology. 188:641-649
Rationale Previous studies demonstrated that pharmacological blockade of CB1 cannabinoid receptors decreases the extinction of conditioned fear and spatial memory in rodents. However, the effects of CB1 cannabinoid receptor activation in this respons
Publikováno v:
Neuroscience Letters. 380:270-275
Δ9-THC and synthetic cannabinoids produce memory impairment in humans as well as in laboratory animals. The high concentration of cannabinoid CB1 receptors and the presence of endocannabinoids in the hippocampus suggest that a cannabinoid neurochemi
Publikováno v:
Neuroscience Letters. 349:49-52
The effect of systemic administration of the cannabinoid antagonist SR 141716A (N-(piperidin-1-yl)-5-(4-chlorophenyl)-4-methyl-1H-pyrazole-3-carboxyamide) on penile erection and yawning induced by apomorphine was investigated in rats. SR 141716A (2 m
Publikováno v:
Pharmacology Biochemistry and Behavior. 75:763-768
Cannabinoid receptor agonists significantly inhibit nociceptive responses in a large number of animal models. The present study examined whether mice displaying different basal levels of anxiety in the plus-maze test of anxiety might differ in terms
Publikováno v:
Neuroscience letters. 470(1)
Evidence are that inhibition of cyclooxygenase 2 (COX-2) enhances endocannabinoid signaling, indicating a crosstalk between these two eicosanoid pathways. Aspirin, a non-selective COX inhibitor, acetylates COX-2 with generation of a lipoxygenase (LOX