Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Guillaume, Lenoir"'
Publikováno v:
Lyons, J A, Timcenko, M, Dieudonné, T, Lenoir, G & Nissen, P 2020, ' P4-ATPases : how an old dog learnt new tricks — structure and mechanism of lipid flippases ', Current Opinion in Structural Biology, vol. 63, pp. 65-73 . https://doi.org/10.1016/j.sbi.2020.04.001
Type 4 P-type ATPases (P4-ATPases) are lipid flippases that drive the active, inward directed translocation (flip) of lipids in eukaryotic membranes. The resulting lipid asymmetry potentiates the membrane and is essential for a wide range of cellular
Publikováno v:
BBA-Biochimica et Biophysica Acta
BBA-Biochimica et Biophysica Acta, Elsevier, 2016, pp.767-83. 〈10.1016/j.bbalip.2015.12.020〉
BBA-Biochimica et Biophysica Acta, Elsevier, 2016, pp.767-83. ⟨10.1016/j.bbalip.2015.12.020⟩
Montigny, C, Lyons, J, Champeil, P, Nissen, P & Lenoir, G 2016, ' On the molecular mechanism of flippase-and scramblase-mediated phospholipid transport ', B B A-Molecular and Cell Biology of Lipids, vol. 1861, no. 8, Part B . https://doi.org/10.1016/j.bbalip.2015.12.020
BBA-Biochimica et Biophysica Acta, 2016, pp.767-83. ⟨10.1016/j.bbalip.2015.12.020⟩
BBA-Biochimica et Biophysica Acta, Elsevier, 2016, pp.767-83. 〈10.1016/j.bbalip.2015.12.020〉
BBA-Biochimica et Biophysica Acta, Elsevier, 2016, pp.767-83. ⟨10.1016/j.bbalip.2015.12.020⟩
Montigny, C, Lyons, J, Champeil, P, Nissen, P & Lenoir, G 2016, ' On the molecular mechanism of flippase-and scramblase-mediated phospholipid transport ', B B A-Molecular and Cell Biology of Lipids, vol. 1861, no. 8, Part B . https://doi.org/10.1016/j.bbalip.2015.12.020
BBA-Biochimica et Biophysica Acta, 2016, pp.767-83. ⟨10.1016/j.bbalip.2015.12.020⟩
International audience; Phospholipid flippases are key regulators of transbilayer lipid asymmetry in eukaryotic cell membranes, critical to many trafficking and signaling pathways. P4-ATPases, in particular, are responsible for the uphill transport o
Autor:
Philippe Champeil, Pierre Le Maréchal, Joseph A. Lyons, Poul Nissen, José Luis Vázquez-Ibar, Cédric Montigny, Aurore Jacquot, Thibaud Dieudonné, Jakob Ulstrup, Miriam-Rose Ash, Guillaume Lenoir, Hassina Azouaoui
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2017, 292 (19), pp.7954-7970. ⟨10.1074/jbc.M116.751487⟩
Journal of Biological Chemistry, 2017, 292 (19), pp.7954-7970. ⟨10.1074/jbc.M116.751487⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2017, 292 (19), pp.7954-7970. 〈10.1074/jbc.M116.751487〉
Azouaoui, H, Montigny, C, Dieudonné, T, Champeil, P, Jacquot, A, Vázquez-Ibar, J L, le Maréchal, P, Ulstrup, J, Ash, M-R, Lyons, J A, Nissen, P & Lenoir, G 2017, ' A High and Phosphatidylinositol-4-phosphate (PI4P)-dependent ATPase Activity for the Drs2p/Cdc50p Flippase after Removal of its N-and C-terminal Extensions ', Journal of Biological Chemistry, vol. 292, pp. 7954-7970 . https://doi.org/10.1074/jbc.M116.751487
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2017, 292 (19), pp.7954-7970. ⟨10.1074/jbc.M116.751487⟩
Journal of Biological Chemistry, 2017, 292 (19), pp.7954-7970. ⟨10.1074/jbc.M116.751487⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2017, 292 (19), pp.7954-7970. 〈10.1074/jbc.M116.751487〉
