Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Yeong-Shiau Pu"'
Autor:
Chien Tien Su, Wei Jen Chen, Pui Lam Ao, Ying Chin Lin, Shu Mei Yang, Yu Mei Hsueh, Chao-Yuan Huang, Horng Sheng Shiue, Yeong-Shiau Pu
Publikováno v:
Toxicology and Applied Pharmacology. 350:11-20
Our recent study found that high urinary total arsenic levels were associated with renal cell carcinoma (RCC). Recent studies demonstrated that low circulating adiponectin was related to RCC. The aim of the present study was to explore the relationsh
Autor:
Yeong-Shiau Pu, Shu Mei Yang, Chao-Yuan Huang, Yu Mei Hsueh, Yi Hsun Hsieh, Ying Chin Lin, Wei Jen Chen, Horng Sheng Shiue
Publikováno v:
Toxicology and Applied Pharmacology. 305:103-110
Our previous study showed that high urinary total arsenic levels were associated with higher odds ratio (OR) for renal cell carcinoma (RCC). Single nucleotide polymorphisms (SNPs) of DNA methyltransferases (DNMTs) might influence DNMT enzyme activity
Autor:
Jason Chia-Hsien Cheng, Yeong-Shiau Pu, Kai-Yuan Tzen, Tsung-Fan Tuan, Pei-Yin Ho, Wei-Lin Liu, Yu-Chieh Tsai, Ann-Lii Cheng
Publikováno v:
Molecular Cancer Therapeutics. 14:810-820
Blockade of EGFR has been proved useful in enhancing the effect of radiotherapy, but the advantages of new-generation EGFR tyrosine kinase inhibitors (TKI) in radiosensitization are not well known. We used two human bladder cancer cells with wild-typ
Autor:
Chia-Che Chang, Wei-Chi Hsu, Chun-Nan Lin, Chi-Chen Lin, Kai-Wei Lin, Yeong-Shiau Pu, A-Mei Huang, Tzyh-Chyuan Hour
Publikováno v:
European Journal of Pharmacology. 740:742-751
Ursolic acid and most of its derivatives are cytotoxic to bladder cancer cells. An ursolic acid derivative, isopropyl 3β-hydroxyurs-12-en-28-oat (UA17), previously reported that it exhibited potent cytotoxicity against bladder cancer cells, NTUB1 ce
Autor:
Horng Sheng Shiue, Yeong-Shiau Pu, Chien I. Chiang, Chao-Yuan Huang, Wei Jen Chen, Ying-Chin Lin, Yu Mei Hsueh, Ya Li Huang
Publikováno v:
Toxicology and Applied Pharmacology. 279:373-379
The association between DNA repair gene polymorphisms and bladder cancer has been widely studied. However, few studies have examined the correlation between urothelial carcinoma (UC) and arsenic or its metabolites. The aim of this study was to examin
Autor:
Chi Hung Chen, Chao-Yuan Huang, Horng Sheng Shiue, Ying Chin Lin, Wei Jen Chen, Yeong-Shiau Pu, Yu Mei Hsueh, Chien Tien Su
Publikováno v:
Toxicology and applied pharmacology. 332
This study was designed to explore the relationship between X-ray repair cross-complementing group 1 ( XRCC1 ) gene polymorphisms and renal cell carcinoma (RCC) and to investigate whether individuals with an XRCC1 risk genotype, a high level of 8-OHd
Autor:
Tzyh-Chyuan Hour, Ying-Chu Lin, Yeong-Shiau Pu, Wen-Jeng Wu, Shiu-Dong Chung, Shu-Pin Huang, Shu-Ju Chuang, Chao-Yuan Huang, Wang-Yi Kang, A-Mei Huang
Publikováno v:
Archives of Toxicology. 89:591-605
Recent studies have shown that docetaxel-based chemotherapy confers a survival benefit in patients with castration-resistant prostate cancer (PC). Also epidermal growth factor receptor (EGFR) was found to have multiple roles in prostatic tumorigenesi
Autor:
Ming-Hong Yen, Chi-Hung Teng, Kai-Wei Lin, Wen-Bin Wu, Yeong-Shiau Pu, Chun-Nan Lin, Chien-Ming Wu, Yu-Chian Chen, A-Mei Huang
Publikováno v:
Biological and Pharmaceutical Bulletin. 37:1191-1198
In an effort to develop potent cyclooxygenase-1 (COX-1) inhibitors used as anticancer agent, a series of 2',5'-dimethoxychalcones was screened to evaluate their antiplatelet effect on human washed platelets suspension. Compound 2 exhibited potent inh
Autor:
Yeong-Shiau Pu, Horng Sheng Shiue, Chao-Yuan Huang, Chi Hung Chen, Chien Tien Su, Ying Chin Lin, Yu Mei Hsueh, Wei Jen Chen
Publikováno v:
Toxicology and Applied Pharmacology. 356:139
Autor:
Yeong-Shiau Pu, Chao-Yuan Huang, Chien-Tien Su, Chi Jung Chung, Yu-Mei Hsueh, Horng Sheng Shiue
Publikováno v:
Toxicology and Applied Pharmacology. 266:254-259
Inter-individual variation in the metabolism of xenobiotics, caused by factors such as cigarette smoking or inorganic arsenic exposure, is hypothesized to be a susceptibility factor for urothelial carcinoma (UC). Therefore, our study aimed to evaluat