Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Xiaoliang Jin"'
Autor:
Xiaodan Hong, Zuhuan Cai, Fang Zhou, Xiaoliang Jin, Guangji Wang, Bingchen Ouyang, Jingwei Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Tenofovir (TFV) ester prodrugs, a class of nucleotide analogs (NAs), are the first-line clinical anti-hepatitis B virus (HBV) drugs with potent antiviral efficacy, low resistance rate and high safety. In this work, three marketed TFV ester drugs, ten
Externí odkaz:
https://doaj.org/article/de76689d8675444cb094691580e3db93
Autor:
Jiye A, Xiaoliang Jin, Zhen-Zhong Wang, Yuqing Zhao, Guangji Wang, Jiankun Wang, Jianliang Geng, Bingchen Ouyang, Wen-Zhe Huang, Shu-Yao Wang, Fei Fei, Pei Wang, Yan-Jing Li, Wei Xiao, Ying Peng, Ting Geng
Publikováno v:
Chinese Journal of Natural Medicines. 15:775-784
Ginkgo diterpene lactones meglumine injection (GDLI) is a commercially available product used for neuroprotection. However, the pharmacokinetic properties of the prototypes and hydrolyzed carboxylic forms of the primary components in GDLI, i.e., gink
Autor:
Yan Liu, Yuanwei Jia, Fang Zhou, Lan Yao, Xiaoliang Jin, Jingwei Zhang, Guangji Wang, Cheng Chen
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 158
Parecoxib (PX), a prodrug of valdecoxib (VX), is an injectable selective COX-2 inhibitor, and is recommended for the treatment of cancer pain. PX can be rapidly hydrolyzed into its active metabolite VX, and VX is further metabolized into hydroxylated
Autor:
Guangji Wang, Jianguo Sun, Fang Zhou, Xiaoliang Jin, Ying Peng, Qianying Chen, Jingwei Zhang, Ming-min Cai, Lan Yao
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 146
Etimicin (ETM), which belongs to the newest generation of aminoglycosides (AGs), has been proven to not only maintain but also strengthen the advantages of former AGs with relatively less toxicity. Now, it is widely applied for the treatment of bacte
Autor:
Jingwei Zhang, Bingchen Ouyang, Le Zhen, Jianguo Sun, Xiaoliang Jin, Fang Zhou, Guangji Wang, Qianying Chen, Ying Peng
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 146
Tenofovir (TFV), a first-line anti-viral agent, has been prepared as various forms of prodrugs for better bioavailability, lower systemic exposure and higher target cells loading of TFV to enhance efficacy and reduce toxicity. TFV undergoes intracell
Autor:
Guangji Wang, Yu Wang, Jiye Aa, Ke-Rong Zhang, Bingchen Ouyang, Jianguo Sun, Zhen-Zhong Wang, Xiaoliang Jin, Wei Xiao, Shiyin Gu, Ying Peng, Yunxi Zhong
Publikováno v:
Scientific Reports
Guizhi Fuling capsule (GZFL), a traditional Chinese medicine formulation, is widely used in China to relieve pain from dysmenorrhea and is now in a Phase II clinical trial in the USA. Due to the low exposure of the five main medicative ingredients (a