Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Wayne B. Anderson"'
Publikováno v:
Archives of Biochemistry and Biophysics. 363:121-128
In fibroblasts, the protein kinase C (PKC) activator phorbol 12-myristate 13-acetate (PMA) stimulates phospholipase D (PLD)-mediated hydrolysis of both phosphatidylcholine (PtdCho) and phosphatidylethanolamine (PtdEtn) by PKC-alpha-mediated nonphosph
Publikováno v:
Journal of Neuroscience Research. 39:355-363
At subnanomolar concentrations, vasoactive intestinal peptide (VIP) can act as an astroglial mitogen and as a secretagogue for neurotrophic substances released from glia (Brenneman et al.: J Neurosci Res 25:386–394, 1990). Here we report that treat
Publikováno v:
Biochemical Journal. 302:649-654
The phospholipase D (PLD)-mediated synthesis of phosphatidylethanol (PtdEtOH) and the hydrolysis of phosphatidylethanolamine (PtdEtn) and phosphatidylcholine (PtdCho) were examined in drug-sensitive and multidrug-resistant lines of MCF-7 human breast
Publikováno v:
Journal of Biological Chemistry. 269:4761-4766
To examine the biological properties of protein kinase C (PKC)-delta and -epsilon NIH 3T3 cells were stably transfected with metallothionein-based expression vectors that overexpressed these isoforms. In addition to their inducibility by Zn2+, the pr
Publikováno v:
Analytical Biochemistry. 206:24-35
In the conventional approach protein kinase activity and phorbol ester binding associated with protein kinase C (PKC) are measured by initially incubating samples in either test tubes or multiwell plates, followed by filtration of the terminated reac
Publikováno v:
Archives of biochemistry and biophysics. 397(2)
Phorbol 12-myristate-13-acetate (PMA), a potent tumor promoter and activator of most protein kinase C (PKC) isotypes, was found to significantly inhibit the growth of low population density (1-5% confluency) NIH 3T3 cells. Higher cell population dens
Autor:
Maribeth V. Eiden, Wayne B. Anderson, Betsy D. Leverett, Gyorgy Petrovics, Zoltán Oláh, Zsolt Jobbagy, Nicholas M. Dean
Publikováno v:
The Journal of biological chemistry. 274(11)
The membrane receptors for the gibbon ape leukemia retrovirus and the amphotropic murine retrovirus serve normal cellular functions as sodium-dependent phosphate transporters (Pit-1 and Pit-2, respectively). Our earlier studies established that activ
Publikováno v:
The Biochemical journal. 276
Previously it was reported that transformation of NIH 3T3 fibroblast by the Ha-ras, v-src, v-fms, and A-raf oncogenes decreased the stimulatory effects of phorbol 12-myristate 13-acetate (PMA; ‘TPA’), an activator of protein kinase C (PKC), on th
Publikováno v:
Journal of Biological Chemistry. 261:16438-16445
One of the early events associated with the treatment of cells by tumor promotor phorbol esters is the tight association of protein kinase C to the plasma membrane. To better understand the factors that regulate this process, phorbol ester-induced me
Publikováno v:
FEBS Letters. (1-2):233-237
Exposure of protein kinase C to low concentrations of either N-chlorosuccinimide or H2O2 resulted in rapid and parallel loss of phosphotransferase activity and phorbol ester binding. This oxidative inactivation of protein kinase C also occurred in in