Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Betül Kaya Çavuşoğlu"'
Publikováno v:
Letters in Drug Design & Discovery. 18:471-479
Background: Dibenzofuran ring is a typical heterocyle that is found in many natural sources and its derivatives exhibit a wide scale of biological applications similar to its analog ring systems; furan and benzofuran. Materials and Methods: Novel N-(
Autor:
Begüm Nurpelin Sağlık, Zafer Asım Kaplancıklı, Yusuf Özkay, Derya Osmaniye, Serkan Levent, Ulviye Acar Çevik, Betül Kaya Çavuşoğlu
Publikováno v:
RSC Med Chem
Monoamine oxidases (MAOs) are important drug targets for the management of neurological disorders. Herein, a series of new 1,3,4-thiadiazole derivatives bearing various alkyl/arylamine moieties as MAO inhibitors were designed and synthesized. All of
Autor:
Betül Kaya Çavuşoğlu, Ulviye Acar Çevik, Derya Osmaniye, Yusuf Özkay, Zafer Asım Kaplancıklı, Begüm Nurpelin Sağlık, Serkan Levent
Publikováno v:
Molecules
Volume 25
Issue 18
Molecules, Vol 25, Iss 4312, p 4312 (2020)
Volume 25
Issue 18
Molecules, Vol 25, Iss 4312, p 4312 (2020)
Dementia is a neurological condition commonly correlated with Alzheimer&rsquo
s disease (AD), and it is seen with many other central nervous system (CNS) disorders. The restricted number of medications is not appropriate to offer enough relief t
s disease (AD), and it is seen with many other central nervous system (CNS) disorders. The restricted number of medications is not appropriate to offer enough relief t
Autor:
Ulviye Acar Çevik, Yusuf Özkay, Begüm Nurpelin Sağlık, Derya Osmaniye, Zafer Asım Kaplancıklı, Betül Kaya Çavuşoğlu, Sinem Ilgın, Serkan Levent
Publikováno v:
Molecules, Vol 25, Iss 1642, p 1642 (2020)
Molecules
Volume 25
Issue 7
Molecules
Volume 25
Issue 7
In the last step of estrogen biosynthesis, aromatase enzyme catalyzes the conversion of androgens to estrogens. Aromatase inhibition is an important way to control estrogen-related diseases and estrogen levels. In this study, sixteen of benzimidazole
Autor:
Derya Osmaniye, Begüm Nurpelin Sağlık, Zafer Asım Kaplancıklı, Yusuf Özkay, Betül Kaya Çavuşoğlu, Ulviye Acar Çevik, Abdullah Burak Karaduman, Serkan Levent
Karaduman, Abdullah Burak/0000-0002-0434-1334
WOS: 000519092100001
PubMed: 32159244
Aromatase is involved in the biosynthesis of estrogen and thus is a critical target for breast cancer. in this study, to identify new aromatase enzyme
WOS: 000519092100001
PubMed: 32159244
Aromatase is involved in the biosynthesis of estrogen and thus is a critical target for breast cancer. in this study, to identify new aromatase enzyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be114ce695246006062384a6f5a413b6
https://hdl.handle.net/11421/23980
https://hdl.handle.net/11421/23980
Autor:
Ulviye Acar Çevik, Begüm Nurpelin Sağlık, Abdullah Burak Karaduman, Derya Osmaniye, Yusuf Özkay, Serkan Levent, Betül Kaya Çavuşoğlu, Zafer Asım Kaplancıklı
Publikováno v:
Acta Pharmaceutica, Vol 70, Iss 4, Pp 499-513 (2020)
WOS: 000535907700005
PubMed: 32412436
The synthesis of new N-(5-substituted-1,3,4-thiadiazol-2-yl)-2-[5-(substituted amino)-1,3,4-thiadiazol-2-yl)thiolacetamide derivatives and investigation of their anticancer activities were the aims of t
PubMed: 32412436
The synthesis of new N-(5-substituted-1,3,4-thiadiazol-2-yl)-2-[5-(substituted amino)-1,3,4-thiadiazol-2-yl)thiolacetamide derivatives and investigation of their anticancer activities were the aims of t
Autor:
Ulviye Acar Çevik, Begüm Nurpelin Sağlık, Derya Osmaniye, Zafer Asım Kaplancıklı, Betül Kaya Çavuşoğlu, Yusuf Özkay, Serkan Levent, Gülhan Turan
Publikováno v:
Molecules
Volume 24
Issue 13
Molecules, Vol 24, Iss 13, p 2392 (2019)
Volume 24
Issue 13
Molecules, Vol 24, Iss 13, p 2392 (2019)
WOS: 000476700300046
PubMed ID: 31261693
Alzheimer's disease (AD) is the most common of the degenerative brain diseases and is described together with the impairment of cognitive function. Patients with AD lose the capability to code new me
PubMed ID: 31261693
Alzheimer's disease (AD) is the most common of the degenerative brain diseases and is described together with the impairment of cognitive function. Patients with AD lose the capability to code new me
Autor:
Yusuf Özkay, Derya Osmaniye, Zafer Asım Kaplancıklı, Betül Kaya Çavuşoğlu, Begüm Nurpelin Sağlık, Ulviye Acar Çevik, Serkan Levent
Publikováno v:
Molecules
Volume 24
Issue 5
Molecules, Vol 24, Iss 5, p 861 (2019)
Volume 24
Issue 5
Molecules, Vol 24, Iss 5, p 861 (2019)
Alzheimer&rsquo
s disease (AD), one of the main causes of aged dementia, is a progressive and degenerative neurological disorder characterized by loss of cognition and memory. Although the symptomatic treatment of AD, particularly acetylcholines
s disease (AD), one of the main causes of aged dementia, is a progressive and degenerative neurological disorder characterized by loss of cognition and memory. Although the symptomatic treatment of AD, particularly acetylcholines
Autor:
Ahmet Cagri Karaburun, Serkan Levent, Derya Osmaniye, Ulviye Acar Çevik, Yusuf Özkay, Zafer Asım Kaplancıklı, Betül Kaya Çavuşoğlu, Mustafa Behçet, Begüm Nurpelin Sağlık, Ali Savaş Koparal
Publikováno v:
Molecules, Vol 23, Iss 12, p 3129 (2018)
Molecules
Volume 23
Issue 12
Molecules
Volume 23
Issue 12
WOS: 000454523000079
PubMed ID: 30501053
With the goal of obtaining a novel bioactive compound with significant antifungal activity, a series of 1,3,4-thiadiazole derivatives (3a-3l) were synthesized and characterized. Due to thione-thiol t
PubMed ID: 30501053
With the goal of obtaining a novel bioactive compound with significant antifungal activity, a series of 1,3,4-thiadiazole derivatives (3a-3l) were synthesized and characterized. Due to thione-thiol t
Autor:
Derya Osmaniye, Serkan Levent, Zafer Asım Kaplancıklı, Yusuf Özkay, Begüm Nurpelin Sağlık, Ulviye Acar Çevik, Betül Kaya Çavuşoğlu
Publikováno v:
Archiv der Pharmazie. 354:2000273
A new series of chalcones (1-9) possessing an SO2 CH3 COX-2 pharmacophore at the para position of the C-1 phenyl ring was synthesized via the Claisen-Schmidt condensation reaction and examined for their inhibition potential against cyclooxygenase (CO