Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Yazun Jarrar"'
Autor:
Malik Zihlif, Mustafa Alrabayah, Islam Mohammad Massad, Amer Imraish, Yazun Jarrar, Faysal Massad, Hasan Guzu, Basil Abufares, Afnan Al-Oran, Malik Mohammad Alkharabsheh, Nour Haroon, Mohammad Asa'ad Ismail, Bara'a Qaqish
Publikováno v:
Current Drug Metabolism. 23:1156-1161
Background: Propofol is the most commonly used general anesthetic drug in many countries, including Jordan. However, there is a wide variation in the propofols' dose and response among the patients. Genetic variation in the cytochrome (CYP) 2B6 gene
Autor:
Yazun Jarrar, Ruba Balasmeh, Iyad Al-Sheikh, Hamza Alshaiah, Qais Jarrar, Raad Alani, Sara Abudahab
Publikováno v:
Current Drug Metabolism. 23:666-676
Aims: This study aimed to investigate the effects of consuming Phoenix dactylifera and fasting on the mRNA expression of major hepatic drug-metabolizing enzymes in mice. Methods: Phoenix dactylifera ethanolic extract was analyzed using LC-MS/MS. We u
Publikováno v:
Current Pharmaceutical Design. 28:324-330
Background:Oxandrolone is a synthetic testosterone analogue that is widely used among bodybuilders and athletes. However, oxandrolone causes male infertility. Recently, it was found that metformin reduces the risk of infertility associated with diabe
Autor:
Yazun Jarrar, Marah Alkhalili, Hussam Alhawari, Sara J. Abaalkhail, Sura Alkhalili, Hussein Alhawari, Munther Momani, Ala'eddien Nathir Obeidat, Rand K. Fram
Publikováno v:
Prostaglandins & Other Lipid Mediators. 165:106715
Autor:
Qais Jarrar, Mohammad Al Shhab, Yazun Jarrar, Wisam Naser, Malek Zihlif, Abdulla El Madani, Hanin Moh'd Kalloush, Yahya Jamous, Su-Jun Lee, Sara J. Abaalkhail
Publikováno v:
Fundamental & Clinical Pharmacology. 36:143-149
Thiazolidinediones are well-known anti-diabetic drugs. However, they are not widely used due to their cardiotoxic effects. Therefore, in this study, we aimed to determine the molecular toxicological alterations induced in the mouse hearts after thiaz
Publikováno v:
Current Drug Metabolism. 20:918-923
Background: Mouse Udp-glucuronosyl Transferase (UGT) 2b1 is equivalent to the human UGT2B7 enzyme, which is a phase II drug-metabolising enzyme and plays a major role in the metabolism of xenobiotic and endogenous compounds. This study aimed to find
Publikováno v:
Pharmacogenomics and Personalized Medicine. 12:247-255
Background Testing by pharmacogenomics (PGx) aims to reduce the side-effects of medicines and to optimize therapy. Aim To ascertain the knowledge and attitudes towards PGx among pharmacy students in Jordan and West Bank of Palestine (WBP). Methods Th
Autor:
Yazun Jarrar, Rana Dajani, Malek Zihlif, Ahmad M. Saleh, Sara Abudahab, Nancy Hakooz, Mohammad Al Shahhab
Publikováno v:
Current Drug Metabolism. 20:399-410
Background:Glucuronidation is one of the most important phase II metabolic pathways. It is catalyzed by a family of UDP-glucuronosyltransferase enzymes (UGTs). UGT1A1 and UGT1A7 catalyze the glucuronidation of a diverse range of medications, environm
Publikováno v:
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
Yazun Bashir Jarrar, Luay Al-Essa, Abdulhasib Kilani, Mariam Hasan, Walid Al-Qerem Department of Pharmacy, College of Pharmacy, Al-Zaytoonah University of Jordan, Airport street, Amman, Jordan Background: Diabetic patients have lower capacity to meta
Publikováno v:
International journal of clinical pharmacology and therapeutics. 59(2)
Objective There is a high inter-individual variation in atorvastatin response. This study aimed to identify the influences of the CYP7A1 rs3808607, ABCG8 rs11887534, and ABCG8 rs4148217 genetic variants on the lipid profile and atorvastatin response