Azouaoui, H, Montigny, C, Dieudonné, T, Champeil, P, Jacquot, A, Vázquez-Ibar, J L, le Maréchal, P, Ulstrup, J, Ash, M-R, Lyons, J A, Nissen, P & Lenoir, G 2017, ' A High and Phosphatidylinositol-4-phosphate (PI4P)-dependent ATPase Activity for the Drs2p/Cdc50p Flippase after Removal of its N-and C-terminal Extensions ', Journal of Biological Chemistry, vol. 292, pp. 7954-7970 . https://doi.org/10.1074/jbc.M116.751487
International audience; P4-ATPases, also known as phospholipid flippases, are responsible for creating and maintaining transbilayer lipid asymmetry in eukaryotic cell membranes. Here, we use limited proteolysis to investigate the role of the N and C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78a13bfa67cbd26904683eacf27edde2
https://hal.archives-ouvertes.fr/hal-01697714
https://hal.archives-ouvertes.fr/hal-01697714
Autor:
Cédric Montigny, Thibaud Dieudonné, Stéphane Orlowski, José Luis Vázquez-Ibar, Carole Gauron, Dominique Georgin, Sten Lund, Marc le Maire, Jesper V Møller, Philippe Champeil, Guillaume Lenoir
Publikováno v:
Montigny, C, Dieudonné, T, Orlowski, S, Vázquez-Ibar, J L, Gauron, C, Georgin, D, Lund, S, le Maire, M, Møller, J V, Champeil, P & Lenoir, G 2017, ' Slow Phospholipid Exchange between a Detergent-Solubilized Membrane Protein and Lipid-Detergent Mixed Micelles Brominated Phospholipids as Tools to Follow Its Kinetics ', P L o S One, vol. 12, no. 1, pp. e0170481 . https://doi.org/10.1371/journal.pone.0170481
PLoS ONE
PLoS ONE, 2017, 12 (1), pp.e0170481. ⟨10.1371/journal.pone.0170481⟩
PLoS ONE, Public Library of Science, 2017, 12 (1), pp.e0170481. ⟨10.1371/journal.pone.0170481⟩
PLoS ONE, Vol 12, Iss 1, p e0170481 (2017)
PLoS ONE
PLoS ONE, 2017, 12 (1), pp.e0170481. ⟨10.1371/journal.pone.0170481⟩
PLoS ONE, Public Library of Science, 2017, 12 (1), pp.e0170481. ⟨10.1371/journal.pone.0170481⟩
PLoS ONE, Vol 12, Iss 1, p e0170481 (2017)
Membrane proteins are largely dependent for their function on the phospholipids present in their immediate environment, and when they are solubilized by detergent for further study, residual phospholipids are critical, too. Here, brominated phosphati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8e4b931923f41409563aa208c19c63e8
https://pure.au.dk/portal/da/publications/slow-phospholipid-exchange-between-a-detergentsolubilized-membrane-protein-and-lipiddetergent-mixed-micelles-brominated-phospholipids-as-tools-to-follow-its-kinetics(190cc4fa-0846-4d5d-a513-f65c40e84abf).html
https://pure.au.dk/portal/da/publications/slow-phospholipid-exchange-between-a-detergentsolubilized-membrane-protein-and-lipiddetergent-mixed-micelles-brominated-phospholipids-as-tools-to-follow-its-kinetics(190cc4fa-0846-4d5d-a513-f65c40e84abf).html
Autor:
Catheleyne F. Puts, Jeroen Krijgsveld, Guillaume Lenoir, Patrick Williamson, Joost C. M. Holthuis
Publikováno v:
Journal of Proteome Research. 9:833-842
High-throughput analysis of protein-protein interactions can provide unprecedented insight into how cellular processes are integrated at the molecular level. Yet membrane proteins are often overlooked in these studies owing to their hydrophobic natur
