Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jochen Steppan"'
Autor:
Jochen Steppan, Kavitha Nandakumar, Huilei Wang, Rosie Jang, Logan Smith, Sara Kang, William Savage, Maria Bauer, Rira Choi, Travis Brady, Bulouere Princess Wodu, Susanna Scafidi, Joseph Scafidi, Lakshmi Santhanam
Publikováno v:
Physiological Reports. 11
Autor:
Jochen Steppan, Sandeep Jandu, William Savage, Huilei Wang, Sara Kang, Roshini Narayanan, Daniel Nyhan, Lakshmi Santhanam
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Frontiers in Physiology
Frontiers in Physiology
BackgroundHypertension is a well-established driver of vascular remodeling and stiffening. The goal of this study was to evaluate whether restoring normal blood pressure (BP) fully restores vascular stiffness toward that of normotensive controls.Meth
Autor:
Siqi Tan, Sebastian F. Barreto-Ortiz, Robert N. Cole, Huilei Wang, Dan E. Berkowitz, Tatiana Boronina, Marc K. Halushka, Sandeep Jandu, Lakshmi Santhanam, Marcel J. Rauer, Kavitha Nandakumar, Steven S. An, Wanqu Zhu, Yehudit Bergman, Jochen Steppan
Publikováno v:
Am J Physiol Heart Circ Physiol
Vascular stiffening and its sequelae are major causes of morbidity and mortality in the elderly. The increasingly accepted concept of “smooth muscle cell (SMC) stiffness syndrome” along with matrix deposition has emerged in vascular biology to ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a310d0ecc15dbdc1f1fc3c708a42140
https://europepmc.org/articles/PMC6692735/
https://europepmc.org/articles/PMC6692735/
Autor:
Ananya Tripathi, Yurie Obata, Pavel Ruzankin, Narwan Askaryar, Dan E. Berkowitz, Jochen Steppan, Viachaslau Barodka
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Frontiers in Physiology
Frontiers in Physiology
Background: Constant blood flow despite changes in blood pressure, a phenomenon called autoregulation, has been demonstrated for various organ systems. We hypothesized that by changing hydrostatic pressures in peripheral arteries, we can establish th
Autor:
Daniel Nyhan, Jochen Steppan, Qi J. Ong, Yurie Obata, Helen Grichkevitch, Dan E. Berkowitz, Viachaslau Barodka, J. Magruder
Publikováno v:
Frontiers in Physiology
Background: The effects of position and exercise on pulse wave distribution across a healthy, compliant arterial tree are not fully understood. We studied the effects of exercise and position on the pattern of pulse arrival times (PATs) in healthy vo
Publikováno v:
Free Radical Biology and Medicine. 112:118-119
Introduction Reduced nitric oxide (NO) bioavailability and increased generation of reactive oxygen species and inflammation with advancing age play a major role in the development of cardiovascular disease (CVD) risk factors of hypertension, endothel
Autor:
Steven S. An, Mark Butlin, Daniel Nyhan, Simran K. Jandu, Kayla Viegas, Alberto Avolio, Eric Y Choi, Dan E. Berkowitz, Alina Pak, Sung Mee Jung, Alexey M. Belkin, Lakshmi Santhanam, Jochen Steppan
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 305(6)
Nitric oxide (NO) can modulate arterial stiffness by regulating both functional and structural changes in the arterial wall. Tissue transglutaminase (TG2) has been shown to contribute to increased central aortic stiffness by catalyzing the cross-link
Autor:
Mehnaz, Khan, Jochen, Steppan, Karl H, Schuleri, Karl, Schuleri, Sungwoo, Ryoo, Eric, Tuday, Lukasz, Bugaj, Lakshmi, Santhanam, Tal, Berkowitz, Daniel, Nyhan, Artin A, Shoukas, Dan E, Berkowitz
Publikováno v:
European journal of applied physiology. 112(8)
Arginase-II (Arg-II) reciprocally regulates nitric oxide synthase (NOS) and offsets basal myocardial contractility. Furthermore, decreased or absent myocardial NOS activity is associated with a depression in myocardial contractile reserve. We therefo
Autor:
Jochen Steppan, Eric C. Tuday, Daniel Nyhan, Artin A. Shoukas, Dan E. Berkowitz, Mehnaz Khan, Lukasz J. Bugaj, Lakshmi Santhanam, Sungwoo Ryoo, Karl H. Schuleri, Tal Berkowitz
Publikováno v:
European Journal of Applied Physiology. 112:4189-4189
The online version of the original article can be found underdoi:10.1007/s00421-011-2257-9.M.Khan J.Steppan S.Ryoo L.Santhanam T.Berkowitz D. Nyhan D. E. Berkowitz (&)Department of Anesthesiology and Critical Care Medicine,Johns Hopkins University Me