Zobrazeno 1 - 10
of 31
pro vyhledávání: 'Lüllmann-Rauch, Renate'
Autor:
Heike Wolf, Markus Damme, Stijn Stroobants, Rudi D'Hooge, Hans Christian Beck, Irm Hermans-Borgmeyer, Renate Lüllmann-Rauch, Thomas Dierks, Torben Lübke
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 9, Pp 1015-1028 (2016)
Fucosidosis is a rare lysosomal storage disorder caused by the inherited deficiency of the lysosomal hydrolase α-L-fucosidase, which leads to an impaired degradation of fucosylated glycoconjugates. Here, we report the generation of a fucosidosis mou
Externí odkaz:
https://doaj.org/article/138a1d71f754489d931af1f83c6469a3
Autor:
Paul Saftig, Sönke Rudnik, Irm Hermans-Borgmeyer, Markus Glatzel, Thuy Linh Nguyen, Christian Bernreuther, Janna Schneppenheim, Bernd Schröder, Renate Lüllmann-Rauch
Publikováno v:
Oncotarget
// Thuy Linh Nguyen 1 , Janna Schneppenheim 2 , Sonke Rudnik 1 , Renate Lullmann-Rauch 2 , Christian Bernreuther 3 , Irm Hermans-Borgmeyer 4 , Markus Glatzel 3 , Paul Saftig 1 and Bernd Schroder 1 1 Biochemical Institute, Christian Albrechts Universi
Akademický článek
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Autor:
Gregor Martin, Radislav Sedlacek, Stefan Rose-John, Miryam Müller, R Barikbin, Sebastian Wetzel, Julia Köhn-Gaone, Olga Zbodakova, Renate Lüllmann-Rauch, Paul Saftig, Ivo Leuschner, Birte Wöhner, Gisa Tiegs, Juri Bergmann, Karel Chalupsky, Janina E.E. Tirnitz-Parker, Dirk Schmidt-Arras
Publikováno v:
Oncotarget
// Miryam Muller 1,* , Sebastian Wetzel 1,* , Julia Kohn-Gaone 2 , Karel Chalupsky 3 , Renate Lullmann-Rauch 4 , Roja Barikbin 5 , Juri Bergmann 1,6 , Birte Wohner 1 , Olga Zbodakova 3 , Ivo Leuschner 7 , Gregor Martin 3,9 , Gisa Tiegs 5 , Stefan Ros
Autor:
Renate Lüllmann-Rauch, Judith Blanz, Julia Mayerle, Ilya Gukovsky, Samuel W. French, Olga Vagin, Sudarshan R. Malla, Elmira Tokhtaeva, Iskandar Yakubov, Markus M. Lerch, Viola Oorschot, Matthias Sendler, Olga A. Mareninova, David W. Dawson, Judith Klumperman, Anna S. Gukovskaya
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and molecular gastroenterology and hepatology, vol 1, iss 6
ResearcherID
Cellular and Molecular Gastroenterology and Hepatology, Vol 1, Iss 6, Pp 678-694 (2015)
Cellular and molecular gastroenterology and hepatology, 1(6), 678. Elsevier Inc.
Cellular and molecular gastroenterology and hepatology, vol 1, iss 6
ResearcherID
Cellular and Molecular Gastroenterology and Hepatology, Vol 1, Iss 6, Pp 678-694 (2015)
Cellular and molecular gastroenterology and hepatology, 1(6), 678. Elsevier Inc.
Background & Aims: The pathogenic mechanism of pancreatitis is poorly understood. Recent evidence implicates defective autophagy in pancreatitis responses; however, the pathways mediating impaired autophagy in pancreas remain largely unknown. Here, w
PURPOSE. Retinal degeneration is a common feature of several lysosomal storage disorders, including the mucopolysaccharidoses, a group of metabolic disorders that is characterized by widespread accumulation of glycosaminoglycans due to lysosomal enzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a899de0b25eb16d98389942cb29a949
https://pub.uni-bielefeld.de/record/2904124
https://pub.uni-bielefeld.de/record/2904124
Autor:
Peter Heimann, Thomas Dierks, Markus Damme, Steven U. Walkley, Tomo Sawada, Theresa Ortkras, Björn Kowalewski, Renate Lüllmann-Rauch
Publikováno v:
Human molecular genetics. 24(7)
Deficiency of arylsulfatase G (ARSG) leads to a lysosomal storage disease in mice resembling biochemical and pathological features of the mucopolysaccharidoses and particularly features of mucopolysaccharidosis type III (Sanfilippo syndrome). Here we
Autor:
P. Fredman, Ulrich Matzner, Rudi D'Hooge, P.P. De Deyn, Dieter Hartmann, Renate Lüllmann-Rauch, F. Rothert, Volkmar Gieselmann, Jan-Eric Månsson, R. Coenen
Publikováno v:
Gene therapy
Arylsulfatase A (ASA) knockout mice represent an animal model for the lysosomal storage disease metachromatic leukodystrophy (MLD). Stem cell gene therapy with bone marrow overexpressing the human ASA cDNA from a retroviral vector resulted in the exp
Autor:
Jérémie Gautheron, Stefan Rose-John, Matthias Lutz, Christoph Jacoby, Florian Reisinger, Hans-Joerg Hippe, Dieter Adam, Christoph Roderburg, Andreas Linkermann, Mihael Vucur, Justyna Sosna, Mark Luedde, Nadine Borg, Ulrich Flögel, Monika Julia Wolf, Natalie Carter, Mathias Heikenwalder, Tom Luedde, Norbert Frey, Renate Lüllmann-Rauch
Aims Programmed necrosis (necroptosis) represents a newly identified mechanism of cell death combining features of both apoptosis and necrosis. Like apoptosis, necroptosis is tightly regulated by distinct signalling pathways. A key regulatory role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3625612ef9e64d8333f3b5ccf6660593
https://doi.org/10.5167/uzh-154187
https://doi.org/10.5167/uzh-154187
Publikováno v:
Acta Neuropathologica. 101:491-498
Metachromatic leukodystrophy of humans is an inherited sulfatide lipidosis due to deficiency of arylsulfatase A (ASA). As an animal model, ASA(-/-) mice have been generated. A previous study showed that the mice lose most of their spiral (acoustic) g