Publikováno v:
Current Opinion in Chemical Biology. 11:654-661
Membrane lipid asymmetry influences a multitude of cellular functions, including membrane vesiculation, cell division, and lifespan. Most cells retain the bulk of aminophospholipids to the cytosolic membrane leaflet by means of ATP-fuelled flippases
Autor:
Paulette Decottignies, Philippe Champeil, Manuel Garrigos, Frank Fijalkowski, Poul Nissen, Guillaume Lenoir, Rosa L. López-Marqués, Hassina Azouaoui, Pontus Gourdon, Miriam-Rose Ash, Christina Grønberg, Cédric Montigny, Michael G. Palmgren, Aurore Jacquot, Marc le Maire
Publikováno v:
PLoS ONE
Azouaoui, H, Montigny, C, Ash, M-R, Fijalkowski, F A, Jacquot, A, Grønberg, C, Lopez Marques, R L, Palmgren, M B, Garrigos, M, le Maire, M, Decottignies, P, Gourdon, P E, Nissen, P, Champeil, P & Lenoir, G 2014, ' A high-yield co-expression system for the purification of an intact drs2p-cdc50p lipid flippase complex, critically dependent on and stabilized by phosphatidylinositol-4-phosphate ', PloS one, vol. 9, no. 11, e112176, pp. 1-16 . https://doi.org/10.1371/journal.pone.0112176
PLoS ONE, 2014, 9 (11), pp.e112176. ⟨10.1371/journal.pone.0112176⟩
Azouaoui, H, Montigny, C, Ash, M-R, Fijalkowski, F, Jacquot, A, Grønberg, C, López-Marqués, R L, Palmgren, M G, Garrigos, M, le Maire, M, Decottignies, P, Gourdon, P, Nissen, P, Champeil, P & Lenoir, G 2014, ' A high-yield co-expression system for the purification of an intact drs2p-cdc50p lipid flippase complex, critically dependent on and stabilized by phosphatidylinositol-4-phosphate ', PLOS ONE, vol. 9, no. 11, e112176 . https://doi.org/10.1371/journal.pone.0112176
PLoS ONE, Public Library of Science, 2014, 9 (11), pp.e112176. ⟨10.1371/journal.pone.0112176⟩
PLoS ONE, Vol 9, Iss 11, p e112176 (2014)
Azouaoui, H, Montigny, C, Ash, M-R, Fijalkowski, F A, Jacquot, A, Grønberg, C, Lopez Marques, R L, Palmgren, M B, Garrigos, M, le Maire, M, Decottignies, P, Gourdon, P E, Nissen, P, Champeil, P & Lenoir, G 2014, ' A high-yield co-expression system for the purification of an intact drs2p-cdc50p lipid flippase complex, critically dependent on and stabilized by phosphatidylinositol-4-phosphate ', PloS one, vol. 9, no. 11, e112176, pp. 1-16 . https://doi.org/10.1371/journal.pone.0112176
PLoS ONE, 2014, 9 (11), pp.e112176. ⟨10.1371/journal.pone.0112176⟩
Azouaoui, H, Montigny, C, Ash, M-R, Fijalkowski, F, Jacquot, A, Grønberg, C, López-Marqués, R L, Palmgren, M G, Garrigos, M, le Maire, M, Decottignies, P, Gourdon, P, Nissen, P, Champeil, P & Lenoir, G 2014, ' A high-yield co-expression system for the purification of an intact drs2p-cdc50p lipid flippase complex, critically dependent on and stabilized by phosphatidylinositol-4-phosphate ', PLOS ONE, vol. 9, no. 11, e112176 . https://doi.org/10.1371/journal.pone.0112176
PLoS ONE, Public Library of Science, 2014, 9 (11), pp.e112176. ⟨10.1371/journal.pone.0112176⟩
PLoS ONE, Vol 9, Iss 11, p e112176 (2014)
International audience; P-type ATPases from the P4 subfamily (P4-ATPases) are energy-dependent transporters, which are thought to establish lipid asymmetry in eukaryotic cell membranes. Together with their Cdc50 accessory subunits, P4-ATPases couple