Zobrazeno 1 - 2
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pro vyhledávání: '"Trine V. Axelsen"'
Publikováno v:
Vaccine. 29:3260-3269
Alzheimer's disease (AD) is characterized by neurofibrillary tangles, consisting of hyperphosphorylated tau protein and senile plaques, which are consisting mainly of amyloid-β (Aβ). Attempts to generate a safe vaccine against Aβ rely on both B- a
Autor:
Svend Birkelund, Gunna Christiansen, Michael Ploug, Trine V Axelsen, Arne Holm, Ida Elisabeth Holm
Publikováno v:
Axelsen, T V, Holm, A, Birkelund, S, Christiansen, G, Ploug, M & Holm, I E 2009, ' Specific recognition of the C-terminal end of A beta 42 by a high affinity monoclonal antibody ', Molecular Immunology, vol. 46, no. 11-12, pp. 2267-73 . https://doi.org/10.1016/j.molimm.2009.04.007
Udgivelsesdato: 2009-Jul The neurotoxic peptide A beta(42) is derived from the amyloid precursor protein by proteolytic cleavage and is deposited in the brain of patients suffering from Alzheimer's disease (AD). In this study we generate a high affin