Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Martín, Hugo"'
Publikováno v:
Free Radical Biology and Medicine. 177:S103-S104
Publikováno v:
Free radical biology and medicine, 160:293-302
The proteasomal degradation system is one of the most important protein degradation systems in the cytosol and nucleus. This system is present in two major forms: the ATP-stimulated 26S/30 S proteasome or the ATP-independent 20S core proteasome. Whil
Publikováno v:
Free Radical Biology and Medicine. 165:27
Autor:
Julia Bornhorst, José Pedro Castro, Veronika Somoza, Tanja Schwerdtle, Martín Hugo, Kerstin Nowotny, Tilman Grune, Daniela Weber, Sabine Braune, Marc Pignitter
Methylglyoxal (MG), a highly reactive dicarbonyl, interacts with proteins to form advanced glycation end products (AGEs). AGEs include a variety of compounds which were shown to have damaging potential and to accumulate in the course of different con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40eeda4387d343bfdecc14604f9b42a
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/52884
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/52884
Autor:
Diego S. Vazquez, Madia Trujillo, Martín Hugo, Rafael Radi, Javier Santos, Darío A. Estrin, María Inés De Armas, M. Dolores Piñeyro, Aníbal M. Reyes, Ari Zeida
Publikováno v:
Advances in Free Radical Biology & Medicine
Advances in Free Radical Biology & Medicine, Elsevier, 2015, 101, pp.249-260. ⟨10.1016/j.freeradbiomed.2016.10.005⟩
Advances in Free Radical Biology & Medicine, Elsevier, 2015, 101, pp.249-260. ⟨10.1016/j.freeradbiomed.2016.10.005⟩
Mycobacterium tuberculosis (M. tuberculosis) is the intracellular bacterium responsible for tuberculosis disease (TD). Inside the phagosomes of activated macrophages, M. tuberculosis is exposed to cytotoxic hydroperoxides such as hydrogen peroxide, f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042d66280e8ec1abf7a3e210176328d6
https://www.sciencedirect.com/science/article/pii/S0891584916304476
https://www.sciencedirect.com/science/article/pii/S0891584916304476
Autor:
José Pedro Castro, André Kleinridders, Kerstin Nowotny, Tobias Jung, Tilman Grune, Raquel Fernando, Martín Hugo, Kristina Wardelmann
Publikováno v:
Free Radical Biology and Medicine. 108:S35
The white adipose tissue (WAT) is crucial for maintaining metabolism homeostasis by storing lipids and/or by secreting adipokines. A healthy WAT relies on continuous renewal, through a multi-step process called adipogenesis. Upon failure, the risk fo
Publikováno v:
Free Radical Biology and Medicine. 108:S95
Type 2 diabetes is a chronic metabolic disorder characterized, among other features, by elevated levels of circulatory free fatty acids. Several studies in animal and cellular models indicate that increased accumulation of lipids leads to oxidative a
Autor:
Leticia Prates Roma, Tilman Grune, Antonio Martínez-Ruiz, Martín Hugo, Carmen García, Ioana Korovila, Anabel Marina
Publikováno v:
Free Radical Biology and Medicine. 108:S100
The main machinery responsible for cellular protein maintenance is the ubiquitin-proteasomal system. The main task of the system is a fast and efficient degradation of proteins not needed anymore in cellular metabolism. It is accepted that upon oxida
Autor:
Tilman Grune, Martín Hugo
Publikováno v:
Free Radical Biology and Medicine. 86:S42
Protein degradation by the 26S proteasome is a fundamental process involved in a broad range of cellular activities, yet how proteasome activity is regulated remains poorly understood. In particular, the mechanisms of redox-dependent regulation of th
Autor:
Madia Trujillo, Andrés Trostchansky, Aníbal M. Reyes, Luciana Capece, Rafael Radi, Martín Hugo
Alkyl hydroperoxide reductase E (AhpE), a novel subgroup of the peroxiredoxin family, comprises Mycobacterium tuberculosis AhpE (MtAhpE) and AhpE-like proteins present in many bacteria and archaea, for which functional characterization is scarce. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39f80b71e01209674acdcd19e8ed803e
http://www.sciencedirect.com/science/article/pii/S0891584911002498
http://www.sciencedirect.com/science/article/pii/S0891584911002498