Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Barbara McKnight"'
Autor:
Suraj Dahal, Peilin Shi, Meng Wang, Will Longstreth, Heidi Lai, Rozenn Lemaitre, David S Siscovick, Barbara McKnight, Amanda M Fretts, Marcia D Otto, Nona Sotoodehnia, W. H. Wilson Tang, Stanley L Hazen, Dariush Mozaffarian, Matthew J Budoff
Publikováno v:
Circulation. 144
Introduction: Findings on MRI of vascular brain injury, such as brain infarcts and white matter hyperintensities, are chronic manifestation of atherosclerosis. A gut-microbiome-generated metabolite, trimethylamine N-oxide (TMAO), is an independent pr
Autor:
Lin Y. Chen, Bruce M. Psaty, Susan R. Heckbert, Elsayed Z. Soliman, Barbara McKnight, Faye L. Norby, Barbara N Harding, James S. Floyd
Publikováno v:
Circulation. 143
Purpose: High blood pressure (BP) is a well-known risk factor for atrial fibrillation (AF), but a single BP measurement may provide limited information about AF risk in older adults. We evaluated whether longitudinal measures of BP were associated wi
Autor:
Amanda M. Fretts, Paul N. Jensen, David S. Siscovick, Nona Sotoodehnia, Irena B. King, Andrew N. Hoofnagle, Colleen M. Sitlani, Barbara McKnight, Rozenn N. Lemaitre, Bruce M. Psaty
Publikováno v:
Circulation. 141
Introduction: Recent studies suggest that the type of saturated fatty acid bound to sphingolipids influences sphingolipid activity, and that associations of ceramides (Cer) and sphingomyelins (SM) with cardiovascular outcomes may differ by lipid spec
Autor:
Nita G. Forouhi, Kim Overvad, Lars Lind, Robert Luben, Paulo H M Chaves, Woon-Puay Koh, Matti Marklund, Catherine Helmer, Johan Sundström, Kiesha Prem, Jaakko Mursu, Kerry L. M. Wong, Ingeborg A. Brouwer, Paul F. Jacques, Anya Kalsbeek, Mark Woodward, Helle Højmark Eriksen, Matthias B. Schulze, J.M.A. Boer, Peilin Shi, Wei Sin Yang, Eric B. Rimm, William S. Harris, Eliseo Guallar, Frank B. Hu, Kay-Tee Khaw, Jian-Min Yuan, Xia Zhou, Luc Djoussé, Maria Lankinen, Juhua Luo, W. M. Monique Verschuren, Barbara McKnight, Alexis C. Wood, Marcia C de Oliveira Otto, Tzu An Chen, Mai Lis Hellénius, Jason H Y Wu, Walter C. Willett, Matti Uusitupa, Hannia Campos, Federica Laguzzi, Bruna Gigante, Rozenn N. Lemaitre, David S. Siscovick, Brian T. Steffen, Johanna M. Geleijnse, Karin Leander, Hung-Ju Lin, Renata Micha, Hugh Tunstall-Pedoe, Ulf Risérus, Allison M. Hodge, Tamara B. Harris, Janette de Goede, Ana Baylin, Amanda M. Fretts, J. Michael Gaziano, Nicholas J. Wareham, Liana C Del Gobbo, Maria Wennberg, Bruce M. Psaty, Graham G. Giles, Qi Sun, Stella Aslibekyan, Toshiharu Ninomiya, Fumiaki Imamura, Vilmundur Gudnason, Michael Y. Tsai, Cécilia Samieri, Nathan L. Tintle, Rachel A. Murphy, Lyn M. Steffen, Janine Kröger, Rob M. van Dam, Kuo-Liong Chien, Albert V. Smith, Naglaa El-Abbadi, Yoichiro Hirakawa, Jyrki K. Virtanen, Markku Laakso, Dariush Mozaffarian, Ulf de Faire, Michael S. Nielsen, Jan-Håkan Jansson, Gudny Eiriksdottir, Jenna Veenstra
Publikováno v:
Circulation 139 (2019) 21
