Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ago Ahene"'
Publikováno v:
Cancer Chemotherapy and Pharmacology
Purpose A population pharmacokinetic (PK) analysis of the anti-fibroblast growth factor receptor 2b antibody, bemarituzumab, was performed to evaluate the impact of covariates on the PK and assess whether dose adjustment is necessary for a future pha
Autor:
Yuying Gao, Lucy Liu, Lyndah Dreiling, Helen Collins, Amy W. Hsu, Ago Ahene, Monica Macal, Hong Xiang
Publikováno v:
Cancer Chemotherapy and Pharmacology
Purpose To report population pharmacokinetic (PK) analysis of the phase 1 study (FPA144-001, NCT02318329) and to select a clinical dose and schedule that will achieve an empirical target trough concentration (Ctrough) for an anti-fibroblast growth fa
Autor:
Douglas Clark, Changhua Ji, Ying C. Ou, Xingrong Liu, Jun Zhang, Matthew W. Cooper, Ago Ahene, Su-Chun Hsieh
Publikováno v:
Pharmaceutical Research. 31:809-818
This study was to characterize the pharmacokinetics (PK) and pharmacodynamics (PD) of a chimeric protein, CD4-anchoring bi-functional fusion inhibitor (CD4-BFFI), in monkeys and assess the feasibility for HIV-1 treatment in humans.The serum concentra