Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Tore Bengtsson"'
Autor:
Masaaki, Sato, Bronwyn A, Evans, Anna L, Sandström, Ling Yeong, Chia, Saori, Mukaida, Bui San, Thai, Anh, Nguyen, Linzi, Lim, Christina Y R, Tan, Jo-Anne, Baltos, Paul J, White, Lauren T, May, Dana S, Hutchinson, Roger J, Summers, Tore, Bengtsson
Publikováno v:
Biochemical pharmacology. 148
The capacity of G protein-coupled receptors to modulate mechanistic target of rapamycin (mTOR) activity is a newly emerging paradigm with the potential to link cell surface receptors with cell survival. Cardiomyocyte viability is linked to signalling
Autor:
Julia Nevzorova, Tore Bengtsson, Jon Merlin, Olof S. Dallner, Roger J. Summers, Nodi Dehvari, Dana S. Hutchinson, Masaaki Sato, Bronwyn A Evans, Martina Kocan
Publikováno v:
British Journal of Pharmacology. 165:1442-1456
BACKGROUND AND PURPOSE β-Adrenoceptor stimulation induces glucose uptake in several insulin-sensitive tissues by poorly understood mechanisms. EXPERIMENTAL APPROACH We used a model system in CHO-K1 cells expressing the human β2-adrenoceptor and glu
Publikováno v:
Diabetologia. 50:158-167
In skeletal muscle, the storage of glycogen by insulin is regulated by glycogen synthase, which is regulated by glycogen synthase kinase 3 (GSK3). Here we examined whether adrenergic receptor activation, which can increase glucose uptake, regulates g
Autor:
Dana S. Hutchinson, Tore Bengtsson
Publikováno v:
Diabetes. 55:682-690
AMP-activated protein kinase (AMPK), which functions as a sensor of cellular energy homeostasis, was phosphorylated after norepinephrine stimulation in L6 skeletal muscle cells. This effect was mediated by alpha1-adrenoceptors, with no stimulatory ef
Autor:
Tore Bengtsson, Didier F. Pisani, Dana S. Hutchinson, Jean-Claude Chambard, Anna L. Sandström, Ez-Zoubir Amri, Jessica M. Olsen, Masaaki Sato, Olof S. Dallner
Publikováno v:
The Journal of Cell Biology
Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2014, 207 (3), pp.365-74
Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2014, 207 (3), pp.365-74
β3-Adrenoceptors promote glucose uptake in brown adipose tissue via both cAMP-mediated increases in GLUT1 transcription and mTORC2-stimulated translocation of newly synthesized GLUT1 to the plasma membrane.
Brown adipose tissue is the primary s
Brown adipose tissue is the primary s
Publikováno v:
Diabetologia. 48:2386-2395
Brown adipocytes provide a potentially important model system for understanding AMP-activated protein kinase (AMPK) regulation, where adrenergic stimulation leads to mitochondrial uncoupling through uncoupling protein-1 (UCP1) activity. AMPK is a sen
Autor:
Olof S. Dallner, Tore Bengtsson, Nodi Dehvari, Roger J. Summers, Robert I. Csikasz, Dana S. Hutchinson, Masaaki Sato, Anna L. Sandström, Jessica M. Olsen, Anette I. Öberg
Publikováno v:
Diabetes. 63(12)
There is an increasing worldwide epidemic of type 2 diabetes that poses major health problems. We have identified a novel physiological system that increases glucose uptake in skeletal muscle but not in white adipocytes. Activation of this system imp
Publikováno v:
Experimental cell research. 328(1)
The physiological agonist norepinephrine promotes cell proliferation of brown preadipocytes during the process of tissue recruitment. In a primary culture system, cAMP mediates these adrenergic effects. In the present study, we demonstrated that, in
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22304 (2011)
PLoS ONE
PLoS ONE
The β-adrenoceptors (β-ARs) control many cellular processes. Here, we show that β-ARs inhibit calcium depletion-induced cell contractility and subsequent cell detachment of L6 skeletal muscle cells. The mechanism underlying the cell detachment inh
Autor:
Mona Wilcke, Claes-Göran Östenson, Robert I. Csikasz, Nodi Dehvari, Anette I. Öberg, Dana S. Hutchinson, Tore Bengtsson, Kamal Yassin, Irina G. Shabalina
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22510 (2011)
PLoS ONE
PLoS ONE
BACKGROUND: There is considerable interest in identifying compounds that can improve glucose homeostasis. Skeletal muscle, due to its large mass, is the principal organ for glucose disposal in the body and we have investigated here if shikonin, a nap