Marklund, M, Wu, J H Y, Imamura, F, Del Gobbo, L C, Fretts, A, de Goede, J, Shi, P, Tintle, N, Wennberg, M, Aslibekyan, S, Chen, T-A, de Oliveira Otto, M C, Hirakawa, Y, Eriksen, H H, Kröger, J, Laguzzi, F, Lankinen, M, Murphy, R A, Prem, K, Samieri, C, Virtanen, J, Wood, A C, Wong, K, Yang, W-S, Zhou, X, Baylin, A, Boer, J M A, Brouwer, I A, Campos, H, Chaves, P H M, Chien, K-L, de Faire, U, Djoussé, L, Eiriksdottir, G, El-Abbadi, N, Forouhi, N G, Gaziano, J M, Geleijnse, J M, Gigante, B, Giles, G, Guallar, E, Gudnason, V, Harris, T, Harris, W S, Helmer, C, Hellénius, M-L, Hodge, A, Hu, F B, Jacques, P F, Jansson, J-H, Kalsbeek, A, Khaw, K-T, Koh, W-P, Laakso, M, Leander, K, Lin, H-J, Lind, L, Luben, R, Luo, J, McKnight, B, Mursu, J, Ninomiya, T, Overvad, K, Psaty, B M, Rimm, E, Schulze, M B, Siscovick, D, Skjelbo Nielsen, M R, Smith, A V, Steffen, B T, Steffen, L, Sun, Q, Sundström, J, Tsai, M Y, Tunstall-Pedoe, H, Uusitup, M I J, van Dam, R M, Veenstra, J, Verschuren, W M M, Wareham, N, Willett, W, Woodward, M, Yuan, J-M, Micha, R, Lemaitre, R N, Mozaffarian, D, Risérus, U & Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCE) 2019, ' Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality : An Individual-Level Pooled Analysis of 30 Cohort Studies ', Circulation, vol. 139, no. 21, pp. 2422-2436 . https://doi.org/10.1161/CIRCULATIONAHA.118.038908
Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCE) 2019, ' Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality : An Individual-Level Pooled Analysis of 30 Cohort Studies ', Circulation, vol. 139, no. 21, pp. 2422-2436 . https://doi.org/10.1161/CIRCULATIONAHA.118.038908
Overvad, K & Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCE) 2019, ' Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality : An Individual-Level Pooled Analysis of 30 Cohort Studies ', Circulation, vol. 139, no. 21, pp. 2422-2436 . https://doi.org/10.1161/CIRCULATIONAHA.118.038908
Circulation, 139(21), 2422-2436
Circulation
Marklund, M, Wu, J H Y, Imamura, F, Del Gobbo, L C, Fretts, A, de Goede, J, Shi, P, Tintle, N, Wennberg, M, Aslibekyan, S, Chen, T-A, de Oliveira Otto, M C, Hirakawa, Y, Eriksen, H H, Kröger, J, Laguzzi, F, Lankinen, M, Murphy, R A, Prem, K, Samieri, C, Virtanen, J, Wood, A C, Wong, K, Yang, W-S, Zhou, X, Baylin, A, Boer, J M A, Brouwer, I A, Campos, H, Chaves, P H M, Chien, K-L, de Faire, U, Djoussé, L, Eiriksdottir, G, El-Abbadi, N, Forouhi, N G, Gaziano, J M, Geleijnse, J M, Gigante, B, Giles, G, Guallar, E, Gudnason, V, Harris, T, Harris, W S, Helmer, C, Hellénius, M-L, Hodge, A, Hu, F B, Jacques, P F, Jansson, J-H, Kalsbeek, A, Khaw, K-T, Koh, W-P, Laakso, M, Leander, K, Lin, H-J, Lind, L, Luben, R, Luo, J, McKnight, B, Mursu, J, Ninomiya, T, Overvad, K, Psaty, B M, Rimm, E, Schulze, M B, Siscovick, D, Skjelbo Nielsen, M R, Smith, A V, Steffen, B T, Steffen, L, Sun, Q, Sundström, J, Tsai, M Y, Tunstall-Pedoe, H, Uusitup, M I J, van Dam, R M, Veenstra, J, Verschuren, W M M, Wareham, N, Willett, W, Woodward, M, Yuan, J-M, Micha, R, Lemaitre, R N, Mozaffarian, D, Risérus, U & Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCE) 2019, ' Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality : An Individual-Level Pooled Analysis of 30 Cohort Studies ', Circulation, vol. 139, no. 21, pp. 2422-2436 . https://doi.org/10.1161/CIRCULATIONAHA.118.038908
Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCE) 2019, ' Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality : An Individual-Level Pooled Analysis of 30 Cohort Studies ', Circulation, vol. 139, no. 21, pp. 2422-2436 . https://doi.org/10.1161/CIRCULATIONAHA.118.038908
