Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Mark A. Marzinke"'
Autor:
Jenell S, Coleman, Clarissa P, Diniz, Edward J, Fuchs, Mark A, Marzinke, Wutyi, Aung, Rahul P, Bakshi, Homayoon, Farzadegan, Jay H, Bream, Tricia L, Nilles, Sherry, Hudson, Namandjé N, Bumpus, George J, Schwartz, Michael A, Rosenblum, James F, Rooney, Craig W, Hendrix
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 92:89-96
Depot medroxyprogesterone acetate (DMPA) is a widely used contraceptive method. HIV pre-exposure prophylaxis with emtricitabine and tenofovir disoproxil fumarate (F/TDF) is highly effective in reducing HIV acquisition in women. We sought to determine
Publikováno v:
Clinical Pharmacology & Therapeutics. 113:557-564
Autor:
Kelong Han, Mark Baker, Mark Lovern, Prokash Paul, Yuan Xiong, Parul Patel, Katy P. Moore, Ciara S. Seal, Amy G. Cutrell, Ronald D. D'Amico, Paul D. Benn, Raphael J. Landovitz, Mark A. Marzinke, William R. Spreen, Susan L. Ford
Publikováno v:
British journal of clinical pharmacology, vol 88, iss 10
AimTo characterize cabotegravir population pharmacokinetics using data from phase 1, 2 and 3 studies and evaluate the association of intrinsic and extrinsic factors with pharmacokinetic variability.MethodsAnalyses were implemented in NONMEM and R. Co
Autor:
Mark A. Marzinke, Jessica M. Fogel, Zhe Wang, Estelle Piwowar-Manning, Ryan Kofron, Amber Moser, Pradip Bhandari, Ryann Gollings, Lane R. Bushman, Lei Weng, Elias K. Halvas, John Mellors, Peter L. Anderson, Deborah Persaud, Craig W. Hendrix, Marybeth McCauley, Alex R. Rinehart, Marty St Clair, Susan L. Ford, James F. Rooney, Adeola Adeyeye, Suwat Chariyalertsak, Kenneth Mayer, Roberto C. Arduino, Myron S. Cohen, Beatriz Grinsztejn, Brett Hanscom, Raphael J. Landovitz, Susan H. Eshleman
Publikováno v:
Antimicrobial Agents and Chemotherapy. 67
HPTN 083 demonstrated that injectable cabotegravir (CAB) was superior to oral tenofovir disoproxil fumarate-emtricitabine (TDF-FTC) for HIV prevention in cisgender men and transgender women who have sex with men. We previously analyzed 58 infections
Autor:
Ken Ho, Clara Dominguez-Islas, Daniel Szydlo, Stacey Edick, Nicole Macagna, Sharon A. Riddler, Rhonda M. Brand, Cindy E. Jacobson, Lindsay Kramzer, Ratiya P. Kunjara Na Ayudhya, Jeanna Piper, Mark A. Marzinke, Jose Bauermeister, Jeremy Nuttall, Sharon L. Hillier, Craig W. Hendrix
Publikováno v:
Antimicrob Agents Chemother
Data to inform behaviorally congruent delivery of rectal microbicides as lubricants are scant. Dapivirine (DPV) is a nonnucleoside reverse transcriptase inhibitor which has been demonstrated to be well-tolerated and efficacious in multiple clinical t
Autor:
Ryan T. Jarrett, Yuri van der Heijden, Matthew S. Shotwell, Violet Chihota, Mark A. Marzinke, Richard E. Chaisson, Kelly E. Dooley, Gavin J. Churchyard
Publikováno v:
Antimicrobial Agents and Chemotherapy. 67
Isoniazid pharmacokinetics are not yet well-described during once weekly, high-dose administrations with rifapentine (3HP) for latent tuberculosis infection (LTBI). Fewer data describe 3HP with dolutegravir-based antiretroviral therapy for the treatm
Autor:
Manjula Gunawardana, Mariana Remedios-Chan, Debbie Sanchez, Rob Fanter, Simon Webster, Paul Webster, John A. Moss, MyMy Trinh, Martin Beliveau, Christina M. Ramirez, Mark A. Marzinke, Joseph Kuo, Philippe A. Gallay, Marc M. Baum
Publikováno v:
Pharmaceutical research.
Purpose Long-acting formulations of the potent antiretroviral prodrug tenofovir alafenamide (TAF) hold potential as biomedical HIV prevention modalities. Here, we present a rigorous comparison of three animal models, C57BL/6 J mice, beagle dogs, and
Autor:
Sharon L. Achilles, Craig W. Hendrix, Mark A. Marzinke, Jessica Tarleton, Leslie A. Meyn, Beatrice A. Chen
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 85:182-188
Background Depot medroxyprogesterone acetate (DMPA) is a commonly used contraceptive in areas where use of tenofovir disoproxil fumarate and emtricitabine for HIV pre-exposure prophylaxis (PrEP) is increasing. Objectives We aimed to investigate the i
Autor:
Asama Tanaudommongkon, Ayyappa Chaturvedula, Craig W. Hendrix, Edward J. Fuchs, Eugenie Shieh, Rahul P. Bakshi, Mark A. Marzinke
Publikováno v:
British journal of clinical pharmacology. 88(8)
Transgender women (TGW) have been underrepresented in trials and use gender-affirming hormonal therapies (GAHT) that may alter renal function by significantly increasing creatinine clearance. Population pharmacokinetic (popPK) models and simulations
Autor:
Maoji Li, Mark A. Marzinke, Bonnie J. Dye, James P. Hughes, Timothy H. Holtz, Craig W. Hendrix, K. Rivet Amico, Anupong Chitwarakorn, Ethan Wilson, Sharon Mannheimer, Linda-Gail Bekker, Victoria D. Ojeda, Robert M. Grant
Publikováno v:
J Acquir Immune Defic Syndr
We evaluated the relationship between 2 types of social relationships, ie, (1) external support for use of HIV pre-exposure prophylaxis (PrEP) and related study supplies and (2) participants' disclosure of PrEP use and condom use and HIV PrEP adheren