Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Yaowei Zhu"'
Autor:
Honghui Zhou, Wangda Zhou, Yaowei Zhu, Zhenhua Xu, Chuanpu Hu, Michael Song, Amarnath Sharma, Bruce Randazzo
Publikováno v:
Clinical pharmacology and therapeutics. 109(1)
Ustekinumab (STELARA) is a human monoclonal antibody against interleukins-12 and -23 for the treatment of adult and adolescent (≥ 12 to < 18 years of age) patients with moderate-to-severe plaque psoriasis. A phase III study was recently completed i
Autor:
Bruce Randazzo, Y. Wasfi, Yaowei Zhu, Zhenling Yao, Amarnath Sharma, Zhenhua Xu, Yang Chen, Chuanpu Hu, Honghui Zhou
Publikováno v:
Journal of clinical pharmacology. 58(5)
Psoriasis is a common inflammatory skin disorder that requires chronic treatment and is associated with multiple comorbidities. Guselkumab, a human immunoglobulin-G1-lambda monoclonal antibody, binds to interleukin-23 with high specificity and affini
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 23:417-424
The aim of this study was to investigate the influence of several anticancer drugs and investigational multidrug resistance (MDR) reversing agents on the hepatic metabolism of paclitaxel (Taxol) to its primary metabolites, 6alpha-hydroxypaclitaxel (m
Autor:
Esther Bouman-Thio, Qingmin Wang, Bart Frederick, Yaowei Zhu, Honghui Zhou, Joseph C. Marini, Hugh M. Davis, Kevin J. Petty, Monica Keen
Publikováno v:
Clinical drug investigation. 33(4)
Ustekinumab, a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody against interleukin-12/23p40, has been reported to be significantly efficacious in treating patients with moderate-to-severe plaque psoriasis. Although the efficacy and safety
Publikováno v:
Journal of clinical pharmacology. 50(3)
Ustekinumab, a human immunoglobulin G1 kappa (IgG1k) monoclonal antibody that binds with high affinity to human interleukin-12 and interleukin-23, has demonstrated efficacy in patients with psoriasis. The objective of this study was to perform exposu
Autor:
Yaowei Zhu, Chuanpu Hu, Hugh M. Davis, Honghui Zhou, Joseph C. Marini, Sam Liao, Newman Yeilding, Ming Lu, Jennifer Yohrling
Publikováno v:
Journal of clinical pharmacology. 49(2)
The population pharmacokinetics of ustekinumab are characterized in patients with moderate to severe plaque psoriasis in 2 Phase 3 studies (PHOENIX 1 and PHOENIX 2). Serum concentration data from 1937 patients are analyzed to determine pharmacokineti
Publikováno v:
Europe PubMed Central
Purpose: To characterize the population pharmacokinetics of subcutaneous ustekinumab, a human IgG1κ monoclonal antibody against interleukin-12/23p40, using data from a randomized, double-blind, placebo-controlled Phase II study in patients with acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eb02f53cbe057ac0fe637581d3a7b04
http://europepmc.org/abstract/med/21084039
http://europepmc.org/abstract/med/21084039