Overvad, K & Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCE) 2019, ' Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality : An Individual-Level Pooled Analysis of 30 Cohort Studies ', Circulation, vol. 139, no. 21, pp. 2422-2436 . https://doi.org/10.1161/CIRCULATIONAHA.118.038908
Circulation, 139(21), 2422-2436
Circulation
Background: Global dietary recommendations for and cardiovascular effects of linoleic acid, the major dietary omega-6 fatty acid, and its major metabolite, arachidonic acid, remain controversial. To address this uncertainty and inform international r
Autor:
Jason H Y Wu, Rozenn N. Lemaitre, Marcia C de Oliveira Otto, David S. Siscovick, Evan L. Thacker, Barbara McKnight, Dariush Mozaffarian, Irena B. King, Oscar L. Lopez, Xiaoling Song, Heidi Lai, Nikhil S. Padhye
Publikováno v:
Circulation. 139
Background: Polyunsaturated fatty acids (PUFA) are essential nutrients for normal brain function, constituting nearly 35% of brain lipids. Experimental studies suggest that omega-3 and omega-6 PUFA, present in plant foods and fish, may reduce risk of
Autor:
Mariza de Andrade, Nicholas L. Smith, Kenneth Rice, James S. Pankow, Cathy C. Laurie, Amanda A. Seyerle, Charles Kooperberg, Cecelia A. Laurie, Brandon J. Coombes, Weihong Tang, Barbara McKnight, Tamar Sofer
Publikováno v:
Circulation. 137
Background: The Trans-Omics for Precision Medicine (TOPMed) program is performing whole-genome sequencing across multiple studies, including longitudinal cohorts, case-control, and case-only sample sets. Detecting the effects of low frequency variant
Autor:
Heidi T Lai, Marcia C de Oliveira Otto, Jason H Wu, Yujin Lee, Xiaoling Song, Irena B King, Bruce M Psaty, Rozenn N Lemaitre, Barbara McKnight, David S Siscovick, Dariush Mozaffarian
Publikováno v:
Circulation. 137
De novo lipogenesis (DNL) is a crucial metabolic pathway that convert excess carbohydrates to fatty acids (FA) for energy and storage. Both DNL and the synthesized FA have biologic effects that may affect cardiometabolic risk. Yet, the association be
Autor:
Rozenn N Lemaitre, Mary L Biggs, Barbara McKnight, Heidi T Lai, Xiaoling Song, Irena B King, Bruce M Psaty, David S Siscovick, Dariush Mozaffarian
Publikováno v:
Circulation. 137
Introduction: Circulating very long-chain saturated fatty acids (VLSFA) are biomarkers of diet and metabolism which impart different biological activities to sphingolipids and may influence physiological pathways relevant to aging. Higher levels of c
Autor:
Rozenn N Lemaitre, Paul N Jensen, Barbara McKnight, Andrew Hoofnagle, Irena B King, Susan R Heckbert, Nona Sotoodehnia, Dariush Mozaffarian, Bruce M Psaty
Publikováno v:
Circulation. 137
Introduction: Ceramides and sphingomyelins (sphingolipids) are circulating lipids involved in multiple physiological pathways relevant to heart failure (HF) and atrial fibrillation (AF), including apoptosis, oxidative stress, and inflammation. Experi
Autor:
Thomas R. Austin, Jiankang Liu, Adolfo Correa, Yi Yang, Chad Blackshear, Kerri L. Wiggins, Alvaro Alonso, Nona Sotoodehnia, Lesley H. Curtis, Barbara McKnight, Emelia J. Benjamin, Benjamin F. Banahan, Jingzhong Ding, Susan R. Heckbert
Publikováno v:
Circulation. 133
Introduction: Obesity is associated with higher risk of incident AF, but the underlying mechanisms are not well understood. Increased pericardial fat deposition may lead to atrial fibrosis and renin-angiotensin system activation due to free diffusion