Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Xiaopei Cui"'
Autor:
Jie Wang, Zhijian Zheng, Xiaopei Cui, Chaochao Dai, Jiaxin Li, Qunye Zhang, Mei Cheng, Fan Jiang
Publikováno v:
Frontiers in pharmacology. 13
CX-5461, a novel selective RNA polymerase I inhibitor, shows potential anti-inflammatory and immunosuppressive activities. However, the molecular mechanisms underlying the inhibitory effects of CX-5461 on macrophage-mediated inflammation remain to be
Autor:
Guopin, Pan, Jing, Zhang, Yu, Han, Ye, Chen, Xiaosun, Guo, Xiaopei, Cui, Mei, Cheng, Haiqing, Gao, Jianli, Wang, Fan, Jiang
Publikováno v:
Pharmacological Research. 177:106120
CX-5461 is a first-in-class selective RNA polymerase I inhibitor. Previously we found that CX-5461 had anti-inflammatory activities. In this study we characterized potential immunosuppressive effects of CX-5461 and explored the underlying mechanisms.
Autor:
Xiaosun Guo, Wenjing Zhang, Jianli Wang, Tengfei Liu, Fan Jiang, Xiaopei Cui, Ye Chen, Chaochao Dai, Shu Pang
Publikováno v:
European journal of pharmacology. 907
Several lines of studies have indicated that the p53 pathway may have important anti-fibrotic functions. Previously we found that the novel selective RNA polymerase I inhibitor CX-5461 induced a robust response of p53 phosphorylation and activation i
Autor:
Zhi-Cheng Jing, Xiao-Jian Wang, Yang-Yang He, Mingxia Gu, Ming He, Xiaosong Yan, Marlene Rabinovitch, Xiaopei Cui, Hsien Da Huang, Zhao Li, Brendan Gongol, John Y.-J. Shyy, Yuyang Lei, Atul Malhotra, Liang Bai, Jin Zhang, Yuan Shen, Shanshan Chen, Fenling Fan, Chih Hung Chou, Yi-Xin Zhang, Jiao Zhang, Yifei Miao
Publikováno v:
EMBO molecular medicine, vol 12, iss 5
EMBO Molecular Medicine, Vol 12, Iss 5, Pp n/a-n/a (2020)
EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 12, Iss 5, Pp n/a-n/a (2020)
EMBO Molecular Medicine
Endothelial dysfunction is critically involved in the pathogenesis of pulmonary arterial hypertension (PAH) and that exogenously administered microRNA may be of therapeutic benefit. Lower levels of miR‐483 were found in serum from patients with idi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb6364e41ea5ade7e3e7a5e88ca67def
https://escholarship.org/uc/item/20m509zp
https://escholarship.org/uc/item/20m509zp
Autor:
Qihui Yin, Xiaosun Guo, Jianli Wang, Fan Jiang, Xiaopei Cui, Jun Zhang, Weida Lu, Chaochao Dai, Xia Xu, Hua Feng
Publikováno v:
British journal of pharmacology. 178(7)
Background and purpose CX-5461 is a novel selective RNA polymerase I (Pol I) inhibitor. Previously, we found that CX-5461 could inhibit pathological arterial remodelling caused by angioplasty and transplantation. In the present study, we explored the
Autor:
Xiang Ji, Haiqing Gao, Weiling Wang, Yong Xia, Lin Shen, Xiaopei Cui, Yanyan Hu, Xiangju Liu, Mei Cheng, Man Li
Publikováno v:
Ann Transl Med
Background Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease that leads to respiratory failure, and for which there is no effective treatment. Apolipoprotein A-1 (ApoA-1) has been reported to ameliorate the bleomycin (BLM)-induced IPF
The p53 pathway in vasculature revisited: A therapeutic target for pathological vascular remodeling?
Autor:
Xiaosun Guo, Xiaopei Cui, Haiqing Gao, Guopin Pan, Tengfei Liu, Xiaofan Yang, Fan Jiang, Jing Zhang, Mei Cheng, Ye Chen
Publikováno v:
Pharmacological Research. 169:105683
Pathological vascular remodeling contributes to the development of restenosis following intraluminal interventions, transplant vasculopathy, and pulmonary arterial hypertension. Activation of the tumor suppressor p53 may counteract vascular remodelin
Publikováno v:
Biological and Pharmaceutical Bulletin. 35:2192-2197
Grape seed proanthocyanidin extracts (GSPE) belonging to polyphenols, possess various biological effects including anti-inflammation, anti-oxidant, anti-aging, anti-atherosclerosis, etc. GSPE is potential in regulating endothelial function. However,
Publikováno v:
Journal of analytical toxicology. 37(6)
Hair is a useful aid and sometimes even the only matrix in the analytical strategy in drug-facilitated crime (DFC) investigations. In this novel study, segmental hair analysis was performed after a single 10 mg dose of zolpidem was given to 20 Chines