Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Dan Xu"'
Autor:
Dan Xu, Ankith Nair, Charlie Sigston, Chau Ho, Jia Li, Daya Yang, Xinxue Liao, Wei Chen, Ming Kuang, Yanbing Li, Christopher Reid, Haipeng Xiao
Publikováno v:
Cardiovascular Therapeutics. 2022:1-9
Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) have been observed in several large cardiovascular outcome trials to significantly reduce the incidence of major cardiovascular event (MACE) with type 2 diabetic patients. The clinical trials of G
Autor:
You Dan Xu, Linqing Tian, Rebecca Yong Lai, Zihao Li, Eliška Procházková, Junming Ho, Martina H. Stenzel
Publikováno v:
Bioconjugate Chemistry. 33:321-332
Preexisting serum albumin-polymer bioconjugates have been formed either through covalent conjugation or supramolecular interactions. However, the viability of producing a bioconjugate where both covalent conjugation and supramolecular interactions ha
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-8 (2021)
NPJ Vaccines
NPJ Vaccines
Merkel cell carcinoma (MCC) is a rare but aggressive skin cancer with a high mortality rate, while Merkel cell polyomavirus (MCV) has been pointed as the causative agent of MCC. A better prognosis of MCC associated with a high level of antibodies aga
Publikováno v:
Anti-Cancer Drugs
Objective The present study is designed to investigate the expressions of microRNA-143-3p (miR-143-3p) and Lysine acetyltransferase 6A (KAT6A) in acute myeloid leukemia (AML) samples and AML cell lines and to explore the possible effects and underlyi
Autor:
De-Ping Zhao, Xia Lei, Yue-Ying Wang, Ao Xue, Chen-Yu Zhao, Yan-Ming Xu, Yue Zhang, Guo-Liang Liu, Fang Geng, Hong-Dan Xu, Ning Zhang
Publikováno v:
Frontiers in Pharmacology. 13
Alzheimer’s disease (AD) is a growing concern in modern society, and there is currently a lack of effective therapeutic drugs. Sagacious Confucius’ Pillow Elixir (SCPE) has been studied for the treatment of neurodegenerative diseases such as AD.
Autor:
Zixi Yi, Zhongqiang Yao, Dan Xu, Chuanhui Xu, Wenqiang Fang, Zhanfei Guo, Yong Wang, Jianlin Huang, Qin Li, Hong Zhang, Anbin Huang, Lijun Wu, Zhenbiao Wu, Huifang Guo, Fengxiao Zhang, Jing Lu, Zhenchun Zhang, Zhongming Yu, Zhanyun Da, Li Luo, Bin Wu, Henglian Wu, Lin Zeng, Rong Mu
Publikováno v:
Vaccines; Volume 10; Issue 10; Pages: 1604
The coronavirus disease 2019 (COVID-19) pandemic has imposed enormous morbidity and mortality burdens. Patients with rheumatic diseases (RDs) are vulnerable to the COVID-19 infection, given their immunocompromised status. Ensuring acceptance of the C
Autor:
Yunge Lou, Rui Wang, Na Yang, Jiye Aa, Haokai Zhao, Guangji Wang, Dan Xu, Yuan Xie, Yirui Zhang, Ran Zhang
Publikováno v:
Drug Metabolism and Disposition. 49:770-779
Silybin is widely used as a hepatoprotective agent in various liver disease therapies and has been previously identified as a CYP3A inhibitor. However, little is known about the effect of silybin on CYP3A and the regulatory mechanism during high-fat-
Publikováno v:
Tropical Journal of Pharmaceutical Research. 18:1041-1047
Purpose: To investigate the effect of thiamine triethylorthoformate conjugate (TTO) on Parkinson disease (PD) in vitro and in vivo in a mice model. Methods: The effect of TTO on behavioural changes in PD mouse model was studied using pole, traction a
Swimming exercise is a promising early intervention for autism-like behavior in Shank3 deletion rats
Autor:
Dan Xu, Yunchen Meng, Shasha An, Wenshu Meng, Hanran Li, Weinan Zhang, Yaqi Xue, Xinyu Lan, Xiaoxi Wang, Mingjuan Li, Xiaoyan Zhang, Zhang Zhihao, Yu Zhao, Haodong Yang, Chen Zhang, Rong Zhang, Zhiping Zhen
Publikováno v:
CNS neurosciencetherapeuticsREFERENCES. 29(1)
SHANK3 is an important excitatory postsynaptic scaffold protein, and its mutations lead to genetic cause of neurodevelopmental diseases including autism spectrum disorders (ASD), Philan McDermid syndrome (PMS), and intellectual disability (ID). Early
Autor:
Pei Liu, Cha Lin, Zheyu Liu, Chenchen Zhu, Zhongda Lin, Dan Xu, Jian Chen, Qian Huang, Chuan-Yuan Li, Linlin Hou, Ji-An Pan, Xinjian Liu
Publikováno v:
Cellular and Molecular Life Sciences. 79
Immune checkpoint blockade therapy has drastically improved the prognosis of certain advanced-stage cancers. However, low response rates and immune-related adverse events remain important limitations. Here, we report that inhibiting ALG3, an a-1,3-ma